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Computation of linkage disequilibrium of ancestry (LDA) and linkage disequilibrium of ancestry score (LDAS). LDA calculates the pairwise linkage disequilibrium of ancestry between single nucleotide polymorphisms (SNPs). LDAS calculates the LDA score of SNPs. The methods are described in Barrie W, Yang Y, Irving-Pease E.K, et al (2024) <doi:10.1038/s41586-023-06618-z>.
Convenient aliases for common ways of misspelling the base R function length(). These include every permutation of the final three letters.
Rapid satellite data streams in operational applications have clear benefits for monitoring land cover, especially when information can be delivered as fast as changing surface conditions. Over the past decade, remote sensing has become a key tool for monitoring and predicting environmental variables by using satellite data. This package presents the main applications in remote sensing for land surface monitoring and land cover mapping (soil, vegetation, water...). Tomlinson, C.J., Chapman, L., Thornes, E., Baker, C (2011) <doi:10.1002/met.287>.
Implementation of several phenotype-based family genetic risk scores with unified input data and data preparation functions to help facilitate the required data preparation and management. The implemented family genetic risk scores are the extended liability threshold model conditional on family history from Pedersen (2022) <doi:10.1016/j.ajhg.2022.01.009> and Pedersen (2023) <https://www.nature.com/articles/s41467-023-41210-z>, Pearson-Aitken Family Genetic Risk Scores from Krebs (2024) <doi:10.1016/j.ajhg.2024.09.009>, and family genetic risk score from Kendler (2021) <doi:10.1001/jamapsychiatry.2021.0336>.
Allows researchers to conduct multivariate statistical analyses of survey data with list experiments. This survey methodology is also known as the item count technique or the unmatched count technique and is an alternative to the commonly used randomized response method. The package implements the methods developed by Imai (2011) <doi:10.1198/jasa.2011.ap10415>, Blair and Imai (2012) <doi:10.1093/pan/mpr048>, Blair, Imai, and Lyall (2013) <doi:10.1111/ajps.12086>, Imai, Park, and Greene (2014) <doi:10.1093/pan/mpu017>, Aronow, Coppock, Crawford, and Green (2015) <doi:10.1093/jssam/smu023>, Chou, Imai, and Rosenfeld (2017) <doi:10.1177/0049124117729711>, and Blair, Chou, and Imai (2018) <https://imai.fas.harvard.edu/research/files/listerror.pdf>. This includes a Bayesian MCMC implementation of regression for the standard and multiple sensitive item list experiment designs and a random effects setup, a Bayesian MCMC hierarchical regression model with up to three hierarchical groups, the combined list experiment and endorsement experiment regression model, a joint model of the list experiment that enables the analysis of the list experiment as a predictor in outcome regression models, a method for combining list experiments with direct questions, and methods for diagnosing and adjusting for response error. In addition, the package implements the statistical test that is designed to detect certain failures of list experiments, and a placebo test for the list experiment using data from direct questions.
Suite of R functions for the estimation of the local false discovery rate (LFDR) using Type II maximum likelihood estimation (MLE).
Several leaflet plugins are integrated, which are available as extension to the leaflet package.
Insieme di funzioni di supporto al volume "Laboratorio di Statistica con R", Iacus-Masarotto, MacGraw-Hill Italia, 2006. This package contains sets of functions defined in "Laboratorio di Statistica con R", Iacus-Masarotto, MacGraw-Hill Italia, 2006. Function names and docs are in italian as well.
Latent Markov models for longitudinal continuous and categorical data. See Bartolucci, Pandolfi, Pennoni (2017)<doi:10.18637/jss.v081.i04>.
The package converts R data onto input and data for LocalSolver, executes optimization and exposes optimization results as R data. LocalSolver (http://www.localsolver.com/) is an optimization engine developed by Innovation24 (http://www.innovation24.fr/). It is designed to solve large-scale mixed-variable non-convex optimization problems. The localsolver package is developed and maintained by WLOG Solutions (http://www.wlogsolutions.com/en/) in collaboration with Decision Support and Analysis Division at Warsaw School of Economics (http://www.sgh.waw.pl/en/).
Embarrassingly Parallel Linear Mixed Model calculations spread across local cores which repeat until convergence.
This package provides functions for forest objects detection, structure metrics computation, model calibration and mapping with airborne laser scanning: co-registration of field plots (Monnet and Mermin (2014) <doi:10.3390/f5092307>); tree detection (method 1 in Eysn et al. (2015) <doi:10.3390/f6051721>) and segmentation; forest parameters estimation with the area-based approach: model calibration with ground reference, and maps export (Aussenac et al. (2023) <doi:10.12688/openreseurope.15373.2>); extraction of both physical (gaps, edges, trees) and statistical features useful for e.g. habitat suitability modeling (Glad et al. (2020) <doi:10.1002/rse2.117>) and forest maturity mapping (Fuhr et al. (2022) <doi:10.1002/rse2.274>).
