Download data from the Ada and Archibald MacLeish Field Station in Whately, MA. The Ada and Archibald MacLeish Field Station is a 260-acre patchwork of forest and farmland located in West Whately, MA that provides opportunities for faculty and students to pursue environmental research, outdoor education, and low-impact recreation (see <https://www.smith.edu/discover-smith/smith-action/sustainable-smith/macleish-field-station> for more information). This package contains weather data over several years, and spatial data on various man-made and natural structures.

Mass measurement corrections and uncertainties using calibration data, as recommended by EURAMET's guideline No. 18 (2015) ISBN:978-3-942992-40-4 . The package provides classes, functions, and methods for storing information contained in calibration certificates and converting balance readings to both conventional mass and real mass. For the latter, the Magnitude of the Air Buoyancy Correction factor employs models (such as the CIMP-2007 formula revised by Picard, Davis, Gläser, and Fujii (2008) <doi:10.1088/0026-1394/45/2/004>) to estimate the local air density using measured environmental conditions.

Compute important quantities when we consider stochastic systems that are observed continuously. Such as, Cost model, Limiting distribution, Transition matrix, Transition distribution and Occupancy matrix. The methods are described, for example, Ross S. (2014), Introduction to Probability Models. Eleven Edition. Academic Press.

Power analysis and sample size calculation for Welch and Hsu (Hedderich and Sachs (2018), ISBN:978-3-662-56657-2) t-tests including Monte-Carlo simulations of empirical power and type-I-error. Power and sample size calculation for Wilcoxon rank sum and signed rank tests via Monte-Carlo simulations. Power and sample size required for the evaluation of a diagnostic test(-system) (Flahault et al. (2005), <doi:10.1016/j.jclinepi.2004.12.009>; Dobbin and Simon (2007), <doi:10.1093/biostatistics/kxj036>) as well as for a single proportion (Fleiss et al. (2003), ISBN:978-0-471-52629-2; Piegorsch (2004), <doi:10.1016/j.csda.2003.10.002>; Thulin (2014), <doi:10.1214/14-ejs909>), comparing two negative binomial rates (Zhu and Lakkis (2014), <doi:10.1002/sim.5947>), ANCOVA (Shieh (2020), <doi:10.1007/s11336-019-09692-3>), reference ranges (Jennen-Steinmetz and Wellek (2005), <doi:10.1002/sim.2177>), multiple primary endpoints (Sozu et al. (2015), ISBN:978-3-319-22005-5), and AUC (Hanley and McNeil (1982), <doi:10.1148/radiology.143.1.7063747>).

Three estimating equation methods are provided in this package for marginal analysis of longitudinal ordinal data with misclassified responses and covariates. The naive analysis which is solely based on the observed data without adjustment may lead to bias. The corrected generalized estimating equations (GEE2) method which is unbiased requires the misclassification parameters to be known beforehand. The corrected generalized estimating equations (GEE2) with validation subsample method estimates the misclassification parameters based on a given validation set. This package is an implementation of Chen (2013) <doi:10.1002/bimj.201200195>.

This package provides a tool to simulate salmon metapopulations and apply financial portfolio optimization concepts. The package accompanies the paper Anderson et al. (2015) <doi:10.1101/2022.03.24.485545>.

This package provides functions for dimension reduction, using MAVE (Minimum Average Variance Estimation), OPG (Outer Product of Gradient) and KSIR (sliced inverse regression of kernel version). Methods for selecting the best dimension are also included. Xia (2002) <doi:10.1111/1467-9868.03411>; Xia (2007) <doi:10.1214/009053607000000352>; Wang (2008) <doi:10.1198/016214508000000418>.

Function multiroc() can be used for computing and visualizing Receiver Operating Characteristics (ROC) and Area Under the Curve (AUC) for multi-class classification problems. It supports both One-vs-One approach by M.Bishop, C. (2006, ISBN:978-0-387-31073-2) and One-vs-All approach by Murphy P., K. (2012, ISBN:9780262018029).

Automatically estimate 11 effect size measures from a well-formatted dataset. Various other functions can help, for example, removing dependency between several effect sizes, or identifying differences between two datasets. This package is mainly designed to assist in conducting a systematic review with a meta-analysis but can be useful to any researcher interested in estimating an effect size.

This package provides functions to calculate the minimum and maximum possible values of Cronbach's alpha when item-level missing data are present. Cronbach's alpha (Cronbach, 1951 <doi:10.1007/BF02310555>) is one of the most widely used measures of internal consistency in the social, behavioral, and medical sciences (Bland & Altman, 1997 <doi:10.1136/bmj.314.7080.572>; Tavakol & Dennick, 2011 <doi:10.5116/ijme.4dfb.8dfd>). However, conventional implementations assume complete data, and listwise deletion is often applied when missingness occurs, which can lead to biased or overly optimistic reliability estimates (Enders, 2003 <doi:10.1037/1082-989X.8.3.322>). This package implements computational strategies including enumeration, Monte Carlo sampling, and optimization algorithms (e.g., Genetic Algorithm, Differential Evolution, Sequential Least Squares Programming) to obtain sharp lower and upper bounds of Cronbach's alpha under arbitrary missing data patterns. The approach is motivated by Manski's partial identification framework and pessimistic bounding ideas from optimization literature.

