Causal Inference Assistance (CIA) for performing causal inference within the structural causal modelling framework. Structure learning is performed using partition Markov chain Monte Carlo (Kuipers & Moffa, 2017) and several additional functions have been added to help with causal inference. Kuipers and Moffa (2017) <doi:10.1080/01621459.2015.1133426>.

CLUster Evaluation (CLUE) is a computational method for identifying optimal number of clusters in a given time-course dataset clustered by cmeans or kmeans algorithms and subsequently identify key kinases or pathways from each cluster. Its implementation in R is called ClueR. See README on <https://github.com/PYangLab/ClueR> for more details. P Yang et al. (2015) <doi:10.1371/journal.pcbi.1004403>.

This package provides correlation-based penalty estimators for both linear and logistic regression models by implementing a new regularization method that incorporates correlation structures within the data. This method encourages a grouping effect where strongly correlated predictors tend to be in or out of the model together. See Tutz and Ulbricht (2009) <doi:10.1007/s11222-008-9088-5> and Algamal and Lee (2015) <doi:10.1016/j.eswa.2015.08.016>.

To improve estimation accuracy and stability in statistical modeling, catalytic prior distributions are employed, integrating observed data with synthetic data generated from a simpler model's predictive distribution. This approach enhances model robustness, stability, and flexibility in complex data scenarios. The catalytic prior distributions are introduced by Huang et al. (2020, <doi:10.1073/pnas.1920913117>), Li and Huang (2023, <doi:10.48550/arXiv.2312.01411>).

This package provides tools for creating and visualizing statistical process control charts. Control charts are used for monitoring measurement processes, such as those occurring in manufacturing. The objective is to monitor the history of such processes and flag outlying measurements: out-of-control signals. Montgomery, D. (2009, ISBN:978-0-470-16992-6) contains an extensive discussion of the methodology.

This package implements the Conditional Ordinal Stereotype Model for Incident-Level Comparison (COSMIC), a method for analyzing ordinal outcomes observed across multiple actors within shared events. The model uses a conditional likelihood to remove event-level confounding and estimate actor-specific propensities relative to their peers. Efficient computation is achieved via a dynamic programming algorithm for the Poisson-multinomial normalization term, enabling scalable estimation with Markov chain Monte Carlo. The package provides tools for data preparation, model fitting using Stan, and extraction of posterior summaries for comparative inference. Estimation of police officer propensity to escalate force is the primary motivation for the model. For more details see Ridgeway (2026) "A Conditional Ordinal Stereotype Model to Estimate Police Officersâ Propensity to Escalate Force" <doi:10.1080/01621459.2025.2597050>.

This package provides functions for building cognitive maps based on qualitative data. Inputs are textual sources (articles, transcription of qualitative interviews of agents,...). These sources have been coded using relations and are linked to (i) a table describing the variables (or concepts) used for the coding and (ii) a table describing the sources (typology of agents, ...). Main outputs are Individual Cognitive Maps (ICM), Social Cognitive Maps (all sources or group of sources) and a list of quotes linked to relations. This package is linked to the work done during the PhD of Frederic M. Vanwindekens (CRA-W / UCL) hold the 13 of May 2014 at University of Louvain in collaboration with the Walloon Agricultural Research Centre (project MIMOSA, MOERMAN fund).

This package implements an MCMC algorithm to estimate a hierarchical multinomial logit model with a normal heterogeneity distribution. The algorithm uses a hybrid Gibbs Sampler with a random walk metropolis step for the MNL coefficients for each unit. Dependent variable may be discrete or continuous. Independent variables may be discrete or continuous with optional order constraints. Means of the distribution of heterogeneity can optionally be modeled as a linear function of unit characteristics variables.

Clustering methods, which (if asked) can provide step-by-step explanations of the algorithms used, as described in Ezugwu et. al., (2022) <doi:10.1016/j.engappai.2022.104743>; and datasets to test them on, which highlight the strengths and weaknesses of each technique, as presented in the clustering section of scikit-learn (Pedregosa et al., 2011) <https://jmlr.csail.mit.edu/papers/v12/pedregosa11a.html>.

The theory of cooperative games with transferable utility offers useful insights into the way parties can share gains from cooperation and secure sustainable agreements, see e.g. one of the books by Chakravarty, Mitra and Sarkar (2015, ISBN:978-1107058798) or by Driessen (1988, ISBN:978-9027727299) for more details. A comprehensive set of tools for cooperative game theory with transferable utility is provided. Users can create special families of cooperative games, like e.g. bankruptcy games, cost sharing games and weighted voting games. There are functions to check various game properties and to compute five different set-valued solution concepts for cooperative games. A large number of point-valued solution concepts is available reflecting the diverse application areas of cooperative game theory. Some of these point-valued solution concepts can be used to analyze weighted voting games and measure the influence of individual voters within a voting body. There are routines for visualizing both set-valued and point-valued solutions in the case of three or four players.

