This package provides a native R plotting library that provides a flexible declarative interface for creating interactive web-based graphics, backed by the Bokeh visualization library.

This package allows for fast, correct, consistent, portable, as well as convenient character string/text processing in every locale and any native encoding. Owing to the use of the ICU library, the package provides R users with platform-independent functions known to Java, Perl, Python, PHP, and Ruby programmers. Among available features there are: pattern searching (e.g. via regular expressions), random string generation, string collation, transliteration, concatenation, date-time formatting and parsing, etc.

Lp_solve is software for solving linear, integer and mixed integer programs. This implementation supplies a "wrapper" function in C and some R functions that solve general linear/integer problems, assignment problems, and transportation problems.

Zero-variance control variates (ZV-CV) is a post-processing method to reduce the variance of Monte Carlo estimators of expectations using the derivatives of the log target. Once the derivatives are available, the only additional computational effort is in solving a linear regression problem. This method has been extended to higher dimensions using regularisation. This package can be used to easily perform ZV-CV or regularised ZV-CV when a set of samples, derivatives and function evaluations are available. Additional functions for applying ZV-CV to two estimators for the normalising constant of the posterior distribution in Bayesian statistics are also supplied.

The h5Seurat file format is specifically designed for the storage and analysis of multi-modal single-cell and spatially-resolved expression experiments, for example, from CITE-seq or 10X Visium technologies. It holds all molecular information and associated metadata, including (for example) nearest-neighbor graphs, dimensional reduction information, spatial coordinates and image data, and cluster labels. This package also supports rapid and on-disk conversion between h5Seurat and AnnData objects, with the goal of enhancing interoperability between Seurat and Scanpy.

This package contains:

• facilities for working with grouped data: do something to data stratified by some variables.

• implementations of least-squares means, general linear contrasts, and

• miscellaneous other utilities.

This package provides functions for making low-level API requests to Amazon Web Services. The functions handle building, signing, and sending requests, and receiving responses. They are designed to help build higher-level interfaces to individual services, such as Simple Storage Service (S3).

This package provides tools for determining estimability of linear functions of regression coefficients, and epredict methods that handle non-estimable cases correctly.

Analyze count time series with excess zeros. Two types of statistical models are supported: Markov regression and state-space models. They are also known as observation-driven and parameter-driven models respectively in the time series literature. The functions used for Markov regression or observation-driven models can also be used to fit ordinary regression models with independent data under the zero-inflated Poisson (ZIP) or zero-inflated negative binomial (ZINB) assumption. The package also contains miscellaneous functions to compute density, distribution, quantile, and generate random numbers from ZIP and ZINB distributions.

This package is a collection of miscellaneous utility functions, supporting data transformation tasks like recoding, dichotomizing or grouping variables, setting and replacing missing values. The data transformation functions also support labelled data, and all integrate seamlessly into a tidyverse workflow.

The SciViews svGUI package eases the management of Graphical User Interfaces (GUI) in R. It is independent from any particular GUI widgets. It centralizes info about GUI elements currently used, and it dispatches GUI calls to the particular toolkits in use in function of the context.

This package provides infrastructure for seriation with an implementation of several seriation/sequencing techniques to reorder matrices, dissimilarity matrices, and dendrograms. It also provides (optimally) reordered heatmaps, color images and clustering visualizations like dissimilarity plots, and visual assessment of cluster tendency plots (VAT and iVAT).

Feature Selection with Regularized Random Forest. This package is based on the randomForest package by Andy Liaw. The key difference is the RRF() function that builds a regularized random forest. Fortran original by Leo Breiman and Adele Cutler, R port by Andy Liaw and Matthew Wiener, Regularized random forest for classification by Houtao Deng, Regularized random forest for regression by Xin Guan. Reference: Houtao Deng (2013) <doi:10.48550/arXiv.1306.0237>.

This package provides a cross-platform command-line argument parser written purely in R with no external dependencies. It is useful with the Rscript front-end and facilitates turning an R script into an executable script.

Bivariate data interpolation on regular and irregular grids, either linear or using splines are the main part of this package. It is intended to provide replacement functions for the ACM licensed akima::interp and tripack::tri.mesh functions.

This package represents an implementation of functions to optimize ordering of nodes in a dendrogram, without affecting the meaning of the dendrogram. A dendrogram can be sorted based on the average distance of subtrees, or based on the smallest distance value. These sorting methods improve readability and interpretability of tree structure, especially for tasks such as comparison of different distance measures or linkage types and identification of tight clusters and outliers. As a result, it also introduces more meaningful reordering for a coupled heatmap visualization.

This is a package for the manipulation of genetic data (SNPs). Computation of genetic relationship matrix (GRM) and dominance matrix, linkage disequilibrium (LD), and heritability with efficient algorithms for linear mixed models (AIREML).

This package provides various methods for clustering and cluster validation. For example, it provides fixed point clustering, linear regression clustering, clustering by merging Gaussian mixture components, as well as symmetric and asymmetric discriminant projections for visualisation of the separation of groupings.

This package provides an R wrapper for libnabo, an exact or approximate k nearest neighbour library which is optimised for low dimensional spaces (e.g. 3D). nabor includes a knn function that is designed as a drop-in replacement for the RANN function nn2. In addition, objects which include the k-d tree search structure can be returned to speed up repeated queries of the same set of target points.

This package provides tools for pretty, human readable formatting of quantities.

This package lets you edit and simplify geojson, Spatial, and sf objects. This is a wrapper around the mapshaper JavaScript library to perform topologically-aware polygon simplification, as well as other operations such as clipping, erasing, dissolving, and converting multi-part to single-part geometries.

This package provides several cluster-robust variance estimators (i.e., sandwich estimators) for ordinary and weighted least squares linear regression models, including the bias-reduced linearization estimator introduced by Bell and McCaffrey (2002) http://www.statcan.gc.ca/pub/12-001-x/2002002/article/9058-eng.pdf and developed further by Pustejovsky and Tipton (2017) doi:10.1080/07350015.2016.1247004. The package includes functions for estimating the variance- covariance matrix and for testing single- and multiple-contrast hypotheses based on Wald test statistics. Tests of single regression coefficients use Satterthwaite or saddle-point corrections. Tests of multiple-contrast hypotheses use an approximation to Hotelling's T-squared distribution. Methods are provided for a variety of fitted models, including lm() and mlm objects, glm(), ivreg (from package AER), plm() (from package plm), gls() and lme() (from nlme), robu() (from robumeta), and rma.uni() and rma.mv() (from metafor).

This package provides basic I/O tools for streaming and data parsing.

The r-abd package contains data sets and sample code for the Analysis of biological data by Michael Whitlock and Dolph Schluter.