This package provides a random-effects stochastic model that allows quick detection of clonal dominance events from clonal tracking data collected in gene therapy studies. Starting from the Ito-type equation describing the dynamics of cells duplication, death and differentiation at clonal level, we first considered its local linear approximation as the base model. The parameters of the base model, which are inferred using a maximum likelihood approach, are assumed to be shared across the clones. Although this assumption makes inference easier, in some cases it can be too restrictive and does not take into account possible scenarios of clonal dominance. Therefore we extended the base model by introducing random effects for the clones. In this extended formulation the dynamic parameters are estimated using a tailor-made expectation maximization algorithm. Further details on the methods can be found in L. Del Core et al., (2022) <doi:10.1101/2022.05.31.494100>.

Helps to fit thermal performance curves (TPCs). rTPC contains 26 model formulations previously used to fit TPCs and has helper functions to set sensible start parameters, upper and lower parameter limits and estimate parameters useful in downstream analyses, such as cardinal temperatures, maximum rate and optimum temperature. See Padfield et al. (2021) <doi:10.1111/2041-210X.13585>.

This package provides robust methods to detect change-points in uni- or multivariate time series. They can cope with corrupted data and heavy tails. Focus is on the detection of abrupt changes in location, but changes in the scale or dependence structure can be detected as well. This package provides tests for change detection in uni- and multivariate time series based on Huberized versions of CUSUM tests proposed in Duerre and Fried (2019) <DOI:10.48550/arXiv.1905.06201>, and tests for change detection in univariate time series based on 2-sample U-statistics or 2-sample U-quantiles as proposed by Dehling et al. (2015) <DOI:10.1007/978-1-4939-3076-0_12> and Dehling, Fried and Wendler (2020) <DOI:10.1093/biomet/asaa004>. Furthermore, the packages provides tests on changes in the scale or the correlation as proposed in Gerstenberger, Vogel and Wendler (2020) <DOI:10.1080/01621459.2019.1629938>, Dehling et al. (2017) <DOI:10.1017/S026646661600044X>, and Wied et al. (2014) <DOI:10.1016/j.csda.2013.03.005>.

Interoperability between Rcpp and the C++11 array and tuple types. Linking to this package allows fixed-length std::array objects to be converted to and from equivalent R vectors, and std::tuple objects converted to lists, via the as() and wrap() functions. There is also experimental support for std::span from C++20'.

Minirhizotrons are widely used to observe and explore roots and their growth. This package provides the means to stitch images and divide them into depth layers. Please note that this R package was developed alongside the following manuscript: Stitching root scans and extracting depth layer information -- a workflow and practical examples, S. Kersting, L. Knüver, and M. Fischer. The manuscript is currently in preparation and should be citet as soon as it is available. This project was supported by the project ArtIGROW, which is a part of the WIR!-Alliance ArtIFARM â Artificial Intelligence in Farming funded by the German Federal Ministry of Research, Technology and Space (No. 03WIR4805).

An R Commander plug-in for the WorldFlora package. It was mainly developed to show work flows and scripts for first-time users.

Package runonce helps automating the saving of long-running code to help running the same code multiple times. If you run some long-running code once, it saves the result in a file on disk. Then, if the result already exists, i.e. if the code has already been run and its output has already been saved, it just reads the result from the stored file instead of running the code again.

We implement linear regression when the outcome of interest and some of the covariates are observed in two different datasets that cannot be linked, based on D'Haultfoeuille, Gaillac, Maurel (2022) <doi:10.3386/w29953>. The package allows for common regressors observed in both datasets, and for various shape constraints on the effect of covariates on the outcome of interest. It also provides the tools to perform a test of point identification. See the associated vignette <https://github.com/cgaillac/RegCombin/blob/master/RegCombin_vignette.pdf> for theory and code examples.

Fundamental formulas for Radar, for attenuation, range, velocity, effectiveness, power, scatter, doppler, geometry, radar equations, etc. Based on Nick Guy's Python package PyRadarMet.

Base S4-classes and functions for robust asymptotic statistics.

This package provides functions and datasets required for the ST 370 course at North Carolina State University.

