Seek the significant cutoff value for a continuous variable, which will be transformed into a classification, for linear regression, logistic regression, logrank analysis and cox regression. First of all, all combinations will be gotten by combn() function. Then n.per argument, abbreviated of total number percentage, will be used to remove the combination of smaller data group. In logistic, Cox regression and logrank analysis, we will also use p.per argument, patient percentage, to filter the lower proportion of patients in each group. Finally, p value in regression results will be used to get the significant combinations and output relevant parameters. In this package, there is no limit to the number of cutoff points, which can be 1, 2, 3 or more. Still, we provide 2 methods, typical Bonferroni and Duglas G (1994) <doi: 10.1093/jnci/86.11.829>, to adjust the p value, Missing values will be deleted by na.omit() function before analysis.

This package implements a kernel-based association test for copy number variation (CNV) aggregate analysis in a certain genomic region (e.g., gene set, chromosome, or genome) that is robust to the within-locus and across-locus etiological heterogeneity, and bypass the need to define a "locus" unit for CNVs. Brucker, A., et al. (2020) <doi:10.1101/666875>.

CUR/CX decomposition factorizes a matrix into two factor matrices and Multidimensional CX Decomposition factorizes a tensor into a core tensor and some factor matrices. See the reference section of GitHub README.md <https://github.com/rikenbit/ccTensor>, for details of the methods.

Significance test of Spearman's Rho or Kendall's Tau between short-range dependent random variables.

It has been designed to calculate the required sample size in randomized clinical trials with composite endpoints. It also calculates the expected effect and the probability of observing the composite endpoint, among others. The methodology can be found in Bofill & Gómez (2019) <doi:10.1002/sim.8092> and Gómez & Lagakos (2013) <doi:10.1002/sim.5547>.

This package provides classes (S4) of commonly used elliptical, Archimedean, extreme-value and other copula families, as well as their rotations, mixtures and asymmetrizations. Nested Archimedean copulas, related tools and special functions. Methods for density, distribution, random number generation, bivariate dependence measures, Rosenblatt transform, Kendall distribution function, perspective and contour plots. Fitting of copula models with potentially partly fixed parameters, including standard errors. Serial independence tests, copula specification tests (independence, exchangeability, radial symmetry, extreme-value dependence, goodness-of-fit) and model selection based on cross-validation. Empirical copula, smoothed versions, and non-parametric estimators of the Pickands dependence function.

This package provides functions for calculating and evaluating likelihood ratios from uni/multivariate continuous observations.

Perform evaluation of automatic subject indexing methods. The main focus of the package is to enable efficient computation of set retrieval and ranked retrieval metrics across multiple dimensions of a dataset, e.g. document strata or subsets of the label set. The package also provides the possibility of computing bootstrap confidence intervals for all major metrics, with seamless integration of parallel computation and propensity scored variants of standard metrics.

The Chinese ID number contains a lot of information, this package helps you get the region, date of birth, age, age based on year, gender, zodiac, constellation information from the Chinese ID number.

Process Digital Cover Photography images of tree canopies to get canopy attributes like Foliage Cover and Leaf Area Index. Detailed description of the methods in Chianucci et al. (2022) <doi:10.1007/s00468-018-1666-3>.

Download and read data on United States congressional proceedings. Data is read from the Library of Congress's Congress.gov Application Programming Interface (<https://github.com/LibraryOfCongress/api.congress.gov/>). Functions exist for all version 3 endpoints, including for bills, amendments, congresses, summaries, members, reports, communications, nominations, and treaties.

This package implements Cragg-Donald (1993) <doi:10.1017/S0266466600007519> and Stock and Yogo (2005) <doi:10.1017/CBO9780511614491.006> tests for weak instruments in R.

