Allows search and visualisation of a collection of uniformly processed skeletal transcriptomic datasets. Includes methods to identify datasets where genes of interest are differentially expressed and find datasets with a similar gene expression pattern to a query dataset Soul J, Hardingham TE, Boot-Handford RP, Schwartz JM (2019) <doi:10.1093/bioinformatics/bty947>.

Send email using Sendgrid <https://sendgrid.com/> mail API(v3) <https://docs.sendgrid.com/api-reference/how-to-use-the-sendgrid-v3-api/authentication>.

This package provides a template dashboard system with AI agent integrated. Comes with default themes that can be customized. Developers can upload modified templates on Github', and users can easily download templates with RStudio project wizard. The key features of the default template include light and dark theme switcher, resizing graphs, synchronizing inputs across sessions, new notification system, fancy progress bars, and card-like flip panels with back sides, as well as various of HTML tool widgets.

Spike and slab for prediction and variable selection in linear regression models. Uses a generalized elastic net for variable selection.

Enables the complete removal of various Shiny components, such as inputs, outputs and modules. It also aids in the removal of observers that have been created in dynamically created modules.

Settings and functions to extend the knitr SAS engine.

Genomic and multi-environmental soybean data. Soybean Nested Association Mapping (SoyNAM) project dataset funded by the United Soybean Board (USB). BLUP function formats data for genome-wide prediction and association analysis.

This package provides a collection of functions to deal with spatial and spatiotemporal autoregressive conditional heteroscedasticity (spatial ARCH and GARCH models) by Otto, Schmid, Garthoff (2018, Spatial Statistics) <doi:10.1016/j.spasta.2018.07.005>: simulation of spatial ARCH-type processes (spARCH, log/exponential-spARCH, complex-spARCH); quasi-maximum-likelihood estimation of the parameters of spARCH models and spatial autoregressive models with spARCH disturbances, diagnostic checks, visualizations.

This package provides a novel semi-supervised machine learning algorithm to predict phenotype event times using Electronic Health Record (EHR) data.

Implementation for sparse logistic functional principal component analysis (SLFPCA). SLFPCA is specifically developed for functional binary data, and the estimated eigenfunction can be strictly zero on some sub-intervals, which is helpful for interpretation. The crucial function of this package is SLFPCA().

Ordinary and modified statistics for symmetrical linear regression models with small samples. The supported ordinary statistics include Wald, score, likelihood ratio and gradient. The modified statistics include score, likelihood ratio and gradient. Diagnostic tools associated with the fitted model are implemented. For more details see Medeiros and Ferrari (2017) <DOI:10.1111/stan.12107>.

This package provides tools for splitting large Excel worksheets into multiple smaller sheets based on a specified number of rows per chunk. The package reads Excel files, partitions the data efficiently using the data.table package, and writes the resulting subsets into a single workbook with multiple sheets using the openxlsx package. This is useful for handling large datasets, preparing data for reporting, and exporting manageable Excel files for downstream analysis.

The sinaplot is a data visualization chart suitable for plotting any single variable in a multiclass data set. It is an enhanced jitter strip chart, where the width of the jitter is controlled by the density distribution of the data within each class.

This package provides a collection of functions to read, write and manipulate video subtitles. Supported formats include srt', subrip', sub', subviewer', microdvd', ssa', ass', substation', vtt', and webvtt'.

This package provides tools for analyzing spatial cell-cell interactions based on ligand-receptor pairs, including functions for local, regional, and global analysis using spatial transcriptomics data. Integrates with databases like CellChat <https://github.com/jinworks/CellChat>, CellPhoneDB <https://www.cellphonedb.org/>, Cellinker <https://www.rna-society.org/cellinker/>, ICELLNET <https://github.com/soumelis-lab/ICELLNET>, and ConnectomeDB <https://humanconnectome.org/software/connectomedb/> to identify ligand-receptor pairs, visualize interactions through heatmaps, chord diagrams, and infer interactions on different spatial scales.

This package provides flexible and efficient tools for integrating external risk scores into Cox proportional hazards models while accounting for population heterogeneity. Enables robust estimation, improved predictive accuracy, and user-friendly workflows for modern survival analysis. For more information, see Wang et al. (2023) <doi:10.48550/arXiv.2302.11123>.

An algorithm to cluster satellite hot spot data spatially and temporally.

This package performs simulation and inference of diffusion processes on circle. Stochastic correlation models based on circular diffusion models are provided. For details see Majumdar, S. and Laha, A.K. (2024) "Diffusion on the circle and a stochastic correlation model" <doi:10.48550/arXiv.2412.06343>.

This package implements a method for fitting a bounded probability distribution to quantiles (for example stated by an expert), see Bornkamp and Ickstadt (2009) for details. For this purpose B-splines are used, and the density is obtained by penalized least squares based on a Brier entropy penalty. The package provides methods for fitting the distribution as well as methods for evaluating the underlying density and cdf. In addition methods for plotting the distribution, drawing random numbers and calculating quantiles of the obtained distribution are provided.

Statistical methods for estimating and inferring the mean of functional data. The methods include simultaneous confidence bands, local polynomial fitting, bandwidth selection by plug-in and cross-validation, goodness-of-fit tests for parametric models, equality tests for two-sample problems, and plotting functions.

Set of tools aimed at wrapping some of the functionalities of the packages tools, utils and codetools into a nicer format so that an IDE can use them.

This package provides tools to simulate and analyse datasets of social interactions between individuals using hierarchical Bayesian models implemented in Stan. Model fitting is performed via the rstan package. Users can generate realistic interaction data where individual phenotypes influence and respond to those of their partners, with control over sampling design parameters such as the number of individuals, partners, and repeated dyads. The simulation framework allows flexible control over variation and correlation in mean trait values, social responsiveness, and social impact, making it suitable for research on interacting phenotypes and on direct and indirect genetic effects ('DGEs and IGEs'). The package also includes functions to fit and compare alternative models of social effects, including impactâ responsiveness, varianceâ partitioning, and trait-based models, and to summarise model performance in terms of bias and dispersion. For a more detailed description of the available models and impactâ responsiveness, see the accompanying article Wijnhorst et al. (2026) <doi:10.1093/jeb/voag013>.

Estimate Bayesian nested mixture models via Markov Chain Monte Carlo methods. Specifically, the package implements the common atoms model (Denti et al., 2023), and hybrid finite-infinite models. All models use Gaussian mixtures with a normal-inverse-gamma prior distribution on the parameters. Additional functions are provided to help analyzing the results of the fitting procedure. References: Denti, Camerlenghi, Guindani, Mira (2023) <doi:10.1080/01621459.2021.1933499>, Dâ Angelo, Denti (2024) <doi:10.1214/24-BA1458>.

Simultaneous tests and confidence intervals are provided for one-way experimental designs with one or many normally distributed, primary response variables (endpoints). Differences (Hasler and Hothorn, 2011 <doi:10.2202/1557-4679.1258>) or ratios (Hasler and Hothorn, 2012 <doi:10.1080/19466315.2011.633868>) of means can be considered. Various contrasts can be chosen, unbalanced sample sizes are allowed as well as heterogeneous variances (Hasler and Hothorn, 2008 <doi:10.1002/bimj.200710466>) or covariance matrices (Hasler, 2014 <doi:10.1515/ijb-2012-0015>).