This package provides a general-purpose optimisation engine that supports i) Monte Carlo optimisation with Metropolis criterion [Metropolis et al. (1953) <doi:10.1063/1.1699114>, Hastings (1970) <doi:10.1093/biomet/57.1.97>] and Acceptance Ratio Simulated Annealing [Kirkpatrick et al. (1983) <doi:10.1126/science.220.4598.671>, Ä erný (1985) <doi:10.1007/BF00940812>] on multiple cores, and ii) Acceptance Ratio Replica Exchange Monte Carlo Optimisation. In each case, the system pseudo-temperature is dynamically adjusted such that the observed acceptance ratio is kept near to the desired (fixed or changing) acceptance ratio.

An implementation to compute an optimal dose escalation rule using deep reinforcement learning in phase I oncology trials (Matsuura et al. (2023) <doi:10.1080/10543406.2023.2170402>). The dose escalation rule can directly optimize the percentages of correct selection (PCS) of the maximum tolerated dose (MTD).

This package provides a framework for the measurement and partitioning of the (similarity-sensitive) biodiversity of a metacommunity and its constituent subcommunities. Richard Reeve, et al. (2016) <arXiv:1404.6520v3>.

This package provides the Book-Crossing Dataset for the package recommenderlab.

Set of classes and methods to read data and metadata documents exchanged through the Statistical Data and Metadata Exchange (SDMX) framework, currently focusing on the SDMX XML standard format (SDMX-ML).

Adaptation of the Matlab tsEVA toolbox developed by Lorenzo Mentaschi available here: <https://github.com/menta78/tsEva>. It contains an implementation of the Transformed-Stationary (TS) methodology for non-stationary extreme value Analysis (EVA) as described in Mentaschi et al. (2016) <doi:10.5194/hess-20-3527-2016>. In synthesis this approach consists in: (i) transforming a non-stationary time series into a stationary one to which the stationary extreme value theory can be applied; and (ii) reverse-transforming the result into a non-stationary extreme value distribution. RtsEva offers several options for trend estimation (mean, extremes, seasonal) and contains multiple plotting functions displaying different aspects of the non-stationarity of extremes.

Color palettes from famous artists and paintings.

The Bayesian modelling of relative sea-level data using a comprehensive approach that incorporates various statistical models within a unifying framework. Details regarding each statistical models; linear regression (Ashe et al 2019) <doi:10.1016/j.quascirev.2018.10.032>, change point models (Cahill et al 2015) <doi:10.1088/1748-9326/10/8/084002>, integrated Gaussian process models (Cahill et al 2015) <doi:10.1214/15-AOAS824>, temporal splines (Upton et al 2023) <arXiv:2301.09556>, spatio-temporal splines (Upton et al 2023) <arXiv:2301.09556> and generalised additive models (Upton et al 2023) <arXiv:2301.09556>. This package facilitates data loading, model fitting and result summarisation. Notably, it accommodates the inherent measurement errors found in relative sea-level data across multiple dimensions, allowing for their inclusion in the statistical models.

Download large sections of GenBank <https://www.ncbi.nlm.nih.gov/genbank/> and generate a local SQL-based database. A user can then query this database using restez functions or through rentrez <https://CRAN.R-project.org/package=rentrez> wrappers.

Convenience functions to make some common tasks with right-to-left string printing easier, more convenient and with no need to remember long Unicode characters. Specifically helpful for right-to-left languages such as Arabic, Persian and Hebrew.

Data sets, and functions for simulating and fitting nonlinear time series with minification and nonparametric models.

This package provides a GUI front-end for ggplot2 supports Kaplan-Meier plot, histogram, Q-Q plot, box plot, errorbar plot, scatter plot, line chart, pie chart, bar chart, contour plot, and distribution plot.

Easy installation, loading, and control of packages for redistricting data downloading, spatial data processing, simulation, analysis, and visualization. This package makes it easy to install and load multiple redistverse packages at once. The redistverse is developed and maintained by the Algorithm-Assisted Redistricting Methodology (ALARM) Project. For more details see <https://alarm-redist.org>.

