For QTL mapping, this package comprises several functions designed to execute diverse tasks, such as simulating or analyzing data, calculating significance thresholds, and visualizing QTL mapping results. The single-QTL or multiple-QTL method, which enables the fitting and comparison of various statistical models, is employed to analyze the data for estimating QTL parameters. The models encompass linear regression, permutation tests, normal mixture models, and truncated normal mixture models. The Gaussian stochastic process is utilized to compute significance thresholds for QTL detection on a genetic linkage map within experimental populations. Two types of data, complete genotyping, and selective genotyping data from various experimental populations, including backcross, F2, recombinant inbred (RI) populations, and advanced intercrossed (AI) populations, are considered in the QTL mapping analysis. For QTL hotspot detection, statistical methods can be developed based on either utilizing individual-level data or summarized data. We have proposed a statistical framework capable of handling both individual-level data and summarized QTL data for QTL hotspot detection. Our statistical framework can overcome the underestimation of thresholds resulting from ignoring the correlation structure among traits. Additionally, it can identify different types of hotspots with minimal computational cost during the detection process. Here, we endeavor to furnish the R codes for our QTL mapping and hotspot detection methods, intended for general use in genes, genomics, and genetics studies. The QTL mapping methods for the complete and selective genotyping designs are based on the multiple interval mapping (MIM) model proposed by Kao, C.-H. , Z.-B. Zeng and R. D. Teasdale (1999) <doi: 10.1534/genetics.103.021642> and H.-I Lee, H.-A. Ho and C.-H. Kao (2014) <doi: 10.1534/genetics.114.168385>, respectively. The QTL hotspot detection analysis is based on the method by Wu, P.-Y., M.-.H. Yang, and C.-H. Kao (2021) <doi: 10.1093/g3journal/jkab056>.

The QRI_func() function performs quantile regression analysis using age and sex as predictors to calculate the Quantile Regression Index (QRI) score for each individualâ s regional brain imaging metrics and then averages across the regional scores to generate an average tissue specific score for each subject. The QRI_plot() is used to plot QRI and generate the normative curves for individual measurements.

Finding hidden clusters in structured data can be hindered by the presence of masking variables. If not detected, masking variables are used to calculate the overall similarities between units, and therefore the cluster attribution is more imprecise. The algorithm q-vars implements an optimization method to find the variables that most separate units between clusters. In this way, masking variables can be discarded from the data frame and the clustering is more accurate. Tests can be found in Benati et al.(2017) <doi:10.1080/01605682.2017.1398206>.

Compile R functions annotated with type and shape declarations for extremely fast performance and robust runtime type checking. Supports both just-in-time (JIT) and ahead-of-time (AOT) compilation. Compilation is performed by lowering R code to Fortran.

Fuel economy, size, performance, and price data for cars in Qatar in 2025. Mirrors many of the columns in mtcars, but uses (1) non-US-centric makes and models, (2) 2025 prices, and (3) metric measurements, making it more appropriate for use as an example dataset outside the United States. For more details see Musgrave (2025) <doi:10.1080/15512169.2025.2572320>.

This package provides seamless access to the QGIS (<https://qgis.org>) processing toolbox using the standalone qgis_process command-line utility. Both native and third-party (plugin) processing providers are supported. Beside referring data sources from file, also common objects from sf', terra and stars are supported. The native processing algorithms are documented by QGIS.org (2024) <https://docs.qgis.org/latest/en/docs/user_manual/processing_algs/>.

Basic functions for building parsers, with an application to PC-AXIS format files.

The modeling and prediction of graph-associated time series(GATS) based on continuous time quantum walk. This software is mainly used for feature extraction, modeling, prediction and result evaluation of GATS, including continuous time quantum walk simulation, feature selection, regression analysis, time series prediction, and series fit calculation. A paper is attached to the package for reference.

This package provides a sigmoidal quantile function estimator based on a newly defined generalized expectile function. The generalized sigmoidal quantile function can estimate quantiles beyond the range of the data, which is important for certain applications given smaller sample sizes. The package is based on the method introduced in Hutson (2024) <doi:10.1080/03610918.2022.2032161>.

