This package provides a basic set of R functions for querying the Cancer Genomics Data Server (CGDS), hosted by the Computational Biology Center at Memorial-Sloan-Kettering Cancer Center (MSKCC).

This package provides density, distribution, quantile and hazard functions of a stable variate, as well as generalized regression models for the parameters of a stable distribution.

This package contains data which are used by functions of the abc package which implements several Approximate Bayesian Computation (ABC) algorithms for performing parameter estimation, model selection, and goodness-of-fit.

This is a package to infer transmission trees from a dated phylogeny. It includes methods to simulate and analyze outbreaks. The methodology is described in Didelot et al. (2014) and Didelot et al. (2017).

This package converts back and forth between two representations of a convex polytope: as solution of a set of linear equalities and inequalities and as convex hull of set of points and rays. Also does linear programming and redundant generator elimination. All functions can use exact infinite-precision rational arithmetic.

This package provides a suite of custom R Markdown formats and templates for authoring journal articles and conference submissions.

This package lets you interact with Google Sheets through the Sheets API v4. This package can read and write both the metadata and the cell data in a Sheet.

This package provides a simple and intuitive pipe-friendly framework, coherent with the tidyverse design philosophy, for performing basic statistical tests, including t-test, Wilcoxon test, ANOVA, Kruskal-Wallis and correlation analyses. The output of each test is automatically transformed into a tidy data frame to facilitate visualization. Additional functions are available for reshaping, reordering, manipulating and visualizing correlation matrix.

This package provides tools to compute ordinal, statistics and effect sizes as an alternative to mean comparison: Cliff's delta or success rate difference (SRD), Vargha and Delaney's A or the Area Under a Receiver Operating Characteristic Curve (AUC), the discrete type of McGraw & Wong's Common Language Effect Size (CLES) or Grissom & Kim's Probability of Superiority (PS), and the Number needed to treat (NNT) effect size. Moreover, comparisons to Cohen's d are offered based on Huberty & Lowman's Percentage of Group (Non-)Overlap considerations.

Regression methods to quantify the relation between two measurement methods are provided by this package. In particular it addresses regression problems with errors in both variables and without repeated measurements. It implements the CLSI recommendations (see J. A. Budd et al. (2018, https://clsi.org/standards/products/method-evaluation/documents/ep09/) for analytical method comparison and bias estimation using patient samples. Furthermore, algorithms for Theil-Sen and equivariant Passing-Bablok estimators are implemented, see F. Dufey (2020, <doi:10.1515/ijb-2019-0157>) and J. Raymaekers and F. Dufey (2022, <arXiv:2202:08060>). A comprehensive overview over the implemented methods and references can be found in the manual pages mcr-package and mcreg.

This package provides meta-analysis methods that correct for publication bias and outcome reporting bias. Four methods and a visual tool are currently included in the package.

1. The p-uniform method as described in van Assen, van Aert, and Wicherts (2015) doi:10.1037/met0000025 can be used for estimating the average effect size, testing the null hypothesis of no effect, and testing for publication bias using only the statistically significant effect sizes of primary studies.

2. The p-uniform* method as described in van Aert and van Assen (2019) doi:10.31222/osf.io/zqjr9. This method is an extension of the p-uniform method that allows for estimation of the average effect size and the between-study variance in a meta-analysis, and uses both the statistically significant and nonsignificant effect sizes.

3. The hybrid method as described in van Aert and van Assen (2017) doi:10.3758/s13428-017-0967-6. The hybrid method is a meta-analysis method for combining an original study and replication and while taking into account statistical significance of the original study. The p-uniform and hybrid method are based on the statistical theory that the distribution of p-values is uniform conditional on the population effect size.

4. The fourth method in the package is the Snapshot Bayesian Hybrid Meta-Analysis Method as described in van Aert and van Assen (2018) doi:10.1371/journal.pone.0175302. This method computes posterior probabilities for four true effect sizes (no, small, medium, and large) based on an original study and replication while taking into account publication bias in the original study. The method can also be used for computing the required sample size of the replication akin to power analysis in null hypothesis significance testing.

The meta-plot is a visual tool for meta-analysis that provides information on the primary studies in the meta-analysis, the results of the meta-analysis, and characteristics of the research on the effect under study (van Assen and others, 2020).

Helper functions to apply the Correcting for Outcome Reporting Bias (CORB) method to correct for outcome reporting bias in a meta-analysis (van Aert & Wicherts, 2020).

This package provides alternative statistical methods for meta-analysis, including:

1. bivariate generalized linear mixed models for synthesizing odds ratios, relative risks, and risk differences

2. heterogeneity tests and measures that are robust to outliers;

3. measures, tests, and visualization tools for publication bias or small-study effects;

4. meta-analysis of diagnostic tests for synthesizing sensitivities, specificities, etc.;

5. meta-analysis methods for synthesizing proportions;

6. models for multivariate meta-analysis.

This package provides a syntax highlighter for R code based on the results of the R parser. It supports rendering in HTML and LaTeX markup. It includes a custom Sweave driver performing syntax highlighting of R code chunks.

This package provides a Wrapper around the SVDLIBC library for (truncated) singular value decomposition of a sparse matrix. Currently, only sparse real matrices in Matrix package format are supported.

This package provides means to run simulations for adaptive seamless designs with and without early outcomes for treatment selection and subpopulation type designs.

This package provides alluvial plots for ggplot2. Alluvial plots use variable-width ribbons and stacked bar plots to represent multi-dimensional or repeated-measures data with categorical or ordinal variables.

The ps package implements an API to list, query, and manipulate system processes. Most of its code is based on the psutil Python package.

The GNU Scientific Library (or GSL) is a collection of numerical routines for scientific computing. It is particularly useful for C and C++ programs as it provides a standard C interface to a wide range of mathematical routines. There are over 1000 functions in total with an extensive test suite. The RcppGSL package provides an easy-to-use interface between GSL data structures and R using concepts from Rcpp which is itself a package that eases the interfaces between R and C++.

Create interactive ggplot2 graphics using htmlwidgets.

This package provides simple and secure authentication mechanism for single Shiny applications. Credentials are stored in an encrypted SQLite database.

This package provides a set of functions with example data for graphing, pruning, and mapping models. These models are from hierarchical clustering, and classification and regression trees.

This package provides tools for stochastic fractal and deterministic chaotic time series analysis.

This package provides various themes, palettes, and other functions that are used to customise ggplots to look like they were made in GraphPad Prism. The Prism-look is achieved with theme_prism() and scale_fill|colour_prism(), axes can be changed with custom guides like guide_prism_minor(), and significance indicators added with add_pvalue().

This package lets you construct paths to your project's files. Use the here function as a drop-in replacement for file.path, it will always locate the files relative to your project root.