This package provides tools for testing, monitoring and dating structural changes in (linear) regression models. It features tests/methods from the generalized fluctuation test framework as well as from the F test (Chow test) framework. This includes methods to fit, plot and test fluctuation processes (e.g., CUSUM, MOSUM, recursive/moving estimates) and F statistics, respectively. It is possible to monitor incoming data online using fluctuation processes. Finally, the breakpoints in regression models with structural changes can be estimated together with confidence intervals. Emphasis is always given to methods for visualizing the data.

This package provides a collection of perceptually uniform color maps made by Peter Kovesi (2015) "Good Colour Maps: How to Design Them" <arXiv:1509.03700> at the Centre for Exploration Targeting (CET).

This package provides tools for exploratory data analysis and data visualization of biological sequence (DNA and protein) data. It also includes utilities for sequence data management under the ACNUC system.

This package provides a fast dimensionality reduction method scalable to large numbers of samples. Landmark Multi-Dimensional Scaling (LMDS) is an extension of classical Torgerson MDS, but rather than calculating a complete distance matrix between all pairs of samples, only the distances between a set of landmarks and the samples are calculated.

The package includes the necessary functions to construct a self-organizing map of data, to evaluate the statistical significance of the observed data patterns, and to visualize the results.

This package provides utilities for computation and analysis of correlation/covariation in multiple sequence alignments and in side chain motions during molecular dynamics simulations. Features include the computation of correlation/covariation scores using a variety of scoring functions between either sequence positions in alignments or side chain dihedral angles in molecular dynamics simulations and utilities to analyze the correlation/covariation matrix through a variety of tools including network representation and principal components analysis. In addition, several utility functions are based on the R graphical environment to provide friendly tools for help in data interpretation.

Deciding what resolution to use can be a difficult question when approaching a clustering analysis. One way to approach this problem is to look at how samples move as the number of clusters increases. This package allows you to produce clustering trees, a visualization for interrogating clusterings as resolution increases.

This package provides a set of R functions for identifying and correcting HGNC human gene symbols. In addition, you can identify MGI mouse gene symbols, which have been converted to date format by Excel, withdrawn, or aliased. It also contains functions for reversibly converting between HGNC symbols and valid R names.

This package provides tools to generate a violin point plot, a combination of a violin/histogram plot and a scatter plot by offsetting points within a category based on their density using quasirandom noise.

This package provides alternative statistical methods for meta-analysis, including:

1. bivariate generalized linear mixed models for synthesizing odds ratios, relative risks, and risk differences

2. heterogeneity tests and measures that are robust to outliers;

3. measures, tests, and visualization tools for publication bias or small-study effects;

4. meta-analysis of diagnostic tests for synthesizing sensitivities, specificities, etc.;

5. meta-analysis methods for synthesizing proportions;

6. models for multivariate meta-analysis.

Extract metadata from NetCDF data sources; these can be files, file handles or servers. This package leverages and extends the lower level functions of the RNetCDF package providing a consistent set of functions that all return data frames.

This package provides Cramer-Von Mises and Anderson-Darling tests of goodness-of-fit for continuous univariate distributions, using efficient algorithms.

Create and manage unique directories for each TensorFlow training run. This package provides a unique, time stamped directory for each run along with functions to retrieve the directory of the latest run or latest several runs.

When testing multiple hypotheses simultaneously, this package provides functionality to calculate a lower bound for the number of correct rejections (as a function of the number of rejected hypotheses), which holds simultaneously -with high probability- for all possible number of rejections. As a special case, a lower bound for the total number of false null hypotheses can be inferred. Dependent test statistics can be handled for multiple tests of associations. For independent test statistics, it is sufficient to provide a list of p-values.

This package aims to provide the most useful subset of Boost libraries for template use among CRAN packages.

This package offers an implementation of the Abnormal blood profile score (ABPS). The ABPS is a part of the Athlete biological passport program of the World anti-doping agency, which combines several blood parameters into a single score in order to detect blood doping. The package also contains functions to calculate other scores used in anti-doping programs, such as the ratio of hemoglobin to reticulocytes (OFF-score), as well as example data.

This package provides a series of shortcuts for routine tasks to facilitate data exploration.

This package provides code analysis tools for R to check R code for possible problems.

Finding an optimal Bayesian experimental design involves maximizing an objective function given by the expectation of some appropriately chosen utility function with respect to the joint distribution of unknown quantities (including responses). This objective function is usually not available in closed form and the design space can be continuous and of high dimensionality. This package uses Approximate Coordinate Exchange (ACE) to maximise an approximation to the expectation of the utility function.

Regression methods to quantify the relation between two measurement methods are provided by this package. In particular it addresses regression problems with errors in both variables and without repeated measurements. It implements the CLSI recommendations (see J. A. Budd et al. (2018, https://clsi.org/standards/products/method-evaluation/documents/ep09/) for analytical method comparison and bias estimation using patient samples. Furthermore, algorithms for Theil-Sen and equivariant Passing-Bablok estimators are implemented, see F. Dufey (2020, <doi:10.1515/ijb-2019-0157>) and J. Raymaekers and F. Dufey (2022, <arXiv:2202:08060>). A comprehensive overview over the implemented methods and references can be found in the manual pages mcr-package and mcreg.

This package is an R package designed for QC, analysis, and exploration of single cell RNA-seq data. It easily enables widely-used analytical techniques, including the identification of highly variable genes, dimensionality reduction; PCA, ICA, t-SNE, standard unsupervised clustering algorithms; density clustering, hierarchical clustering, k-means, and the discovery of differentially expressed genes and markers.

This package provides a toolkit of functions for nonlinear regression and repeated measurements. It was designated to be imported by other packages such as gnlm, stable, growth, repeated, and event.

This package provides functions, documentation and example data to help divide geographic space into discrete polygons (zones). The functions are motivated by research into the merits of different zoning systems. A flexible ClockBoard zoning system is provided, which breaks-up space by concentric rings and radial lines emanating from a central point.

This package extends the fitdistr function of the MASS package with several functions to help the fit of a parametric distribution to non-censored or censored data. Censored data may contain left-censored, right-censored and interval-censored values, with several lower and upper bounds. In addition to maximum likelihood estimation (MLE), the package provides moment matching (MME), quantile matching (QME) and maximum goodness-of-fit estimation (MGE) methods (available only for non-censored data). Weighted versions of MLE, MME and QME are available.