Streamlines the creation of reproducible analytical pipelines using default.nix expressions generated via the rix package for reproducibility. Define derivations in R', Python or Julia', chain them into a composition of pure functions and build the resulting pipeline using Nix as the underlying end-to-end build tool. Functions to plot the pipeline as a directed acyclic graph are included, as well as functions to load and inspect intermediary results for interactive analysis. User experience heavily inspired by the targets package.

This package provides access to global river gauge data from a variety of national-level river agencies. The package interfaces with the national-level agency websites to provide access to river gauge locations, river discharge, and river stage. Currently, the package is available for the following countries: Australia, Brazil, Canada, Chile, France, Japan, South Africa, the United Kingdom, and the United States.

Non-linear transformations of data to better discover latent effects. Applies a sequence of three transformations (1) a Gaussianizing transformation, (2) a Z-score transformation, and (3) an outlier removal transformation. A publication describing the method has the following citation: Gregory J. Hunt, Mark A. Dane, James E. Korkola, Laura M. Heiser & Johann A. Gagnon-Bartsch (2020) "Automatic Transformation and Integration to Improve Visualization and Discovery of Latent Effects in Imaging Data", Journal of Computational and Graphical Statistics, <doi:10.1080/10618600.2020.1741379>.

BaseX <https://basex.org> is a XML database engine and a compliant XQuery 3.1 processor with full support of W3C Update Facility'. This package is a full client-implementation of the client/server protocol for BaseX and provides functionalities to create, manipulate and query on XML-data.

The TRUST4 or MiXCR is used to identify the clonotypes. The goal of rTCRBCRr is to process the results from these clonotyping tools, and analyze the clonotype repertoire metrics based on chain names and IGH isotypes. The manuscript is still under preparation for publication for now. The references describing the methods in this package will be added later.

An implementation of simulated maximum likelihood method for the estimation of Binary (Probit and Logit), Ordered (Probit and Logit) and Poisson models with random parameters for cross-sectional and longitudinal data as presented in Sarrias (2016) <doi:10.18637/jss.v074.i10>.

This package contains functions to generate random numbers from the beta distribution and random vectors from the Dirichlet distribution.

Multiscale Curvature Classification of ground returns in 3-D LiDAR point clouds, designed for forested environments. RMCC is a porting to R of the MCC-lidar method by Evans and Hudak (2007) <doi:10.1109/TGRS.2006.890412>.

Implementations of several robust nonparametric two-sample tests for location or scale differences. The test statistics are based on robust location and scale estimators, e.g. the sample median or the Hodges-Lehmann estimators as described in Fried & Dehling (2011) <doi:10.1007/s10260-011-0164-1>. The p-values can be computed via the permutation principle, the randomization principle, or by using the asymptotic distributions of the test statistics under the null hypothesis, which ensures (approximate) distribution independence of the test decision. To test for a difference in scale, we apply the tests for location difference to transformed observations; see Fried (2012) <doi:10.1016/j.csda.2011.02.012>. Random noise on a small range can be added to the original observations in order to hold the significance level on data from discrete distributions. The location tests assume homoscedasticity and the scale tests require the location parameters to be zero.

This package provides a trimmed down copy of the "kent-core source tree" turned into a C library for manipulation of .2bit files. See <https://genome.ucsc.edu/FAQ/FAQformat.html#format7> for a quick overview of the 2bit format. The "kent-core source tree" can be found here: <https://github.com/ucscGenomeBrowser/kent-core/>. Only the .c and .h files from the source tree that are related to manipulation of .2bit files were kept. Note that the package is primarily useful to developers of other R packages who wish to use the 2bit C library in their own C'/'C++ code.

This package provides color schemes for maps and other graphics designed by CARTO as described at <https://carto.com/carto-colors/>. It includes four types of palettes: aggregation, diverging, qualitative, and quantitative.

Rectangle packing is a packing problem where rectangles are placed into a larger rectangular region (without overlapping) in order to maximise the use space. Rectangles are packed using the skyline heuristic as discussed in Lijun et al (2011) A Skyline-Based Heuristic for the 2D Rectangular Strip Packing Problem <doi:10.1007/978-3-642-21827-9_29>. A function is also included for determining a good small-sized box for containing a given set of rectangles.

This package provides the user with functions to develop their trading strategy, uncover actionable trading ideas, and monitor consensus shifts with crowdsourced earnings and economic estimate data directly from <www.estimize.com>. Further information regarding the web services this package invokes can be found at <www.estimize.com/api>.