The concept of Essential Biodiversity Variables (EBV, <https://geobon.org/ebvs/what-are-ebvs/>) comes with a data structure based on the Network Common Data Form (netCDF). The ebvcube R package provides functionality to easily create, access and visualise this data. The EBV netCDFs can be downloaded from the EBV Data Portal: Christian Langer/ iDiv (2020) <https://portal.geobon.org/>.

This package creates graphs of species associations (interactions) and ordination biplots from co-occurrence data by fitting discrete gaussian copula graphical models. Methods described in Popovic, GC., Hui, FKC., Warton, DI., (2018) <doi:10.1016/j.jmva.2017.12.002>.

This package performs the exact test on whether there is a difference between two survival curves. Exact confidence interval for the hazard ratio can also be generated for the Cox model.

Bindings to edlib, a lightweight performant C/C++ library for exact pairwise sequence alignment using edit distance (Levenshtein distance). The algorithm computes the optimal alignment path, but also can be used to find only the start and/or end of the alignment path for convenience. Edlib was designed to be ultrafast and require little memory, with the capability to handle very large sequences. Three alignment methods are supported: global (Needleman-Wunsch), infix (Hybrid Wunsch), and prefix (Semi-Hybrid Wunsch). The original C/C++ library is described in "Edlib: a C/C++ library for fast, exact sequence alignment using edit distance", M. Å oÅ¡iÄ , M. Å ikiÄ , <doi:10.1093/bioinformatics/btw753>.

This includes a dataset on the outcomes of the USA presidential elections since 1920, and various predictors, as used in <https://www.vanderwalresearch.com/blog/15-elections>.

This package provides methods for working with dose-finding clinical trials. We provide implementations of many dose-finding clinical trial designs, including the continual reassessment method (CRM) by O'Quigley et al. (1990) <doi:10.2307/2531628>, the toxicity probability interval (TPI) design by Ji et al. (2007) <doi:10.1177/1740774507079442>, the modified TPI (mTPI) design by Ji et al. (2010) <doi:10.1177/1740774510382799>, the Bayesian optimal interval design (BOIN) by Liu & Yuan (2015) <doi:10.1111/rssc.12089>, EffTox by Thall & Cook (2004) <doi:10.1111/j.0006-341X.2004.00218.x>; the design of Wages & Tait (2015) <doi:10.1080/10543406.2014.920873>, and the 3+3 described by Korn et al. (1994) <doi:10.1002/sim.4780131802>. All designs are implemented with a common interface. We also offer optional additional classes to tailor the behaviour of all designs, including avoiding skipping doses, stopping after n patients have been treated at the recommended dose, stopping when a toxicity condition is met, or demanding that n patients are treated before stopping is allowed. By daisy-chaining together these classes using the pipe operator from magrittr', it is simple to tailor the behaviour of a dose-finding design so it behaves how the trialist wants. Having provided a flexible interface for specifying designs, we then provide functions to run simulations and calculate dose-paths for future cohorts of patients.

Testing for parallel trends is crucial in the Difference-in-Differences framework. To this end, this package performs equivalence testing in the context of Difference-in-Differences estimation. It allows users to test if pre-treatment trends in the treated group are â equivalentâ to those in the control group. Here, â equivalenceâ means that rejection of the null hypothesis implies that a function of the pre-treatment placebo effects (maximum absolute, average or root mean squared value) does not exceed a pre-specified threshold below which trend differences are considered negligible. The package is based on the theory developed in Dette & Schumann (2024) <doi:10.1080/07350015.2024.2308121>.

Empirical Bayes ranking applicable to parallel-estimation settings where the estimated parameters are asymptotically unbiased and normal, with known standard errors. A mixture normal prior for each parameter is estimated using Empirical Bayes methods, subsequentially ranks for each parameter are simulated from the resulting joint posterior over all parameters (The marginal posterior densities for each parameter are assumed independent). Finally, experiments are ordered by expected posterior rank, although computations minimizing other plausible rank-loss functions are also given.

