We focus on the diagnostic ability assessment of medical tests when the outcome of interest is the status (alive or dead) of the subjects at a certain time-point t. This binary status is determined by right-censored times to event and it is unknown for those subjects censored before t. Here we provide three methods (unknown status exclusion, imputation of censored times and using time-dependent ROC curves) to evaluate the diagnostic ability of binary and continuous tests in this context. Two references for the methods used here are Skaltsa et al. (2010) <doi:10.1002/bimj.200900294> and Heagerty et al. (2000) <doi:10.1111/j.0006-341x.2000.00337.x>.

Probability mass (d), distribution (p), quantile (q), and random number generating (r and rt) functions for the time-varying right-truncated geometric (tvgeom) distribution. Also provided are functions to calculate the first and second central moments of the distribution. The tvgeom distribution is similar to the geometric distribution, but the probability of success is allowed to vary at each time step, and there are a limited number of trials. This distribution is essentially a Markov chain, and it is useful for modeling Markov chain systems with a set number of time steps.

The modern database TileDB introduces a powerful on-disk format for storing and accessing any complex data based on multi-dimensional arrays. It supports dense and sparse arrays, dataframes and key-values stores, cloud storage ('S3', GCS', Azure'), chunked arrays, multiple compression, encryption and checksum filters, uses a fully multi-threaded implementation, supports parallel I/O, data versioning ('time travel'), metadata and groups. It is implemented as an embeddable cross-platform C++ library with APIs from several languages, and integrations. This package provides the R support.

Regression models for temporal process responses with time-varying coefficient.

This package provides a framework to download, parse, and store text datasets on the disk and load them when needed. Includes various sentiment lexicons and labeled text data sets for classification and analysis.

Obtain population density and body size structure, using video material or image sequences as input. Functions assist in the creation of image sequences from videos, background detection and subtraction, particle identification and tracking. An artificial neural network can be trained for noise filtering. The goal is to supply accurate estimates of population size, structure and/or individual behavior, for use in evolutionary and ecological studies.

This package provides a problem solving environment (PSE) for fitting separable nonlinear models to measurements arising in physics and chemistry experiments, as described by Mullen & van Stokkum (2007) <doi:10.18637/jss.v018.i03> for its use in fitting time resolved spectroscopy data, and as described by Laptenok et al. (2007) <doi:10.18637/jss.v018.i08> for its use in fitting Fluorescence Lifetime Imaging Microscopy (FLIM) data, in the study of Förster Resonance Energy Transfer (FRET). `TIMP` also serves as the computation backend for the `GloTarAn` software, a graphical user interface for the package, as described in Snellenburg et al. (2012) <doi:10.18637/jss.v049.i03>.

This package provides a coherent interface for evaluating models fit with the trending package. This package is part of the RECON (<https://www.repidemicsconsortium.org/>) toolkit for outbreak analysis.

Analysis and visualization of data from temporal sensory methods, including for temporal check-all-that-apply (TCATA) and temporal dominance of sensations (TDS). Methods are mainly from manuscripts by Castura, J.C., Antúnez, L., Giménez, A., and Ares, G. (2016) <doi:10.1016/j.foodqual.2015.06.017>, Castura, Baker, and Ross (2016) <doi:10.1016/j.foodqual.2016.06.011>, and Pineau et al. (2009) <doi:10.1016/j.foodqual.2009.04.005>.

This package implements methods to fit Virtual Twins models (Foster et al. (2011) <doi:10.1002/sim.4322>) for identifying subgroups with differential effects in the context of clinical trials while controlling the probability of falsely detecting a differential effect when the conditional average treatment effect is uniform across the study population using parameter selection methods proposed in Wolf et al. (2022) <doi:10.1177/17407745221095855>.

This package implements the Temporal Forest algorithm for feature selection in high-dimensional longitudinal data. The method combines time-aware network construction via weighted gene co-expression network analysis (WGCNA), module-based feature screening, and stability selection using tree-based models. This package provides tools for reproducible longitudinal analysis, closely following the methodology described in Shao, Moore, and Ramirez (2025) <https://github.com/SisiShao/TemporalForest>.

Create structured, formatted HTML tables of in a flexible and convenient way.

This package provides tools to download data series from Banco de España ('BdE') on tibble format. Banco de España is the national central bank and, within the framework of the Single Supervisory Mechanism ('SSM'), the supervisor of the Spanish banking system along with the European Central Bank. This package is in no way sponsored endorsed or administered by Banco de España'.

