This package provides methods to test whether time series is consistent with white noise. Two new tests based on Haar wavelets and general wavelets described by Nason and Savchev (2014) <doi:10.1002/sta4.69> are provided and, for comparison purposes this package also implements the B test of Bartlett (1967) <doi:10.2307/2333850>. Functionality is provided to compute an approximation to the theoretical power of the general wavelet test in the case of general ARMA alternatives.

We use the Alternating Direction Method of Multipliers (ADMM) for parameter estimation in high-dimensional, single-modality mediation models. To improve the sensitivity and specificity of estimated mediation effects, we offer the sure independence screening (SIS) function for dimension reduction. The available penalty options include Lasso, Elastic Net, Pathway Lasso, and Network-constrained Penalty. The methods employed in the package are based on Boyd, S., Parikh, N., Chu, E., Peleato, B., & Eckstein, J. (2011). <doi:10.1561/2200000016>, Fan, J., & Lv, J. (2008) <doi:10.1111/j.1467-9868.2008.00674.x>, Li, C., & Li, H. (2008) <doi:10.1093/bioinformatics/btn081>, Tibshirani, R. (1996) <doi:10.1111/j.2517-6161.1996.tb02080.x>, Zhao, Y., & Luo, X. (2022) <doi:10.4310/21-sii673>, and Zou, H., & Hastie, T. (2005) <doi:10.1111/j.1467-9868.2005.00503.x>.

This package provides functions to perform dimensionality reduction for classification if the covariance matrices of the classes are unequal.

Analysis of plant pathogen pathotype survey data. Functions provided calculate distribution of susceptibilities, distribution of complexities with statistics, pathotype frequency distribution, as well as diversity indices for pathotypes. This package is meant to be a direct replacement for Herrmann, Löwer and Schachtel's (1999) <doi:10.1046/j.1365-3059.1999.00325.x> Habgood-Gilmour Spreadsheet, HaGiS', previously used for pathotype analysis.

Translation between experimental null hypotheses, hypothesis matrices, and contrast matrices as used in linear regression models. The package is based on the method described in Schad et al. (2019) <doi:10.1016/j.jml.2019.104038> and Rabe et al. (2020) <doi:10.21105/joss.02134>.

This package provides tools for processing and analyzing .har and .sl4 files, making it easier for GEMPACK users and GTAP researchers to handle large economic datasets. It simplifies the management of multiple experiment results, enabling faster and more efficient comparisons without complexity. Users can extract, restructure, and merge data seamlessly, ensuring compatibility across different tools. The processed data can be exported and used in R', Stata', Python', Julia', or any software that supports Text, CSV, or Excel formats.

Work with model files (setup, input, output) from the hydrological catchment model HYPE: Streamlined file import and export, standard evaluation plot routines, diverse post-processing and aggregation routines for hydrological model analysis. The HYPEtools package is also archived at <doi:10.5281/zenodo.7627955> and can be cited in publications with Brendel et al. (2024) <doi:10.1016/j.envsoft.2024.106094>.

This package provides interpretable high-dimensional mean comparison methods (HMC). For example, users can apply these methods to assess the difference in gene expression between two treatment groups. It is not a gene-by-gene comparison. Instead, the methods focus on the interplay between features and identify those that are predictive of the group label. The tests are valid frequentist procedures and yield sparse estimates indicating which features contribute to the group differences.

Comfortable ways to work with hyperspectral data sets. I.e. spatially or time-resolved spectra, or spectra with any other kind of information associated with each of the spectra. The spectra can be data as obtained in XRF, UV/VIS, Fluorescence, AES, NIR, IR, Raman, NMR, MS, etc. More generally, any data that is recorded over a discretized variable, e.g. absorbance = f(wavelength), stored as a vector of absorbance values for discrete wavelengths is suitable.

Fits Hierarchical Bayesian space-Time models for Gaussian data. Furthermore, its functions have been implemented for analysing the fitting qualities of those models.

