Add-on to the airGR package which provides the tools to assimilate observed discharges in daily GR hydrological models. The package consists in two functions allowing to perform the assimilation of observed discharges via the Ensemble Kalman filter or the Particle filter as described in Piazzi et al. (2021) <doi:10.1029/2020WR028390>.

This package provides a powerful tool for automating the early detection of disease outbreaks in time series data. aeddo employs advanced statistical methods, including hierarchical models, in an innovative manner to effectively characterize outbreak signals. It is particularly useful for epidemiologists, public health professionals, and researchers seeking to identify and respond to disease outbreaks in a timely fashion. For a detailed reference on hierarchical models, consult Henrik Madsen and Poul Thyregod's book (2011), ISBN: 9781420091557.

This package provides methods for processing corporate balance sheets with a focus on the Brazilian reporting format. Includes data standardization, classification by accounting categories, and aggregation of values. Supports accounting and financial analyses of companies, improving efficiency and ensuring reproducibility of empirical studies.

Adversarial random forests (ARFs) recursively partition data into fully factorized leaves, where features are jointly independent. The procedure is iterative, with alternating rounds of generation and discrimination. Data becomes increasingly realistic at each round, until original and synthetic samples can no longer be reliably distinguished. This is useful for several unsupervised learning tasks, such as density estimation and data synthesis. Methods for both are implemented in this package. ARFs naturally handle unstructured data with mixed continuous and categorical covariates. They inherit many of the benefits of random forests, including speed, flexibility, and solid performance with default parameters. For details, see Watson et al. (2023) <https://proceedings.mlr.press/v206/watson23a.html>.

This package provides functions to process minute level actigraphy-measured activity counts data and extract commonly used physical activity volume and fragmentation metrics.

This package provides methods for fitting identity-link GLMs and GAMs to discrete data, using EM-type algorithms with more stable convergence properties than standard methods.

Fit various smoothing spline models. Includes an ssr() function for smoothing spline regression, an nnr() function for nonparametric nonlinear regression, an snr() function for semiparametric nonlinear regression, an slm() function for semiparametric linear mixed-effects models, and an snm() function for semiparametric nonlinear mixed-effects models. See Wang (2011) <doi:10.1201/b10954> for an overview.

An interactive document on the topic of one-way and two-way analysis of variance using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://kartikeyab.shinyapps.io/ANOVAShiny/>.

This package provides new_partialised() and new_composed(), which extend partial() and compose() functions of purrr to make it easier to extract and replace arguments and functions. It also has additional adverbial functions.

This package provides a collection of several pharmacovigilance signal detection methods based on adaptive lasso. Additional lasso-based and propensity score-based signal detection approaches are also supplied. See Courtois et al <doi:10.1186/s12874-021-01450-3>.

This package provides scalable generalized linear and mixed effects models tailored for sequence count data analysis (e.g., analysis of 16S or RNA-seq data). Uses Dirichlet-multinomial sampling to quantify uncertainty in relative abundance or relative expression conditioned on observed count data. Implements scale models as a generalization of normalizations which account for uncertainty in scale (e.g., total abundances) as described in Nixon et al. (2025) <doi:10.1186/s13059-025-03609-3> and McGovern et al. (2025) <doi:10.1101/2025.08.05.668734>.

This package provides functions to simplify and standardise antimicrobial resistance (AMR) data analysis and to work with microbial and antimicrobial properties by using evidence-based methods, as described in <doi:10.18637/jss.v104.i03>.

This package contains tools to fit the additive hazards model to data from a cohort, random sampling, two-phase Bernoulli sampling and two-phase finite population sampling, as well as calibration tool to incorporate phase I auxiliary information into the two-phase data model fitting. This package provides regression parameter estimates and their model-based and robust standard errors. It also offers tools to make prediction of individual specific hazards.

This package performs approximate unconditional and permutation testing for 2x2 contingency tables. Motivated by testing for disease association with rare genetic variants in case-control studies. When variants are extremely rare, these tests give better control of Type I error than standard tests.

