This package provides tools to analyze sex differences in omics data for complex diseases. It includes functions for differential expression analysis using the limma method <doi:10.1093/nar/gkv007>, interaction testing between sex and disease, pathway enrichment with clusterProfiler <doi:10.1089/omi.2011.0118>, and gene regulatory network (GRN) construction and analysis using igraph'. The package enables a reproducible workflow from raw data processing to biological interpretation.

An extension for the xml2 package to transform XML documents by applying an xslt style-sheet.

The xtdml package implements partially linear panel regression (PLPR) models with high-dimensional confounding variables and an exogenous treatment variable within the double machine learning framework. The package is used to estimate the structural parameter (treatment effect) in static panel data models with fixed effects using the approaches established in Clarke and Polselli (2025) <doi:10.1093/ectj/utaf011>. xtdml follows the object-oriented architecture of DoubleML (Bach et al., 2024) <doi:10.18637/jss.v108.i03> and uses the mlr3 ecosystem.

The X13-ARIMA-SEATS <https://www.census.gov/data/software/x13as.html> methodology and software is a widely used software and developed by the US Census Bureau. It can be accessed from R with this package and X13-ARIMA-SEATS binaries are provided by the R package x13binary'.

Edit XMP metadata <https://en.wikipedia.org/wiki/Extensible_Metadata_Platform> in a variety of media file formats as well as edit bookmarks (aka outline aka table of contents) and documentation info entries in pdf files. Can detect and use a variety of command-line tools to perform these operations such as exiftool <https://exiftool.sourceforge.net/>, ghostscript <https://www.ghostscript.com/>, and/or pdftk <https://gitlab.com/pdftk-java/pdftk>.

This package implements the Durbin-Hausman panel cointegration tests of Westerlund (2008) <doi:10.1002/jae.967>. The tests are robust to cross-sectional dependence through common factor extraction using principal components. Provides both group-mean (DHg) and panel (DHp) test statistics with automatic factor number selection via information criteria.

This package provides a high-level interface for creating and exporting summary tables to Excel'. Built on dplyr and openxlsx', it provides tools for generating one-way to n-way tables, and summarizing multiple response questions and question blocks. Tables are exported with native Excel formatting, including titles, footnotes, and basic styling options.

Implementation of a scalable, highly configurable, and e(x)tended architecture for (e)volutionary and (g)enetic (a)lgorithms. Multiple representations (binary, real-coded, permutation, and derivation-tree), a rich collection of genetic operators, as well as an extended processing pipeline are provided for genetic algorithms (Goldberg, D. E. (1989, ISBN:0-201-15767-5)), differential evolution (Price, Kenneth V., Storn, Rainer M. and Lampinen, Jouni A. (2005) <doi:10.1007/3-540-31306-0>), simulated annealing (Aarts, E., and Korst, J. (1989, ISBN:0-471-92146-7)), grammar-based genetic programming (Geyer-Schulz (1997, ISBN:978-3-7908-0830-X)), grammatical evolution (Ryan, C., O'Neill, M., and Collins, J. J. (2018) <doi:10.1007/978-3-319-78717-6>), and grammatical differential evolution (O'Neill, M. and Brabazon, A. (2006) in Arabinia, H. (2006, ISBN:978-193-241596-3). All algorithms reuse basic adaptive mechanisms for performance optimization. For the architecture, see Geyer-Schulz, A. (2025) <doi:10.5445/IR/1000187255>. Sequential or parallel execution with master-slave pattern (on multi-core machines, local clusters, and high-performance computing environments) is available for all algorithms. See <https://github.com/ageyerschulz/xega/tree/main/examples/executionModel>. Homogeneous and heterogeneous island models with asynchronous and synchronous communication and configurable communication topology as well as migration strategy are supported. See <https://github.com/ageyerschulz/xega/tree/main/examples/IslandModels>.

This package provides a fast and elegant interface for generating XML fragments and documents. It can be used in companion with R packages XML or xml2 to generate XML documents. The fast XML generation is implemented using the Rcpp package.

This package implements the interactive fixed effects ('IFE') panel estimator of Bai (2009) <doi:10.3982/ECTA6135> for balanced and unbalanced panels, with optional additive unit and/or time fixed effects. Provides analytical standard errors ('homoskedastic', HC1 heteroskedasticity-robust, cluster-robust by unit, and heteroskedasticity- and autocorrelation- consistent), together with asymptotic incidental-parameter bias correction for large panels, including a dynamic extension for predetermined (lagged-dependent) regressors following Moon and Weidner (2017) <doi:10.1017/S0266466615000328>. The number of factors is chosen by information criteria (Bai and Ng 2002 <doi:10.1111/1468-0262.00273>) or by singular value thresholding. Unbalanced panels are handled by an expectation-maximisation algorithm with nuclear-norm-regularised initialisation, with estimation, analytical inference, and bias correction following Su, Wang and Wang (2025) <doi:10.2139/ssrn.5177283> and building on the matrix-completion and missing-data factor analysis of Bai and Ng (2021) <doi:10.1080/01621459.2021.1967163>. All computations use base R only, with no external dependencies.

Computes robust association measures that do not presuppose linearity. The xi correlation (xicor) is based on cross correlation between ranked increments. The reference for the methods implemented here is Chatterjee, Sourav (2020) <arXiv:1909.10140> This package includes the Galton peas example.

