This package performs exact rate ratio tests.

Partitions the phenotypic variance of a plastic trait, studied through its reaction norm. The variance partition distinguishes between the variance arising from the average shape of the reaction norms (V_Plas) and the (additive) genetic variance . The latter is itself separated into an environment-blind component (V_G/V_A) and the component arising from plasticity (V_GxE/V_AxE). The package also provides a way to further partition V_Plas into aspects (slope/curvature) of the shape of the average reaction norm (pi-decomposition) and partition V_Add (gamma-decomposition) and V_AxE (iota-decomposition) into the impact of genetic variation in the reaction norm parameters. Reference: de Villemereuil & Chevin (2025) <doi:10.32942/X2NC8B>.

This package provides a complete seven-step workflow for copy number variation (CNV) analysis applicable to any disease or condition where samples with genomic copy number data is available. Supports built-in grading and risk stratification presets for seven major cancers (viz. prostate, breast, colorectal, lung, cervical, lymphoma, melanoma) based on clinically validated systems including ISUP Grade Groups, Nottingham Grading System, Dukes staging, IASLC TNM, FIGO, Ann Arbor/Lugano classification, and Breslow depth. Generalizable to other disease types. An automatic mode derives a normalised Risk Score from the data using min-max normalisation and adaptive binning. Custom user-defined thresholds are supported for any other disease type. Downstream functions for CNV aberration detection, recurrence analysis, gene annotation, CNV matrix generation, and CNV-RNA expression correlation are disease-type agnostic.

Download the lyrics of your favorite songs in text and table formats. Also search for related songs or song information. More information: <https://docs.genius.com/> .

PaleoClim <http://www.paleoclim.org> (Brown et al. 2019, <doi:10.1038/sdata.2018.254>) is a set of free, high resolution paleoclimate surfaces covering the whole globe. It includes data on surface temperature, precipitation and the standard bioclimatic variables commonly used in ecological modelling, derived from the HadCM3 general circulation model and downscaled to a spatial resolution of up to 2.5 minutes. Simulations are available for key time periods from the Late Holocene to mid-Pliocene. Data on current and Last Glacial Maximum climate is derived from CHELSA (Karger et al. 2017, <doi:10.1038/sdata.2017.122>) and reprocessed by PaleoClim to match their format; it is available at up to 30 seconds resolution. This package provides a simple interface for downloading PaleoClim data in R, with support for caching and filtering retrieved data by period, resolution, and geographic extent.

The SPRITE algorithm creates possible distributions of discrete responses based on reported sample parameters, such as mean, standard deviation and range (Heathers et al., 2018, <doi:10.7287/peerj.preprints.26968v1>). This package implements it, drawing heavily on the code for Nick Brown's rSPRITE Shiny app <https://shiny.ieis.tue.nl/sprite/>. In addition, it supports the modeling of distributions based on multi-item (Likert-type) scales and the use of restrictions on the frequency of particular responses.

Calculates robust Matthews Correlation Coefficient (MCC) and robust F-Beta Scores, as introduced by Holzmann and Klar (2024) <doi:10.48550/arXiv.2404.07661>. These performance metrics are designed for imbalanced classification problems. Plots the receiver operating characteristic curve (ROC curve) together with the recall / 1-precision curve.

Generate random user data from the Random User Generator API. For more information, see <https://randomuser.me/>.

Computation of one-, two- and three-dimensional pseudo-observations based on recurrent events and terminal events. Generalised linear models are fitted using generalised estimating equations. Technical details on the bivariate procedure can be found in "Bivariate pseudo-observations for recurrent event analysis with terminal events" (Furberg et al., 2021) <doi:10.1007/s10985-021-09533-5>.

Defines colour palettes and themes for Royal Statistical Society (RSS) publications, including Significance magazine. Palettes and themes are supported in both base R and ggplot2 graphics, and are intended to be used by authors submitting to RSS publications.

This package provides R bindings for Tabulator JS <https://tabulator.info/>. Makes it a breeze to create highly customizable interactive tables in rmarkdown documents and shiny applications. It includes filtering, grouping, editing, input validation, history recording, column formatters, packaged themes and more.

