Compare dissolution profiles with confidence interval of similarity factor f2 using bootstrap methodology as described in the literature, such as Efron and Tibshirani (1993, ISBN:9780412042317), Davison and Hinkley (1997, ISBN:9780521573917), and Shah et al. (1998) <doi:10.1023/A:1011976615750>. The package can also be used to simulate dissolution profiles based on mathematical modelling and multivariate normal distribution.

These are miscellaneous functions for working with panel data, quantiles, and printing results. For panel data, the package includes functions for making a panel data balanced (that is, dropping missing individuals that have missing observations in any time period), converting id numbers to row numbers, and to treat repeated cross sections as panel data under the assumption of rank invariance. For quantiles, there are functions to make distribution functions from a set of data points (this is particularly useful when a distribution function is created in several steps), to combine distribution functions based on some external weights, and to invert distribution functions. Finally, there are several other miscellaneous functions for obtaining weighted means, weighted distribution functions, and weighted quantiles; to generate summary statistics and their differences for two groups; and to add or drop covariates from formulas.

This data package contains a subset of the Bodenmiller et al, Nat Biotech 2012 dataset for testing single cell, high dimensional analysis and visualization methods.

Unified and user-friendly framework for using new distributional representations of biosensors data in different statistical modeling tasks: regression models, hypothesis testing, cluster analysis, visualization, and descriptive analysis. Distributional representations are a functional extension of compositional time-range metrics and we have used them successfully so far in modeling glucose profiles and accelerometer data. However, these functional representations can be used to represent any biosensor data such as ECG or medical imaging such as fMRI. Matabuena M, Petersen A, Vidal JC, Gude F. "Glucodensities: A new representation of glucose profiles using distributional data analysis" (2021) <doi:10.1177/0962280221998064>.

Plotting package based on the grid system, combining elements of a bubble plot and heatmap to conveniently display two numerical variables, (represented by color and size) grouped by categorical variables on the x and y axes. This is a useful alternative to a forest plot when the data can be grouped in two dimensions, such as predictors x outcomes. It has particular advantages for visualising the metabolic measures produced by the Nightingale Health metabolomics platform, and templates are included for automatically generating figures from these datasets.

Estimates the density of a variable in a measurement error setup, potentially with an excess of zero values. For more details see Sarkar (2022) <doi:10.1080/01621459.2020.1782220>.

Assess the agreement in method comparison studies by tolerance intervals and errors-in-variables (EIV) regressions. The Ordinary Least Square regressions (OLSv and OLSh), the Deming Regression (DR), and the (Correlated)-Bivariate Least Square regressions (BLS and CBLS) can be used with unreplicated or replicated data. The BLS() and CBLS() are the two main functions to estimate a regression line, while XY.plot() and MD.plot() are the two main graphical functions to display, respectively an (X,Y) plot or (M,D) plot with the BLS or CBLS results. Four hyperbolic statistical intervals are provided: the Confidence Interval (CI), the Confidence Bands (CB), the Prediction Interval and the Generalized prediction Interval. Assuming no proportional bias, the (M,D) plot (Band-Altman plot) may be simplified by calculating univariate tolerance intervals (beta-expectation (type I) or beta-gamma content (type II)). Major updates from last version 1.0.0 are: title shortened, include the new functions BLS.fit() and CBLS.fit() as shortcut of the, respectively, functions BLS() and CBLS(). References: B.G. Francq, B. Govaerts (2016) <doi:10.1002/sim.6872>, B.G. Francq, B. Govaerts (2014) <doi:10.1016/j.chemolab.2014.03.006>, B.G. Francq, B. Govaerts (2014) <http://publications-sfds.fr/index.php/J-SFdS/article/view/262>, B.G. Francq (2013), PhD Thesis, UCLouvain, Errors-in-variables regressions to assess equivalence in method comparison studies, <https://dial.uclouvain.be/pr/boreal/object/boreal%3A135862/datastream/PDF_01/view>.

BabyTime is an application for tracking infant and toddler care activities like sleeping, eating, etc. This package will take the outputted .zip files and parse it into a usable list object with cleaned data. It handles malformed and incomplete data gracefully and is designed to parse one directory at a time.

This package provides the bayesGARCH() function which performs the Bayesian estimation of the GARCH(1,1) model with Student's t innovations as described in Ardia (2008) <doi:10.1007/978-3-540-78657-3>.

Implementation of the bunching estimator for kinks and notches. Allows for flexible estimation of counterfactual (e.g. controlling for round number bunching, accounting for other bunching masses within bunching window, fixing bunching point to be minimum, maximum or median value in its bin, etc.). It produces publication-ready plots in the style followed since Chetty et al. (2011) <doi:10.1093/qje/qjr013>, with lots of functionality to set plot options.

