Caches and then connects to a sqlite database containing half a million pediatric drug safety signals. The database is part of a family of resources catalogued at <https://nsides.io>. The database contains 17 tables where the description table provides a map between the fields the field's details. The database was created by Nicholas Giangreco during his PhD thesis which you can read in Giangreco (2022) <doi:10.7916/d8-5d9b-6738>. The observations are from the Food and Drug Administration's Adverse Event Reporting System. Generalized additive models estimated drug effects across child development stages for the occurrence of an adverse event when exposed to a drug compared to other drugs. Read more at the methods detailed in Giangreco (2022) <doi:10.1016/j.medj.2022.06.001>.

Understanding the current status of forest resources is essential for monitoring changes in forest ecosystems and generating related statistics. In South Korea, the National Forest Inventory (NFI) surveys over 4,500 sample plots nationwide every five years and records 70 items, including forest stand, forest resource, and forest vegetation surveys. Many researchers use NFI as the primary data for research, such as biomass estimation or analyzing the importance value of each species over time and space, depending on the research purpose. However, the large volume of accumulated forest survey data from across the country can make it challenging to manage and utilize such a vast dataset. To address this issue, we developed an R package that efficiently handles large-scale NFI data across time and space. The package offers a comprehensive workflow for NFI data analysis. It starts with data processing, where read_nfi() function reconstructs NFI data according to the researcher's needs while performing basic integrity checks for data quality.Following this, the package provides analytical tools that operate on the verified data. These include functions like summary_nfi() for summary statistics, diversity_nfi() for biodiversity analysis, iv_nfi() for calculating species importance value, and biomass_nfi() and cwd_biomass_nfi() for biomass estimation. Finally, for visualization, the tsvis_nfi() function generates graphs and maps, allowing users to visualize forest ecosystem changes across various spatial and temporal scales. This integrated approach and its specialized functions can enhance the efficiency of processing and analyzing NFI data, providing researchers with insights into forest ecosystems. The NFI Excel files (.xlsx) are not included in the R package and must be downloaded separately. Users can access these NFI Excel files by visiting the Korea Forest Service Forestry Statistics Platform <https://kfss.forest.go.kr/stat/ptl/article/articleList.do?curMenu=11694&bbsId=microdataboard> to download the annual NFI Excel files, which are bundled in .zip archives. Please note that this website is only available in Korean, and direct download links can be found in the notes section of the read_nfi() function.

Implementations of two empirical versions the kernel partial correlation (KPC) coefficient and the associated variable selection algorithms. KPC is a measure of the strength of conditional association between Y and Z given X, with X, Y, Z being random variables taking values in general topological spaces. As the name suggests, KPC is defined in terms of kernels on reproducing kernel Hilbert spaces (RKHSs). The population KPC is a deterministic number between 0 and 1; it is 0 if and only if Y is conditionally independent of Z given X, and it is 1 if and only if Y is a measurable function of Z and X. One empirical KPC estimator is based on geometric graphs, such as K-nearest neighbor graphs and minimum spanning trees, and is consistent under very weak conditions. The other empirical estimator, defined using conditional mean embeddings (CMEs) as used in the RKHS literature, is also consistent under suitable conditions. Using KPC, a stepwise forward variable selection algorithm KFOCI (using the graph based estimator of KPC) is provided, as well as a similar stepwise forward selection algorithm based on the RKHS based estimator. For more details on KPC, its empirical estimators and its application on variable selection, see Huang, Z., N. Deb, and B. Sen (2022). â Kernel partial correlation coefficient â a measure of conditional dependenceâ (URL listed below). When X is empty, KPC measures the unconditional dependence between Y and Z, which has been described in Deb, N., P. Ghosal, and B. Sen (2020), â Measuring association on topological spaces using kernels and geometric graphsâ <arXiv:2010.01768>, and it is implemented in the functions KMAc() and Klin() in this package. The latter can be computed in near linear time.

Selection of k in k-means clustering based on Pham et al. paper ``Selection of k in k-means clustering''.

This package provides a collection of personal helper functions to avoid redundancy in the spirit of the "Don't repeat yourself" principle of software development (<https://en.wikipedia.org/wiki/Don%27t_repeat_yourself>).

Optimized for handling complex datasets in environmental and ecological research, this package offers functionality that is not fully met by general-purpose packages. It provides two key functions, summarize_data()', which summarizes datasets, and plot_means()', which creates plots with error bars. The plot_means() function incorporates error bars by default, allowing quick visualization of uncertainties, crucial in ecological studies. It also streamlines workflows for grouped datasets (e.g., by species or treatment), making it particularly user-friendly and reducing the complexity and time required for data summarization and visualization.

Metadata about populations and data about samples from the 1000 Genomes Project, including the 2,504 samples sequenced for the Phase 3 release and the expanded collection of 3,202 samples with 602 additional trios. The data is described in Auton et al. (2015) <doi:10.1038/nature15393> and Byrska-Bishop et al. (2022) <doi:10.1016/j.cell.2022.08.004>, and raw data is available at <http://ftp.1000genomes.ebi.ac.uk/vol1/ftp/>. See Turner (2022) <doi:10.48550/arXiv.2210.00539> for more details.

Kernel smoothing for Wishart random matrices described in Daayeb, Khardani and Ouimet (2025) <doi:10.48550/arXiv.2506.08816>, Gaussian and log-Gaussian models using least square or likelihood cross validation criteria for optimal bandwidth selection.