Shiny apps for the quantitative analysis of images from lateral flow assays (LFAs). The images are segmented and background corrected and color intensities are extracted. The apps can be used to import and export intensity data and to calibrate LFAs by means of linear, loess, or gam models. The calibration models can further be saved and applied to intensity data from new images for determining concentrations.
Fast binning of multiple variables using parallel processing. A summary of all the variables binned is generated which provides the information value, entropy, an indicator of whether the variable follows a monotonic trend or not, etc. It supports rebinning of variables to force a monotonic trend as well as manual binning based on pre specified cuts. The cut points of the bins are based on conditional inference trees as implemented in the partykit package. The conditional inference framework is described by Hothorn T, Hornik K, Zeileis A (2006) <doi:10.1198/106186006X133933>.
Perform pairwise likelihood inference in latent autoregressive count models. See Pedeli and Varin (2020) for details.
This package provides tools to decompose differences in cohort health expectancy (HE) by age and cause using longitudinal data. The package implements a novel longitudinal attribution method based on a semiparametric additive hazards model with time-dependent covariates, specifically designed to address interval censoring and semi-competing risks via a copula framework. The resulting age-cause-specific contributions to disability prevalence and death probability can be used to quantify and decompose differences in cohort HE between groups. The package supports stepwise replacement decomposition algorithms and is applicable to cohort-based health disparity research across diverse populations. Related methods include Sun et al. (2023) <doi:10.1177/09622802221133552>.
Labels are a common construct in statistical software providing a human readable description of a variable. While variable names are succinct, quick to type, and follow a language's naming conventions, labels may be more illustrative and may use plain text and spaces. R does not provide native support for labels. Some packages, however, have made this feature available. Most notably, the Hmisc package provides labelling methods for a number of different object. Due to design decisions, these methods are not all exported, and so are unavailable for use in package development. The labelVector package supports labels for atomic vectors in a light-weight design that is suitable for use in other packages.
Complete analytical environment for the construction and analysis of matrix population models and integral projection models. Includes the ability to construct historical matrices, which are 2d matrices comprising 3 consecutive times of demographic information. Estimates both raw and function-based forms of historical and standard ahistorical matrices. It also estimates function-based age-by-stage matrices and raw and function-based Leslie matrices.
When building complex models, it is often difficult to explain why the model should be trusted. While global measures such as accuracy are useful, they cannot be used for explaining why a model made a specific prediction. lime (a port of the lime Python package) is a method for explaining the outcome of black box models by fitting a local model around the point in question an perturbations of this point. The approach is described in more detail in the article by Ribeiro et al. (2016) <doi:10.48550/arXiv.1602.04938>.
When the values of the outcome variable Y are either 0 or 1, the function lsm() calculates the estimation of the log likelihood in the saturated model. This model is characterized by Llinas (2006, ISSN:2389-8976) in section 2.3 through the assumptions 1 and 2. The function LogLik() works (almost perfectly) when the number of independent variables K is high, but for small K it calculates wrong values in some cases. For this reason, when Y is dichotomous and the data are grouped in J populations, it is recommended to use the function lsm() because it works very well for all K.
Network analysis usually requires estimating the uncertainty of graph statistics. Through this package, we provide tools to bootstrap various networks via local bootstrap procedure. Additionally, it includes functions for generating probability matrices, creating network adjacency matrices from probability matrices, and plotting network structures. The reference will be updated soon.
This package provides functions to fit quantile regression models for hierarchical data (2-level nested designs) as described in Geraci and Bottai (2014, Statistics and Computing) <doi:10.1007/s11222-013-9381-9>. A vignette is given in Geraci (2014, Journal of Statistical Software) <doi:10.18637/jss.v057.i13> and included in the package documents. The packages also provides functions to fit quantile models for independent data and for count responses.
Converts table-like objects to stand-alone PDF or PNG. Can be used to embed tables and arbitrary content in PDF or Word documents. Provides a low-level R interface for creating LaTeX code, e.g. command() and a high-level interface for creating PDF documents, e.g. as.pdf.data.frame(). Extensive customization is available via mid-level functions, e.g. as.tabular(). See also package?latexpdf'. Support for PNG is experimental; see as.png.data.frame'. Adapted from metrumrg <https://r-forge.r-project.org/R/?group_id=1215>. Requires a compatible installation of pdflatex', e.g. <https://miktex.org/>.
LINCS L1000 is a high-throughput technology that allows the gene expression measurement in a large number of assays. However, to fit the measurements of ~1000 genes in the ~500 color channels of LINCS L1000, every two landmark genes are designed to share a single channel. Thus, a deconvolution step is required to infer the expression values of each gene. Any errors in this step can be propagated adversely to the downstream analyses. We present a LINCS L1000 data peak calling R package l1kdeconv based on a new outlier detection method and an aggregate Gaussian mixture model. Upon the remove of outliers and the borrowing information among similar samples, l1kdeconv shows more stable and better performance than methods commonly used in LINCS L1000 data deconvolution.