This package provides functions for making contour plots. The contour plot can be created from grid data, a function, or a data set. If non-grid data is given, then a Gaussian process is fit to the data and used to create the contour plot.

Linear or nonlinear cross-lagged panel model can be built from input data. Users can choose the appropriate method from three methods for constructing nonlinear cross lagged models. These three methods include polynomial regression, generalized additive model and generalized linear mixed model.In addition, a function for determining linear relationships is provided. Relevant knowledge of cross lagged models can be learned through the paper by Fredrik Falkenström (2024) <doi:10.1016/j.cpr.2024.102435> and the paper by A Gasparrini (2010) <doi:10.1002/sim.3940>.

This package provides a collection of functions for modeling fissile material operations in nuclear facilities, based on Zywiec et al (2021) <doi:10.1016/j.ress.2020.107322>.

Clustering categorical sequences by means of finite mixtures with Markov model components is the main utility of ClickClust. The package also allows detecting blocks of equivalent states by forward and backward state selection procedures.

This package implements higher order likelihood-based inference for logistic and loglinear models.

This package provides tools for advanced analysis of continuous glucose monitoring (CGM) time-series, implementing GRID (Glucose Rate Increase Detector) and GRID-based algorithms for postprandial peak detection, and detection of hypoglycemic and hyperglycemic episodes (Levels 1/2/Extended) aligned with international consensus CGM metrics. Core algorithms are implemented in optimized C++ using Rcpp to provide accurate and fast analysis on large datasets.

This package contains the R functions needed to perform Cluster-Of-Clusters Analysis (COCA) and Consensus Clustering (CC). For further details please see Cabassi and Kirk (2020) <doi:10.1093/bioinformatics/btaa593>.

This package provides functions to create contour-enhanced forest plots for meta-analysis, supporting binary outcomes (e.g., odds ratios, risk ratios), continuous outcomes (e.g., correlations), and prevalence estimates. Includes options for prediction intervals, customized colors, study labeling, and contour shading to highlight regions of statistical significance. Based on metafor and ggplot2'.

This package provides measures of effect sizes for summarized continuous variables as well as diagnostic accuracy statistics for 2x2 table data. Includes functions for Cohen's d, robust effect size, Cohen's q, partial eta-squared, coefficient of variation, odds ratio, likelihood ratios, sensitivity, specificity, positive and negative predictive values, Youden index, number needed to treat, number needed to diagnose, and predictive summary index.

This package implements the convex clustering through majorization-minimization (CCMM) algorithm described in Touw, Groenen, and Terada (2022) <doi:10.48550/arXiv.2211.01877> to perform minimization of the convex clustering loss function.

An engine for stochastic cellular automata. It provides a high-level interface to declare a model, which can then be simulated by various backends (Genin et al. (2023) <doi:10.1101/2023.11.08.566206>).

This package provides a programmatic interface to the Chromosome Counts Database (<https://ccdb.tau.ac.il/>), Rice et al. (2014) <doi:10.1111/nph.13191>. This package is part of the ROpenSci suite (<https://ropensci.org>).

Implementation of case-control data analysis using likelihood ratio approaches and logistic regression for the classification of variants of uncertain significance (VUS) in breast, ovarian, or custom cancer susceptibility genes.

Typical morphological profiling datasets have millions of cells and hundreds of features per cell. When working with this data, you must clean the data, normalize the features to make them comparable across experiments, transform the features, select features based on their quality, and aggregate the single-cell data, if needed. cytominer makes these steps fast and easy. Methods used in practice in the field are discussed in Caicedo (2017) <doi:10.1038/nmeth.4397>. An overview of the field is presented in Caicedo (2016) <doi:10.1016/j.copbio.2016.04.003>.

Compare double-precision floating point vectors using relative differences. All equality operations are calculated using cpp11'.

Perceptually uniform palettes for commonly used variables in oceanography as functions taking an integer and producing character vectors of colours. See Thyng, K.M., Greene, C.A., Hetland, R.D., Zimmerle, H.M. and S.F. DiMarco (2016) <doi:10.5670/oceanog.2016.66> for the guidelines adhered to when creating the palettes.

Solves multivariate least squares (MLS) problems subject to constraints on the coefficients, e.g., non-negativity, orthogonality, equality, inequality, monotonicity, unimodality, smoothness, etc. Includes flexible functions for solving MLS problems subject to user-specified equality and/or inequality constraints, as well as a wrapper function that implements 24 common constraint options. Also does k-fold or generalized cross-validation to tune constraint options for MLS problems. See ten Berge (1993, ISBN:9789066950832) for an overview of MLS problems, and see Goldfarb and Idnani (1983) <doi:10.1007/BF02591962> for a discussion of the underlying quadratic programming algorithm.

This package provides a uniform statistical inferential tool in making individualized treatment decisions, which implements the methods of Ma et al. (2017)<DOI:10.1177/0962280214541724> and Guo et al. (2021)<DOI:10.1080/01621459.2020.1865167>. It uses a flexible semiparametric modeling strategy for heterogeneous treatment effect estimation in high-dimensional settings and can gave valid confidence bands. Based on it, one can find the subgroups of patients that benefit from each treatment, thereby making individualized treatment selection.

This package provides functions for reading in and manipulating CRU TS3.21: Climatic Research Unit (CRU) Time-Series (TS) Version 3.21 data.

This package provides an expectation maximization (EM) algorithm to fit a mixture of continuous time Markov models for use with clickstream or other sequence type data. Gallaugher, M.P.B and McNicholas, P.D. (2018) <arXiv:1802.04849>.

Finds a low-dimensional embedding of high-dimensional data, conditioning on available manifold information.

The Satellite Application Facility on Climate Monitoring (CM SAF) is a ground segment of the European Organization for the Exploitation of Meteorological Satellites (EUMETSAT) and one of EUMETSATs Satellite Application Facilities. The CM SAF contributes to the sustainable monitoring of the climate system by providing essential climate variables related to the energy and water cycle of the atmosphere (<https://www.cmsaf.eu>). It is a joint cooperation of eight National Meteorological and Hydrological Services. The cmsafvis R-package provides a collection of R-operators for the analysis and visualization of CM SAF NetCDF data. CM SAF climate data records are provided for free via (<https://wui.cmsaf.eu/safira>). Detailed information and test data are provided on the CM SAF webpage (<http://www.cmsaf.eu/R_toolbox>).

Automated method for doublet detection in flow or mass cytometry data, based on simulating doublets and finding events whose protein expression patterns are similar to the simulated doublets.

Impute the survival times for censored observations based on their conditional survival distributions derived from the Kaplan-Meier estimator. CondiS can replace the censored observations with the best approximations from the statistical model, allowing for direct application of machine learning-based methods. When covariates are available, CondiS is extended by incorporating the covariate information through machine learning-based regression modeling ('CondiS_X'), which can further improve the imputed survival time.