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Conduct a priori power analyses via Monte-Carlo style data simulation for linear and generalized linear mixed-effects models (LMMs/GLMMs). Provides a user-friendly workflow with helper functions to easily define fixed and random effects as well as diagnostic functions to evaluate the adequacy of the results of the power analysis.
Generalized Least Squares (GLS) estimation of Seemingly Unrelated Regression (SUR) systems on unbalanced panel in the one/two-way cases also taking into account the possibility of cross equation restrictions. Methodological details can be found in Biørn (2004) <doi:10.1016/j.jeconom.2003.10.023> and Platoni, Sckokai, Moro (2012) <doi:10.1080/07474938.2011.607098>.
Reconstruct pedigrees from genotype data, by optimising the likelihood over all possible pedigrees subject to given restrictions. Tailor-made plots facilitate evaluation of the output. This package is part of the pedsuite ecosystem for pedigree analysis. In particular, it imports pedprobr for calculating pedigree likelihoods and forrel for estimating pairwise relatedness.
Deterministic Pena-Yohai initial estimator for robust S estimators of regression. The procedure is described in detail in Pena, D., & Yohai, V. (1999) <doi:10.2307/2670164>.
Perform inference in the secondary analysis setting with linked data potentially containing mismatch errors. Only the linked data file may be accessible and information about the record linkage process may be limited or unavailable. Implements the General Framework for Regression with Mismatched Data developed by Slawski et al. (2023) <doi:10.48550/arXiv.2306.00909>. The framework uses a mixture model for pairs of linked records whose two components reflect distributions conditional on match status, i.e., correct match or mismatch. Inference is based on composite likelihood and the Expectation-Maximization (EM) algorithm. The package currently supports Cox Proportional Hazards Regression (right-censored data only) and Generalized Linear Regression Models (Gaussian, Gamma, Poisson, and Logistic (binary models only)). Information about the underlying record linkage process can be incorporated into the method if available (e.g., assumed overall mismatch rate, safe matches, predictors of match status, or predicted probabilities of correct matches).
This package provides functions to read and write APE-compatible phylogenetic trees in NEXUS and Newick formats, while preserving annotations.
This package provides functions which facilitate harmonization of data from multiple different datasets. Data harmonization involves taking data sources with differing values, creating coding instructions to create a harmonized set of values, then making those data modifications. psHarmonize will assist with data modification once the harmonization instructions are written. Coding instructions are written by the user to create a "harmonization sheet". This sheet catalogs variable names, domains (e.g. clinical, behavioral, outcomes), provides R code instructions for mapping or conversion of data, specifies the variable name in the harmonized data set, and tracks notes. The package will then harmonize the source datasets according to the harmonization sheet to create a harmonized dataset. Once harmonization is finished, the package also has functions that will create descriptive statistics using RMarkdown'. Data Harmonization guidelines have been described by Fortier I, Raina P, Van den Heuvel ER, et al. (2017) <doi:10.1093/ije/dyw075>. Additional details of our R package have been described by Stephen JJ, Carolan P, Krefman AE, et al. (2024) <doi:10.1016/j.patter.2024.101003>.
This package provides tools for estimating model-agnostic prediction intervals using conformal prediction, bootstrapping, and parametric prediction intervals. The package is designed for ease of use, offering intuitive functions for both binned and full conformal prediction methods, as well as parametric interval estimation with diagnostic checks. Currently only working for continuous predictions. For details on the conformal and bin-conditional conformal prediction methods, see Randahl, Williams, and Hegre (2024) <DOI:10.48550/arXiv.2410.14507>.
This package provides Partial least squares Regression for (weighted) beta regression models (Bertrand 2013, <https://ojs-test.apps.ocp.math.cnrs.fr/index.php/J-SFdS/article/view/215>) and k-fold cross-validation of such models using various criteria. It allows for missing data in the explanatory variables. Bootstrap confidence intervals constructions are also available.
Data sets associated with modeling examples in Craig Starbuck's book, "The Fundamentals of People Analytics: With Applications in R".
An implementation of a hybrid method of person-oriented method and perturbation on the model. Pompom is the initials of the two methods. The hybrid method will provide a multivariate intraindividual variability metric (iRAM). The person-oriented method used in this package refers to uSEM (unified structural equation modeling, see Kim et al., 2007, Gates et al., 2010 and Gates et al., 2012 for details). Perturbation on the model was conducted according to impulse response analysis introduced in Lutkepohl (2007). Kim, J., Zhu, W., Chang, L., Bentler, P. M., & Ernst, T. (2007) <doi:10.1002/hbm.20259>. Gates, K. M., Molenaar, P. C. M., Hillary, F. G., Ram, N., & Rovine, M. J. (2010) <doi:10.1016/j.neuroimage.2009.12.117>. Gates, K. M., & Molenaar, P. C. M. (2012) <doi:10.1016/j.neuroimage.2012.06.026>. Lutkepohl, H. (2007, ISBN:3540262393).