This package provides a function for distribution free control chart based on the change point model, for multivariate statistical process control. The main constituent of the chart is the energy test that focuses on the discrepancy between empirical characteristic functions of two random vectors. This new control chart highlights in three aspects. Firstly, it is distribution free, requiring no knowledge of the random processes. Secondly, this control chart can monitor mean and variance simultaneously. Thirdly it is devised for multivariate time series which is more practical in real data application. Fourthly, it is designed for online detection (Phase II), which is central for real time surveillance of stream data. For more information please refer to O. Okhrin and Y.F. Xu (2017) <https://github.com/YafeiXu/working_paper/raw/master/CPM102.pdf>.

This package provides various statistical methods for evaluating Individualized Treatment Rules under randomized data. The provided metrics include Population Average Value (PAV), Population Average Prescription Effect (PAPE), Area Under Prescription Effect Curve (AUPEC). It also provides the tools to analyze Individualized Treatment Rules under budget constraints. Detailed reference in Imai and Li (2019) <arXiv:1905.05389>.

Fast and memory-less computation of the energy statistics related quantities for vectors and matrices. References include: Szekely G. J. and Rizzo M. L. (2014), <doi:10.1214/14-AOS1255>. Szekely G. J. and Rizzo M. L. (2023), <ISBN:9781482242744>. Tsagris M. and Papadakis M. (2025). <doi:10.48550/arXiv.2501.02849>.

Estimates RxC (R by C) vote transfer matrices (ecological contingency tables) from aggregate data building on Thomsen (1987) and Park (2008) approaches. References: Park, W.-H. (2008). Ecological Inference and Aggregate Analysis of Election''. PhD Dissertation. University of Michigan. <https://deepblue.lib.umich.edu/bitstream/handle/2027.42/58525/wpark_1.pdf> Thomsen, S.R. (1987, ISBN:87-7335-037-2). Danish Elections 1920 79: a Logit Approach to Ecological Analysis and Inference''. Politica, Aarhus, Denmark.

Utilities for building certain kinds of common matrices and models in the extended structural equation modeling package, OpenMx'.

This package provides functions to create simulated time series of environmental exposures (e.g., temperature, air pollution) and health outcomes for use in power analysis and simulation studies in environmental epidemiology. This package also provides functions to evaluate the results of simulation studies based on these simulated time series. This work was supported by a grant from the National Institute of Environmental Health Sciences (R00ES022631) and a fellowship from the Colorado State University Programs for Research and Scholarly Excellence.

This package provides environment hooks that obtain errors and warnings which occur during the execution of code to automatically search for solutions.

Bayesian Model Averaging to create probabilistic forecasts from ensemble forecasts and weather observations <https://stat.uw.edu/sites/default/files/files/reports/2007/tr516.pdf>.

Calculates several indices, such as of diversity, fluctuation, etc., and they are used to estimate ecological indicators.

Evidential regression analysis for dichotomous and quantitative outcome data. The following references described the methods in this package: Strug, L. J., Hodge, S. E., Chiang, T., Pal, D. K., Corey, P. N., & Rohde, C. (2010) <doi:10.1038/ejhg.2010.47>. Strug, L. J., & Hodge, S. E. (2006) <doi:10.1159/000094709>. Royall, R. (1997) <ISBN:0-412-04411-0>.

This package provides a small collection of datasets supporting Pearson correlation and linear regression analysis. It includes the precomputed dataset sos100', with integer values summing to zero and squared sum equal to 100. For other values of n and user-defined parameters, the sos() function from the exams.forge package can be used to generate datasets on the fly. In addition, the package contains around 500 german R Markdown exercises that illustrate the usage of exams.forge commands.

This package implements stochastic simulations of community assembly (ecological diversification) using customizable ecospace frameworks (functional trait spaces). Provides a wrapper to calculate common ecological disparity and functional ecology statistical dynamics as a function of species richness. Functions are written so they will work in a parallel-computing environment.

This package provides functions to align curves and to compute mean curves based on the elastic distance defined in the square-root-velocity framework. For more details on this framework see Srivastava and Klassen (2016, <doi:10.1007/978-1-4939-4020-2>). For more theoretical details on our methods and algorithms see Steyer et al. (2023, <doi:10.1111/biom.13706>) and Steyer et al. (2023, <arXiv:2305.02075>).

