This package contains a single function dclust() for divisive hierarchical clustering based on recursive k-means partitioning (k = 2). Useful for clustering large datasets where computation of a n x n distance matrix is not feasible (e.g. n > 10,000 records). For further information see Steinbach, Karypis and Kumar (2000) <http://glaros.dtc.umn.edu/gkhome/fetch/papers/docclusterKDDTMW00.pdf>.

Function to create forest plots. Functions to use posterior samples from Bayesian bivariate meta-analysis model, Bayesian hierarchical summary receiver operating characteristic (HSROC) meta-analysis model or Bayesian latent class (LC) meta-analysis model to create Summary Receiver Operating Characteristic (SROC) plots using methods described by Harbord et al (2007)<doi:10.1093/biostatistics/kxl004>.

Allows to visualize high-density electroencephalography (HD-EEG) data through interactive plots and animations, enabling exploratory and communicative analysis of temporal-spatial brain signals. Funder: Masaryk University (Grant No. MUNI/A/1457/2023).

This package performs Bayesian model averaging for capture-recapture. This includes code to stratify records, check the strata for suitable overlap to be used for capture-recapture, and some functions to plot the estimated population size.

This package provides a single function that supports the installation of all packages belonging to the dartRverse'. The dartRverse is a set of packages that work together to analyse SNP (single nuclear polymorphism) data. All packages aim to have a similar look and feel and are based on the same type of data structure ('genlight'), with additional metadata for loci and individuals (samples). For more information visit the GitHub pages <https://github.com/green-striped-gecko/dartRverse>.

This package provides documentation in form of a common vignette to packages distr', distrEx', distrMod', distrSim', distrTEst', distrTeach', and distrEllipse'.

This package performs the identification of differential risk hotspots (Briz-Redon et al. 2019) <doi:10.1016/j.aap.2019.105278> along a linear network. Given a marked point pattern lying on the linear network, the method implemented uses a network-constrained version of kernel density estimation (McSwiggan et al. 2017) <doi:10.1111/sjos.12255> to approximate the probability of occurrence across space for the type of event specified by the user through the marks of the pattern (Kelsall and Diggle 1995) <doi:10.2307/3318678>. The goal is to detect microzones of the linear network where the type of event indicated by the user is overrepresented.

This package performs detection of Differential Item Functioning using the method DIFboost as proposed by Schauberger and Tutz (2016) <doi:10.1111/bmsp.12060>.

This package provides the ability to display something analogous to Python's docstrings within R. By allowing the user to document their functions as comments at the beginning of their function without requiring putting the function into a package we allow more users to easily provide documentation for their functions. The documentation can be viewed just like any other help files for functions provided by packages as well.

Probability mass function, distribution function, quantile function, random generation and estimation for the skew discrete Laplace distributions.

The disparity filter algorithm is a network reduction technique to identify the backbone structure of a weighted network without destroying its multi-scale nature. The algorithm is documented in M. Angeles Serrano, Marian Boguna and Alessandro Vespignani in "Extracting the multiscale backbone of complex weighted networks", Proceedings of the National Academy of Sciences 106 (16), 2009. This implementation of the algorithm supports both directed and undirected networks.

This package performs calculations with tree taper (or stem profile) equations, including model fitting. The package implements the methods from Garcà a, O. (2015) "Dynamic modelling of tree form" <http://mcfns.net/index.php/Journal/article/view/MCFNS7.1_2>. The models are parsimonious, describe well the tree bole shape over its full length, and are consistent with wood formation mechanisms through time.

Tissue-specific enrichment analysis to assess lists of candidate genes or RNA-Seq expression profiles. Pei G., Dai Y., Zhao Z. Jia P. (2019) deTS: Tissue-Specific Enrichment Analysis to decode tissue specificity. Bioinformatics, In submission.

Preferred methods for common analytical tasks that are undertaken across the Department, including number formatting, project templates and curated reference data.

This package provides a wide collection of univariate discrete data sets from various applied domains related to distribution theory. The functions allow quick, easy, and efficient access to 100 univariate discrete data sets. The data are related to different applied domains, including medical, reliability analysis, engineering, manufacturing, occupational safety, geological sciences, terrorism, psychology, agriculture, environmental sciences, road traffic accidents, demography, actuarial science, law, and justice. The documentation, along with associated references for further details and uses, is presented.