This package provides a collection of miscellaneous helper function for running multilevel/mixed models in lme4'. This package aims to provide functions to compute common tasks when estimating multilevel models such as computing the intraclass correlation and design effect, centering variables, estimating the proportion of variance explained at each level, pseudo-R squared, random intercept and slope reliabilities, tests for homogeneity of variance at level-1, and cluster robust and bootstrap standard errors. The tests and statistics reported in the package are from Raudenbush & Bryk (2002, ISBN:9780761919049), Hox et al. (2018, ISBN:9781138121362), and Snijders & Bosker (2012, ISBN:9781849202015).

Correlation coefficients for multivariate data, namely the squared correlation coefficient and the RV coefficient (multivariate generalization of the squared Pearson correlation coefficient). References include Mardia K.V., Kent J.T. and Bibby J.M. (1979). "Multivariate Analysis". ISBN: 978-0124712522. London: Academic Press.

This package implements the Multi-Objective Clustering Algorithm Guided by a-Priori Biological Knowledge (MOC-GaPBK) which was proposed by Parraga-Alava, J. et. al. (2018) <doi:10.1186/s13040-018-0178-4>.

Algorithms to build set partitions and commutator matrices and their use in the construction of multivariate d-Hermite polynomials; estimation and derivation of theoretical vector moments and vector cumulants of multivariate distributions; conversion formulae for multivariate moments and cumulants. Applications to estimation and derivation of multivariate measures of skewness and kurtosis; estimation and derivation of asymptotic covariances for d-variate Hermite polynomials, multivariate moments and cumulants and measures of skewness and kurtosis. The formulae implemented are discussed in Terdik (2021, ISBN:9783030813925), "Multivariate Statistical Methods".

This package provides a set of functions, classes and methods for performing ABC and ABC/XYZ analyses, identifying overperforming, underperforming and constantly performing items, and plotting, analyzing as well as predicting the temporal development of items.

This function allows to generate two biological conditions synthetic microarray dataset which has similar behavior to those currently observed with common platforms. User provides a subset of parameters. Available default parameters settings can be modified.

This package performs (simultaneous) inferences for ratios of linear combinations of coefficients in the general linear model, linear mixed model, and for quantiles in a one-way layout. Multiple comparisons and simultaneous confidence interval estimations can be performed for ratios of treatment means in the normal one-way layout with homogeneous and heterogeneous treatment variances, according to Dilba et al. (2007) <https://cran.r-project.org/doc/Rnews/Rnews_2007-1.pdf> and Hasler and Hothorn (2008) <doi:10.1002/bimj.200710466>. Confidence interval estimations for ratios of linear combinations of linear model parameters like in (multiple) slope ratio and parallel line assays can be carried out. Moreover, it is possible to calculate the sample sizes required in comparisons with a control based on relative margins. For the simple two-sample problem, functions for a t-test for ratio-formatted hypotheses and the corresponding confidence interval are provided assuming homogeneous or heterogeneous group variances.

R interface to MLflow', open source platform for the complete machine learning life cycle, see <https://mlflow.org/>. This package supports installing MLflow', tracking experiments, creating and running projects, and saving and serving models.

The temporal relationship between motor neurons can offer explanations for neural strategies. We combined functions to reduce neuron action potential discharge data and analyze it for short-term, time-domain synchronization. Even more so, motoRneuron combines most available methods for the determining cross correlation histogram peaks and most available indices for calculating synchronization into simple functions. See Nordstrom, Fuglevand, and Enoka (1992) <doi:10.1113/jphysiol.1992.sp019244> for a more thorough introduction.

Identify and rank CpG DNA methylation conservation along the human genome. Specifically it includes bootstrapping methods to provide ranking which should adjust for the differences in length as without it short regions tend to get higher conservation scores.

Mask ranges based on expert knowledge or remote sensing layers. These tools can be combined to quantitatively and reproducibly generate a new map or to update an existing map. Methods include expert opinion and data-driven tools to generate thresholds for binary masks.

Density computation, random matrix generation and maximum likelihood estimation of the matrix normal distribution. References: Pocuca N., Gallaugher M. P., Clark K. M. & McNicholas P. D. (2019). Assessing and Visualizing Matrix Variate Normality. <doi:10.48550/arXiv.1910.02859> and the relevant wikipedia page.

This package provides a new method to implement clustering from multiple modality data of certain samples, the function M2SMjF() jointly factorizes multiple similarity matrices into a shared sub-matrix and several modality private sub-matrices, which is further used for clustering. Along with this method, we also provide function to calculate the similarity matrix and function to evaluate the best cluster number from the original data.

Offering enhanced statistical power compared to traditional hypothesis testing methods, informative hypothesis testing allows researchers to explicitly model their expectations regarding the relationships among parameters. An important software tool for this framework is restriktor'. The mmirestriktor package provides shiny web applications to implement some of the basic functionality of restriktor'. The mmirestriktor() function launches a shiny application for fitting and analyzing models with constraints. The FbarCards() function launches a card game application which can help build intuition about informative hypothesis testing. The iht_interpreter() helps interpret informative hypothesis testing results based on guidelines in Vanbrabant and Rosseel (2020) <doi:10.4324/9780429273872-14>.