Allows access to data in running instance of Microsoft Excel (e. g. xl[a1] = xl[b2]*3 and so on). Graphics can be transferred with xl[a1] = current.graphics()'. Additionally there are function for reading/writing Excel files - xl.read.file'/'xl.save.file'. They are not fast but able to read/write *.xlsb'-files and password-protected files. There is an Excel workbook with examples of calling R from Excel in the doc folder. It tries to keep things as simple as possible - there are no needs in any additional installations besides R, only VBA code in the Excel workbook. Microsoft Excel is required for this package.

Pupillometry offers a non-invasive window into the mind and has been used extensively as a psychophysiological readout of arousal signals linked with cognitive processes like attention, stress, and emotional states [Clewett et al. (2020) <doi:10.1038/s41467-020-17851-9>; Kret & Sjak-Shie (2018) <doi:10.3758/s13428-018-1075-y>; Strauch (2024) <doi:10.1016/j.tins.2024.06.002>]. Yet, despite decades of pupillometry research, many established packages and workflows to date lack design patterns based on Findability, Accessibility, Interoperability, and Reusability (FAIR) principles [see Wilkinson et al. (2016) <doi:10.1038/sdata.2016.18>]. eyeris provides a modular, performant, and extensible preprocessing framework for pupillometry data with BIDS-like organization and interactive output reports [Esteban et al. (2019) <doi:10.1038/s41592-018-0235-4>; Gorgolewski et al. (2016) <doi:10.1038/sdata.2016.44>]. Development was supported, in part, by the Stanford Wu Tsai Human Performance Alliance, Stanford Ric Weiland Graduate Fellowship, Stanford Center for Mind, Brain, Computation and Technology, NIH National Institute on Aging Grants (R01-AG065255, R01-AG079345), NSF GRFP (DGE-2146755), McKnight Brain Research Foundation Clinical Translational Research Scholarship in Cognitive Aging and Age-Related Memory Loss, American Brain Foundation, and the American Academy of Neurology.

An eikosogram (ancient Greek for probability picture) divides the unit square into rectangular regions whose areas, sides, and widths represent various probabilities associated with the values of one or more categorical variates. Rectangle areas are joint probabilities, widths are always marginal (though possibly joint margins, i.e. marginal joint distributions of two or more variates), and heights of rectangles are always conditional probabilities. Eikosograms embed the rules of probability and are useful for introducing elementary probability theory, including axioms, marginal, conditional, and joint probabilities, and their relationships (including Bayes theorem as a completely trivial consequence). They provide advantages over Venn diagrams for this purpose, particularly in distinguishing probabilistic independence, mutually exclusive events, coincident events, and associations. They also are useful for identifying and understanding conditional independence structure. Eikosograms can be thought of as mosaic plots when only two categorical variates are involved; the layout is quite different when there are more than two variates. Only one categorical variate, designated the "response", presents on the vertical axis and all others, designated the "conditioning" variates, appear on the horizontal. In this way, conditional probability appears only as height and marginal probabilities as widths. The eikosogram is ideal for response models (e.g. logistic models) but equally useful when no variate is distinguished as the response. In such cases, each variate can appear in turn as the response, which is handy for assessing conditional independence in discrete graphical models (i.e. "Bayesian networks" or "BayesNets"). The eikosogram and its value over Venn diagrams in teaching probability is described in W.H. Cherry and R.W. Oldford (2003) <https://math.uwaterloo.ca/~rwoldfor/papers/eikosograms/paper.pdf>, its value in exploring conditional independence structure and relation to graphical and log-linear models is described in R.W. Oldford (2003) <https://math.uwaterloo.ca/~rwoldfor/papers/eikosograms/independence/paper.pdf>, and a number of problems, puzzles, and paradoxes that are easily explained with eikosograms are given in R.W. Oldford (2003) <https://math.uwaterloo.ca/~rwoldfor/papers/eikosograms/examples/paper.pdf>.