Various tools for inferring causal models from observational data. The package includes an implementation of the temporal Peter-Clark (TPC) algorithm. Petersen, Osler and Ekstrøm (2021) <doi:10.1093/aje/kwab087>. It also includes general tools for evaluating differences in adjacency matrices, which can be used for evaluating performance of causal discovery procedures.

This package provides the "comma-free call" operator: %(%'. Use it to call a function without commas between the arguments. Just replace the ( with %(% in a function call, supply your arguments as standard R expressions enclosed by ', and be free of commas (for that call).

This package provides tools for interacting with the Circle CI API (<https://circleci.com/docs/api/v2/>). Besides executing common tasks such as querying build logs and restarting builds, this package also helps setting up permissions to deploy from builds.

Calculate date of birth, age, and gender, and generate anonymous sequence numbers from CPR numbers. <https://en.wikipedia.org/wiki/Personal_identification_number_(Denmark)>.

Multivariate random forests with compositional responses and Euclidean predictors is performed. The compositional data are first transformed using the additive log-ratio transformation, or the alpha-transformation of Tsagris, Preston and Wood (2011), <doi:10.48550/arXiv.1106.1451>, and then the multivariate random forest of Rahman R., Otridge J. and Pal R. (2017), <doi:10.1093/bioinformatics/btw765>, is applied.

Composite Kernel Machine Regression based on Likelihood Ratio Test (CKLRT): in this package, we develop a kernel machine regression framework to model the overall genetic effect of a SNP-set, considering the possible GE interaction. Specifically, we use a composite kernel to specify the overall genetic effect via a nonparametric function and we model additional covariates parametrically within the regression framework. The composite kernel is constructed as a weighted average of two kernels, one corresponding to the genetic main effect and one corresponding to the GE interaction effect. We propose a likelihood ratio test (LRT) and a restricted likelihood ratio test (RLRT) for statistical significance. We derive a Monte Carlo approach for the finite sample distributions of LRT and RLRT statistics. (N. Zhao, H. Zhang, J. Clark, A. Maity, M. Wu. Composite Kernel Machine Regression based on Likelihood Ratio Test with Application for Combined Genetic and Gene-environment Interaction Effect (Submitted).).

Estimates conditional binary quantile models developed by Lu (2020) <doi:10.1017/pan.2019.29>. The estimation procedure is implemented based on Markov chain Monte Carlo methods.

This package provides a matrix of agreement patterns and counts for record pairs is the input for the procedure. An EM algorithm is used to impute plausible values for missing record pairs. A second EM algorithm, incorporating possible correlations between per-field agreement, is used to estimate posterior probabilities that each pair is a true match - i.e. constitutes the same individual.

Computes a range of scatterplot diagnostics (scagnostics) on pairs of numerical variables in a data set. A range of scagnostics, including graph and association-based scagnostics described by Leland Wilkinson and Graham Wills (2008) <doi:10.1198/106186008X320465> and association-based scagnostics described by Katrin Grimm (2016,ISBN:978-3-8439-3092-5) can be computed. Summary and plotting functions are provided.

This is a simple R package that allows to measure the stated preferences using traditional conjoint analysis method.

Solves control systems problems relating to time/frequency response, LTI systems design and analysis, transfer function manipulations, and system conversion.

This package implements the conditionally symmetric multidimensional Gaussian mixture model (csmGmm) for large-scale testing of composite null hypotheses in genetic association applications such as mediation analysis, pleiotropy analysis, and replication analysis. In such analyses, we typically have J sets of K test statistics where K is a small number (e.g. 2 or 3) and J is large (e.g. 1 million). For each one of the J sets, we want to know if we can reject all K individual nulls. Please see the vignette for a quickstart guide. The paper describing these methods is "Testing a Large Number of Composite Null Hypotheses Using Conditionally Symmetric Multidimensional Gaussian Mixtures in Genome-Wide Studies" by Sun R, McCaw Z, & Lin X (Journal of the American Statistical Association 2025, <doi:10.1080/01621459.2024.2422124>).