This package provides R-squared values and standardized regression coefficients for linear models applied to multiply imputed datasets as obtained by mice'. Confidence intervals, zero-order correlations, and alternative adjusted R-squared estimates are also available. The methods are described in Van Ginkel and Karch (2024) <doi:10.1111/bmsp.12344> and in Van Ginkel (2020) <doi:10.1007/s11336-020-09696-4>.

Downloads spatial data from spatiotemporal asset catalogs ('STAC'), computes standard spectral indices from the Awesome Spectral Indices project (Montero et al. (2023) <doi:10.1038/s41597-023-02096-0>) against raster data, and glues the outputs together into predictor bricks. Methods focus on interoperability with the broader spatial ecosystem; function arguments and outputs use classes from sf and terra', and data downloading functions support complex CQL2 queries using rstac'.

Allows the user to learn Bayesian networks from datasets containing thousands of variables. It focuses on score-based learning, mainly the BIC and the BDeu score functions. It provides state-of-the-art algorithms for the following tasks: (1) parent set identification - Mauro Scanagatta (2015) <http://papers.nips.cc/paper/5803-learning-bayesian-networks-with-thousands-of-variables>; (2) general structure optimization - Mauro Scanagatta (2018) <doi:10.1007/s10994-018-5701-9>, Mauro Scanagatta (2018) <http://proceedings.mlr.press/v73/scanagatta17a.html>; (3) bounded treewidth structure optimization - Mauro Scanagatta (2016) <http://papers.nips.cc/paper/6232-learning-treewidth-bounded-bayesian-networks-with-thousands-of-variables>; (4) structure learning on incomplete data sets - Mauro Scanagatta (2018) <doi:10.1016/j.ijar.2018.02.004>. Distributed under the LGPL-3 by IDSIA.

Utility functions to retrieve data from the UK National River Flow Archive (<https://nrfa.ceh.ac.uk/>, terms and conditions: <https://nrfa.ceh.ac.uk/help/costs-terms-and-conditions>). The package contains R wrappers to the UK NRFA data temporary-API. There are functions to retrieve stations falling in a bounding box, to generate a map and extracting time series and general information. The package is fully described in Vitolo et al (2016) "rnrfa: An R package to Retrieve, Filter and Visualize Data from the UK National River Flow Archive" <https://journal.r-project.org/archive/2016/RJ-2016-036/RJ-2016-036.pdf>.

This package provides a random-effects stochastic model that allows quick detection of clonal dominance events from clonal tracking data collected in gene therapy studies. Starting from the Ito-type equation describing the dynamics of cells duplication, death and differentiation at clonal level, we first considered its local linear approximation as the base model. The parameters of the base model, which are inferred using a maximum likelihood approach, are assumed to be shared across the clones. Although this assumption makes inference easier, in some cases it can be too restrictive and does not take into account possible scenarios of clonal dominance. Therefore we extended the base model by introducing random effects for the clones. In this extended formulation the dynamic parameters are estimated using a tailor-made expectation maximization algorithm. Further details on the methods can be found in L. Del Core et al., (2022) <doi:10.1101/2022.05.31.494100>.

Collection of functions to evaluate sequences, decode hidden states and estimate parameters from a single or multiple sequences of a discrete time Hidden Markov Model. The observed values can be modeled by a multinomial distribution for categorical/labeled emissions, a mixture of Gaussians for continuous data and also a mixture of Poissons for discrete values. It includes functions for random initialization, simulation, backward or forward sequence evaluation, Viterbi or forward-backward decoding and parameter estimation using an Expectation-Maximization approach.

Extract text or metadata from over a thousand file types, using Apache Tika <https://tika.apache.org/>. Get either plain text or structured XHTML content.

This package provides subsets with reference semantics, i.e. subsets which automatically reflect changes in the original object, and which optionally update the original object when they are changed.

Facilitates making a connection to the Revenera API and executing various queries. You can use it to get event data and metadata. The Revenera documentation is available at <https://rui-api.redoc.ly/>. This package is not supported by Flexera (owner of the software).

This package provides a function to plot a regression nomogram of regression objects. Covariate distributions are superimposed on nomogram scales and the plot can be animated to allow on-the-fly changes to distribution representation and to enable outcome calculation.

R Commander plug-in to demonstrate various actuarial and financial risks. It includes valuation of bonds and stocks, portfolio optimization, classical ruin theory, demography and epidemic.