This package provides functions for performing comparative cohort studies in an observational database in the Observational Medical Outcomes Partnership (OMOP) Common Data Model. Can extract all necessary data from a database. This implements large-scale propensity scores (LSPS) as described in Tian et al. (2018) <doi:10.1093/ije/dyy120>, using a large set of covariates, including for example all drugs, diagnoses, procedures, as well as age, comorbidity indexes, etc. Large scale regularized regression is used to fit the propensity and outcome models as described in Suchard et al. (2013) <doi:10.1145/2414416.2414791>. Functions are included for trimming, stratifying, (variable and fixed ratio) matching and weighting by propensity scores, as well as diagnostic functions, such as propensity score distribution plots and plots showing covariate balance before and after matching and/or trimming. Supported outcome models are (conditional) logistic regression, (conditional) Poisson regression, and (stratified) Cox regression. Also included are Kaplan-Meier plots that can adjust for the stratification or matching.

Identification of cardinal dates (begin, time of maximum, end of mass developments) in ecological time series using fitted Weibull functions.

Compute price indices using various Hedonic and multilateral methods, including Laspeyres, Paasche, Fisher, and HMTS (Hedonic Multilateral Time series re-estimation with splicing). The central function calculate_price_index() offers a unified interface for running these methods on structured datasets. This package is designed to support index construction workflows for real estate and other domains where quality-adjusted price comparisons over time are essential. The development of this package was funded by Eurostat and Statistics Netherlands (CBS), and carried out by Statistics Netherlands. The HMTS method implemented here is described in Ishaak, Ouwehand and Remøy (2024) <doi:10.1177/0282423X241246617>. For broader methodological context, see Eurostat (2013, ISBN:978-92-79-25984-5, <doi:10.2785/34007>).

Fits constrained groupwise additive index models and provides functions for inference and interpretation of these models. The method is described in Masselot, Chebana, Campagna, Lavigne, Ouarda, Gosselin (2022) "Constrained groupwise additive index models" <doi:10.1093/biostatistics/kxac023>.

This package provides a flexible tool for calculating carbon-equivalent emissions. Mostly using data from the UK Government's Greenhouse Gas Conversion Factors report <https://www.gov.uk/government/publications/greenhouse-gas-reporting-conversion-factors-2024>, it facilitates transparent emissions calculations for various sectors, including travel, accommodation, and clinical activities. The package is designed for easy integration into R workflows, with additional support for shiny applications and community-driven extensions.

This package provides a collection of tools to easily analyze clinical data, including functions for correlation analysis, and statistical testing. The package facilitates the integration of clinical metadata with other omics layers, enabling exploration of quantitative variables. It also includes the utility for frequency matching samples across a dataset based on patient variables.

Includes the 100 datasets simulated by Congreve and Lamsdell (2016) <doi:10.1111/pala.12236>, and analyses of the partition and quartet distance of reconstructed trees from the generative tree, as analysed by Smith (2019) <doi:10.1098/rsbl.2018.0632>.

Offers tools to identify the climate analogues of reference polygons and quantifies their transformation under future climate change scenarios. Approaches described in Mingarro and Lobo (2018) <doi:10.32800/abc.2018.41.0333> and Mingarro and Lobo (2022) <doi:10.1017/S037689292100014X>.

Joint distribution of number of crossings and the longest run in a series of independent Bernoulli trials. The computations uses an iterative procedure where computations are based on results from shorter series. The procedure conditions on the start value and partitions by further conditioning on the position of the first crossing (or none).

Perform the functional modeling methods of Huang and Wang (2018) <doi:10.1111/biom.12741> to accommodate dependent error in covariates of the proportional hazards model. The adopted measurement error model has minimal assumptions on the dependence structure, and an instrumental variable is supposed to be available.

This package provides functions for predictor pruning using association-based and model-based approaches. Includes corrPrune() for fast correlation-based pruning, modelPrune() for VIF-based regression pruning, and exact graph-theoretic algorithms (Eppsteinâ Löfflerâ Strash, Bronâ Kerbosch) for exhaustive subset enumeration. Supports linear models, GLMs, and mixed models ('lme4', glmmTMB').

This package implements a method for identifying and removing the cell-cycle effect from scRNA-Seq data. The description of the method is in Barron M. and Li J. (2016) <doi:10.1038/srep33892>. Identifying and removing the cell-cycle effect from single-cell RNA-Sequencing data. Submitted. Different from previous methods, ccRemover implements a mechanism that formally tests whether a component is cell-cycle related or not, and thus while it often thoroughly removes the cell-cycle effect, it preserves other features/signals of interest in the data.

This package provides a collection of cardiovascular research datasets and analytical tools, including methods for cardiovascular procedural data, such as electrocardiography, echocardiography, and catheterization data. Additional methods exist for analysis of procedural billing codes.

This package provides a method for pattern discovery in weighted graphs as outlined in Thistlethwaite et al. (2021) <doi:10.1371/journal.pcbi.1008550>. Two use cases are achieved: 1) Given a weighted graph and a subset of its nodes, do the nodes show significant connectedness? 2) Given a weighted graph and two subsets of its nodes, are the subsets close neighbors or distant?