This package provides functions for Estimating a (c)DCC-GARCH Model in large dimensions based on a publication by Engle et,al (2017) <doi:10.1080/07350015.2017.1345683> and Nakagawa et,al (2018) <doi:10.3390/ijfs6020052>. This estimation method is consist of composite likelihood method by Pakel et al. (2014) <http://paneldataconference2015.ceu.hu/Program/Cavit-Pakel.pdf> and (Non-)linear shrinkage estimation of covariance matrices by Ledoit and Wolf (2004,2015,2016). (<doi:10.1016/S0047-259X(03)00096-4>, <doi:10.1214/12-AOS989>, <doi:10.1016/j.jmva.2015.04.006>).

Derivation tree operations are needed for implementing grammar-based genetic programming and grammatical evolution: Generating a random derivation trees of a context-free grammar of bounded depth, decoding a derivation tree, choosing a random node in a derivation tree, extracting a tree whose root is a specified node, and inserting a subtree into a derivation tree at a specified node. These operations are necessary for the initialization and for decoders of a random population of programs, as well as for implementing crossover and mutation operators. Depth-bounds are guaranteed by switching to a grammar without recursive production rules. For executing the examples, the package BNF is needed. The basic tree operations for generating, extracting, and inserting derivation trees as well as the conditions for guaranteeing complete derivation trees have been presented in Geyer-Schulz (1997, ISBN:978-3-7908-0830-X). The use of random integer vectors for the generation of derivation trees has been introduced in Ryan, C., Collins, J. J., and O'Neill, M. (1998) <doi:10.1007/BFb0055930> for grammatical evolution.

Reading and writing sheets of a single Excel file into and from a list of data frames. Eases I/O of tabular data in bioinformatics while keeping them in a human readable format.

High-level functions to render LaTeX fragments in plots, including as labels and data symbols in ggplot2 plots, plus low-level functions to author LaTeX fragments (to produce LaTeX documents), typeset LaTeX documents (to produce DVI files), read DVI files (to produce "DVI" objects), and render "DVI" objects.

Hamiltonian Monte Carlo for both continuous and discontinuous posterior distributions with a customizable trajectory length termination criterion. See Nishimura et al. (2020) <doi:10.1093/biomet/asz083> for the original Discontinuous Hamiltonian Monte Carlo; Hoffman et al. (2014) <doi:10.48550/arXiv.1111.4246> and Betancourt (2016) <doi:10.48550/arXiv.1601.00225> for the definition of possible Hamiltonian Monte Carlo termination criteria.

Adding some at-present missing functionality, or functions unlikely to be added to the base xpose package. This includes some diagnostic plots that have been missing in translation from xpose4', but also some useful features that truly extend the capabilities of what can be done with xpose'. These extensions include the concept of a set of xpose objects, and diagnostics for likelihood-based models.

Supports a structured approach for exploring PKPD data <https://opensource.nibr.com/xgx/>. It also contains helper functions for enabling the modeler to follow best R practices (by appending the program name, figure name location, and draft status to each plot). In addition, it enables the modeler to follow best graphical practices (by providing a theme that reduces chart ink, and by providing time-scale, log-scale, and reverse-log-transform-scale functions for more readable axes). Finally, it provides some data checking and summarizing functions for rapidly exploring pharmacokinetics and pharmacodynamics (PKPD) datasets.

The xlsxjars package collects all the external jars required for the xlxs package. This release corresponds to POI 3.13.

This package provides a set of functions devoted to multivariate exploratory statistics on textual data. Classical methods such as correspondence analysis and agglomerative hierarchical clustering are available. Chronologically constrained agglomerative hierarchical clustering enriched with labelled-by-words trees is offered. Given a division of the corpus into parts, their characteristic words and documents are identified. Further, accessing to FactoMineR functions is very easy. Two of them are relevant in textual domain. MFA() addresses multiple lexical table allowing applications such as dealing with multilingual corpora as well as simultaneously analyzing both open-ended and closed questions in surveys. See <http://xplortext.unileon.es> for examples.

This is a collection of some useful functions when dealing with text data. Currently it only contains a very efficient function of decoding HTML entities in character vectors by Rcpp routine.

Representation-dependent gene-level operations for genetic and evolutionary algorithms with real-coded genes used in the R-package xega <https://CRAN.R-project.org/package=xega> are collected in this package. The common feature of the gene operations is that all of them are useful for derivation-free optimization algorithms. At the moment the package implements initialization, mutation, crossover, and replication operations for differential evolution as described in Price, Kenneth V., Storn, Rainer M. and Lampinen, Jouni A. (2005) <doi:10.1007/3-540-31306-0>. In addition, several (more recent) methods for determining the scale factor are provided. For xega''s architecture, see Geyer-Schulz, A. (2025) <doi:10.5445/IR/1000187255>.

Integrates concepts of stochastic demography into species distribution modelling. The main approach maximizes a likelihood function based on environmental information and presence/absence records. This is used to reconstruct species fundamental ecological niches and to project their potential geographic range. Data requirements include species presence/absence records and a timeseries of environmental data.

Create beautifully color-coordinated and customized themes for your xaringan slides, without writing any CSS. Complete your slide theme with ggplot2 themes that match the font and colors used in your slides. Customized styles can be created directly in your slides R Markdown source file or in a separate external script.