Shiny web application to run meta-analyses. Essentially a graphical front-end to package meta for R. Can be useful as an educational tool, and for quickly analyzing and sharing meta-analyses. Provides output to quickly fill in GRADE (Grading of Recommendations, Assessment, Development and Evaluations) Summary-of-Findings tables. Importantly, it allows further processing of the results inside R, in case more specific analyses are needed.

Nonparametric approach to estimate the location of block boundaries (change-points) of non-overlapping blocks in a random symmetric matrix which consists of random variables whose distribution changes from block to block. BRAULT Vincent, OUADAH Sarah, SANSONNET Laure and LEVY-LEDUC Celine (2017) <doi:10.1016/j.jmva.2017.12.005>.

The second version (0.2.0) contains implementation for exact matching which is an alternative to propensity score matching (see Glimm & Yau (2025)). The initial version (0.1.2) contains a collection of easy-to-implement tools for checking whether a MAIC can be conducted, as well as an alternative way of calculating weights (see Glimm & Yau (2021) <doi:10.1002/pst.2210>.).

Multivariate ARIMA and ARIMA-X estimation using Spliid's algorithm (marima()) and simulation (marima.sim()).

Counting process structure is fundamental to model time varying covariates. This package restructures dataframes in the counting process format for one or more variables. F. W. Dekker, et al. (2008) <doi:10.1038/ki.2008.328>.

Integrates fairness auditing and bias mitigation methods for the mlr3 ecosystem. This includes fairness metrics, reporting tools, visualizations and bias mitigation techniques such as "Reweighing" described in Kamiran, Calders (2012) <doi:10.1007/s10115-011-0463-8> and "Equalized Odds" described in Hardt et al. (2016) <https://papers.nips.cc/paper/2016/file/9d2682367c3935defcb1f9e247a97c0d-Paper.pdf>. Integration with mlr3 allows for auditing of ML models as well as convenient joint tuning of machine learning algorithms and debiasing methods.

Do multilevel mediation analysis with generalized additive multilevel models. The analysis method is described in Yu and Li (2020), "Third-Variable Effect Analysis with Multilevel Additive Models", PLoS ONE 15(10): e0241072.

Balancing quasi-experimental field research for effects of covariates is fundamental for drawing causal inference. Propensity Score Matching deals with this issue but current techniques are restricted to binary treatment variables. Moreover, they provide several solutions without providing a comprehensive framework on choosing the best model. The MAGMA R-package addresses these restrictions by offering nearest neighbor matching for two to four groups. It also includes the option to match data of a 2x2 design. In addition, MAGMA includes a framework for evaluating the post-matching balance. The package includes functions for the matching process and matching reporting. We provide a tutorial on MAGMA as vignette. More information on MAGMA can be found in Feuchter, M. D., Urban, J., Scherrer V., Breit, M. L., and Preckel F. (2022) <https://osf.io/p47nc/>.

This package provides tools for the analysis of psychophysical data in R. This package allows to estimate the Point of Subjective Equivalence (PSE) and the Just Noticeable Difference (JND), either from a psychometric function or from a Generalized Linear Mixed Model (GLMM). Additionally, the package allows plotting the fitted models and the response data, simulating psychometric functions of different shapes, and simulating data sets. For a description of the use of GLMMs applied to psychophysical data, refer to Moscatelli et al. (2012).

Matrix is an universal and sometimes primary object/unit in applied mathematics and statistics. We provide a number of algorithms for selected problems in optimization and statistical inference. For general exposition to the topic with focus on statistical context, see the book by Banerjee and Roy (2014, ISBN:9781420095388).

Various affine invariant multivariate normality tests are provided. It is designed to accompany the survey article Ebner, B. and Henze, N. (2020) <arXiv:2004.07332> titled "Tests for multivariate normality -- a critical review with emphasis on weighted L^2-statistics". We implement new and time honoured L^2-type tests of multivariate normality, such as the Baringhaus-Henze-Epps-Pulley (BHEP) test, the Henze-Zirkler test, the test of Henze-Jiménes-Gamero, the test of Henze-Jiménes-Gamero-Meintanis, the test of Henze-Visage, the Dörr-Ebner-Henze test based on harmonic oscillator and the Dörr-Ebner-Henze test based on a double estimation in a PDE. Secondly, we include the measures of multivariate skewness and kurtosis by Mardia, Koziol, Malkovich and Afifi and Móri, Rohatgi and Székely, as well as the associated tests. Thirdly, we include the tests of multivariate normality by Cox and Small, the energy test of Székely and Rizzo, the tests based on spherical harmonics by Manzotti and Quiroz and the test of Pudelko. All the functions and tests need the data to be a n x d matrix where n is the samplesize (number of rows) and d is the dimension (number of columns).