These sample data sets are intended for historians learning R. They include population, institutional, religious, military, and prosopographical data suitable for mapping, quantitative analysis, and network analysis.

This package contains data for software hotspot analysis, along with a function performing the analysis itself.

This package provides tools for the estimation of Heckman selection models with robust variance-covariance matrices. It includes functions for computing the bread and meat matrices, as well as clustered standard errors for generalized Heckman models, see Fernando de Souza Bastos and Wagner Barreto-Souza and Marc G. Genton (2022, ISSN: <https://www.jstor.org/stable/27164235>). The package also offers cluster-robust inference with sandwich estimators, and tools for handling issues related to eigenvalues in covariance matrices.

Clustering of high dimensional data with Hidden Markov Model on Variable Blocks (HMM-VB) fitted via Baum-Welch algorithm. Clustering is performed by the Modal Baum-Welch algorithm (MBW), which finds modes of the density function. Lin Lin and Jia Li (2017) <https://jmlr.org/papers/v18/16-342.html>.

An implementation of the modelling and reporting features described in reference textbook and guidelines (Briggs, Andrew, et al. Decision Modelling for Health Economic Evaluation. Oxford Univ. Press, 2011; Siebert, U. et al. State-Transition Modeling. Medical Decision Making 32, 690-700 (2012).): deterministic and probabilistic sensitivity analysis, heterogeneity analysis, time dependency on state-time and model-time (semi-Markov and non-homogeneous Markov models), etc.

Pre-made models that can be rapidly tailored to various chemicals and species using chemical-specific in vitro data and physiological information. These tools allow incorporation of chemical toxicokinetics ("TK") and in vitro-in vivo extrapolation ("IVIVE") into bioinformatics, as described by Pearce et al. (2017) (<doi:10.18637/jss.v079.i04>). Chemical-specific in vitro data characterizing toxicokinetics have been obtained from relatively high-throughput experiments. The chemical-independent ("generic") physiologically-based ("PBTK") and empirical (for example, one compartment) "TK" models included here can be parameterized with in vitro data or in silico predictions which are provided for thousands of chemicals, multiple exposure routes, and various species. High throughput toxicokinetics ("HTTK") is the combination of in vitro data and generic models. We establish the expected accuracy of HTTK for chemicals without in vivo data through statistical evaluation of HTTK predictions for chemicals where in vivo data do exist. The models are systems of ordinary differential equations that are developed in MCSim and solved using compiled (C-based) code for speed. A Monte Carlo sampler is included for simulating human biological variability (Ring et al., 2017 <doi:10.1016/j.envint.2017.06.004>) and propagating parameter uncertainty (Wambaugh et al., 2019 <doi:10.1093/toxsci/kfz205>). Empirically calibrated methods are included for predicting tissue:plasma partition coefficients and volume of distribution (Pearce et al., 2017 <doi:10.1007/s10928-017-9548-7>). These functions and data provide a set of tools for using IVIVE to convert concentrations from high-throughput screening experiments (for example, Tox21, ToxCast) to real-world exposures via reverse dosimetry (also known as "RTK") (Wetmore et al., 2015 <doi:10.1093/toxsci/kfv171>).

Estimates frictional constants for hydraulic analysis of rivers. This HYDRaulic ROughness CALculator (HYDROCAL) was previously developed as a spreadsheet tool and accompanying documentation by McKay and Fischenich (2011, <https://erdc-library.erdc.dren.mil/jspui/bitstream/11681/2034/1/CHETN-VII-11.pdf>).

This package provides a collection of reweighted marginal hypothesis tests for clustered data, based on reweighting methods of Williamson, J., Datta, S., and Satten, G. (2003) <doi:10.1111/1541-0420.00005>. The tests in this collection are clustered analogs to well-known hypothesis tests in the classical setting, and are appropriate for data with cluster- and/or group-size informativeness. The syntax and output of functions are modeled after common, recognizable functions native to R. Methods used in the package refer to Gregg, M., Datta, S., and Lorenz, D. (2020) <doi:10.1177/0962280220928572>, Nevalainen, J., Oja, H., and Datta, S. (2017) <doi:10.1002/sim.7288> Dutta, S. and Datta, S. (2015) <doi:10.1111/biom.12447>, Lorenz, D., Datta, S., and Harkema, S. (2011) <doi:10.1002/sim.4368>, Datta, S. and Satten, G. (2008) <doi:10.1111/j.1541-0420.2007.00923.x>, Datta, S. and Satten, G. (2005) <doi:10.1198/016214504000001583>.