Fits finite mixture models of univariate Gaussian distributions using JAGS within a Bayesian framework.

This package provides an interface to data provided by the Bank for International Settlements <https://www.bis.org>, allowing for programmatic retrieval of a large quantity of (central) banking data.

This package creates plots showing scored HR experiments and plots of distribution of means of ranks of HR score from bootstrapping. Authors (2019) <doi:10.5281/zenodo.3374507>.

Generate the James Blinding Index, as described in James et al (1996) <https://pubmed.ncbi.nlm.nih.gov/8841652/> and the Bang Blinding Index, as described in Bang et al (2004) <https://pubmed.ncbi.nlm.nih.gov/15020033/>. These are measures to assess whether or not satisfactory blinding has been maintained in a randomized, controlled, clinical trial. These can be generated for trial subjects, research coordinators and principal investigators, based upon standardized questionnaires that have been administered, to assess whether or not they can correctly guess to which treatment arm (e.g. placebo or treatment) subjects were assigned at randomization.

Extend the bigmemory package with various analytics. Functions bigkmeans and binit may also be used with native R objects. For tapply'-like functions, the bigtabulate package may also be helpful. For linear algebra support, see bigalgebra'. For mutex (locking) support for advanced shared-memory usage, see synchronicity'.

This package provides a Bayesian, global planktic foraminifera core top calibration to modern sea-surface temperatures. Includes four calibration models, considering species-specific calibration parameters and seasonality.

Fit and simulate bivariate correlated frailty models with proportional hazard structure. Frailty distributions, such as gamma and lognormal models are supported semiparametric procedures. Frailty variances of the two subjects can be varied or equal. Details on the models are available in book of Wienke (2011,ISBN:978-1-4200-7388-1). Bivariate gamma fit is obtained using the approach given in Kifle et al (2023) <DOI: 10.4310/22-SII738> with modifications. Lognormal fit is based on the approach by Ripatti and Palmgren (2000) <doi:10.1111/j.0006-341X.2000.01016.x>. Frailty distributions, such as gamma, inverse gaussian and power variance frailty models are supported for parametric approach.

Set of functions to perform various bootstrap unit root tests for both individual time series (including augmented Dickey-Fuller test and union tests), multiple time series and panel data; see Smeekes and Wilms (2023) <doi:10.18637/jss.v106.i12>, Palm, Smeekes and Urbain (2008) <doi:10.1111/j.1467-9892.2007.00565.x>, Palm, Smeekes and Urbain (2011) <doi:10.1016/j.jeconom.2010.11.010>, Moon and Perron (2012) <doi:10.1016/j.jeconom.2012.01.008>, Smeekes and Taylor (2012) <doi:10.1017/S0266466611000387> and Smeekes (2015) <doi:10.1111/jtsa.12110> for key references.

Currently, the package provides several functions for plotting and analyzing bibliometric data (JIF, Journal Impact Factor, and paper percentile values), beamplots with citations and percentiles, and three plot functions to visualize the result of a reference publication year spectroscopy (RPYS) analysis performed in the free software CRExplorer (see <http://crexplorer.net>). Further extension to more plot variants is planned.

This package provides access to a range of functions for analyzing, applying and visualizing Bayesian response-adaptive trial designs for a binary endpoint. Includes the predictive probability approach and the predictive evidence value designs for binary endpoints.

Cobb's maximum likelihood method for cusp-catastrophe modeling (Grasman, van der Maas, and Wagenmakers (2009) <doi:10.18637/jss.v032.i08>; Cobb (1981), Behavioral Science, 26(1), 75-78). Includes a cusp() function for model fitting, and several utility functions for plotting, and for comparing the model to linear regression and logistic curve models.

This package provides a comprehensive framework for time series omics analysis, integrating changepoint detection, smooth and shape-constrained trends, and uncertainty quantification. It supports gene- and transcript-level inferences, p-value aggregation for improved power, and both case-only and case-control designs. It includes an interactive shiny interface. The methods are described in Yates et al. (2024) <doi:10.1101/2024.12.22.630003>.

Data sets used for copula modeling in addition to those in the R package copula'. These include a random subsample from the US National Education Longitudinal Study (NELS) of 1988 and nursing home data from Wisconsin.

This package provides a self-contained set of methods to aid clinical trial safety investigators, statisticians and researchers, in the early detection of adverse events using groupings by body-system or system organ class. This work was supported by the Engineering and Physical Sciences Research Council (UK) (EPSRC) [award reference 1521741] and Frontier Science (Scotland) Ltd. The package title c212 is in reference to the original Engineering and Physical Sciences Research Council (UK) funded project which was named CASE 2/12.