Count transformation models featuring parameters interpretable as discrete hazard ratios, odds ratios, reverse-time discrete hazard ratios, or transformed expectations. An appropriate data transformation for a count outcome and regression coefficients are simultaneously estimated by maximising the exact discrete log-likelihood using the computational framework provided in package mlt', technical details are given in Siegfried & Hothorn (2020) <DOI:10.1111/2041-210X.13383>. The package also contains an experimental implementation of multivariate count transformation models with an application to multi-species distribution models <DOI:10.48550/arXiv.2201.13095>.

This package provides a collection of functions to generate a large variety of structures in high dimensions. These data structures are useful for testing, validating, and improving algorithms used in dimensionality reduction, clustering, machine learning, and visualization.

Fast, optimal, and reproducible weighted univariate clustering by dynamic programming. Four problems are solved, including univariate k-means (Wang & Song 2011) <doi:10.32614/RJ-2011-015> (Song & Zhong 2020) <doi:10.1093/bioinformatics/btaa613>, k-median, k-segments, and multi-channel weighted k-means. Dynamic programming is used to minimize the sum of (weighted) within-cluster distances using respective metrics. Its advantage over heuristic clustering in efficiency and accuracy is pronounced when there are many clusters. Multi-channel weighted k-means groups multiple univariate signals into k clusters. An auxiliary function generates histograms adaptive to patterns in data. This package provides a powerful set of tools for univariate data analysis with guaranteed optimality, efficiency, and reproducibility, useful for peak calling on temporal, spatial, and spectral data.

Functionality to perform adaptive multi-wave sampling for efficient chart validation. Code allows one to define strata, adaptively sample using several types of confidence bounds for the quantity of interest (Lai's confidence bands, Bayesian credible intervals, normal confidence intervals), and sampling strategies (random sampling, stratified random sampling, Neyman's sampling, see Neyman (1934) <doi:10.2307/2342192> and Neyman (1938) <doi:10.1080/01621459.1938.10503378>).

This package provides essential Cleaning Validation functions for complying with pharmaceutical cleaning process regulatory standards. The package includes non-parametric methods to analyze drug active-ingredient residue (DAR), cleaning agent residue (CAR), and microbial colonies (Mic) for non-Poisson distributions. Additionally, Poisson methods are provided for Mic analysis when Mic data follow a Poisson distribution.

This package provides a finite mixture of Zero-Inflated Poisson (ZIP) models for analyzing criminal trajectories.

Interface to the Google Cloud Machine Learning Platform <https://cloud.google.com/vertex-ai>, which provides cloud tools for training machine learning models.

Noise in the time-series data significantly affects the accuracy of the Machine Learning (ML) models (Artificial Neural Network and Support Vector Regression are considered here). Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (CEEMDAN) decomposes the time series data into sub-series and help to improve the model performance. The models can achieve higher prediction accuracy than the traditional ML models. Two models have been provided here for time series forecasting. More information may be obtained from Garai and Paul (2023) <doi:10.1016/j.iswa.2023.200202>.

This package implements the iterated RMCD method of Cerioli (2010) for multivariate outlier detection via robust Mahalanobis distances. Also provides the finite-sample RMCD method discussed in the paper, as well as the methods provided in Hardin and Rocke (2005) <doi:10.1198/106186005X77685> and Green and Martin (2017) <https://christopherggreen.github.io/papers/hr05_extension.pdf>. See also Chapter 2 of Green (2017) <https://digital.lib.washington.edu/researchworks/handle/1773/40304>.

This package provides a suite of computer model test functions that can be used to test and evaluate algorithms for Bayesian (also known as sequential) optimization. Some of the functions have known functional forms, however, most are intended to serve as black-box functions where evaluation requires running computer code that reveals little about the functional forms of the objective and/or constraints. The primary goal of the package is to provide users (especially those who do not have access to real computer models) a source of reproducible and shareable examples that can be used for benchmarking algorithms. The package is a living repository, and so more functions will be added over time. For function suggestions, please do contact the author of the package.

Circular drift-diffusion model for continuous reports.

Package encapsulates standard expressions for distances, times, luminosities, and other quantities useful in observational cosmology, including molecular line observations. Currently coded for a flat universe only.

Mines contiguous sequential patterns in text.

