Create hexagonal heatmaps with ggplot2', using the size aesthetic to variably size each hexagon.

When evaluating the results of a genome-wide association study (GWAS), it is important to perform a quality control to ensure that the results are valid, complete, correctly formatted, and, in case of meta-analysis, consistent with other studies that have applied the same analysis. This package was developed to facilitate and streamline this process and provide the user with a comprehensive report.

Genomic biology is not limited to the confines of the canonical B-forming DNA duplex, but includes over ten different types of other secondary structures that are collectively termed non-B DNA structures. Of these non-B DNA structures, the G-quadruplexes are highly stable four-stranded structures that are recognized by distinct subsets of nuclear factors. This package provide functions for predicting intramolecular G quadruplexes. In addition, functions for predicting other intramolecular nonB DNA structures are included.

An implementation of SPRE (standardised predicted random-effects) statistics in R to explore heterogeneity in genetic association meta- analyses, as described by Magosi et al. (2019) <doi:10.1093/bioinformatics/btz590>. SPRE statistics are precision weighted residuals that indicate the direction and extent with which individual study-effects in a meta-analysis deviate from the average genetic effect. Overly influential positive outliers have the potential to inflate average genetic effects in a meta-analysis whilst negative outliers might lower or change the direction of effect. See the getspres website for documentation and examples <https://magosil86.github.io/getspres/>.

This package provides a statistical hypothesis test for conditional independence. Given residuals from a sufficiently powerful regression, it tests whether the covariance of the residuals is vanishing. It can be applied to both discretely-observed functional data and multivariate data. Details of the method can be found in Anton Rask Lundborg, Rajen D. Shah and Jonas Peters (2022) <doi:10.1111/rssb.12544>.

This package provides a function to retrieve the system timezone on Unix systems which has been found to find an answer when Sys.timezone() has failed. It is based on an answer by Duane McCully posted on StackOverflow', and adapted to be callable from R. The package also builds on Windows, but just returns NULL.

Multi-threaded GIF encoder written in Rust: <https://gif.ski/>. Converts images to GIF animations using pngquant's efficient cross-frame palettes and temporal dithering with thousands of colors per frame.

This package provides methods for recursive partitioning based on the Graded Response Model ('GRM'), extending the MOB algorithm from the partykit package. The package allows for fitting GRM trees that partition the population into homogeneous subgroups based on item response patterns and covariates. Includes specialized plotting functions for visualizing GRM trees with different terminal node displays (threshold regions, parameter profiles, and factor score distributions). For more details on the methods, see Samejima (1969) <doi:10.1002/J.2333-8504.1968.TB00153.X>, Komboz et al. (2018) <doi:10.1177/0013164416664394> and Arimoro et al. (2025) <doi:10.1007/s11136-025-04018-6>.

Download geyser eruption and observation data from the GeyserTimes site (<https://geysertimes.org>) and optionally store it locally. The vignette shows a simple analysis of downloading, accessing, and summarizing the data.

This package provides tools to download comprehensive datasets of local, state, and federal election results in Germany from 1990 to 2025. The package facilitates access to data on turnout, vote shares for major parties, and demographic information across different levels of government (municipal, state, and federal). It offers access to geographically harmonized datasets that account for changes in municipal boundaries over time and incorporate mail-in voting districts. Users can easily retrieve, clean, and standardize German electoral data, making it ready for analysis. Data is sourced from <https://github.com/awiedem/german_election_data>.

Assists in the plotting and functional smoothing of traits measured over time and the extraction of features from these traits, implementing the SET (Smoothing and Extraction of Traits) method described in Brien et al. (2020) Plant Methods, 16. Smoothing of growth trends for individual plants using natural cubic smoothing splines or P-splines is available for removing transient effects and segmented smoothing is available to deal with discontinuities in growth trends. There are graphical tools for assessing the adequacy of trait smoothing, both when using this and other packages, such as those that fit nonlinear growth models. A range of per-unit (plant, pot, plot) growth traits or features can be extracted from the data, including single time points, interval growth rates and other growth statistics, such as maximum growth or days to maximum growth. The package also has tools adapted to inputting data from high-throughput phenotyping facilities, such from a Lemna-Tec Scananalyzer 3D (see <https://www.youtube.com/watch?v=MRAF_mAEa7E/> for more information). The package growthPheno can also be installed from <http://chris.brien.name/rpackages/>.

