An implementation of double generalized linear model (DGLM) building with variable selection procedures and handling of interaction terms and other complex situations. We also provide a method of handling convergence issues within the dglm() function. The package offers a simulation function for generating simulated data for testing purposes and utilizes the forward stepwise variable selection procedure in model-building. It also provides a new custom bootstrap function for mean and standard deviation estimation and functions for building crossplots and squareplots from a data set.

Provee un acceso conveniente a mas de 17 millones de registros de la base de datos del Censo 2017. Los datos fueron importados desde el DVD oficial del INE usando el Convertidor REDATAM creado por Pablo De Grande. Esta paquete esta documentado intencionalmente en castellano asciificado para que funcione sin problema en diferentes plataformas. (Provides convenient access to more than 17 million records from the Chilean Census 2017 database. The datasets were imported from the official DVD provided by the Chilean National Bureau of Statistics by using the REDATAM converter created by Pablo De Grande and in addition it includes the maps accompanying these datasets.).

Calculates correlation of variables and displays the results graphically. Included panel functions can display points, shading, ellipses, and correlation values with confidence intervals. See Friendly (2002) <doi:10.1198/000313002533>.

This package provides efficient implementation of the Cross-Covariance Isolate Detect (CCID) methodology for the estimation of the number and location of multiple change-points in the second-order (cross-covariance or network) structure of multivariate, possibly high-dimensional time series. The method is motivated by the detection of change points in functional connectivity networks for functional magnetic resonance imaging (fMRI), electroencephalography (EEG), magentoencephalography (MEG) and electrocorticography (ECoG) data. The main routines in the package have been extensively tested on fMRI data. For details on the CCID methodology, please see Anastasiou et al (2022), Cross-covariance isolate detect: A new change-point method for estimating dynamic functional connectivity. Medical Image Analysis, Volume 75.

Utility functions for the statistical analysis of corpus frequency data. This package is a companion to the open-source course "Statistical Inference: A Gentle Introduction for Computational Linguists and Similar Creatures" ('SIGIL').

Estimates the causal decompositions of group disparities developed by Yu and Elwert (2025) <doi:10.1214/24-AOAS1990>. For the nuisance functions of the estimators, we provide both parametric and nonparametric options, as well as manual options in case the default models are not satisfying.

Recalibrate risk scores (predicting binary outcomes) to improve clinical utility of risk score using weighted logistic or constrained logistic recalibration methods. Additionally, produces plots to assess the potential for recalibration to improve the clinical utility of a risk model. Methods are described in detail in Mishra, A. (2019) "Methods for Risk Markers that Incorporate Clinical Utility" <http://hdl.handle.net/1773/44068>.

Calculates equitable overload compensation for college instructors based on institutional policies, enrollment thresholds, and regular teaching load limits. Compensation is awarded only for credit hours that exceed the regular load and meet minimum enrollment criteria. When enrollment is below a specified threshold, pay is prorated accordingly. The package prioritizes compensation from high-enrollment courses, or optionally from low-enrollment courses for fairness, depending on user-defined strategy. Includes tools for flexible policy settings, instructor filtering, and produces clean, audit-ready summary tables suitable for payroll and administrative reporting.

Variance estimation on indicators of income concentration and poverty using complex sample survey designs. Wrapper around the survey package.

This package provides functions for microbiome data analysis that take into account its compositional nature. Performs variable selection through penalized regression for both, cross-sectional and longitudinal studies, and for binary and continuous outcomes.

Perform sparse estimation of a Gaussian graphical model (GGM) with node aggregation through variable clustering. Currently, the package implements the clusterpath estimator of the Gaussian graphical model (CGGM) (Touw, Alfons, Groenen & Wilms, 2025; <doi:10.48550/arXiv.2407.00644>).

This package provides a suite of functions for rapid and flexible analysis of codon usage bias. It provides in-depth analysis at the codon level, including relative synonymous codon usage (RSCU), tRNA weight calculations, machine learning predictions for optimal or preferred codons, and visualization of codon-anticodon pairing. Additionally, it can calculate various gene- specific codon indices such as codon adaptation index (CAI), effective number of codons (ENC), fraction of optimal codons (Fop), tRNA adaptation index (tAI), mean codon stabilization coefficients (CSCg), and GC contents (GC/GC3s/GC4d). It also supports both standard and non-standard genetic code tables found in NCBI, as well as custom genetic code tables.

Implementation of Librino, Levorato, and Zorzi (2014) <doi:10.1002/wcm.2305> algorithm for computation of the intersection areas of an arbitrary number of circles.

