Application of a test to rule out that trends detected in hydrological time series are explained exclusively by the randomness of the climate. Based on: Ricchetti, (2018) <https://repositorio.uchile.cl/handle/2250/168487>.

This package provides methods to analyze cluster alternatives based on multi-objective optimization of cluster validation indices. For details see Kraus et al. (2011) <doi:10.1007/s00180-011-0244-6>.

This package implements likelihood inference based on higher order approximations for linear nonnormal regression models.

This package provides an interface to OpenML.org to list and download machine learning data, tasks and experiments. The OpenML objects can be automatically converted to mlr3 objects. For a more sophisticated interface with more upload options, see the OpenML package.

Projection based methods for preprocessing, exploring and analysis of multivariate data used in chemometrics. S. Kucheryavskiy (2020) <doi:10.1016/j.chemolab.2020.103937>.

This package provides implementations of functions that can be used to test multivariate integration routines. The package covers six different integration domains (unit hypercube, unit ball, unit sphere, standard simplex, non-negative real numbers and R^n). For each domain several functions with different properties (smooth, non-differentiable, ...) are available. The functions are available in all dimensions n >= 1. For each function the exact value of the integral is known and implemented to allow testing the accuracy of multivariate integration routines. Details on the available test functions can be found at on the development website.

This package provides functions to compute and plot multivariate (partial) Mantel correlograms.

Multivariate Surrogate Synchrony ('mvSUSY') estimates the synchrony within datasets that contain more than two time series. mvSUSY was developed from Surrogate Synchrony ('SUSY') with respect to implementing surrogate controls, and extends synchrony estimation to multivariate data. mvSUSY works as described in Meier & Tschacher (2021).

This package provides matrix Gaussian mixture models, matrix transformation mixture models and their model-based clustering results. The parsimonious models of the mean matrices and variance covariance matrices are implemented with a total of 196 variations. For more information, please check: Xuwen Zhu, Shuchismita Sarkar, and Volodymyr Melnykov (2021), "MatTransMix: an R package for matrix model-based clustering and parsimonious mixture modeling", <doi:10.1007/s00357-021-09401-9>.

There are two functions-meta2d and meta3d for detecting rhythmic signals from time-series datasets. For analyzing time-series datasets without individual information, meta2d is suggested, which could incorporates multiple methods from ARSER, JTK_CYCLE and Lomb-Scargle in the detection of interested rhythms. For analyzing time-series datasets with individual information, meta3d is suggested, which takes use of any one of these three methods to analyze time-series data individual by individual and gives out integrated values based on analysis result of each individual.

Fits the neighboring models of a fitted structural equation model and assesses the model uncertainty of the fitted model based on BIC posterior probabilities, using the method presented in Wu, Cheung, and Leung (2020) <doi:10.1080/00273171.2019.1574546>.

This package provides a toolbox to handle and represent trophic networks in space or time across aggregation levels. This package contains a layout algorithm specifically designed for trophic networks, using dimension reduction on a diffusion graph kernel and trophic levels. Importantly, this package provides a layout method applicable for large trophic networks.

This package provides methods for analyzing DNA methylation data via Most Recurrent Methylation Patterns (MRMPs). Supports cell-type annotation, spatial deconvolution, unsupervised clustering, and cancer cell-of-origin inference. Includes C-backed summaries for YAME â .cg/.cmâ files (overlap counts, log2 odds ratios, beta/depth aggregation), an XGBoost classifier, NNLS deconvolution, and plotting utilities. Scales to large spatial and single-cell methylomes and is robust to extreme sparsity.

This package provides functions that fit two modern education-based value-added models. One of these models is the quantile value-added model. This model permits estimating a school's value-added based on specific quantiles of the post-test distribution. Estimating value-added based on quantiles of the post-test distribution provides a more complete picture of an education institution's contribution to learning for students of all abilities. See Page, G.L.; San Martà n, E.; Orellana, J.; Gonzalez, J. (2017) <doi:10.1111/rssa.12195> for more details. The second model is a temporally dependent value-added model. This model takes into account the temporal dependence that may exist in school performance between two cohorts in one of two ways. The first is by modeling school random effects with a non-stationary AR(1) process. The second is by modeling school effects based on previous cohort's post-test performance. In addition to more efficiently estimating value-added, this model permits making statements about the persistence of a schools effectiveness. The standard value-added model is also an option.