Straightforward and detailed evaluation of machine learning models. MLeval can produce receiver operating characteristic (ROC) curves, precision-recall (PR) curves, calibration curves, and PR gain curves. MLeval accepts a data frame of class probabilities and ground truth labels, or, it can automatically interpret the Caret train function results from repeated cross validation, then select the best model and analyse the results. MLeval produces a range of evaluation metrics with confidence intervals.

Data and code for the paper by Ehm, Gneiting, Jordan and Krueger ('Of Quantiles and Expectiles: Consistent Scoring Functions, Choquet Representations, and Forecast Rankings', JRSS-B, 2016 <DOI:10.1111/rssb.12154>).

Traditional methods typically detect breakpoints from individual signals, which means that when applied separately to multiple signals, the breakpoints are not aligned. However, this package implements a common breakpoint detection approach for multiple piecewise constant signals, resulting in increased detection sensitivity and specificity. By employing various techniques, optimal performance is ensured, and computation is accelerated. We hope that this package will be beneficial for researchers in signal processing, bioinformatics, economy, and other related fields. The segmentation(), lambda_estimator() functions are the main functions of this package.

Fit Bayesian stochastic block models (SBMs) and multi-level stochastic block models (MLSBMs) using efficient Gibbs sampling implemented in Rcpp'. The models assume symmetric, non-reflexive graphs (no self-loops) with unweighted, binary edges. Data are input as a symmetric binary adjacency matrix (SBMs), or list of such matrices (MLSBMs).

This package contains functions for mapping odds ratios, hazard ratios, or other effect estimates using individual-level data such as case-control study data, using generalized additive models (GAMs) or Cox models for smoothing with a two-dimensional predictor (e.g., geolocation or exposure to chemical mixtures) while adjusting linearly for confounding variables, using methods described by Kelsall and Diggle (1998), Webster at al. (2006), and Bai et al. (2020). Includes convenient functions for mapping point estimates and confidence intervals, efficient control sampling, and permutation tests for the null hypothesis that the two-dimensional predictor is not associated with the outcome variable (adjusting for confounders).

You can use the set of wrappers for analytical schemata to reduce the effort in writing machine-readable data. The set of all-in-one wrappers will cover widely used functions from data analysis packages.

This package provides the users with the ability to quickly create linked micromap plots for a collection of geographic areas. Linked micromap plots are visualizations of geo-referenced data that link statistical graphics to an organized series of small maps or graphic images. The Help description contains examples of how to use the micromapST function. Contained in this package are border group datasets to support creating linked micromap plots for the 50 U.S. states and District of Columbia (51 areas), the U. S. 20 Seer Registries, the 105 counties in the state of Kansas, the 62 counties of New York, the 24 counties of Maryland, the 29 counties of Utah, the 32 administrative areas in China, the 218 administrative areas in the UK and Ireland (for testing only), the 25 districts in the city of Seoul South Korea, and the 52 counties on the Africa continent. A border group dataset contains the boundaries related to the data level areas, a second layer boundaries, a top or third layer boundary, a parameter list of run options, and a cross indexing table between area names, abbreviations, numeric identification and alias matching strings for the specific geographic area. By specifying a border group, the package create linked micromap plots for any geographic region. The user can create and provide their own border group dataset for any area beyond the areas contained within the package with the BuildBorderGroup function. In April of 2022, it was announced that maptools', rgdal', and rgeos R packages would be retired in middle to end of 2023 and removed from the CRAN libraries. The BuildBorderGroup function was dependent on these packages. micromapST functions were not impacted by the retired R packages. Upgrading of BuildBorderGroup function was completed and released with version 3.0.0 on August 10, 2023 using the sf R package. References: Carr and Pickle, Chapman and Hall/CRC, Visualizing Data Patterns with Micromaps, CRC Press, 2010. Pickle, Pearson, and Carr (2015), micromapST: Exploring and Communicating Geospatial Patterns in US State Data., Journal of Statistical Software, 63(3), 1-25., <https://www.jstatsoft.org/v63/i03/>. Copyrighted 2013, 2014, 2015, 2016, 2022, 2023, 2024, and 2025 by Carr, Pearson and Pickle.