It fits finite mixture models for censored or/and missing data using several multivariate distributions. Point estimation and asymptotic inference (via empirical information matrix) are offered as well as censored data generation. Pairwise scatter and contour plots can be generated. Possible multivariate distributions are the well-known normal, Student-t and skew-normal distributions. This package is an complement of Lachos, V. H., Moreno, E. J. L., Chen, K. & Cabral, C. R. B. (2017) <doi:10.1016/j.jmva.2017.05.005> for the multivariate skew-normal case.

This package provides functions calculating Conley (1999) <doi:10.1016/S0304-4076(98)00084-0> standard errors. The package started by merging and extending multiple packages and other published scripts on this econometric technique. It strongly emphasizes computational optimization. Details are available in the function documentation and in the vignette.

Software which provides numerous functionalities for detecting and removing group-level effects from high-dimensional scientific data which, when combined with additional assumptions, allow for causal conclusions, as-described in our manuscripts Bridgeford et al. (2024) <doi:10.1101/2021.09.03.458920> and Bridgeford et al. (2023) <doi:10.48550/arXiv.2307.13868>. Also provides a number of useful utilities for generating simulations and balancing covariates across multiple groups/batches of data via matching and propensity trimming for more than two groups.

This package contains 3 maps. 1) US States 2) US Counties 3) Countries of the world.

Computes 138 standard climate indices at monthly, seasonal and annual resolution. These indices were selected, based on their direct and significant impacts on target sectors, after a thorough review of the literature in the field of extreme weather events and natural hazards. Overall, the selected indices characterize different aspects of the frequency, intensity and duration of extreme events, and are derived from a broad set of climatic variables, including surface air temperature, precipitation, relative humidity, wind speed, cloudiness, solar radiation, and snow cover. The 138 indices have been classified as follow: Temperature based indices (42), Precipitation based indices (22), Bioclimatic indices (21), Wind-based indices (5), Aridity/ continentality indices (10), Snow-based indices (13), Cloud/radiation based indices (6), Drought indices (8), Fire indices (5), Tourism indices (5).

This package provides functions designed to simulate data that conform to basic unidimensional IRT models (for now 3-parameter binary response models and graded response models) along with Post-Hoc CAT simulations of those models given various item selection methods, ability estimation methods, and termination criteria. See Wainer (2000) <doi:10.4324/9781410605931>, van der Linden & Pashley (2010) <doi:10.1007/978-0-387-85461-8_1>, and Eggen (1999) <doi:10.1177/01466219922031365> for more details.

Enhancing T cell receptor (TCR) sequence analysis, ClusTCR2', based on ClusTCR python program, leverages Hamming distance to compare the complement-determining region three (CDR3) sequences for sequence similarity, variable gene (V gene) and length. The second step employs the Markov Cluster Algorithm to identify clusters within an undirected graph, providing a summary of amino acid motifs and matrix for generating network plots. Tailored for single-cell RNA-seq data with integrated TCR-seq information, ClusTCR2 is integrated into the Single Cell TCR and Expression Grouped Ontologies (STEGO) R application or STEGO.R'. See the two publications for more details. Sebastiaan Valkiers, Max Van Houcke, Kris Laukens, Pieter Meysman (2021) <doi:10.1093/bioinformatics/btab446>, Kerry A. Mullan, My Ha, Sebastiaan Valkiers, Nicky de Vrij, Benson Ogunjimi, Kris Laukens, Pieter Meysman (2023) <doi:10.1101/2023.09.27.559702>.

An integrated set of tools for thermodynamic calculations in aqueous geochemistry and geobiochemistry. Functions are provided for writing balanced reactions to form species from user-selected basis species and for calculating the standard molal properties of species and reactions, including the standard Gibbs energy and equilibrium constant. Calculations of the non-equilibrium chemical affinity and equilibrium chemical activity of species can be portrayed on diagrams as a function of temperature, pressure, or activity of basis species; in two dimensions, this gives a maximum affinity or predominance diagram. The diagrams have formatted chemical formulas and axis labels, and water stability limits can be added to Eh-pH, oxygen fugacity- temperature, and other diagrams with a redox variable. The package has been developed to handle common calculations in aqueous geochemistry, such as solubility due to complexation of metal ions, mineral buffers of redox or pH, and changing the basis species across a diagram ("mosaic diagrams"). CHNOSZ also implements a group additivity algorithm for the standard thermodynamic properties of proteins.

This package provides a daily summary of the Coronavirus (COVID-19) cases by state/province. Data source: Johns Hopkins University Center for Systems Science and Engineering (JHU CCSE) Coronavirus <https://systems.jhu.edu/research/public-health/ncov/>.

The reliability of clusters is estimated using random projections. A set of stability measures is provided to assess the reliability of the clusters discovered by a generic clustering algorithm. The stability measures are taylored to high dimensional data (e.g. DNA microarray data) (Valentini, G (2005), <doi:10.1093/bioinformatics/bti817>.

Deal with packages check outputs and reduce the risk of rejection by CRAN by following policies.