This package provides a non-linear model, termed ACME, that reflects a parsimonious biological model for allelic contributions of cis-acting eQTLs. With non-linear least-squares algorithm the maximum likelihood parameters can be estimated. The ACME model provides interpretable effect size estimates and p-values with well controlled Type-I error.

This package provides tools to fit Rasch models (RM), linear logistic test models (LLTM), rating scale model (RSM), linear rating scale models (LRSM), partial credit models (PCM), and linear partial credit models (LPCM). Missing values are allowed in the data matrix. Additional features are the ML estimation of the person parameters, Andersen's LR-test, item-specific Wald test, Martin-Loef-Test, nonparametric Monte-Carlo Tests, itemfit and personfit statistics including infit and outfit measures, ICC and other plots, automated stepwise item elimination, and a simulation module for various binary data matrices.

This package provides a C++ header library for using the libsoda-cxx library with R. The C++ header reimplements the lsoda function from the ODEPACK library for solving initial value problems for first order ordinary differential equations. The C++ header can be used by other R packages by linking against this package. The C++ functions can be called inline using Rcpp. Finally, the package provides an ode function to call from R.

The generalised lambda distribution, or Tukey lambda distribution, provides a wide variety of shapes with one functional form. This package provides random numbers, quantiles, probabilities, densities and density quantiles for four different types of the distribution, the FKML (Freimer et al 1988), RS (Ramberg and Schmeiser 1974), GPD (van Staden and Loots 2009) and FM5 - see documentation for details. It provides the density function, distribution function, and Quantile-Quantile plots. It implements a variety of estimation methods for the distribution, including diagnostic plots. Estimation methods include the starship (all 4 types), method of L-Moments for the GPD and FKML types, and a number of methods for only the FKML type. These include maximum likelihood, maximum product of spacings, Titterington's method, Moments, Trimmed L-Moments and Distributional Least Absolutes.

Cluster ensembles are collections of individual solutions to a given clustering problem which are useful or necessary to consider in a wide range of applications. This R package provides an extensible computational environment for creating and analyzing cluster ensembles, with basic data structures for representing partitions and hierarchies, and facilities for computing on them, including methods for measuring proximity and obtaining consensus and secondary clusterings.

This package provides various R programming tools for data manipulation, including:

• medical unit conversions

• combining objects

• character vector operations

• factor manipulation

• obtaining information about R objects

• generating fixed-width format files

• extricating components of date and time objects

• operations on columns of data frames

• matrix operations

• operations on vectors and data frames

• value of last evaluated expression

• wrapper for sample that ensures consistent behavior for both scalar and vector arguments

This package provides a unified pipeline to clean, prepare, plot, and run basic analyses on pupillometry experiments.

This package lets you replace the standard x-axis in ggplots with a combination matrix to visualize complex set overlaps. UpSet has introduced a new way to visualize the overlap of sets as an alternative to Venn diagrams. This package provides a simple way to produce such plots using ggplot2. In addition it can convert any categorical axis into a combination matrix axis.

This package provides the dyn class interfaces ts, irts, zoo and zooreg time series classes to lm, glm, loess, quantreg::rq, MASS::rlm, MCMCpack::MCMCregress(), quantreg::rq(), randomForest::randomForest() and other regression functions, allowing those functions to be used with time series including specifications that may contain lags, diffs and missing values.

This package provides various methods for MRI tissue classification.

This package uses both ridge and lasso penalties (and extensions) to penalize specific parameters in structural equation models. The package offers additional cost functions, cross validation, and other extensions beyond traditional structural equation models. It also contains a function to perform exploratory mediation (XMed).

This package provides a Davidian curve defines a seminonparametric density, whose shape and flexibility can be tuned by easy to estimate parameters. Since a special case of a Davidian curve is the standard normal density, Davidian curves can be used for relaxing normality assumption in statistical applications (Zhang & Davidian, 2001) <doi:10.1111/j.0006-341X.2001.00795.x>. This package provides the density function, the gradient of the loglikelihood and a random generator for Davidian curves.

This package provides tools for data importation, recoding, and inspection. There are functions to create new project folders, R code templates, create uniquely named output directories, and to quickly obtain a visual summary for each variable in a data frame. The main feature here is the systematic implementation of the "variable key" framework for data importation and recoding.

This package provides a graphical display of a correlation matrix or general matrix. It also contains some algorithms to do matrix reordering. In addition, corrplot is good at details, including choosing color, text labels, color labels, layout, etc.

This package provides an interface to Amazon Web Services cost management services, including cost and usage reports, budgets, pricing, and more.

This is an R package for imputing dropout events. Many statistical methods in cell type identification, visualization and lineage reconstruction do not account for dropout events. DrImpute can improve the performance of such software by imputing dropout events.

This package provides several analysis-related functions for the book entitled "R statistics and graph for medical articles" (written in Korean), version 1, by Keon-Woong Moon with Korean demographic data with several plot functions.

This package provides a set of simple functions that transforms longitudinal data to estimate the cosinor linear model as described in Tong (1976). Methods are given to summarize the mean, amplitude and acrophase, to predict the mean annual outcome value, and to test the coefficients.

This is an extension to Shiny that brings interactions and animation effects from the jQuery UI library.

This package provides functions for making low-level API requests to Amazon Web Services. The functions handle building, signing, and sending requests, and receiving responses. They are designed to help build higher-level interfaces to individual services, such as Simple Storage Service (S3).

This package provides functions for analysing, manipulating, displaying, editing and synthesizing time waves (particularly sound). This package processes time analysis (oscillograms and envelopes), spectral content, resonance quality factor, entropy, cross correlation and autocorrelation, zero-crossing, dominant frequency, analytic signal, frequency coherence, 2D and 3D spectrograms and many other analyses.

This package lets you create a web app that makes it easier to test web clients without using the internet. It includes a web app framework with path matching, parameters and templates. It can parse various HTTP request bodies. It can send JSON data or files from the disk. It includes a web app that implements the httpbin.org web service.

This package computes cell fate bias for multi-lineage single-cell data. It also provides visualization tools for analyzing these biases.

This started out as a package for file and string manipulation. Since then, the fs and strex packages emerged, offering functionality previously given by this package. Those packages have hence almost pushed filesstrings into extinction. However, it still has a small number of unique, handy file manipulation functions which can be seen in the vignette. One example is a function to remove spaces from all file names in a directory.