This function produces both the numerical and graphical summaries of the QTL hotspot detection in the genomes that are available on the worldwide web including the flanking markers of QTLs.

Quantile correlation-sure independence screening (QC-SIS) and composite quantile correlation-sure independence screening (CQC-SIS) for ultrahigh-dimensional data.

This package provides three Quarto website templates as an R project, which are commonly used by academics. Templates for personal websites and course/workshop websites are included, as well as a template with minimal content for customization.

Upload raster data and easily create interactive quantitative risk analysis QRA visualizations. Select from numerous color palettes, base-maps, and different configurations.

Construct message-passing style objects with types and features. Q7 types uses composition instead of inheritance in creating derived types, allowing defining any code segment as feature and associating any feature to any object. Compared to R6, Q7 is simpler and more flexible, and is more friendly in syntax.

Conduct multiple quantitative trait loci (QTL) and QTL-by-environment interaction (QEI) mapping via ordinary or compressed variance component mixed models with random- or fixed QTL/QEI effects. First, each position on the genome is detected in order to obtain a negative logarithm P-value curve against genome position. Then, all the peaks on each effect (additive or dominant) curve or on each locus curve are viewed as potential main-effect QTLs and QEIs, all their effects are included in a multi-locus model, their effects are estimated by both least angle regression and empirical Bayes (or adaptive lasso) in backcross and F2 populations, and true QTLs and QEIs are identified by likelihood radio test. See Zhou et al. (2022) <doi:10.1093/bib/bbab596> and Wen et al. (2018) <doi:10.1093/bib/bby058>.

Property based testing, inspired by the original QuickCheck'. This package builds on the property based testing framework provided by hedgehog and is designed to seamlessly integrate with testthat'.

This package provides a collection of text analysis dictionaries and word lists for use with the qdap package.

This package implements a suite of tools for outlier detection and treatment in data mining. It includes univariate methods (Z-score, Interquartile Range), multivariate detection using Mahalanobis distance, and density-based detection (Local Outlier Factor) via the dbscan package. It also provides functions for visualization using ggplot2 and data cleaning via Winsorization.

Presents an explanatory animation of normal quantile-quantile plots based on a water-filling analogy. The animation presents a normal QQ plot as the parametric plot of the water levels in vases defined by two distributions. The distributions decorate the axes in the normal QQ plot and are optionally shown as vases adjacent to the plot. The package draws QQ plots for several distributions, either as samples or continuous functions.

Compute various quantitative genetics parameters from a Generalised Linear Mixed Model (GLMM) estimates. Especially, it yields the observed phenotypic mean, phenotypic variance and additive genetic variance.

Extensions of ggplot2 Q-Q plot functionalities.

This package provides a re-implementation of quantile kriging. Quantile kriging was described by Plumlee and Tuo (2014) <doi:10.1080/00401706.2013.860919>. With computational savings when dealing with replication from the recent paper by Binois, Gramacy, and Ludovski (2018) <doi:10.1080/10618600.2018.1458625> it is now possible to apply quantile kriging to a wider class of problems. In addition to fitting the model, other useful tools are provided such as the ability to automatically perform leave-one-out cross validation.

Select optimal functional regression or dichotomized quantile predictors for survival/logistic/numeric outcome and perform optimistic bias correction for any optimally dichotomized numeric predictor(s), as in Yi, et. al. (2023) <doi:10.1016/j.labinv.2023.100158>.

This package provides methods for estimation of mean- and quantile-optimal treatment regimes from censored data. Specifically, we have developed distinct functions for three types of right censoring for static treatment using quantile criterion: (1) independent/random censoring, (2) treatment-dependent random censoring, and (3) covariates-dependent random censoring. It also includes a function to estimate quantile-optimal dynamic treatment regimes for independent censored data. Finally, this package also includes a simulation data generative model of a dynamic treatment experiment proposed in literature.