Clustering is unsupervised and exploratory in nature. Yet, it can be performed through penalized regression with grouping pursuit. In this package, we provide two algorithms for fitting the penalized regression-based clustering (PRclust) with non-convex grouping penalties, such as group truncated lasso, MCP and SCAD. One algorithm is based on quadratic penalty and difference convex method. Another algorithm is based on difference convex and ADMM, called DC-ADD, which is more efficient. Generalized cross validation and stability based method were provided to select the tuning parameters. Rand index, adjusted Rand index and Jaccard index were provided to estimate the agreement between estimated cluster memberships and the truth.
Jointly segment several ChIP-seq samples to find the peaks which are the same and different across samples. The fast approximate maximum Poisson likelihood algorithm is described in "PeakSegJoint: fast supervised peak detection via joint segmentation of multiple count data samples" <doi:10.48550/arXiv.1506.01286> by TD Hocking and G Bourque.
Cluster analysis via nonparametric density estimation is performed. Operationally, the kernel method is used throughout to estimate the density. Diagnostics methods for evaluating the quality of the clustering are available. The package includes also a routine to estimate the probability density function obtained by the kernel method, given a set of data with arbitrary dimensions.
Miscellaneous small utilities are provided to mitigate issues with messy, inconsistent or high dimensional data and help for preprocessing and preparing analyses.
Mixtures of Poisson Generalized Linear Models for high dimensional count data clustering. The (multivariate) responses can be partitioned into set of blocks. Three different parameterizations of the linear predictor are considered. The models are estimated according to the EM algorithm with an efficient initialization scheme <doi:10.1016/j.csda.2014.07.005>.
This package provides tools for anonymizing sensitive patient and research data. Helps protect privacy while keeping data useful for analysis. Anonymizes IDs, names, dates, locations, and ages while maintaining referential integrity. Methods based on: Sweeney (2002) <doi:10.1142/S0218488502001648>, Dwork et al. (2006) <doi:10.1007/11681878_14>, El Emam et al. (2011) <doi:10.1371/journal.pone.0028071>, Fung et al. (2010) <doi:10.1145/1749603.1749605>.
Speeds up the process of loading raw data from MBA (Multiplex Bead Assay) examinations, performs quality control checks, and automatically normalises the data, preparing it for more advanced, downstream tasks. The main objective of the package is to create a simple environment for a user, who does not necessarily have experience with R language. The package is developed within the project of the same name - PvSTATEM', which is an international project aiming for malaria elimination.
Facilitates the performance of several analyses, including simple and sequential path coefficient analysis, correlation estimate, drawing correlogram, Heatmap, and path diagram. When working with raw data, that includes one or more dependent variables along with one or more independent variables are available, the path coefficient analysis can be conducted. It allows for testing direct effects, which can be a vital indicator in path coefficient analysis. The process of preparing the dataset rule is explained in detail in the vignette file "Path.Analysis_manual.Rmd". You can find this in the folders labelled "data" and "~/inst/extdata". Also see: 1)the lavaan', 2)a sample of sequential path analysis in metan suggested by Olivoto and Lúcio (2020) <doi:10.1111/2041-210X.13384>, 3)the simple PATHSAS macro written in SAS by Cramer et al. (1999) <doi:10.1093/jhered/90.1.260>, and 4)the semPlot() function of OpenMx as initial tools for conducting path coefficient analyses and SEM (Structural Equation Modeling). To gain a comprehensive understanding of path coefficient analysis, both in theory and practice, see a Minitab macro developed by Arminian, A. in the paper by Arminian et al. (2008) <doi:10.1080/15427520802043182>.
This package implements IV-estimator and Bayesian estimator for linear-in-means Spatial Autoregressive (SAR) model (see LeSage, 1997 <doi:10.1177/016001769702000107>; Lee, 2004 <doi:10.1111/j.1468-0262.2004.00558.x>; Bramoullé et al., 2009 <doi:10.1016/j.jeconom.2008.12.021>), while assuming that only a partial information about the network structure is available. Examples are when the adjacency matrix is not fully observed or when only consistent estimation of the network formation model is available (see Boucher and Houndetoungan, 2025 <doi:10.48550/arXiv.2509.08145>).
Applying the global sensitivity analysis workflow to investigate the parameter uncertainty and sensitivity in physiologically based kinetic (PK) models, especially the physiologically based pharmacokinetic/toxicokinetic model with multivariate outputs. The package also provides some functions to check the convergence and sensitivity of model parameters. The workflow was first mentioned in Hsieh et al., (2018) <doi:10.3389/fphar.2018.00588>, then further refined (Hsieh et al., 2020 <doi:10.1016/j.softx.2020.100609>).
It allows the user to determine sample sizes, select probabilistic samples, make estimates of different parameters for the total finite population and in studio domains, using the main design drawings.
Create PX-files from scratch or read and modify existing ones. Includes a function for every PX keyword, making metadata manipulation simple and human-readable.
Recent years have seen an increased interest in novel methods for analyzing quantitative data from experimental psychology. Currently, however, they lack an established and accessible software framework. Many existing implementations provide no guidelines, consisting of small code snippets, or sets of packages. In addition, the use of existing packages often requires advanced programming experience. PredPsych is a user-friendly toolbox based on machine learning predictive algorithms. It comprises of multiple functionalities for multivariate analyses of quantitative behavioral data based on machine learning models.