This package provides a uniform statistical inferential tool in making individualized treatment decisions, which implements the methods of Ma et al. (2017)<DOI:10.1177/0962280214541724> and Guo et al. (2021)<DOI:10.1080/01621459.2020.1865167>. It uses a flexible semiparametric modeling strategy for heterogeneous treatment effect estimation in high-dimensional settings and can gave valid confidence bands. Based on it, one can find the subgroups of patients that benefit from each treatment, thereby making individualized treatment selection.

Procedures include Phillips (1995) FMVAR <doi:10.2307/2171721>, Kitamura and Phillips (1997) FMGMM <doi:10.1016/S0304-4076(97)00004-3>, Park (1992) CCR <doi:10.2307/2951679>, and so on. Tests with 1 or 2 structural breaks include Gregory and Hansen (1996) <doi:10.1016/0304-4076(69)41685-7>, Zivot and Andrews (1992) <doi:10.2307/1391541>, and Kurozumi (2002) <doi:10.1016/S0304-4076(01)00106-3>.

Implementations of recent complex-valued wavelet spectral procedures for analysis of irregularly sampled signals, see Hamilton et al (2018) <doi:10.1080/00401706.2017.1281846>.

Computes effect sizes, standard errors, and confidence intervals for total, direct, and indirect effects in continuous-time mediation models as described in Pesigan, Russell, and Chow (2025) <doi:10.1037/met0000779>.

This package provides SPSS'- and SAS'-like output for cross tabulations of two categorical variables (CROSSTABS) and for hierarchical loglinear analyses of two or more categorical variables (LOGLINEAR). The methods are described in Agresti (2013, ISBN:978-0-470-46363-5), Ajzen & Walker (2021, ISBN:9780429330308), Field (2018, ISBN:9781526440273), Norusis (2012, ISBN:978-0-321-74843-0), Nussbaum (2015, ISBN:978-1-84872-603-1), Stevens (2009, ISBN:978-0-8058-5903-4), Tabachnik & Fidell (2019, ISBN:9780134790541), and von Eye & Mun (2013, ISBN:978-1-118-14640-8).

It computes full conformal, split conformal and multi split conformal prediction regions when the response has functional nature. Moreover, the package also contain a plot function to visualize the output of the split conformal. To guarantee consistency, the package structure mimics the univariate conformalInference package of professor Ryan Tibshirani. The main references for the code are: Diquigiovanni, Fontana, and Vantini (2021) <arXiv:2102.06746>, Diquigiovanni, Fontana, and Vantini (2021) <arXiv:2106.01792>, Solari, and Djordjilovic (2021) <arXiv:2103.00627>.

Network-based clustering using a Bayesian network mixture model with optional covariate adjustment.

This package provides functions to perform the following analyses: i) inferring epistasis from RNAi double knockdown data; ii) identifying gene pairs of multiple mutation patterns; iii) assessing association between gene pairs and survival; and iv) calculating the smallworldness of a graph (e.g., a gene interaction network). Data and analyses are described in Wang, X., Fu, A. Q., McNerney, M. and White, K. P. (2014). Widespread genetic epistasis among breast cancer genes. Nature Communications. 5 4828. <doi:10.1038/ncomms5828>.

This package provides simplified access to the data from the Catalog of Theses and Dissertations of the Brazilian Coordination for the Improvement of Higher Education Personnel (CAPES, <https://catalogodeteses.capes.gov.br>) for the years 1987 through 2022. The dataset includes variables such as Higher Education Institution (institution), Area of Concentration (area), Graduate Program Name (program_name), Type of Work (type), Language of Work (language), Author Identification (author), Abstract (abstract), Advisor Identification (advisor), Development Region (region), State (state).

Computing elliptical joint confidence regions at a specified confidence level. It provides the flexibility to estimate either classical or robust confidence regions, which can be visualized in 2D or 3D plots. The classical approach assumes normality and uses the mean and covariance matrix to define the confidence regions. Alternatively, the robustified version employs estimators like minimum covariance determinant (MCD) and M-estimator, making them less sensitive to outliers and departures from normality. Furthermore, the functions allow users to group the dataset based on categorical variables and estimate separate confidence regions for each group. This capability is particularly useful for exploring potential differences or similarities across subgroups within a dataset. Varmuza and Filzmoser (2009, ISBN:978-1-4200-5947-2). Johnson and Wichern (2007, ISBN:0-13-187715-1). Raymaekers and Rousseeuw (2019) <DOI:10.1080/00401706.2019.1677270>.

Reads and writes CSV with selected conventions. Uses the same generic function for reading and writing to promote consistent formats.