This tool is for parsing public drug databases such as DrugBank XML database <https://go.drugbank.com/>. The parsed data are then returned in a proper R object called dvobject'.

Secant acceleration applied to derivative-free Spectral Residual Methods for solving large-scale nonlinear systems of equations. The main reference follows: E. G. Birgin and J. M. Martinez (2022) <doi:10.1137/20M1388024>.

This package provides functions designed to connect disease-related differential proteins and co-expression network. It provides the basic statics analysis included t test, ANOVA analysis. The network construction is not offered by the package, you can used WGCNA package which you can learn in Peter et al. (2008) <doi:10.1186/1471-2105-9-559>. It also provides module analysis included PCA analysis, two enrichment analysis, Planner maximally filtered graph extraction and hub analysis.

An efficient and convenient set of functions to perform differential network estimation through the use of alternating direction method of multipliers optimization with a variety of loss functions.

An implementation of common statistical analysis and models with differential privacy (Dwork et al., 2006a) <doi:10.1007/11681878_14> guarantees. The package contains, for example, functions providing differentially private computations of mean, variance, median, histograms, and contingency tables. It also implements some statistical models and machine learning algorithms such as linear regression (Kifer et al., 2012) <https://proceedings.mlr.press/v23/kifer12.html> and SVM (Chaudhuri et al., 2011) <https://jmlr.org/papers/v12/chaudhuri11a.html>. In addition, it implements some popular randomization mechanisms, including the Laplace mechanism (Dwork et al., 2006a) <doi:10.1007/11681878_14>, Gaussian mechanism (Dwork et al., 2006b) <doi:10.1007/11761679_29>, analytic Gaussian mechanism (Balle & Wang, 2018) <https://proceedings.mlr.press/v80/balle18a.html>, and exponential mechanism (McSherry & Talwar, 2007) <doi:10.1109/FOCS.2007.66>.

This package provides a suite of tools are provided here to support authors in making their research more discoverable. check_keywords() - this function checks the keywords to assess whether they are already represented in the title and abstract. check_fields() - this function compares terminology used across the title, abstract and keywords to assess where terminological diversity (i.e. the use of synonyms) could increase the likelihood of the record being identified in a search. The function looks for terms in the title and abstract that also exist in other fields and highlights these as needing attention. suggest_keywords() - this function takes a full text document and produces a list of unigrams, bigrams and trigrams (1-, 2- or 2-word phrases) present in the full text after removing stop words (words with a low utility in natural language processing) that do not occur in the title or abstract that may be suitable candidates for keywords. suggest_title() - this function takes a full text document and produces a list of the most frequently used unigrams, bigrams and trigrams after removing stop words that do not occur in the abstract or keywords that may be suitable candidates for title words. check_title() - this function carries out a number of sub tasks: 1) it compares the length (number of words) of the title with the mean length of titles in major bibliographic databases to assess whether the title is likely to be too short; 2) it assesses the proportion of stop words in the title to highlight titles with low utility in search engines that strip out stop words; 3) it compares the title with a given sample of record titles from an .ris import and calculates a similarity score based on phrase overlap. This highlights the level of uniqueness of the title. This version of the package also contains functions currently in a non-CRAN package called litsearchr <https://github.com/elizagrames/litsearchr>.

Discrete splines are a class of univariate piecewise polynomial functions which are analogous to splines, but whose smoothness is defined via divided differences rather than derivatives. Tools for efficient computations relating to discrete splines are provided here. These tools include discrete differentiation and integration, various matrix computations with discrete derivative or discrete spline bases matrices, and interpolation within discrete spline spaces. These techniques are described in Tibshirani (2020) <doi:10.48550/arXiv.2003.03886>.

This package provides the dose transition pathways (DTP) to project in advance the doses recommended by a model-based design for subsequent patients (stay, escalate, deescalate or stop early) using all the accumulated toxicity information; See Yap et al (2017) <doi: 10.1158/1078-0432.CCR-17-0582>. DTP can be used as a design and an operational tool and can be displayed as a table or flow diagram. The dtpcrm package also provides the modified continual reassessment method (CRM) and time-to-event CRM (TITE-CRM) with added practical considerations to allow stopping early when there is sufficient evidence that the lowest dose is too toxic and/or there is a sufficient number of patients dosed at the maximum tolerated dose.

Developed to Solve the Multi-Criteria Decision Making Problems with Decision Making Trial and Evaluation Laboratory Technique in R.