Suite of tropical geometric tools for use in machine learning applications. These methods may be summarized in the following references: Yoshida, et al. (2022) <doi:10.2140/astat.2023.14.37>, Barnhill et al. (2023) <doi:10.48550/arXiv.2303.02539>, Barnhill and Yoshida (2023) <doi:10.3390/math11153433>, Aliatimis et al. (2023) <doi:10.1007/s11538-024-01327-8>, Yoshida et al. (2022) <doi:10.1109/TCBB.2024.3420815>, and Yoshida et al. (2019) <doi:10.1007/s11538-018-0493-4>.

The goal of tidyplate is to help researchers convert different types of microplates into tibbles which can be used in data analysis. It accepts xlsx and csv files formatted in a specific way as input. It supports all types of standard microplate formats such as 6-well, 12-well, 24-well, 48-well, 96-well, 384-well, and, 1536-well plates.

Uses read counts for biallelic single nucleotide polymorphisms (SNPs) to compare the likelihoods for the observed read counts given that a sample is either diploid or triploid. It allows parameters to be specified to account for sequencing error rates and allelic bias. For details of the algorithm, please see Delomas (2019) <doi:10.1111/1755-0998.13073>.

This package provides a standardized workflow to reconstruct spatial configurations of altitude-bounded biogeographic systems over time. For example, tabs can model how island archipelagos expand or contract with changing sea levels or how alpine biomes shift in response to tree line movements. It provides functionality to account for various geophysical processes such as crustal deformation and other tectonic changes, allowing for a more accurate representation of biogeographic system dynamics. For more information see De Groeve et al. (2025) <doi:10.21425/fob.18.151677>.

Use SQL SELECT statements to query R data frames.

To visualize the gene structure with multiple isoforms better, I developed this package to draw different transcript structures easily.

Innovative Trend Analysis is a graphical method to examine the trends in time series data. Sequential Mann-Kendall test uses the intersection of prograde and retrograde series to indicate the possible change point in time series data. Distribution free cumulative sum charts indicate location and significance of the change point in time series. Zekai, S. (2011). <doi:10.1061/(ASCE)HE.1943-5584.0000556>. Grayson, R. B. et al. (1996). Hydrological Recipes: Estimation Techniques in Australian Hydrology. Cooperative Research Centre for Catchment Hydrology, Australia, p. 125. Sneyers, S. (1990). On the statistical analysis of series of observations. Technical note no 5 143, WMO No 725 415. Secretariat of the World Meteorological Organization, Geneva, 192 pp.

Tidy standardized mean differences ('SMDs'). tidysmd uses the smd package to calculate standardized mean differences for variables in a data frame, returning the results in a tidy format.

Different multiple testing procedures for correlation tests are implemented. These procedures were shown to theoretically control asymptotically the Family Wise Error Rate (Roux (2018) <https://tel.archives-ouvertes.fr/tel-01971574v1>) or the False Discovery Rate (Cai & Liu (2016) <doi:10.1080/01621459.2014.999157>). The package gather four test statistics used in correlation testing, four FWER procedures with either single step or stepdown versions, and four FDR procedures.

This package provides methods and feature set definitions for feature or gene set enrichment analysis in transcriptional and metabolic profiling data. Package includes tests for enrichment based on ranked lists of features, functions for visualisation and multivariate functional analysis. See Zyla et al (2019) <doi:10.1093/bioinformatics/btz447>.

This package provides a tool to create and style HTML tables with CSS. These can be exported and used in any application that accepts HTML (e.g. shiny', rmarkdown', PowerPoint'). It also provides functions to create CSS files (which also work with shiny).

Uses the Distorted Wave Born Approximation (DWBA) to compute the acoustic backward scattering, the geometry of the object is formed by a volumetric mesh, composed of tetrahedrons. This computation is done efficiently through an analytical 3D integration that allows for a solution which is expressed in terms of elementary functions for each tetrahedron. It is important to note that this method is only valid for objects whose acoustic properties, such as density and sound speed, do not vary significantly compared to the surrounding medium. (See Lavia, Cascallares and Gonzalez, J. D. (2023). TetraScatt model: Born approximation for the estimation of acoustic dispersion of fluid-like objects of arbitrary geometries. arXiv preprint <arXiv:2312.16721>).

An implementation that combines trait data and a phylogenetic tree (or trees) into a single object of class treedata.table'. The resulting object can be easily manipulated to simultaneously change the trait- and tree-level sampling. Currently implemented functions allow users to use a data.table syntax when performing operations on the trait dataset within the treedata.table object. For more details see Roman-Palacios et al. (2021) <doi:10.7717/peerj.12450>.

This package performs fast variable selection in high-dimensional settings while controlling the false discovery rate (FDR) at a user-defined target level. The package is based on the paper Machkour, Muma, and Palomar (2022) <arXiv:2110.06048>.

