Diagnostic and prognostic models are typically evaluated with measures of accuracy that do not address clinical consequences. Decision-analytic techniques allow assessment of clinical outcomes, but often require collection of additional information may be cumbersome to apply to models that yield a continuous result. Decision curve analysis is a method for evaluating and comparing prediction models that incorporates clinical consequences, requires only the data set on which the models are tested, and can be applied to models that have either continuous or dichotomous results. See the following references for details on the methods: Vickers (2006) <doi:10.1177/0272989X06295361>, Vickers (2008) <doi:10.1186/1472-6947-8-53>, and Pfeiffer (2020) <doi:10.1002/bimj.201800240>.

An open, multi-algorithmic pipeline for easy, fast and efficient analysis of cellular sub-populations and the molecular signatures that characterize them. The pipeline consists of four successive steps: data pre-processing, cellular clustering with pseudo-temporal ordering, defining differential expressed genes and biomarker identification. More details on Ghannoum et. al. (2021) <doi:10.3390/ijms22031399>. This package implements extensions of the work published by Ghannoum et. al. (2019) <doi:10.1101/700989>.

This package provides a set of tools for empirical analysis of diversity (a number and frequency of different types in a population) and similarity (a number and frequency of shared types in two populations) in biological or ecological systems.

This package implements fast Monte Carlo simulations for goodness-of-fit (GOF) tests for discrete distributions. This includes tests based on the Chi-squared statistic, the log-likelihood-ratio (G^2) statistic, the Freeman-Tukey (Hellinger-distance) statistic, the Kolmogorov-Smirnov statistic, the Cramer-von Mises statistic as described in Choulakian, Lockhart and Stephens (1994) <doi:10.2307/3315828>, and the root-mean-square statistic, see Perkins, Tygert, and Ward (2011) <doi:10.1016/j.amc.2011.03.124>.

This package provides a wrapper on top of the Domino Data Python SDK library. It lets you query and access Domino Data Sources directly from your R environment. Under the hood, Domino Data R SDK leverages the API provided by the Domino Data Python SDK', which must be installed as a prerequisite. Domino is a platform that makes it easy to run your code on scalable hardware, with integrated version control and collaboration features designed for analytical workflows. See <https://docs.dominodatalab.com/en/latest/api_guide/140b48/domino-data-api> for more information.

This package provides a framework for the replicable removal of personally identifiable data (PID) in data sets. The package implements a suite of methods to suit different data types based on the suggestions of Garfinkel (2015) <doi:10.6028/NIST.IR.8053> and the ICO "Guidelines on Anonymization" (2012) <https://ico.org.uk/media/1061/anonymisation-code.pdf>.

This package provides a comprehensive data validation package that allows comparing datasets using configurable validation rules defined in YAML files. Built on top of the pointblank package for robust data validation, it supports exact matching, tolerance-based numeric comparisons, text normalization, and row count validation.

Access the Google Data Commons API V2 <https://docs.datacommons.org/api/rest/v2/>. Data Commons provides programmatic access to statistical and demographic data from dozens of sources organized in a knowledge graph.

Gaussian mixture modeling of one- and two-dimensional data, provided in original or binned form, with an option to estimate the number of model components. The method uses Gaussian Mixture Models (GMM) with initial parameters determined by a dynamic programming algorithm, leading to stable and reproducible model fitting. For more details see Zyla, J., Szumala, K., Polanski, A., Polanska, J., & Marczyk, M. (2026) <doi:10.1016/j.jocs.2026.102811>.

Data depth concept offers a variety of powerful and user friendly tools for robust exploration and inference for multivariate data. The offered techniques may be successfully used in cases of lack of our knowledge on parametric models generating data due to their nature. The package consist of among others implementations of several data depth techniques involving multivariate quantile-quantile plots, multivariate scatter estimators, multivariate Wilcoxon tests and robust regressions.

Comparison of the accuracy of two binary diagnostic tests in a "paired" study design, i.e. when each test is applied to each subject in the study.

Computes discrete fast Fourier transform of river discharge data and the derived metrics. The methods are described in J. L. Sabo, D. M. Post (2008) <doi:10.1890/06-1340.1> and J. L. Sabo, A. Ruhi, G. W. Holtgrieve, V. Elliott, M. E. Arias, P. B. Ngor, T. A. Räsänsen, S. Nam (2017) <doi:10.1126/science.aao1053>.

Three global value chain (GVC) decompositions are implemented. The Leontief decomposition derives the value added origin of exports by country and industry as in Hummels, Ishii and Yi (2001). The Koopman, Wang and Wei (2014) decomposition splits country-level exports into 9 value added components, and the Wang, Wei and Zhu (2013) decomposition splits bilateral exports into 16 value added components. Various GVC indicators based on these decompositions are computed in the complimentary gvc package. --- References: --- Hummels, D., Ishii, J., & Yi, K. M. (2001). The nature and growth of vertical specialization in world trade. Journal of international Economics, 54(1), 75-96. Koopman, R., Wang, Z., & Wei, S. J. (2014). Tracing value-added and double counting in gross exports. American Economic Review, 104(2), 459-94. Wang, Z., Wei, S. J., & Zhu, K. (2013). Quantifying international production sharing at the bilateral and sector levels (No. w19677). National Bureau of Economic Research.