Defines storage standard for Read, process, and analyze intracranial electroencephalography and deep-brain stimulation in RAVE', a reproducible framework for analysis and visualization of iEEG by Magnotti, Wang, and Beauchamp, (2020, <doi:10.1016/j.neuroimage.2020.117341>). Supports brain imaging data structure (BIDS) <https://bids.neuroimaging.io> and native file structure to ingest signals from Matlab data files, hierarchical data format 5 (HDF5), European data format (EDF), BrainVision core data format (BVCDF), or BlackRock Microsystem (NEV/NSx); process images in Neuroimaging informatics technology initiative (NIfTI) and FreeSurfer formats, providing brain imaging normalization to template brain, facilitating threeBrain package for comprehensive electrode localization via YAEL (your advanced electrode localizer) by Wang, Magnotti, Zhang, and Beauchamp (2023, <doi:10.1523/ENEURO.0328-23.2023>).

Allows caching of raw data directly in R code. This allows R scripts and R Notebooks to be shared and re-run on a machine without access to the original data. Cached data is encoded into an ASCII string that can be pasted into R code. When the code is run, the data is automatically loaded from the cached version if the original data file is unavailable. Works best for small datasets (a few hundred observations).

Formats for R Markdown that undo modifications by pandoc and rmarkdown to original latex templates, such as smaller margins, paragraph spacing, and compact titles. In addition, enhancements such as author blocks with affiliations and headers and footers are introduced. All of this functionality is built around plugins that modify the default pandoc template without relying on custom templates.

This package performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are Method A / Method B and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (South Africa: Cmax) - is implemented as well.

An approach to age-depth modelling that uses Bayesian statistics to reconstruct accumulation histories for deposits, through combining radiocarbon and other dates with prior information on accumulation rates and their variability. See Blaauw & Christen (2011).

Rasterize images using a 3D software renderer. 3D scenes are created either by importing external files, building scenes out of the included objects, or by constructing meshes manually. Supports point and directional lights, anti-aliased lines, shadow mapping, transparent objects, translucent objects, multiple materials types, reflection, refraction, environment maps, multicore rendering, bloom, tone-mapping, and screen-space ambient occlusion.

Listings are often part of the submission of clinical trial data in regulatory settings. We provide a framework for the specific formatting features often used when displaying large datasets in that context.

Load multiple movies, series, actors, directors etc from OMDB API. More information in: <http://www.omdbapi.com/> .

This package provides a dependency-light OpenTimelineIO (OTIO) <https://github.com/AcademySoftwareFoundation/OpenTimelineIO> document layer in pure R. Provides constructors for the OTIO object model (timelines, tracks, clips, gaps, media references, rational times and time ranges), functional builders that return new objects, and readers and writers for canonical .otio files through jsonlite'. The optional RcppOTIO package validates output against the real OpenTimelineIO C++ library. No compiled code.

Various tools for handling fuzzy measures, calculating Shapley value and interaction index, Choquet and Sugeno integrals, as well as fitting fuzzy measures to empirical data are provided. Construction of fuzzy measures from empirical data is done by solving a linear programming problem by using lpsolve package, whose source in C adapted to the R environment is included. The description of the basic theory of fuzzy measures is in the manual in the Doc folder in this package. Please refer to the following: [1] <https://personal-sites.deakin.edu.au/~gleb/fmtools.html> [2] G. Beliakov, H. Bustince, T. Calvo, A Practical Guide to Averaging', Springer, (2016, ISBN: 978-3-319-24753-3). [3] G. Beliakov, S. James, J-Z. Wu, Discrete Fuzzy Measures', Springer, (2020, ISBN: 978-3-030-15305-2).

Calculate rarefaction-based alpha- and beta-diversity. Offer parametric extrapolation to estimate the total expected species in a single community and the total expected shared species between two communities. Visualize the curve-fitting for these estimators.

Useful tools for determining whether two samples are from the same distribution. Utilizes a robust method to address the problematic structure of the similarity graph constructed from high-dimensional data. The method is provided in Yichuan Bai and Lynna Chu (2023) <arXiv:2307.12325>.

Some survey participants tend to respond carelessly which complicates data analysis. This package provides functions that make it easier to explore responses and identify those that may be problematic. See Gottfried et al. (2022) <doi:10.7275/vyxb-gt24> for more information.