This package implements an efficient algorithm for solving sparse-penalized support vector machines with kernel density convolution. This package is designed for high-dimensional classification tasks, supporting lasso (L1) and elastic-net penalties for sparse feature selection and providing options for tuning kernel bandwidth and penalty weights. The dcsvm is applicable to fields such as bioinformatics, image analysis, and text classification, where high-dimensional data commonly arise. Learn more about the methodology and algorithm at Wang, Zhou, Gu, and Zou (2023) <doi:10.1109/TIT.2022.3222767>.

Interactively train neural networks on Numerai, <https://numer.ai/>, data. Generate tournament predictions and write them to a CSV.

This package provides a set of functions to quantify the relationship between development rate and temperature and to build phenological models. The package comprises a set of models and estimated parameters borrowed from a literature review in ectotherms. The methods and literature review are described in Rebaudo et al. (2018) <doi:10.1111/2041-210X.12935>, Rebaudo and Rabhi (2018) <doi:10.1111/eea.12693>, and Regnier et al. (2021) <doi:10.1093/ee/nvab115>. An example can be found in Rebaudo et al. (2017) <doi:10.1007/s13355-017-0480-5>.

Computations of Fisher's z-tests concerning different kinds of correlation differences. The diffpwr family entails approaches to estimating statistical power via Monte Carlo simulations. Important to note, the Pearson correlation coefficient is sensitive to linear association, but also to a host of statistical issues such as univariate and bivariate outliers, range restrictions, and heteroscedasticity (e.g., Duncan & Layard, 1973 <doi:10.1093/BIOMET/60.3.551>; Wilcox, 2013 <doi:10.1016/C2010-0-67044-1>). Thus, every power analysis requires that specific statistical prerequisites are fulfilled and can be invalid if the prerequisites do not hold. To this end, the bootcor family provides bootstrapping confidence intervals for the incorporated correlation difference tests.

This package performs sensitivity analysis for the sharp null, attributable effects, and weak nulls in matched studies with continuous exposures and binary or continuous outcomes as described in Zhang, Small, Heng (2024) <doi:10.48550/arXiv.2401.06909> and Zhang, Heng (2024) <doi:10.48550/arXiv.2409.12848>. Two of the functions require installation of the Gurobi optimizer. Please see <https://docs.gurobi.com/current/#refman/ins_the_r_package.html> for guidance.

The dataset package helps create semantically rich, machine-readable, and interoperable datasets in R. It extends tidy data frames with metadata that preserves meaning, improves interoperability, and makes datasets easier to publish, exchange, and reuse in line with ISO and W3C standards.

This package provides a facility to generate efficient designs for order-of-additions experiments under pair-wise-order model, see Dennis K. J. Lin and Jiayu Peng (2019)."Order-of-addition experiments: A review and some new thoughts". Quality Engineering, 31:1, 49-59, <doi:10.1080/08982112.2018.1548021>. It also provides a facility to generate component orthogonal arrays under component position model, see Jian-Feng Yang, Fasheng Sun & Hongquan Xu (2020): "A Component Position Model, Analysis and Design for Order-of-Addition Experiments". Technometrics, <doi:10.1080/00401706.2020.1764394>.

Fit logistic functions to observed dose-response continuous data and evaluate goodness-of-fit measures. See Malyutina A., Tang J., and Pessia A. (2023) <doi:10.18637/jss.v106.i04>.

Perform nonparametric Bayesian analysis using Dirichlet processes without the need to program the inference algorithms. Utilise included pre-built models or specify custom models and allow the dirichletprocess package to handle the Markov chain Monte Carlo sampling. Our Dirichlet process objects can act as building blocks for a variety of statistical models including and not limited to: density estimation, clustering and prior distributions in hierarchical models. See Teh, Y. W. (2011) <https://www.stats.ox.ac.uk/~teh/research/npbayes/Teh2010a.pdf>, among many other sources.

Create and manage fault-tolerant task queues for the foreach package using the Redis key/value database.

Analyzes group patterns using discourse analysis data with graph theory mathematics. Takes the order of which individuals talk and converts it to a network edge and weight list. Returns the density, centrality, centralization, and subgroup information for each group. Based on the analytical framework laid out in Chai et al. (2019) <doi:10.1187/cbe.18-11-0222>.

Fast functions for effective sample size, weighted multivariate mean, variance, and quantile computation, and weight diagnostic plot for generic importance sampling type or other probability weighted samples.