This package provides a suite of descriptive and inferential methods designed to evaluate one or more biomarkers for their ability to guide patient treatment recommendations. Package includes functions to assess the calibration of risk models; and plot, evaluate, and compare markers. Please see the reference Janes H, Brown MD, Huang Y, et al. (2014) <doi:10.1515/ijb-2012-0052> for further details.

This package implements methods for selecting the number of factors in Poisson factor models, with a primary focus on Thinning Cross-Validation (TCV). The TCV method is based on the data thinning technique, which probabilistically partitions each count observation into training and test sets while preserving the underlying factor structure. The Poisson factor model is then fit on the training set, and model selection is performed by comparing predictive performance on the test set. This toolkit is designed for researchers working with high-dimensional count data in fields such as genomics, text mining, and social sciences. The data thinning methodology is detailed in Dharamshi et al. (2025) <doi:10.1080/01621459.2024.2353948> and Wang et al. (2025) <doi:10.1080/01621459.2025.2546577>.

This package provides a traceability focused tool created to simplify the data manipulation necessary to create clinical summaries.

This package provides a system for personalized exercise plan recommendations for T2D (Type 2 Diabetes) patients based on the primary outcome of HbA1c (Glycated Hemoglobin). You provide the individual's information, and T2DFitTailor details the exercise plan and predicts the intervention's effectiveness.

This package provides functions for estimation of wood volumes, number of logs, diameters along the stem and heights at which certain diameters occur, based on taper functions and other parameters. References: McTague, J. P., & Weiskittel, A. (2021). <doi:10.1139/cjfr-2020-0326>.

R spatial objects for Tilegrams. Tilegrams are tiled maps where the region size is proportional to the certain characteristics of the dataset.

The tdROC package facilitates the estimation of time-dependent ROC (Receiver Operating Characteristic) curves and the Area Under the time-dependent ROC Curve (AUC) in the context of survival data, accommodating scenarios with right censored data and the option to account for competing risks. In addition to the ROC/AUC estimation, the package also estimates time-dependent Brier score and survival difference. Confidence intervals of various estimated quantities can be obtained from bootstrap. The package also offers plotting functions for visualizing time-dependent ROC curves.

Pure R implementation of Apache Thrift. This library doesn't require any code generation. To learn more about Thrift go to <https://thrift.apache.org>.

Changepoint detection algorithms for R are widespread but have different interfaces and reporting conventions. This makes the comparative analysis of results difficult. We solve this problem by providing a tidy, unified interface for several different changepoint detection algorithms. We also provide consistent numerical and graphical reporting leveraging the broom and ggplot2 packages.

It includes functions like tropical addition, tropical multiplication for vectors and matrices. In tropical algebra, the tropical sum of two numbers is their minimum and the tropical product of two numbers is their ordinary sum. For more information see also I. Simon (1988) Recognizable sets with multiplicities in the tropical semi ring: Volume 324 Lecture Notes I Computer Science, pages 107-120 <doi: 10.1007/BFb0017135>.

Implementation of the classic Genz algorithm and a novel tile-low-rank algorithm for computing relatively high-dimensional multivariate normal (MVN) and Student-t (MVT) probabilities. References used for this package: Foley, James, Andries van Dam, Steven Feiner, and John Hughes. "Computer Graphics: Principle and Practice". Addison-Wesley Publishing Company. Reading, Massachusetts (1987, ISBN:0-201-84840-6 1); Genz, A., "Numerical computation of multivariate normal probabilities," Journal of Computational and Graphical Statistics, 1, 141-149 (1992) <doi:10.1080/10618600.1992.10477010>; Cao, J., Genton, M. G., Keyes, D. E., & Turkiyyah, G. M. "Exploiting Low Rank Covariance Structures for Computing High-Dimensional Normal and Student- t Probabilities," Statistics and Computing, 31.1, 1-16 (2021) <doi:10.1007/s11222-020-09978-y>; Cao, J., Genton, M. G., Keyes, D. E., & Turkiyyah, G. M. "tlrmvnmvt: Computing High-Dimensional Multivariate Normal and Student-t Probabilities with Low-Rank Methods in R," Journal of Statistical Software, 101.4, 1-25 (2022) <doi:10.18637/jss.v101.i04>.