This package provides the Augmented Dickey-Fuller test and its variations to check the existence of bubbles (explosive behavior) for time series, based on the article by Peter C. B. Phillips, Shuping Shi and Jun Yu (2015a) <doi:10.1111/iere.12131>. Some functions may take a while depending on the size of the data used, or the number of Monte Carlo replications applied.

Analysis of experimental multi-parent populations to detect regions of the genome (called quantitative trait loci, QTLs) influencing phenotypic traits measured in unique and multiple environments. The population must be composed of crosses between a set of at least three parents (e.g. factorial design, diallel', or nested association mapping). The functions cover data processing, QTL detection, and results visualization. The implemented methodology is described in Garin, Wimmer, Mezmouk, Malosetti and van Eeuwijk (2017) <doi:10.1007/s00122-017-2923-3>, in Garin, Malosetti and van Eeuwijk (2020) <doi: 10.1007/s00122-020-03621-0>, and in Garin, Diallo, Tekete, Thera, ..., and Rami (2024) <doi: 10.1093/genetics/iyae003>.

This package provides tools for cleaning, processing, and preparing microbiome sequencing data (e.g., 16S rRNA) for downstream analysis. Supports CSV, TXT, and Excel file formats. The main function, ezclean(), automates microbiome data transformation, including format validation, transposition, numeric conversion, and metadata integration. It also handles taxonomic levels efficiently, resolves duplicated taxa entries, and outputs a well-structured, analysis-ready dataset. The companion functions ezstat() run statistical tests and summarize results, while ezviz() produces publication-ready visualizations.

It can be used to create/encode molecular "license-plates" from sequences and to also decode the "license-plates" back to sequences. While initially created for transfer RNA-derived small fragments (tRFs), this tool can be used for any genomic sequences including but not limited to: tRFs, microRNAs, etc. The detailed information can reference to Pliatsika V, Loher P, Telonis AG, Rigoutsos I (2016) <doi:10.1093/bioinformatics/btw194>. It can also be used to annotate tRFs. The detailed information can reference to Loher P, Telonis AG, Rigoutsos I (2017) <doi:10.1038/srep41184>.

Complex niche models show low performance in identifying the most important range-limiting environmental variables and in transferring habitat suitability to novel environmental conditions (Warren and Seifert, 2011 <DOI:10.1890/10-1171.1>; Warren et al., 2014 <DOI:10.1111/ddi.12160>). This package helps to identify the most important set of uncorrelated variables and to fine-tune Maxent's regularization multiplier. In combination, this allows to constrain complexity and increase performance of Maxent niche models (assessed by information criteria, such as AICc (Akaike, 1974 <DOI:10.1109/TAC.1974.1100705>), and by the area under the receiver operating characteristic (AUC) (Fielding and Bell, 1997 <DOI:10.1017/S0376892997000088>). Users of this package should be familiar with Maxent niche modelling.

This package implements Multi-Group Sparse Discriminant Analysis proposal of I.Gaynanova, J.Booth and M.Wells (2016), Simultaneous sparse estimation of canonical vectors in the p>>N setting, JASA <doi:10.1080/01621459.2015.1034318>.

Visualize the relationship between linear regression variables and causes of multi-collinearity. Implements the method in Lin et. al. (2020) <doi:10.1080/10618600.2020.1779729>.

Hypothesis tests for multivariate data. Tests for one and two mean vectors, multivariate analysis of variance, tests for one, two or more covariance matrices. References include: Mardia K.V., Kent J.T. and Bibby J.M. (1979). Multivariate Analysis. ISBN: 978-0124712522. London: Academic Press.

This package provides functions for metabolomics data analysis: data preprocessing, orthogonal signal correction, PCA analysis, PCA-DA analysis, PLS-DA analysis, classification, feature selection, correlation analysis, data visualisation and re-sampling strategies.

Many useful functions and extensions for dealing with meteorological data in the tidy data framework. Extends ggplot2 for better plotting of scalar and vector fields and provides commonly used analysis methods in the atmospheric sciences.