Automated methods to assemble population PK (pharmacokinetic) and PKPD (pharmacodynamic) datasets for analysis in NONMEM (non-linear mixed effects modeling) by Bauer (2019) <doi:10.1002/psp4.12404>. The package includes functions to build datasets from SDTM (study data tabulation module) <https://www.cdisc.org/standards/foundational/sdtm>, ADaM (analysis dataset module) <https://www.cdisc.org/standards/foundational/adam>, or other dataset formats. The package will combine population datasets, add covariates, and create documentation to support regulatory submission and internal communication.

Extremely efficient toolkit for solving the best subset selection problem <https://www.jmlr.org/papers/v23/21-1060.html>. This package is its R interface. The package implements and generalizes algorithms designed in <doi:10.1073/pnas.2014241117> that exploits a novel sequencing-and-splicing technique to guarantee exact support recovery and globally optimal solution in polynomial times for linear model. It also supports best subset selection for logistic regression, Poisson regression, Cox proportional hazard model, Gamma regression, multiple-response regression, multinomial logistic regression, ordinal regression, Ising model reconstruction <doi:10.1080/01621459.2025.2571245>, (sequential) principal component analysis, and robust principal component analysis. The other valuable features such as the best subset of group selection <doi:10.1287/ijoc.2022.1241> and sure independence screening <doi:10.1111/j.1467-9868.2008.00674.x> are also provided.

Automate the modelling of age-structured population data using survey data, grid population estimates and urban-rural extents.

Describes a series first. After that does time series analysis using one hybrid model and two specially structured Machine Learning (ML) (Artificial Neural Network or ANN and Support Vector Regression or SVR) models. More information can be obtained from Paul and Garai (2022) <doi:10.1007/s41096-022-00128-3>.

Epidemiological population dynamics models traditionally define a pathogen's virulence as the increase in the per capita rate of mortality of infected hosts due to infection. This package provides functions allowing virulence to be estimated by maximum likelihood techniques. The approach is based on the analysis of relative survival comparing survival in matching cohorts of infected vs. uninfected hosts (Agnew 2019) <doi:10.1101/530709>.

This package creates all leave-one-out models and produces predictions for test samples.

Estimate the linear and nonlinear autoregressive distributed lag (ARDL & NARDL) models and the corresponding error correction models, and test for longrun and short-run asymmetric. The general-to-specific approach is also available in estimating the ARDL and NARDL models. The Pesaran, Shin & Smith (2001) (<doi:10.1002/jae.616>) bounds test for level relationships is also provided. The ardl.nardl package also performs short-run and longrun symmetric restrictions available at Shin et al. (2014) <doi:10.1007/978-1-4899-8008-3_9> and their corresponding tests.

Automatically selects and runs the most appropriate statistical test for your data, returning clear, easy-to-read results. Ideal for all experience levels.

This package provides a stacking solution for modeling imbalanced and severely skewed data. It automates the process of building homogeneous or heterogeneous stacked ensemble models by selecting "best" models according to different criteria. In doing so, it strategically searches for and selects diverse, high-performing base-learners to construct ensemble models optimized for skewed data. This package is particularly useful for addressing class imbalance in datasets, ensuring robust and effective model outcomes through advanced ensemble strategies which aim to stabilize the model, reduce its overfitting, and further improve its generalizability.

Experience studies are used by actuaries to explore historical experience across blocks of business and to inform assumption setting activities. This package provides functions for preparing data, creating studies, visualizing results, and beginning assumption development. Experience study methods, including exposure calculations, are described in: Atkinson & McGarry (2016) "Experience Study Calculations" <https://www.soa.org/49378a/globalassets/assets/files/research/experience-study-calculations.pdf>. The limited fluctuation credibility method used by the exp_stats() function is described in: Herzog (1999, ISBN:1-56698-374-6) "Introduction to Credibility Theory".