This package provides a suite of methods for powerful and robust microbiome data analysis, including data normalization, data simulation, community-level association testing and differential abundance analysis. It implements generalized UniFrac distances, Geometric Mean of Pairwise Ratios (GMPR) normalization, semiparametric data simulator, distance-based statistical methods, and feature- based statistical methods. The distance-based statistical methods include three extensions of PERMANOVA:

• PERMANOVA using the Freedman-Lane permutation scheme,

• PERMANOVA omnibus test using multiple matrices, and

• analytical approach to approximating PERMANOVA p-value.

Feature-based statistical methods include linear model-based methods for differential abundance analysis of zero-inflated high-dimensional compositional data.

This package loads electrophysiology data from ABF2 files, as created by Axon Instruments/Molecular Devices software. Only files recorded in gap-free mode are currently supported.

This is a package to read raw accelerometry from GT3X+ accelerometry data and plain table data to calculate the Activity Index from Bai et al. (2016) doi:10.1371/journal.pone.0160644.

This package performs prediction of a response function from simulated response values, allowing black-box optimization of functions estimated with some error. It includes a simple user interface for such applications, as well as more specialized functions designed to be called by the Migraine software (Rousset and Leblois, 2012 <doi:10.1093/molbev/MSR262>; Leblois et al., 2014 <doi:10.1093/molbev/msu212>; and see URL). The latter functions are used for prediction of likelihood surfaces and implied likelihood ratio confidence intervals, and for exploration of predictor space of the surface. Prediction of the response is based on ordinary Kriging (with residual error) of the input. Estimation of smoothing parameters is performed by generalized cross-validation.

This package provides a collection of fast (utility) functions for data analysis. Column- and row- wise means, medians, variances, minimums, maximums, many t, F and G-square tests, many regressions (normal, logistic, Poisson), are some of the many fast functions.

This package contains some functions to help users (especially data explorers) to make more sense of their variables and take the most out of variables and hardware resources. Functions in this package are supposed to be efficient and easy to use.

This package guesses the MIME type from a filename extension using the data derived from /etc/mime.types in UNIX-type systems.

This package provides an R interface to the nanoarrow C library and the Apache Arrow application binary interface. Functions to import and export ArrowArray, ArrowSchema, and ArrowArrayStream C structures to and from R objects are provided alongside helpers to facilitate zero-copy data transfer among R bindings to libraries implementing the Arrow C data interface.

This package provides an implementation of scale functions for setting axis breaks of a ggplot.

This package is a usability wrapper around snow for easier development of parallel R programs. This package offers e.g. extended error checks, and additional functions. All functions work in sequential mode, too, if no cluster is present or wished. The package is also designed as connector to the cluster management tool sfCluster, but can also used without it.

This is an extension to Shiny that brings interactions and animation effects from the jQuery UI library.

This package provides building blocks for the design and analysis of multiobjective optimization algorithms.

This package provides procedures to create preliminary exploratory data visualisations of an entire dataset to identify problems or unexpected features using ggplot2.

dplyr is the next iteration of plyr. It is focused on tools for working with data frames. It has three main goals: 1) identify the most important data manipulation tools needed for data analysis and make them easy to use in R; 2) provide fast performance for in-memory data by writing key pieces of code in C++; 3) use the same code interface to work with data no matter where it is stored, whether in a data frame, a data table or database.

This package provides functions and an RStudio add-in that search a BibTeX or BibLaTeX file to create and insert formatted Markdown citations into the current document.

Contains functions for data preparation, descriptives, hazard estimation and prediction with Aalen-Johansen or simulation in competing risks and multi-state models.

This package provides interpretability methods to analyze the behavior and predictions of any machine learning model. Implemented methods are:

• Feature importance described by Fisher et al. (2018),

• accumulated local effects plots described by Apley (2018),

• partial dependence plots described by Friedman (2001),

• individual conditional expectation ('ice') plots described by Goldstein et al. (2013) https://doi.org/10.1080/10618600.2014.907095,

• local models (variant of 'lime') described by Ribeiro et. al (2016),

• the Shapley Value described by Strumbelj et. al (2014) https://doi.org/10.1007/s10115-013-0679-x,

• feature interactions described by Friedman et. al https://doi.org/10.1214/07-AOAS148 and tree surrogate models.

This is a package for curve, surface and function fitting with an emphasis on splines, spatial data and spatial statistics. The major methods include cubic, and thin plate splines, Kriging, and compactly supported covariance functions for large data sets.

This package provides an implementation of scatter plots for plotting. a three dimensional point cloud.

This package computes model II simple linear regression using ordinary least squares (OLS), major axis (MA), standard major axis (SMA), and ranged major axis (RMA).

This package provides an extensible framework for the efficient calculation of auto- and cross-proximities, along with implementations of the most popular ones.

Plyr is a set of tools that solves a common set of problems: you need to break a big problem down into manageable pieces, operate on each piece and then put all the pieces back together. For example, you might want to fit a model to each spatial location or time point in your study, summarise data by panels or collapse high-dimensional arrays to simpler summary statistics.

This package lets you determine the significance of pre-defined sets of genes with respect to an outcome variable, such as a group indicator, a quantitative variable or a survival time.

This package provides beanplots, an alternative to boxplot/stripchart/violin plots. It can be used to plot univariate comparison graphs.