Approximate frequentist inference for generalized linear mixed model analysis with expectation propagation used to circumvent the need for multivariate integration. In this version, the random effects can be any reasonable dimension. However, only probit mixed models with one level of nesting are supported. The methodology is described in Hall, Johnstone, Ormerod, Wand and Yu (2018) <arXiv:1805.08423v1>.

Estimates within and between time point interactions in experience sampling data, using the Graphical vector autoregression model in combination with regularization. See also Epskamp, Waldorp, Mottus & Borsboom (2018) <doi:10.1080/00273171.2018.1454823>.

Gitea is a community managed, lightweight code hosting solution were projects and their respective git repositories can be managed <https://gitea.io>. This package gives an interface to the Gitea API to access and manage repositories, issues and organizations directly in R.

This package provides a simple API for downloading and reading xml data directly from Lattes <http://lattes.cnpq.br/>.

Fits a generalized linear density ratio model (GLDRM). A GLDRM is a semiparametric generalized linear model. In contrast to a GLM, which assumes a particular exponential family distribution, the GLDRM uses a semiparametric likelihood to estimate the reference distribution. The reference distribution may be any discrete, continuous, or mixed exponential family distribution. The model parameters, which include both the regression coefficients and the cdf of the unspecified reference distribution, are estimated by maximizing a semiparametric likelihood. Regression coefficients are estimated with no loss of efficiency, i.e. the asymptotic variance is the same as if the true exponential family distribution were known. Huang (2014) <doi:10.1080/01621459.2013.824892>. Huang and Rathouz (2012) <doi:10.1093/biomet/asr075>. Rathouz and Gao (2008) <doi:10.1093/biostatistics/kxn030>.

The gRbase package provides graphical modelling features used by e.g. the packages gRain', gRim and gRc'. gRbase implements graph algorithms including (i) maximum cardinality search (for marked and unmarked graphs). (ii) moralization, (iii) triangulation, (iv) creation of junction tree. gRbase facilitates array operations, gRbase implements functions for testing for conditional independence. gRbase illustrates how hierarchical log-linear models may be implemented and describes concept of graphical meta data. The facilities of the package are documented in the book by Højsgaard, Edwards and Lauritzen (2012, <doi:10.1007/978-1-4614-2299-0>) and in the paper by Dethlefsen and Højsgaard, (2005, <doi:10.18637/jss.v014.i17>). Please see citation("gRbase") for citation details.

Statistical functions to fit, validate and describe a Generalized Waring Regression Model (GWRM).

The philosophy in the package is described in Stasny (1988) <doi:10.2307/1391558> and Gutierrez, A., Trujillo, L. & Silva, N. (2014), <ISSN:1492-0921> to estimate the gross flows under complex surveys using a Markov chain approach with non response.

Group method of data handling (GMDH) - type neural network algorithm is the heuristic self-organization method for modelling the complex systems. In this package, GMDH-type neural network algorithms are applied to make short term forecasting for a univariate time series.

This package provides methods for dividing data into groups. Create balanced partitions and cross-validation folds. Perform time series windowing and general grouping and splitting of data. Balance existing groups with up- and downsampling or collapse them to fewer groups.

Generalized Mann-Whitney type tests based on probabilistic indices and new diagnostic plots, for the underlying manuscript see Fischer, Oja (2015) <doi:10.18637/jss.v065.i09>.

Individual-based simulations forward in time, simulating how patterns in ancestry along the genome change after admixture. Full description can be found in Janzen (2021) <doi:10.1111/2041-210X.13612>.

This package provides a network-based gene weighting algorithm for pathway enrichment analysis, using either RNA-seq or microarray data. Zhaoyuan Fang, Weidong Tian and Hongbin Ji (2012) <doi:10.1038/cr.2011.149>.