Machine coded genetic algorithm (MCGA) is a fast tool for real-valued optimization problems. It uses the byte representation of variables rather than real-values. It performs the classical crossover operations (uniform) on these byte representations. Mutation operator is also similar to classical mutation operator, which is to say, it changes a randomly selected byte value of a chromosome by +1 or -1 with probability 1/2. In MCGAs there is no need for encoding-decoding process and the classical operators are directly applicable on real-values. It is fast and can handle a wide range of a search space with high precision. Using a 256-unary alphabet is the main disadvantage of this algorithm but a moderate size population is convenient for many problems. Package also includes multi_mcga function for multi objective optimization problems. This function sorts the chromosomes using their ranks calculated from the non-dominated sorting algorithm.

Implementation of Matched Wake Analysis (mwa) for studying causal relationships in spatiotemporal event data, introduced by Schutte and Donnay (2014) <doi:10.1016/j.polgeo.2014.03.001>.

An ensemble meta-prediction framework to integrate multiple regression models into a current study. Gu, T., Taylor, J.M.G. and Mukherjee, B. (2020) <arXiv:2010.09971>. A meta-analysis framework along with two weighted estimators as the ensemble of empirical Bayes estimators, which combines the estimates from the different external models. The proposed framework is flexible and robust in the ways that (i) it is capable of incorporating external models that use a slightly different set of covariates; (ii) it is able to identify the most relevant external information and diminish the influence of information that is less compatible with the internal data; and (iii) it nicely balances the bias-variance trade-off while preserving the most efficiency gain. The proposed estimators are more efficient than the naive analysis of the internal data and other naive combinations of external estimators.

This package provides a set of functions, classes and methods for performing ABC and ABC/XYZ analyses, identifying overperforming, underperforming and constantly performing items, and plotting, analyzing as well as predicting the temporal development of items.

Epistasis, commonly defined as the interaction between genetic loci, is known to play an important role in the phenotypic variation of complex traits. As a result, many statistical methods have been developed to identify genetic variants that are involved in epistasis, and nearly all of these approaches carry out this task by focusing on analyzing one trait at a time. Previous studies have shown that jointly modeling multiple phenotypes can often dramatically increase statistical power for association mapping. In this package, we present the multivariate MArginal ePIstasis Test ('mvMAPIT') â a multi-outcome generalization of a recently proposed epistatic detection method which seeks to detect marginal epistasis or the combined pairwise interaction effects between a given variant and all other variants. By searching for marginal epistatic effects, one can identify genetic variants that are involved in epistasis without the need to identify the exact partners with which the variants interact â thus, potentially alleviating much of the statistical and computational burden associated with conventional explicit search based methods. Our proposed mvMAPIT builds upon this strategy by taking advantage of correlation structure between traits to improve the identification of variants involved in epistasis. We formulate mvMAPIT as a multivariate linear mixed model and develop a multi-trait variance component estimation algorithm for efficient parameter inference and P-value computation. Together with reasonable model approximations, our proposed approach is scalable to moderately sized genome-wide association studies. Crawford et al. (2017) <doi:10.1371/journal.pgen.1006869>. Stamp et al. (2023) <doi:10.1093/g3journal/jkad118>. Stamp et al. (2025) <doi:10.1016/j.ajhg.2025.07.004>.

It is a hybrid spatial model that combines the strength of two widely used regression models, MARS (Multivariate Adaptive Regression Splines) and GWR (Geographically Weighted Regression) to provide an effective approach for predicting a response variable at unknown locations. The MARS model is used in the first step of the development of a hybrid model to identify the most important predictor variables that assist in predicting the response variable. For method details see, Friedman, J.H. (1991). <DOI:10.1214/aos/1176347963>.The GWR model is then used to predict the response variable at testing locations based on these selected variables that account for spatial variations in the relationships between the variables. This hybrid model can improve the accuracy of the predictions compared to using an individual model alone.This developed hybrid spatial model can be useful particularly in cases where the relationship between the response variable and predictor variables is complex and non-linear, and varies across locations.