Implementation of the scregclust algorithm described in Larsson, Held, et al. (2024) <doi:10.1038/s41467-024-53954-3> which reconstructs regulatory programs of target genes in scRNA-seq data. Target genes are clustered into modules and each module is associated with a linear model describing the regulatory program.

Given a likelihood provided by the user, this package applies it to a given matrix dataset in order to find change points in the data that maximize the sum of the likelihoods of all the segments. This package provides a handful of algorithms with different time complexities and assumption compromises so the user is able to choose the best one for the problem at hand. The implementation of the segmentation algorithms in this package are based on the paper by Bruno M. de Castro, Florencia Leonardi (2018) <arXiv:1501.01756>. The Berlin weather sample dataset was provided by Deutscher Wetterdienst <https://dwd.de/>. You can find all the references in the Acknowledgments section of this package's repository via the URL below.

Estimate the four parameters of stable laws using maximum likelihood method, generalised method of moments with finite and continuum number of points, iterative Koutrouvelis regression and Kogon-McCulloch method. The asymptotic properties of the estimators (covariance matrix, confidence intervals) are also provided.

Applies re-sampled kernel density method to detect vote fraud. It estimates the proportion of coarse vote-shares in the observed data relative to the null hypothesis of no fraud.

This package provides a pipeline for estimating the stellar age, mass, and radius given observational effective temperature, [Fe/H], and astroseismic parameters. The results are obtained adopting a maximum likelihood technique over a grid of pre-computed stellar models, as described in Valle et al. (2014) <doi:10.1051/0004-6361/201322210>.

This package provides a set of functions to calculate sample size for two-sample difference in means tests. Does adjustments for either nonadherence or variability that comes from using data to estimate parameters.

Extended Susceptible-Exposed-Infected-Recovery Model for handling high false negative rate and symptom based administration of diagnostic tests. <doi:10.1101/2020.09.24.20200238>.

This package provides a spatial population can be generated based on spatially varying regression model under the assumption that observations are collected from a uniform two-dimensional grid consist of (m * m) lattice points with unit distance between any two neighbouring points. For method details see Chao, Liu., Chuanhua, Wei. and Yunan, Su. (2018).<DOI:10.1080/10485252.2018.1499907>. This spatially generated data can be used to test different issues related to the statistical analysis of spatial data. This generated spatial data can be utilized in geographically weighted regression analysis for studying the spatially varying relationships among the variables.

This package provides a computational framework for analyzing mutations in immunoglobulin (Ig) sequences. Includes methods for Bayesian estimation of antigen-driven selection pressure, mutational load quantification, building of somatic hypermutation (SHM) models, and model-dependent distance calculations. Also includes empirically derived models of SHM for both mice and humans. Citations: Gupta and Vander Heiden, et al (2015) <doi:10.1093/bioinformatics/btv359>, Yaari, et al (2012) <doi:10.1093/nar/gks457>, Yaari, et al (2013) <doi:10.3389/fimmu.2013.00358>, Cui, et al (2016) <doi:10.4049/jimmunol.1502263>.

Estimation and inference for parameters in a Gaussian copula model, treating the univariate marginal distributions as nuisance parameters as described in Hoff (2007) <doi:10.1214/07-AOAS107>. This package also provides a semiparametric imputation procedure for missing multivariate data.

This package provides a Bayesian framework for inferring influenza infection status from serial antibody measurements. Jointly estimates season-specific infection probabilities, antibody boosting and waning after infection, and baseline hemagglutination inhibition (HAI) titer distributions via Markov chain Monte Carlo (MCMC). Supports multi-season analysis and subgroup comparisons via a group_by interface. See Tsang et al. (2022) <doi:10.1038/s41467-022-29310-8> for methodological details.