Create a kite-square plot for contingency tables using ggplot2', to display their relevant quantities in a single figure (marginal, conditional, expected, observed, chi-squared). The plot resembles a flying kite inside a square if the variables are independent, and deviates from this the more dependence exists.

In self-reported or anonymised data the user often encounters heaped data, i.e. data which are rounded (to a possibly different degree of coarseness). While this is mostly a minor problem in parametric density estimation the bias can be very large for non-parametric methods such as kernel density estimation. This package implements a partly Bayesian algorithm treating the true unknown values as additional parameters and estimates the rounding parameters to give a corrected kernel density estimate. It supports various standard bandwidth selection methods. Varying rounding probabilities (depending on the true value) and asymmetric rounding is estimable as well: Gross, M. and Rendtel, U. (2016) (<doi:10.1093/jssam/smw011>). Additionally, bivariate non-parametric density estimation for rounded data, Gross, M. et al. (2016) (<doi:10.1111/rssa.12179>), as well as data aggregated on areas is supported.

Criteria and algorithms for sequentially estimating level sets of a multivariate numerical function, possibly observed with noise.

Distance metrics for mixed-type data consisting of continuous, nominal, and ordinal variables. This methodology uses additive and product kernels to calculate similarity functions and metrics, and selects variables relevant to the underlying distance through bandwidth selection via maximum similarity cross-validation. These methods can be used in any distance-based algorithm, such as distance-based clustering. For further details, we refer the reader to Ghashti and Thompson (2024) <doi:10.1007/s00357-024-09493-z> for dkps() methodology, and Ghashti (2024) <doi:10.14288/1.0443975> for dkss() methodology.

New kernel-based test and fast tests for testing whether two samples are from the same distribution. They work well particularly for high-dimensional data. Song, H. and Chen, H. (2023) <arXiv:2011.06127>.

This package provides a high-performance R interface to the kuzu graph database. It uses the reticulate package to wrap the official Python client ('kuzu', pandas', and networkx'), allowing users to interact with kuzu seamlessly from within R'. Key features include managing database connections, executing Cypher queries, and efficiently loading data from R data frames. It also provides seamless integration with the R ecosystem by converting query results directly into popular R data structures, including tibble', igraph', tidygraph', and g6R objects, making kuzu's powerful graph computation capabilities readily available for data analysis and visualization workflows in R'. The kuzu documentation can be found at <https://kuzudb.github.io/docs/>.

Rcpp implementation of the multivariate Kim filter, which combines the Kalman and Hamilton filters for state probability inference. The filter is designed for state space models and can handle missing values and exogenous data in the observation and state equations. Kim, Chang-Jin and Charles R. Nelson (1999) "State-Space Models with Regime Switching: Classical and Gibbs-Sampling Approaches with Applications" <doi:10.7551/mitpress/6444.001.0001><http://econ.korea.ac.kr/~cjkim/>.

This package implements several methods for testing the variance component parameter in regression models that contain kernel-based random effects, including a maximum of adjusted scores test. Several kernels are supported, including a profile hidden Markov model mutual information kernel for protein sequence. This package is described in Fong et al. (2015) <DOI:10.1093/biostatistics/kxu056>.

This package implements a quantified approach to the Kraljic Matrix (Kraljic, 1983, <https://hbr.org/1983/09/purchasing-must-become-supply-management>) for strategically analyzing a firmâ s purchasing portfolio. It combines multi-objective decision analysis to measure purchasing characteristics and uses this information to place products and services within the Kraljic Matrix.

This package infers relative kinase activity from phosphoproteomics data using the method described by Casado et al. (2013) <doi:10.1126/scisignal.2003573>.

Makes visually pleasing diagrams of knot projections using optimized Bezier curves.

Structural T1 magnetic resonance imaging ('MRI') data from the Kirby21 reproducibility study <doi:10.1016/j.neuroimage.2010.11.047>.

The goal of kronos is to provide an easy-to-use framework to analyse circadian or otherwise rhythmic data using the familiar R linear modelling syntax, while taking care of the trigonometry under the hood.

Assists researchers in choosing Key Opinion Leaders (KOLs) in a network to help disseminate or encourage adoption of an innovation by other network members. Potential KOL teams are evaluated using the ABCDE framework (Neal et al., 2025 <doi:10.31219/osf.io/3vxy9_v1>). This framework which considers: (1) the team members Availability, (2) the Breadth of the team's network coverage, (3) the Cost of recruiting a team of a given size, and (4) the Diversity of the team's members, (5) which are pooled into a single Evaluation score.

This package provides an easy way to create interactive KPI (key performance indicator) widgets for Quarto dashboards using Crosstalk'. The package enables visualization of key metrics in a structured format, supporting interactive filtering and linking with other Crosstalk'-enabled components. Designed for use in Quarto Dashboards.

The kernelized version of principal component analysis (KPCA) has proven to be a valid nonlinear alternative for tackling the nonlinearity of biological sample spaces. However, it poses new challenges in terms of the interpretability of the original variables. kpcaIG aims to provide a tool to select the most relevant variables based on the kernel PCA representation of the data as in Briscik et al. (2023) <doi:10.1186/s12859-023-05404-y>. It also includes functions for 2D and 3D visualization of the original variables (as arrows) into the kernel principal components axes, highlighting the contribution of the most important ones.