Utilities for single nucleotide polymorphism (SNP) based kinship analysis testing and evaluation. The skater package contains functions for importing, parsing, and analyzing pedigree data, performing relationship degree inference, benchmarking relationship degree classification, and summarizing identity by descent (IBD) segment data. Package functions and methods are described in Turner et al. (2021) "skater: An R package for SNP-based Kinship Analysis, Testing, and Evaluation" <doi:10.1101/2021.07.21.453083>.

SOHPIE (pronounced as SOFIE) is a novel pseudo-value regression approach for differential co-abundance network analysis of microbiome data, which can include additional clinical covariate in the model. The full methodological details can be found in Ahn S and Datta S (2023) <arXiv:2303.13702v1>.

Sparse principal component analysis (SPCA) attempts to find sparse weight vectors (loadings), i.e., a weight vector with only a few active (nonzero) values. This approach provides better interpretability for the principal components in high-dimensional data settings. This is, because the principal components are formed as a linear combination of only a few of the original variables. This package provides efficient routines to compute SPCA. Specifically, a variable projection solver is used to compute the sparse solution. In addition, a fast randomized accelerated SPCA routine and a robust SPCA routine is provided. Robust SPCA allows to capture grossly corrupted entries in the data. The methods are discussed in detail by N. Benjamin Erichson et al. (2018) <arXiv:1804.00341>.

Analyzing soil food webs or any food web measured at equilibrium. The package calculates carbon and nitrogen fluxes and stability properties using methods described by Hunt et al. (1987) <doi:10.1007/BF00260580>, de Ruiter et al. (1995) <doi:10.1126/science.269.5228.1257>, Holtkamp et al. (2011) <doi:10.1016/j.soilbio.2010.10.004>, and Buchkowski and Lindo (2021) <doi:10.1111/1365-2435.13706>. The package can also manipulate the structure of the food web as well as simulate food webs away from equilibrium and run decomposition experiments.

This package provides functions and data sets inspired by data sharpening - data perturbation to achieve improved performance in nonparametric estimation, as described in Choi, E., Hall, P. and Rousson, V. (2000). Capabilities for enhanced local linear regression function and derivative estimation are included, as well as an asymptotically correct iterated data sharpening estimator for any degree of local polynomial regression estimation. A cross-validation-based bandwidth selector is included which, in concert with the iterated sharpener, will often provide superior performance, according to a median integrated squared error criterion. Sample data sets are provided to illustrate function usage.

This statistical method uses the nearest neighbor algorithm to estimate absolute distances between single cells based on a chosen constellation of surface proteins, with these distances being a measure of the similarity between the two cells being compared. Based on Sen, N., Mukherjee, G., and Arvin, A.M. (2015) <DOI:10.1016/j.ymeth.2015.07.008>.

The main function is icweib(), which fits a stratified Weibull proportional hazards model for left censored, right censored, interval censored, and non-censored survival data. We parameterize the Weibull regression model so that it allows a stratum-specific baseline hazard function, but where the effects of other covariates are assumed to be constant across strata. Please refer to Xiangdong Gu, David Shapiro, Michael D. Hughes and Raji Balasubramanian (2014) <doi:10.32614/RJ-2014-003> for more details.

The sparse principal component regression is computed. The regularization parameters are optimized by cross-validation.

Training and validation of a custom (or data-driven) Structural Equation Models using Deep Neural Networks or Machine Learning algorithms, which extend the fitting procedures of the SEMgraph R package <doi:10.32614/CRAN.package.SEMgraph>.

Efficient regression analysis under general two-phase sampling, where Phase I includes error-prone data and Phase II contains validated data on a subset.

This package provides nonparametric Steinian shrinkage estimators of the covariance matrix that are suitable in high dimensional settings, that is when the number of variables is larger than the sample size.

This package provides a spatio-dynamic modelling package that focuses on three characteristic wetland plant communities in a semiarid Mediterranean wetland in response to hydrological pressures from the catchment. The package includes the data on watershed hydrological pressure and the initial raster maps of plant communities but also allows for random initial distribution of plant communities. For more detailed info see: Martinez-Lopez et al. (2015) <doi:10.1016/j.ecolmodel.2014.11.024>.

This package provides a fast implementation with additional experimental features for testing, monitoring and dating structural changes in (linear) regression models. strucchangeRcpp features tests/methods from the generalized fluctuation test framework as well as from the F test (Chow test) framework. This includes methods to fit, plot and test fluctuation processes (e.g. cumulative/moving sum, recursive/moving estimates) and F statistics, respectively. These methods are described in Zeileis et al. (2002) <doi:10.18637/jss.v007.i02>. Finally, the breakpoints in regression models with structural changes can be estimated together with confidence intervals, and their magnitude as well as the model fit can be evaluated using a variety of statistical measures.

