An interactive document on the topic of cluster analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://analyticmodels.shinyapps.io/ClusterAnalysis/>.

Calculates predictions from generalized estimating equations and internally cross-validates them using the logarithmic, quadratic and spherical proper scoring rules; Kung-Yee Liang and Scott L. Zeger (1986) <doi:10.1093/biomet/73.1.13>.

This package provides a spatially-aware cell clustering algorithm is provided with cluster significance assessment. It comprises four key modules: spatially-aware cell-gene co-embedding, cell clustering, signature gene identification, and cluster significant assessment. More details can be referred to Peng Xie, et al. (2025) <doi:10.1016/j.cell.2025.05.035>.

Customized training is a simple technique for transductive learning, when the test covariates are known at the time of training. The method identifies a subset of the training set to serve as the training set for each of a few identified subsets in the training set. This package implements customized training for the glmnet() and cv.glmnet() functions.

Small package to clean the R console and the R environment with the call of just one function.

With the development of new cross-cultural methods this package is intended to combine multiple functions automating and simplifying functions providing a unified analysis approach for commonly employed methods.

Core functions for simulating quantities of interest from generalised linear models (GLM). This package will form the backbone of a series of other packages that improve the interpretation of GLM estimates.

This package contains selected variables from the time series profiles for statistical areas level 2 from the 2006, 2011, and 2016 censuses of population and housing, Australia. Also provides methods for viewing the questions asked for convenience during analysis.

The reliability of assessment tools is a crucial aspect of monitoring student performance in various educational settings. It ensures that the assessment outcomes accurately reflect a student's true level of performance. However, when assessments are combined, determining composite reliability can be challenging, especially for naturalistic and unbalanced datasets. This package provides an easy-to-use solution for calculating composite reliability for different assessment types. It allows for the inclusion of weight per assessment type and produces extensive G- and D-study results with graphical interpretations. Overall, our approach enhances the reliability of composite assessments, making it suitable for various education contexts.

Define the output format of rmarkdown files with shared output yaml frontmatter content. Rather than modifying a shared yaml file, use integers to easily switch output formats for rmarkdown files.

Implementations of canonical associative learning models, with tools to run experiment simulations, estimate model parameters, and compare model representations. Experiments and results are represented using S4 classes and methods.

This package provides object-oriented database management tools for working with large datasets across multiple database systems. Features include robust connection management for SQL Server and PostgreSQL databases, advanced table operations with bulk data loading and upsert functionality, comprehensive data validation through customizable field type and content validators, efficient index management, and cross-database compatibility. Designed for high-performance data operations in surveillance systems and large-scale data processing workflows.

Compare color palettes with simulations of color vision deficiencies - deuteranopia, protanopia, and tritanopia. It includes calculation of distances between colors, and creating summaries of differences between a color palette and simulations of color vision deficiencies. This work was inspired by the blog post at <https://www.datawrapper.de/blog/colorblind-check>.

Helps automate Quarto website creation for small academic groups. Builds a database-like structure of people, projects and publications, linking them together with a string-based ID system. Then, provides functions to automate production of clean markdown for these structures, and in-built CSS formatting using CSS flexbox.

Causal Inference Assistance (CIA) for performing causal inference within the structural causal modelling framework. Structure learning is performed using partition Markov chain Monte Carlo (Kuipers & Moffa, 2017) and several additional functions have been added to help with causal inference. Kuipers and Moffa (2017) <doi:10.1080/01621459.2015.1133426>.

Conditioned Latin hypercube sampling, as published by Minasny and McBratney (2006) <DOI:10.1016/j.cageo.2005.12.009>. This method proposes to stratify sampling in presence of ancillary data. An extension of this method, which propose to associate a cost to each individual and take it into account during the optimisation process, is also proposed (Roudier et al., 2012, <DOI:10.1201/b12728>).

Non-linear/linear hybrid method for batch-effect correction that uses Mutual Nearest Neighbors (MNNs) to identify similar cells between datasets. Reference: Loza M. et al. (NAR Genomics and Bioinformatics, 2020) <doi:10.1093/nargab/lqac022>.

Implementing seven Covariate-Adaptive Randomization to assign patients to two treatments. Three of these procedures can also accommodate quantitative and mixed covariates. Given a set of covariates, the user can generate a single sequence of allocations or replicate the design multiple times by simulating the patients covariate profiles. At the end, an extensive assessment of the performance of the randomization procedures is provided, calculating several imbalance measures. See Baldi Antognini A, Frieri R, Zagoraiou M and Novelli M (2022) <doi:10.1007/s00362-022-01381-1> for details.

Obtain coordinate system metadata from various data formats. There are functions to extract a CRS (coordinate reference system, <https://en.wikipedia.org/wiki/Spatial_reference_system>) in EPSG (European Petroleum Survey Group, <http://www.epsg.org/>), PROJ4 <https://proj.org/>, or WKT2 (Well-Known Text 2, <http://docs.opengeospatial.org/is/12-063r5/12-063r5.html>) forms. This is purely for getting simple metadata from in-memory formats, please use other tools for out of memory data sources.

This package provides functions for visualizing, animating, solving and analyzing the Rubik's cube. Includes data structures for solvable and unsolvable cubes, random moves and random state scrambles and cubes, 3D displays and animations using OpenGL', patterned cube generation, and lightweight solvers. See Rokicki, T. (2008) <arXiv:0803.3435> for the Kociemba solver.

This package performs biomedical named entity recognition, Unified Medical Language System (UMLS) concept mapping, and negation detection using the Python spaCy', scispaCy', and medspaCy packages, and transforms extracted data into a wide format for inclusion in machine learning models. The development of the scispaCy package is described by Neumann (2019) <doi:10.18653/v1/W19-5034>. The medspacy package uses ConText', an algorithm for determining the context of clinical statements described by Harkema (2009) <doi:10.1016/j.jbi.2009.05.002>. Clinspacy also supports entity embeddings from scispaCy and UMLS cui2vec concept embeddings developed by Beam (2018) <arXiv:1804.01486>.

Calculate the R-squared, aka explained randomness, based on the partial likelihood ratio statistic under the Cox Proportional Hazard model [J O'Quigley, R Xu, J Stare (2005) <doi:10.1002/sim.1946>].

Although many software tools can perform meta-analyses on genetic case-control data, none of these apply to combined case-control and family-based (TDT) studies. This package conducts fixed-effects (with inverse variance weighting) and random-effects [DerSimonian and Laird (1986) <DOI:10.1016/0197-2456(86)90046-2>] meta-analyses on combined genetic data. Specifically, this package implements a fixed-effects model [Kazeem and Farrall (2005) <DOI:10.1046/j.1529-8817.2005.00156.x>] and a random-effects model [Nicodemus (2008) <DOI:10.1186/1471-2105-9-130>] for combined studies.

This package provides functions supporting the common needs of packages ChemoSpec and ChemoSpec2D'.