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Can be used to carry out permutation based gene expression pathway analysis. This work was supported by a National Institute of Allergy and Infectious Disease/National Institutes of Health contract (No. HHSN272200900059C).
This package implements the Bi-objective Lexicographical Classification method and Performance Assessment Ratio at 10% metric for algorithm classification. Constructs matrices representing algorithm performance under multiple criteria, facilitating decision-making in algorithm selection and evaluation. Analyzes and compares algorithm performance based on various metrics to identify the most suitable algorithms for specific tasks. This package includes methods for algorithm classification and evaluation, with examples provided in the documentation. Carvalho (2019) presents a statistical evaluation of algorithmic computational experimentation with infeasible solutions <doi:10.48550/arXiv.1902.00101>. Moreira and Carvalho (2023) analyze power in preprocessing methodologies for datasets with missing values <doi:10.1080/03610918.2023.2234683>.
Implementation of the pattern recognition technique Principal Component Pursuit tailored to environmental health data, as described in Gibson et al (2022) <doi:10.1289/EHP10479>.
Full dynamic system to describe and forecast the spread and the severity of a developing pandemic, based on available data. These data are number of infections, hospitalizations, deaths and recoveries notified each day. The system consists of three transitions, infection-infection, infection-hospital and hospital-death/recovery. The intensities of these transitions are dynamic and estimated using non-parametric local linear estimators. The package can be used to provide forecasts and survival indicators such as the median time spent in hospital and the probability that a patient who has been in hospital for a number of days can leave it alive. Methods are described in Gámiz, Mammen, Martà nez-Miranda, and Nielsen (2024) <doi:10.48550/arXiv.2308.09918> and <doi:10.48550/arXiv.2308.09919>.
Metadata and package cache for CRAN-like repositories. This is a utility package to be used by package management tools that want to take advantage of caching.
This package provides permutation methods for testing in high-dimensional linear models. The tests are often robust against heteroscedasticity and non-normality and usually perform well under anti-sparsity. See Hemerik, Thoresen and Finos (2021) <doi:10.1080/00949655.2020.1836183>.
This package provides a convenient framework for aggregating and disaggregating continuously varying parameters (for example, case fatality ratio, with age) for proper parametrization of lower-resolution compartmental models (for example, with broad age categories) and subsequent upscaling of model outputs to high resolution (for example, as needed when calculating age-sensitive measures like years-life-lost).
It is often advantageous to test a hypothesis more than once in the context of propensity score analysis (Rosenbaum, 2012) <doi:10.1093/biomet/ass032>. The functions in this package facilitate bootstrapping for propensity score analysis (PSA). By default, bootstrapping using two classification tree methods (using rpart and ctree functions), two matching methods (using Matching and MatchIt packages), and stratification with logistic regression. A framework is described for users to implement additional propensity score methods. Visualizations are emphasized for diagnosing balance; exploring the correlation relationships between bootstrap samples and methods; and to summarize results.
This package provides functions for testing phylogenetic niche conservatism, a key prerequisite in community assembly studies. The package integrates global functional trait data across major taxonomic groups and implements methods such as Pagel's Lambda and Blomberg's K to quantify phylogenetic signals in ecological communities. Methods are described in Münkemüller et al. (2012) <doi:10.1111/j.2041-210X.2012.00196.x>.
Handles and formats author information in scientific writing in R Markdown and Quarto'. plume provides easy-to-use and flexible tools for inserting author data in YAML as well as generating author and contribution lists (among others) as strings from tabular data.
Fits successive Lasso models for several blocks of (omics) data with different priorities and takes the predicted values as an offset for the next block. Also offers options to deal with block-wise missingness in multi-omics data.
This package provides a suite of multivariate methods and data visualization tools to implement profile analysis and cross-validation techniques described in Davison & Davenport (2002) <DOI: 10.1037/1082-989X.7.4.468>, Bulut (2013), and other published and unpublished resources. The package includes routines to perform criterion-related profile analysis, profile analysis via multidimensional scaling, moderated profile analysis, profile analysis by group, and a within-person factor model to derive score profiles.
This package provides a clustering approach applicable to every projection method is proposed here. The two-dimensional scatter plot of any projection method can construct a topographic map which displays unapparent data structures by using distance and density information of the data. The generalized U*-matrix renders this visualization in the form of a topographic map, which can be used to automatically define the clusters of high-dimensional data. The whole system is based on Thrun and Ultsch, "Using Projection based Clustering to Find Distance and Density based Clusters in High-Dimensional Data" <DOI:10.1007/s00357-020-09373-2>. Selecting the correct projection method will result in a visualization in which mountains surround each cluster. The number of clusters can be determined by counting valleys on the topographic map. Most projection methods are wrappers for already available methods in R. By contrast, the neighbor retrieval visualizer (NeRV) is based on C++ source code of the dredviz software package, and the Curvilinear Component Analysis (CCA) is translated from MATLAB ('SOM Toolbox 2.0) to R.
Probabilistic factor analysis for spatially-aware dimension reduction across multi-section spatial transcriptomics data with millions of spatial locations. More details can be referred to Wei Liu, et al. (2023) <doi:10.1101/2023.07.11.548486>.
partitionMetric computes a distance between two partitions of a set.
Tests for a comparison of two partially overlapping samples. A comparison of means using the partially overlapping samples t-test: See Derrick, Russ, Toher and White (2017), Test statistics for the comparison of means for two samples which include both paired observations and independent observations, Journal of Modern Applied Statistical Methods, 16(1). A comparison of proportions using the partially overlapping samples z-test: See Derrick, Dobson-Mckittrick, Toher and White (2015), Test statistics for comparing two proportions with partially overlapping samples. Journal of Applied Quantitative Methods, 10(3).
Uses provenance collected by rdtLite package or comparable tool to display information about input files, output files, and exchanged files for a single R script or a series of R scripts.
Automated identification of printed array positions from high content microscopy images and the export of those positions as individual images written to output as multi-layered tiff files.
Streamlines the steps for adding colour scales and associated legends when working with base R graphics, especially for interactive use. Popular palettes are included and pretty legends produced when mapping a large variety of vector classes to a colour scale. An additional helper for adding axes and grid lines complements the base::plot() work flow.
This package provides various functions for retrieving and interpreting information from Pubmed via the API, <https://www.ncbi.nlm.nih.gov/home/develop/api/>.
Download, parses and tidies information from the World Prison Brief project <http://www.prisonstudies.org/>.
This package provides functions to simulate point prevalence studies (PPSs) of healthcare-associated infections (HAIs) and to convert prevalence to incidence in steady state setups. Companion package to the preprint Willrich et al., From prevalence to incidence - a new approach in the hospital setting; <doi:10.1101/554725> , where methods are explained in detail.
User friendly functions for power and sample size analysis at one-way and two-way ANOVA settings take either effect size or delta and sigma as arguments. They are designed for both one-way and two-way ANOVA settings. In addition, a function for plotting power curves is available for power comparison, which can be easily visualized by statisticians and clinical researchers.
The package solves linear system of equations Ax=b by using Preconditioned Conjugate Gradient Algorithm where A is real symmetric positive definite matrix. A suitable preconditioner matrix may be provided by user. This can also be used to minimize quadratic function (x'Ax)/2-bx for unknown x.