This package provides methods to detect genetic markers involved in biological adaptation. pcadapt provides statistical tools for outlier detection based on Principal Component Analysis. Implements the method described in (Luu, 2016) <DOI:10.1111/1755-0998.12592> and later revised in (Privé, 2020) <DOI:10.1093/molbev/msaa053>.

In causal mediation analysis with multiple causally ordered mediators, a set of path-specific effects are identified under standard ignorability assumptions. This package implements an imputation approach to estimating these effects along with a set of bias formulas for conducting sensitivity analysis (Zhou and Yamamoto <doi:10.31235/osf.io/2rx6p>). It contains two main functions: paths() for estimating path-specific effects and sens() for conducting sensitivity analysis. Estimation uncertainty is quantified using the nonparametric bootstrap.

Deterministic Pena-Yohai initial estimator for robust S estimators of regression. The procedure is described in detail in Pena, D., & Yohai, V. (1999) <doi:10.2307/2670164>.

Visualize event logs using directed graphs, i.e. process maps. Part of the bupaR framework.

This package contains functions to simulate the most commonly used SAS® procedures. Specifically, the package aims to simulate the functionality of proc freq', proc means', proc ttest', proc reg', proc transpose', proc sort', and proc print'. The simulation will include recreating all statistics with the highest fidelity possible.

This package provides a versatile R visualization package that empowers researchers with comprehensive visualization tools for seamlessly mapping peptides to protein sequences, identifying distinct domains and regions of interest, accentuating mutations, and highlighting post-translational modifications, all while enabling comparisons across diverse experimental conditions. Potential applications of PepMapViz include the visualization of cross-software mass spectrometry results at the peptide level for specific protein and domain details in a linearized format and post-translational modification coverage across different experimental conditions; unraveling insights into disease mechanisms. It also enables visualization of Major histocompatibility complex-presented peptide clusters in different antibody regions predicting immunogenicity in antibody drug development.

Sample size calculations in causal inference with observational data are increasingly desired. This package is a tool to calculate sample size under prespecified power with minimal summary quantities needed.

An implementation of data analysis tools for samples of symmetric or Hermitian positive definite matrices, such as collections of covariance matrices or spectral density matrices. The tools in this package can be used to perform: (i) intrinsic wavelet transforms for curves (1D) or surfaces (2D) of Hermitian positive definite matrices with applications to dimension reduction, denoising and clustering in the space of Hermitian positive definite matrices; and (ii) exploratory data analysis and inference for samples of positive definite matrices by means of intrinsic data depth functions and rank-based hypothesis tests in the space of Hermitian positive definite matrices.

This repository contains the codes for using the predictive accuracy comparison tests developed in Pitarakis, J. (2023) <doi:10.1017/S0266466623000154>.

This package provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) <doi:10.1177/1740774511408748> for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.

Currently incorporate the generalized odds-rate model (a type of linear transformation model) for interval-censored data based on penalized monotonic B-Spline. More methods under other semiparametric models such as cure model or additive model will be included in future versions. For more details see Lu, M., Liu, Y., Li, C. and Sun, J. (2019) <arXiv:1912.11703>.

We provide comprehensive draft data for major professional sports leagues, including the National Football League (NFL), National Basketball Association (NBA), and National Hockey League (NHL). It offers access to both historical and current draft data, allowing for detailed analysis and research on player biases and player performance. The package is useful for sports fans and researchers interested in identifying biases and trends within scouting reports. Created by web scraping data from leading websites that cover professional sports player scouting reports, the package allows users to filter and summarize data for analytical purposes. For further details on the methods used, please refer to Wickham (2022) "rvest: Easily Harvest (Scrape) Web Pages" <https://CRAN.R-project.org/package=rvest> and Harrison (2023) "RSelenium: R Bindings for Selenium WebDriver" <https://CRAN.R-project.org/package=RSelenium>.

An R-Shiny application implementing a method of sexing the human os coxae based on logistic regressions and Bruzek's nonmetric traits <doi:10.1002/ajpa.23855>.

Data are partitioned (clustered) into k clusters "around medoids", which is a more robust version of K-means implemented in the function pam() in the cluster package. The PAM algorithm is described in Kaufman and Rousseeuw (1990) <doi:10.1002/9780470316801>. Please refer to the pam() function documentation for more references. Clustered data is plotted as a split heatmap allowing visualisation of representative "group-clusters" (medoids) in the data as separated fractions of the graph while those "sub-clusters" are visualised as a traditional heatmap based on hierarchical clustering.

Allows users to derive multi-objective weights from pairwise comparisons, which research shows is more repeatable, transparent, and intuitive other techniques. These weights can be rank existing alternatives or to define a multi-objective utility function for optimization.

Test-based Image structural similarity measure and test of independence. This package implements the key functions of two tasks: (1) computing image structural similarity measure PSSIM of Wang, Maldonado and Silwal (2011) <DOI:10.1016/j.csda.2011.04.021>; and (2) test of independence between a response and a covariate in presence of heteroscedastic treatment effects proposed by Wang, Tolos, and Wang (2010) <DOI:10.1002/cjs.10068>.

Create and customize interactive phylogenetic trees using the phylocanvas JavaScript library and the htmlwidgets package. These trees can be used directly from the R console, from RStudio', in Shiny apps, and in R Markdown documents. See <http://phylocanvas.org/> for more information on the phylocanvas library.

This wrapper houses PathLit API endpoints for R. The usage of these endpoints require the use of an API key which can be obtained at <https://www.pathlit.io/docs/cli/>.

This package provides data set and functions for exploration of Multiple Indicator Cluster Survey (MICS) 2014 Child questionnaire data for Punjab, Pakistan (<http://www.mics.unicef.org/surveys>).

R package to compute Incoming Solar Radiation (insolation) for palaeoclimate studies. Features three solutions: Berger (1978), Berger and Loutre (1991) and Laskar et al. (2004). Computes daily-mean, season-averaged and annual means and for all latitudes, and polar night dates.

Build and manipulate partially ordered sets (posets), to perform some data analysis on them and to implement multi-criteria decision making procedures. Several efficient ways for generating linear extensions are implemented, together with functions for building mutual ranking probabilities, incomparability, dominance and separation scores (Fattore, M., De Capitani, L., Avellone, A., Suardi, A. (2024). A fuzzy posetic toolbox for multi-criteria evaluation on ordinal data systems. ANNALS OF OPERATIONS RESEARCH <doi:10.1007/s10479-024-06352-3>).

Useful set of tools for plotting network diagrams in any kind of project.

Includes functions to wrap most endpoints of the PaleobioDB API and to visualize and process the obtained fossil data. The API documentation for the Paleobiology Database can be found at <https://paleobiodb.org/data1.2/>.

An implementation of a non-parametric statistical model using a parallelised Monte Carlo sampling scheme. The method implemented in this package allows non-parametric inference to be regularized for small sample sizes, while also being more accurate than approximations such as variational Bayes. The concentration parameter is an effective sample size parameter, determining the faith we have in the model versus the data. When the concentration is low, the samples are close to the exact Bayesian logistic regression method; when the concentration is high, the samples are close to the simplified variational Bayes logistic regression. The method is described in full in the paper Lyddon, Walker, and Holmes (2018), "Nonparametric learning from Bayesian models with randomized objective functions" <arXiv:1806.11544>.