For a single, known pathogen phylogeny, provides functions for enumeration of the set of compatible epidemic transmission trees, and for uniform sampling from that set. Optional arguments allow for incomplete sampling with a known number of missing individuals, multiple sampling, and known infection time limits. Always assumed are a complete transmission bottleneck and no superinfection or reinfection. See Hall and Colijn (2019) <doi:10.1093/molbev/msz058> for methodology.

More easy to get intersection, union or complementary set and combinations.

Supporting materials for a course and book on data visualization. It contains utility functions for graphs and several sample data sets. See Healy (2019) <ISBN 978-0691181622>.

Stochastic dominance tests help ranking different distributions. The package implements the consistent test for stochastic dominance by Barrett and Donald (2003) <doi:10.1111/1468-0262.00390>. Specifically, it implements Barrett and Donald's Kolmogorov-Smirnov type tests for first- and second-order stochastic dominance based on bootstrapping 2 and 1.

This package provides functions that automate accessing, downloading and exploring Soil Moisture and Ocean Salinity (SMOS) Level 4 (L4) data developed by Barcelona Expert Center (BEC). Particularly, it includes functions to search for, acquire, extract, and plot BEC-SMOS L4 soil moisture data downscaled to ~1 km spatial resolution. Note that SMOS is one of Earth Explorer Opportunity missions by the European Space Agency (ESA). More information about SMOS products can be found at <https://earth.esa.int/eogateway/missions/smos/data>.

Complex machine learning models are often hard to interpret. However, in many situations it is crucial to understand and explain why a model made a specific prediction. Shapley values is the only method for such prediction explanation framework with a solid theoretical foundation. Previously known methods for estimating the Shapley values do, however, assume feature independence. This package implements methods which accounts for any feature dependence, and thereby produces more accurate estimates of the true Shapley values. An accompanying Python wrapper ('shaprpy') is available through PyPI.

Collection of custom input controls and user interface components for Shiny applications. Give your applications a unique and colorful style !

Utility functions for scale-dependent and alternative hyperpriors. The distribution parameters may capture location, scale, shape, etc. and every parameter may depend on complex additive terms (fixed, random, smooth, spatial, etc.) similar to a generalized additive model. Hyperpriors for all effects can be elicitated within the package. Including complex tensor product interaction terms and variable selection priors. The basic model is explained in in Klein and Kneib (2016) <doi:10.1214/15-BA983>.

Implementation of deep learningâ based changepoint detection algorithm designed for time series with smooth local fluctuations. The method fits localized feedâ forward neural networks to approximate the underlying smooth component and constructs a residualâ based detector that isolates abrupt structural changes. A fully dataâ adaptive empirical cumulative distribution function (ECDF) based thresholding rule and refinement procedures yield accurate changepoint localization without parametric assumptions on noise or trend structure.

This package provides flexible and efficient tools for integrating external risk scores into Cox proportional hazards models while accounting for population heterogeneity. Enables robust estimation, improved predictive accuracy, and user-friendly workflows for modern survival analysis. For more information, see Wang et al. (2023) <doi:10.48550/arXiv.2302.11123>.

Edit SVG files created in Inkscape by replacing placeholders (e.g. a rectangle element or in a text box) by ggplot2 objects, images or text. This helps automate the creation of figures with complex layouts.

Sensitivity analysis in structural equation modeling using influence measures and diagnostic plots. Support leave-one-out casewise sensitivity analysis presented by Pek and MacCallum (2011) <doi:10.1080/00273171.2011.561068> and approximate casewise influence using scores and casewise likelihood. An introduction to the package can be found in Cheung and Lai (2026) <doi:10.1080/00273171.2026.2634293>.

Generates binary test data based on Item Response Theory using the two-parameter logistic model (Lord, 1980 <doi:10.4324/9780203056615>). Useful functions for test equating are included, e.g. functions for generating internal and external common items between test forms and a function to create a linkage plans between those forms. Ancillary functions for generating true item and person parameters as well as for calculating the probability of a person correctly answering an item are also included.