Computes heteroskedasticity-consistent covariance matrix estimators for ordinary least squares regression models. The published HC0 through HC5m estimators implemented in the package follow White (1980) <doi:10.2307/1912934>, Hinkley (1977) <doi:10.1080/00401706.1977.10489550>, Horn et al. (1975) <doi:10.1080/01621459.1975.10479877>, MacKinnon and White (1985) <doi:10.1016/0304-4076(85)90158-7>, Cribari-Neto (2004) <doi:10.1016/S0167-9473(02)00366-3>, Cribari-Neto and da Silva (2011) <doi:10.1007/s10182-010-0141-2>, Cribari-Neto et al. (2007) <doi:10.1080/03610920601126589>, and Li et al. (2016) <doi:10.1080/00949655.2016.1198906>. The package also includes HCbeta, a new estimator proposed by the package authors. It provides normal Wald tests, confidence intervals, diagnostics, and S3 output for applied inference.

Seed germinates through the physical process of water uptake by dry seed driven by the difference in water potential between the seed and the water. There exists seed-to-seed variability in the base seed water potential. Hence, there is a need for a distribution such that a viable seed with its base seed water potential germinates if and only if the soil water potential is more than the base seed water potential. This package estimates the stress tolerance and uniformity parameters of the seed lot for germination under various temperatures by using the hydro-time model of counts of germinated seeds under various water potentials. The distribution of base seed water potential has been considered to follow Normal, Logistic and Extreme value distribution. The estimated proportion of germinated seeds along with the estimates of stress and uniformity parameters are obtained using a generalised linear model. The significance test of the above parameters for within and between temperatures is also performed in the analysis. Details can be found in Kebreab and Murdoch (1999) <doi:10.1093/jxb/50.334.655> and Bradford (2002) <https://www.jstor.org/stable/4046371>.

An S4 class and several functions which utilize internally stored datasets and gauging data enable 1d water level interpolation. The S4 class (WaterLevelDataFrame) structures the computation and visualisation of 1d water level information along the German federal waterways Elbe and Rhine. hyd1d delivers 1d water level data - extracted from the FLYS database - and validated gauging data - extracted from the hydrological database WISKI7 - package-internally. For computations near real time gauging data are queried externally from the PEGELONLINE REST API <https://pegelonline.wsv.de/webservice/dokuRestapi>.

Unsupervised multivariate filter feature selection using the UFS-rHCM or UFS-cHCM algorithms based on the heterogeneous correlation matrix (HCM). The HCM consists of Pearson's correlations between numerical features, polyserial correlations between numerical and ordinal features, and polychoric correlations between ordinal features. Tortora C., Madhvani S., Punzo A. (2025). "Designing unsupervised mixed-type feature selection techniques using the heterogeneous correlation matrix." International Statistical Review <doi:10.1111/insr.70016>. This work was supported by the National Science foundation NSF Grant N 2209974 (Tortora) and by the Italian Ministry of University and Research (MUR) under the PRIN 2022 grant number 2022XRHT8R (CUP: E53D23005950006), as part of â The SMILE Project: Statistical Modelling and Inference to Live the Environmentâ , funded by the European Union â Next Generation EU (Punzo).

This package provides a data set of the Portuguese NHS hospitals.

An RStudio Addin for Hippie Expand (AKA Hippie Code Completion or Cyclic Expand Word). This type of completion searches for matching tokens within the user's current source editor file, regardless of file type. By searching only within the current source file, hippie offers a fast way to identify and insert completions that appear around the user's cursor.