This package provides a collection of functions for preparing data and fitting Bayesian count spatial regression models, with a specific focus on the Gamma-Count (GC) model. The GC model is well-suited for modeling dispersed count data, including under-dispersed or over-dispersed counts, or counts with equivalent dispersion, using Integrated Nested Laplace Approximations (INLA). The package includes functions for generating data from the GC model, as well as spatially correlated versions of the model. See Nadifar, Baghishani, Fallah (2023) <doi:10.1007/s13253-023-00550-5>.

This package provides predictive accuracy tools to evaluate time-to-event survival models. This includes calculating the concordance probability estimate that incorporates the follow-up time for a particular study developed by Devlin, Gonen, Heller (2020)<doi:10.1007/s10985-020-09503-3>. It also evaluates the concordance probability estimate for nested Cox proportional hazards models using a projection-based approach by Heller and Devlin (under review).

This package provides a statistical learning method to simultaneously predict a range of target phenotypes using codified and natural language processing (NLP)-derived Electronic Health Record (EHR) data. See Ahuja et al (2020) JAMIA <doi:10.1093/jamia/ocaa079> for details.

This package provides a comprehensive framework for descriptive statistics and regression analysis that produces publication-ready tables and forest plots. Provides a unified interface from descriptive statistics through multivariable modeling, with support for linear models, generalized linear models, Cox proportional hazards, and mixed-effects models. Also includes univariable screening, multivariate regression, model comparison, and export to multiple formats including PDF, DOCX, PPTX, LaTeX', HTML, and RTF. Built on data.table for computational efficiency.

Algorithms of nonparametric sequential test and online change-point detection for streams of univariate (sub-)Gaussian, binary, and bounded random variables, introduced in following publications - Shin et al. (2024) <doi:10.48550/arXiv.2203.03532>, Shin et al. (2021) <doi:10.48550/arXiv.2010.08082>.

An implementation of local and global statistical complexity measures (aka Information Theory Quantifiers, ITQ) for time series analysis based on ordinal statistics (Bandt and Pompe (2002) <DOI:10.1103/PhysRevLett.88.174102>). Several distance measures that operate on ordinal pattern distributions, auxiliary functions for ordinal pattern analysis, and generating functions for stochastic and deterministic-chaotic processes for ITQ testing are provided.

This package provides functions for converting and processing network data from a SpatialLinesDataFrame -Class object to an igraph'-Class object.

The implementation to perform the geometric spatial point analysis developed in Hernández & Solàs (2022) <doi:10.1007/s00180-022-01244-1>. It estimates the geometric goodness-of-fit index for a set of variables against a response one based on the sf package. The package has methods to print and plot the results.

This package provides a simulator for reticulate evolution under a birth-death-hybridization process. Here the birth-death process is extended to consider reticulate Evolution by allowing hybridization events to occur. The general purpose simulator allows the modeling of three different reticulate patterns: lineage generative hybridization, lineage neutral hybridization, and lineage degenerative hybridization. Users can also specify hybridization events to be dependent on a trait value or genetic distance. We also extend some phylogenetic tree utility and plotting functions for networks. We allow two different stopping conditions: simulated to a fixed time or number of taxa. When simulating to a fixed number of taxa, the user can simulate under the Generalized Sampling Approach that properly simulates phylogenies when assuming a uniform prior on the root age.

Compute the frequency distribution of a search term in a series of texts. For example, Arthur Conan Doyle wrote a total of 60 Sherlock Holmes stories, comprised of 54 short stories and 4 longer novels. I wanted to test my own subjective impression that, in many of the stories, Sherlock Holmes popularity was used as bait to induce the reader to read a story that is essentially not primarily a Sherlock Holmes story. I used the term "Holmes" as a search pattern, since Watson would frequently address him by name, or use his name to describe something that he was doing. My hypothesis is that the frequency distribution of the search pattern "Holmes" is a good proxy for the degree to which a story is or is not truly a Sherlock Holmes story. The results are presented in a manuscript that is available as a vignette and online at <https://barryzee.github.io/Concordance/index.html>.

Estimation, scoring, and plotting functions for the semi-parametric factor model proposed by Liu & Wang (2022) <doi:10.1007/s11336-021-09832-8> and Liu & Wang (2023) <arXiv:2303.10079>. Both the conditional densities of observed responses given the latent factors and the joint density of latent factors are estimated non-parametrically. Functional parameters are approximated by smoothing splines, whose coefficients are estimated by penalized maximum likelihood using an expectation-maximization (EM) algorithm. E- and M-steps can be parallelized on multi-thread computing platforms that support OpenMP'. Both continuous and unordered categorical response variables are supported.