This package implements a kernel-based association test for copy number variation (CNV) aggregate analysis in a certain genomic region (e.g., gene set, chromosome, or genome) that is robust to the within-locus and across-locus etiological heterogeneity, and bypass the need to define a "locus" unit for CNVs. Brucker, A., et al. (2020) <doi:10.1101/666875>.

This package provides a multi-task learning approach to variable selection regression with highly correlated predictors and sparse effects, based on frequentist statistical inference. It provides statistical evidence to identify which subsets of predictors have non-zero effects on which subsets of response variables, motivated and designed for colocalization analysis across genome-wide association studies (GWAS) and quantitative trait loci (QTL) studies. The ColocBoost model is described in Cao et. al. (2025) <doi:10.1101/2025.04.17.25326042>.

Conditional mixture model fitted via EM (Expectation Maximization) algorithm for model-based clustering, including parsimonious procedure, optimal conditional order exploration, and visualization.

Decorate functions to make them return enhanced output. The enhanced output consists in an object of type chronicle containing the result of the function applied to its arguments, as well as a log detailing when the function was run, what were its inputs, what were the errors (if the function failed to run) and other useful information. Tools to handle decorated functions are included, such as a forward pipe operator that makes chaining decorated functions possible.

Incorporates colour gradients from the cpt-city web archive available at <http://seaviewsensing.com/pub/cpt-city/>.

Estimates the causal decompositions of group disparities developed by Yu and Elwert (2025) <doi:10.1214/24-AOAS1990>. For the nuisance functions of the estimators, we provide both parametric and nonparametric options, as well as manual options in case the default models are not satisfying.

Computes the uniform rate of profit, the vector of price of production and the vector of labor values; and also compute measures of deviation between relative prices of production and relative values. <https://scholarworks.umass.edu/econ_workingpaper/347/>. You provide the input-output data and clptheory does the calculations for you.

Formal psychological models of categorization and learning, independently-replicated data sets against which to test them, and simulation archives.

Routines doing cone projection and quadratic programming, as well as doing estimation and inference for constrained parametric regression and shape-restricted regression problems. See Mary C. Meyer (2013)<doi:10.1080/03610918.2012.659820> for more details.

We design algorithms with linear time complexity with respect to the dimension for three commonly studied correlation structures, including exchangeable, decaying-product and K-dependent correlation structures, and extend the algorithms to generate binary data of general non-negative correlation matrices with quadratic time complexity. Jiang, W., Song, S., Hou, L. and Zhao, H. "A set of efficient methods to generate high-dimensional binary data with specified correlation structures." The American Statistician. See <doi:10.1080/00031305.2020.1816213> for a detailed presentation of the method.

With this package you can run ConMET locally in R. ConMET is an R-shiny application that facilitates performing and evaluating confirmatory factor analyses (CFAs) and is useful for running and reporting typical measurement models in applied psychology and management journals. ConMET automatically creates, compares and summarizes CFA models. Most common fit indices (E.g., CFI and SRMR) are put in an overview table. ConMET also allows to test for common method variance. The application is particularly useful for teaching and instruction of measurement issues in survey research. The application uses the lavaan package (Rosseel, 2012) to run CFAs.

This package provides function declarations and inline function definitions that facilitate communication between R and the Eigen C++ library for linear algebra and scientific computing.

Fits convolution-based nonstationary Gaussian process models to point-referenced spatial data. The nonstationary covariance function allows the user to specify the underlying correlation structure and which spatial dependence parameters should be allowed to vary over space: the anisotropy, nugget variance, and process variance. The parameters are estimated via maximum likelihood, using a local likelihood approach. Also provided are functions to fit stationary spatial models for comparison, calculate the Kriging predictor and standard errors, and create various plots to visualize nonstationarity.

Shiny app for creating interactive consort flow diagrams and other types of flow diagrams, see Moher, Schulz and Altman (2001) <doi:10.1016/S0140-6736(00)04337-3>.

Allows Brownian motion, fractional Brownian motion, and integrated Ornstein-Uhlenbeck process components to be added to linear and non-linear mixed effects models using the structures and methods of the nlme package.

Create rich command line applications, with colors, headings, lists, alerts, progress bars, etc. It uses CSS for custom themes. This package is now superseded by the cli package. Please use cli instead in new projects.

CGAL is a C++ library that aims to provide easy access to efficient and reliable algorithms in computational geometry. Since its version 4, CGAL can be used as standalone header-only library and is available under a double GPL-3|LGPL license. <https://www.cgal.org/>.

This package performs least squares constrained optimization on a linear objective function. It contains a number of algorithms to choose from and offers a formula syntax similar to lm().

This package provides a shiny app to discover cocktails. The app allows one to search for cocktails by ingredient, filter on rating, and number of ingredients. The package also contains data with the ingredients of nearly 26 thousand cocktails scraped from the web.

This package provides a simple way to write ".Rprofile" code in an R Markdown file and have it knit to the correct location for your operating system.

Statistical analysis of axial using distributions Nonnegative Trigonometric Sums (NNTS). The package includes functions for calculation of densities and distributions, for the estimation of parameters, and more. Fernandez-Duran, J.J. and Gregorio-Dominguez, M.M. (2025), Multimodal distributions for circular axial data", <doi:10.48550/arXiv.2504.04681>.

Curates biological sequences massively, quickly, without errors and without internet connection. Biological sequences curing is performed by aligning the forward and / or revers primers or ends of cloning vectors with the sequences to be cleaned. After the alignment, new subsequences are generated without biological fragment not desired by the user. Pozzi et al (2020) <doi:10.1007/s00438-020-01671-z>.

Convert BCD (raw bytes) to decimal numbers and vice versa. BCD format is used to preserve decimals exactly, as opposed to the binary rounding errors inherent in "numeric" or "floating-point" formats.

It fits finite mixture models for censored or/and missing data using several multivariate distributions. Point estimation and asymptotic inference (via empirical information matrix) are offered as well as censored data generation. Pairwise scatter and contour plots can be generated. Possible multivariate distributions are the well-known normal, Student-t and skew-normal distributions. This package is an complement of Lachos, V. H., Moreno, E. J. L., Chen, K. & Cabral, C. R. B. (2017) <doi:10.1016/j.jmva.2017.05.005> for the multivariate skew-normal case.