The ts objects in R are managed using a very specific date format (in the form c(2022, 9) for September 2022 or c(2021, 2) for the second quarter of 2021, depending on the frequency, for example). We focus solely on monthly and quarterly series to manage the dates of ts objects. The general idea is to offer a set of functions to manage this date format without it being too restrictive or too imprecise depending on the rounding. This is a compromise between simplicity, precision and use of the basic stats functions for creating and managing time series (ts(), window()). Les objets ts en R sont gérés par un format de date très particulier (sous la forme c(2022, 9) pour septembre 2022 ou c(2021, 2) pour le deuxième trimestre 2021 selon la fréquence par exemple). On se concentre uniquement sur les séries mensuelles et trimestrielles pour gérer les dates des objets ts. Lidée générale est de proposer un ensemble de fonctions pour gérer ce format de date sans que ce soit trop contraignant ou trop imprécis selon les arrondis. Cest un compromis entre simplicité, précision et utilisation des fonctions du package stats de création et de gestion des séries temporelles (ts(), window()).

To create demographic table with simple summary statistics, with optional comparison(s) over one or more groups.

Assists in finding the most suitable thread count for the various data.table routines that support parallel processing.

Provide a Dens-based method for estimating functional connection in large scale brain networks using partial correlation.

Clustered or multilevel data structures are common in the assessment of differential item functioning (DIF), particularly in the context of large-scale assessment programs. This package allows users to implement extensions of the Mantel-Haenszel DIF detection procedures in the presence of multilevel data based on the work of Begg (1999) <doi:10.1111/j.0006-341X.1999.00302.x>, Begg & Paykin (2001) <doi:10.1080/00949650108812115>, and French & Finch (2013) <doi:10.1177/0013164412472341>.

Analyze and visualize the rhythmic behavior of animals using the degree of functional coupling (See Scheibe (1999) <doi:10.1076/brhm.30.2.216.1420>), compute and visualize harmonic power, actograms, average activity and diurnality index.

Researchers can characterize and learn about the properties of research designs before implementation using `DeclareDesign`. Ex ante declaration and diagnosis of designs can help researchers clarify the strengths and limitations of their designs and to improve their properties, and can help readers evaluate a research strategy prior to implementation and without access to results. It can also make it easier for designs to be shared, replicated, and critiqued.

This package provides a set of tools for relational and event analysis, including two- and one-mode network brokerage and structural measures, and helper functions optimized for relational event analysis with large datasets, including creating relational risk sets, computing network statistics, estimating relational event models, and simulating relational event sequences. For more information on relational event models, see Butts (2008) <doi:10.1111/j.1467-9531.2008.00203.x>, Lerner and Lomi (2020) <doi:10.1017/nws.2019.57>, Bianchi et al. (2024) <doi:10.1146/annurev-statistics-040722-060248>, and Butts et al. (2023) <doi:10.1017/nws.2023.9>. In terms of the structural measures in this package, see Leal (2025) <doi:10.1177/00491241251322517>, Burchard and Cornwell (2018) <doi:10.1016/j.socnet.2018.04.001>, and Fujimoto et al. (2018) <doi:10.1017/nws.2018.11>. This package was developed with support from the National Science Foundationâ s (NSF) Human Networks and Data Science Program (HNDS) under award number 2241536 (PI: Diego F. Leal). Any opinions, findings, and conclusions, or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the NSF.

This package provides tools for detecting, decomposing, and stress-testing temporal drift in repeated binary decision systems. Complements the decisionpaths package by shifting focus from path construction to system-level change over time. Implements five core analytic modules: (1) prevalence drift â did the overall decision rate change over time?; (2) transition drift â did the probability of switching or persisting change?; (3) entropy and stability trends â did path complexity evolve?; (4) group-differential drift â did the system drift differently across subgroups?; (5) change-point and regime-shift detection â did the system change abruptly after a policy or model update? Additionally provides a robustness module for testing stability of drift conclusions across analytic choices, and a sensitivity module for probing vulnerability to data problems including missingness, miscoding, and threshold shifts. Defines four original drift indices: the Decision Drift Index (DDI), Transition Drift Index (TDI), Group Differential Drift (GDD), and Cumulative Drift Burden (CDB). Applications include algorithmic audit, AI governance, education, health, and organisational research.

This package implements an anomaly detection algorithm based on mutual reachability minimum spanning trees: deadwood trims protruding tree segments and marks small debris as outliers; see Gagolewski (2026) <https://deadwood.gagolewski.com/>. More precisely, the use of a mutual reachability distance pulls peripheral points farther away from each other. Tree edges with weights beyond the detected elbow point are removed. All the resulting connected components whose sizes are smaller than a given threshold are deemed anomalous. The Python version of deadwood is available via PyPI'.

This package implements the distribution-free goodness-of-fit regression test for the mean structure of parametric models introduced in Khmaladze (2021) <doi:10.1007/s10463-021-00786-3>. The test is implemented for general functions with minimal distributional assumptions as well as common models (e.g., lm, glm) with the usual assumptions.