Generate reports that enable quick visual review of temporal shifts in record-level data. Time series plots showing aggregated values are automatically created for each data field (column) depending on its contents (e.g. min/max/mean values for numeric data, no. of distinct values for categorical data), as well as overviews for missing values, non-conformant values, and duplicated rows. The resulting reports are shareable and can contribute to forming a transparent record of the entire analysis process. It is designed with Electronic Health Records in mind, but can be used for any type of record-level temporal data (i.e. tabular data where each row represents a single "event", one column contains the "event date", and other columns contain any associated values for the event).

Basic routines used in scientific coding, such as timing routines, vector/array handing functions and I/O support routines.

This package provides a systematic biology tool was developed to repurpose drugs via a subpathway crosstalk network. The operation modes include 1) calculating centrality scores of SPs in the context of gene expression data to reflect the influence of SP crosstalk, 2) evaluating drug-disease reverse association based on disease- and drug-induced SPs weighted by the SP crosstalk, 3) identifying cancer candidate drugs through perturbation analysis. There are also several functions used to visualize the results.

This package provides functionality that assists in tabular description and statistical comparison of data.

An implementation of distributional random forests as introduced in Cevid & Michel & Meinshausen & Buhlmann (2020) <doi:10.48550/arXiv.2005.14458>.

Given a set of predictive quantiles from a distribution, estimate the distribution and create `d`, `p`, `q`, and `r` functions to evaluate its density function, distribution function, and quantile function, and generate random samples. On the interior of the provided quantiles, an interpolation method such as a monotonic cubic spline is used; the tails are approximated by a location-scale family.

In tumor tissue, underlying genomic instability can lead to DNA copy number alterations, e.g., copy number gains or losses. Sporadic copy number alterations occur randomly throughout the genome, whereas recurrent alterations are observed in the same genomic region across multiple independent samples, perhaps because they provide a selective growth advantage. Here we use cyclic shift permutations to identify recurrent copy number alterations in a single cohort or recurrent copy number differences in two cohorts based on a common set of genomic markers. Additional functionality is provided to perform downstream analyses, including the creation of summary files and graphics. DiNAMIC.Duo builds upon the original DiNAMIC package of Walter et al. (2011) <doi:10.1093/bioinformatics/btq717> and leverages the theory developed in Walter et al. (2015) <doi:10.1093/biomet/asv046>. An article describing DiNAMIC.Duo by Walter et al. (2022) can be found at <doi: 10.1093/bioinformatics/btac542>.

This package contains a range of functions covering the present development of the distributional method for the dichotomisation of continuous outcomes. The method provides estimates with standard error of a comparison of proportions (difference, odds ratio and risk ratio) derived, with similar precision, from a comparison of means. See the URL below or <arXiv:1809.03279> for more information.

This package provides a d-statistic tests the null hypothesis of no treatment effect in a matched, nonrandomized study of the effects caused by treatments. A d-statistic focuses on subsets of matched pairs that demonstrate insensitivity to unmeasured bias in such an observational study, correcting for double-use of the data by conditional inference. This conditional inference can, in favorable circumstances, substantially increase the power of a sensitivity analysis (Rosenbaum (2010) <doi:10.1007/978-1-4419-1213-8_14>). There are two examples, one concerning unemployment from Lalive et al. (2006) <doi:10.1111/j.1467-937X.2006.00406.x>, the other concerning smoking and periodontal disease from Rosenbaum (2017) <doi:10.1214/17-STS621>.

An easy-to-use yet powerful system for plotting grouped data effect sizes. Various types of effect size can be estimated, then plotted together with a representation of the original data. Select from many possible data representations (box plots, violin plots, raw data points etc.), and combine as desired. Durga plots are implemented in base R, so are compatible with base R methods for combining plots, such as layout()'. See Khan & McLean (2023) <doi:10.1101/2023.02.06.526960>.

Statistical tests and test statistics to identify events in a dataset that are dragon kings (DKs). The statistical methods in this package were reviewed in Wheatley & Sornette (2015) <doi:10.2139/ssrn.2645709>.

This package performs analysis of popular experimental designs used in the field of biological research. The designs covered are completely randomized design, randomized complete block design, factorial completely randomized design, factorial randomized complete block design, split plot design, strip plot design and latin square design. The analysis include analysis of variance, coefficient of determination, normality test of residuals, standard error of mean, standard error of difference and multiple comparison test of means. The package has functions for transformation of data and yield data conversion. Some datasets are also added in order to facilitate examples.