This package implements marginal structural models combined with a latent class growth analysis framework for assessing the causal effect of treatment trajectories. Based on the approach described in "Marginal Structural Models with Latent Class Growth Analysis of Treatment Trajectories" Diop, A., Sirois, C., Guertin, J.R., Schnitzer, M.E., Candas, B., Cossette, B., Poirier, P., Brophy, J., Mésidor, M., Blais, C. and Hamel, D., (2023) <doi:10.1177/09622802231202384>.

This contains functions that can be used to estimate the time-dependent precision-recall curve (PRC) and the corresponding area under the PRC for right-censored survival data. It also compute time-dependent ROC curve and its corresponding area under the ROC curve (AUC). See Beyene, Chen and Kifle (2024) <doi:10.1002/bimj.202300135>.

Tests one hypothesis with several test statistics, correcting for multiple testing. The central function in the package is testtwice(). In a sensitivity analysis, the method has the largest design sensitivity of its component tests. The package implements the method and examples in Rosenbaum, P. R. (2012) <doi:10.1093/biomet/ass032> Testing one hypothesis twice in observational studies. Biometrika, 99(4), 763-774.

An implementation of the Thornley transport resistance plant growth model. The package can be used to simulate plant growth as forced by climate system variables. The package provides methods for formatting forcing variables, simulating growth dynamics and calibrating model parameters. For more information see Higgins et al. (2025) TTR.PGM: An R package for modelling the distributions and dynamics of plants using the Thornley transport resistance plant growth model. Methods in Ecology and Evolution. in press.

Implement the Tariff algorithm for coding cause-of-death from verbal autopsies. The Tariff method was originally proposed in James et al (2011) <DOI:10.1186/1478-7954-9-31> and later refined as Tariff 2.0 in Serina, et al. (2015) <DOI:10.1186/s12916-015-0527-9>. Note that this package was not developed by authors affiliated with the Institute for Health Metrics and Evaluation and thus unintentional discrepancies may exist between the this implementation and the implementation available from IHME.

For multiple ranked input lists (full or partial) representing the same set of N objects, the package TopKLists <doi:10.1515/sagmb-2014-0093> offers (1) statistical inference on the lengths of informative top-k lists, (2) stochastic aggregation of full or partial lists, and (3) graphical tools for the statistical exploration of input lists, and for the visualization of aggregation results. Note that RGtk2 and gWidgets2RGtk2 have been archived on CRAN. See <https://github.com/pievos101/TopKLists> for installation instructions.

This package provides functions for admin needs of employees of Thomas Jefferson University and Thomas Jefferson University Hospital, Philadelphia, PA.

Tri-hierarchical incomplete block design is defined as an arrangement of v treatments each replicated r times in a three system of blocks if, each block of the first system contains m_1 blocks of second system and each block of the second system contains m_2 blocks of the third system. Ignoring the first and second system of blocks, it leaves an incomplete block design with b_3 blocks of size k_3i units; ignoring first and third system of blocks, it leaves an incomplete block design with b_2 blocks each of size k_2i units and ignoring the second and third system of blocks, it leaves an incomplete block design with b_1 blocks each of size k_1 units. For dealing with experimental circumstances where there are three nested sources of variation, a tri-hierarchical incomplete block design can be adopted. Tri - hierarchical incomplete block designs can find application potential in obtaining mating-environmental designs for breeding trials. To know more about nested block designs one can refer Preece (1967) <doi:10.1093/biomet/54.3-4.479>. This package includes series1(), series2(), series3() and series4() functions. This package generates tri-hierarchical designs with six component designs under certain parameter restrictions.

This package implements the truncated harmonic mean estimator (THAMES) of the reciprocal marginal likelihood using posterior samples and unnormalized log posterior values via reciprocal importance sampling. Metodiev, Perrot-Dockès, Ouadah, Irons, Latouche, & Raftery (2024). Bayesian Analysis. <doi:10.1214/24-BA1422>.

Implementation of a Bayesian two-way latent structure model for integrative genomic clustering. The model clusters samples in relation to distinct data sources, with each subject-dataset receiving a latent cluster label, though cluster labels have across-dataset meaning because of the model formulation. A common scaling across data sources is unneeded, and inference is obtained by a Gibbs Sampler. The model can fit multivariate Gaussian distributed clusters or a heavier-tailed modification of a Gaussian density. Uniquely among integrative clustering models, the formulation makes no nestedness assumptions of samples across data sources -- the user can still fit the model if a study subject only has information from one data source. The package provides a variety of post-processing functions for model examination including ones for quantifying observed alignment of clusterings across genomic data sources. Run time is optimized so that analyses of datasets on the order of thousands of features on fewer than 5 datasets and hundreds of subjects can converge in 1 or 2 days on a single CPU. See "Swanson DM, Lien T, Bergholtz H, Sorlie T, Frigessi A, Investigating Coordinated Architectures Across Clusters in Integrative Studies: a Bayesian Two-Way Latent Structure Model, 2018, <doi:10.1101/387076>, Cold Spring Harbor Laboratory" at <https://www.biorxiv.org/content/early/2018/08/07/387076.full.pdf> for model details.