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This method identifies topological domains in genomes from Hi-C sequence data. The authors published an implementation of their method as an R script. This package originates from those original TopDom R scripts and provides help pages adopted from the original TopDom PDF documentation. It also provides a small number of bug fixes to the original code.
This package contains:
facilities for working with grouped data:
dosomething to data stratifiedbysome variables.implementations of least-squares means, general linear contrasts, and
miscellaneous other utilities.
This is a package for slanted matrices and ordered clustering for better visualization of similarity data.
This package provides tools to fit and compare Ornstein-Uhlenbeck models for evolution along a phylogenetic tree.
Lambert W x F distributions are a generalized framework to analyze skewed, heavy-tailed data. It is based on an input/output system, where the output random variable (RV) Y is a non-linearly transformed version of an input RV X ~ F with similar properties as X, but slightly skewed (heavy-tailed). The transformed RV Y has a Lambert W x F distribution. This package contains functions to model and analyze skewed, heavy-tailed data the Lambert Way: simulate random samples, estimate parameters, compute quantiles, and plot/ print results nicely. The most useful function is Gaussianize, which works similarly to scale, but actually makes the data Gaussian. A do-it-yourself toolkit allows users to define their own Lambert W x MyFavoriteDistribution and use it in their analysis right away.
This package provides an R interface to the vis.js JavaScript charting library. It allows an interactive visualization of networks.
This package provides a mutation analysis tool that discovers cancer driver genes with frequent mutations in protein signalling sites such as post-translational modifications (phosphorylation, ubiquitination, etc). The Poisson generalized linear regression model identifies genes where cancer mutations in signalling sites are more frequent than expected from the sequence of the entire gene. Integration of mutations with signalling information helps find new driver genes and propose candidate mechanisms to known drivers.
Ggfittext is a ggplot2 extension for fitting text into boxes.
This package provides an R-based solution for symbolic differentiation. It admits user-defined functions as well as function substitution in arguments of functions to be differentiated. Some symbolic simplification is part of the work.
The aim of SHAPforxgboost is to aid in visual data investigations using SHAP (Shapley additive explanation) visualization plots for XGBoost. It provides summary plot, dependence plot, interaction plot, and force plot. It relies on the XGBoost package to produce SHAP values.
This package provides software and data for the book "An Introduction to the Bootstrap" by B. Efron and R. Tibshirani, 1993, Chapman and Hall. This package is primarily provided for projects already based on it, and for support of the book. New projects should preferentially use the recommended package "boot".
Kernel factory is an ensemble method where each base classifier (random forest) is fit on the kernel matrix of a subset of the training data.
Full 64-bit resolution date and time functionality with nanosecond granularity is provided, with easy transition to and from the standard POSIXct type. Three additional classes offer interval, period and duration functionality for nanosecond-resolution timestamps.
This package provides functionality to benchmark your CPU and compare against other CPUs. Also provides functions for obtaining system specifications, such as RAM, CPU type, and R version.
This package provides tools to compute ordinal, statistics and effect sizes as an alternative to mean comparison: Cliff's delta or success rate difference (SRD), Vargha and Delaney's A or the Area Under a Receiver Operating Characteristic Curve (AUC), the discrete type of McGraw & Wong's Common Language Effect Size (CLES) or Grissom & Kim's Probability of Superiority (PS), and the Number needed to treat (NNT) effect size. Moreover, comparisons to Cohen's d are offered based on Huberty & Lowman's Percentage of Group (Non-)Overlap considerations.
The vegan package provides tools for descriptive community ecology. It has most basic functions of diversity analysis, community ordination and dissimilarity analysis. Most of its multivariate tools can be used for other data types as well.
Postprocessors refine predictions outputted from machine learning models to improve predictive performance or better satisfy distributional limitations. This package introduces tailor objects, which compose iterative adjustments to model predictions. A number of pre-written adjustments are provided with the package, such as calibration. See Lichtenstein, Fischhoff, and Phillips (1977) <doi:10.1007/978-94-010-1276-8_19>. Other methods and utilities to compose new adjustments are also included. Tailors are tightly integrated with the tidymodels framework.
This package provides tools for HTML generation and output in R.
This is a package for pretty-printing R code without changing the user's formatting intent.
This package provides auxiliary functions and data sets for "Ecological Models and Data", a book presenting maximum likelihood estimation and related topics for ecologists (ISBN 978-0-691-12522-0).
This is a package for maximum likelihood estimation of random utility discrete choice models. The software is described in Croissant (2020) <doi:10.18637/jss.v095.i11> and the underlying methods in Train (2009) <doi:10.1017/CBO9780511805271>.
This package provides data sets and scripts to accompany Time Series Analysis and Its Applications: With R Examples (4th ed), by R.H. Shumway and D.S. Stoffer. Springer Texts in Statistics, 2017, https://doi.org/10.1007/978-3-319-52452-8, and Time Series: A Data Analysis Approach Using R. Chapman-Hall, 2019, https://doi.org/10.1201/9780429273285.
R-tgb provides Bayesian nonstationary regression and treed Gaussian processes. In addition, it provides visualization functions, tree drawing, sensitivity analysis, multi-resolution models, and sequential experimental design tools, including ALM, ALC, and expected improvement for optimizing noisy black-box functions.
Flexible general-purpose toolbox implementing genetic algorithms (GAs) for stochastic optimisation. Binary, real-valued, and permutation representations are available to optimize a fitness function, i.e., a function provided by users depending on their objective function. Several genetic operators are available and can be combined to explore the best settings for the current task. Furthermore, users can define new genetic operators and easily evaluate their performances. Local search using general-purpose optimisation algorithms can be applied stochastically to exploit interesting regions. GAs can be run sequentially or in parallel, using an explicit master-slave parallelisation or a coarse-grain islands approach.