Deconvolution of bulk RNA-Sequencing data into proportions of cells based on a reference single-cell RNA-Sequencing dataset using high-dimensional geometric methodology.

Augment clinical data with metadata to create output used in conventional publications and reports.

This package provides a collection of functions that make it easier to understand crime (or other) data, and assist others in understanding it. The package helps you read data from various sources, clean it, fix column names, and graph the data.

Modeling periodic mortality (or other time-to event) processes from right-censored data. Given observations of a process with a known period (e.g. 365 days, 24 hours), functions determine the number, intensity, timing, and duration of peaks of periods of elevated hazard within a period. The underlying model is a mixed wrapped Cauchy function fitted using maximum likelihoods (details in Gurarie et al. (2020) <doi:10.1111/2041-210X.13305>). The development of these tools was motivated by the strongly seasonal mortality patterns observed in many wild animal populations. Thus, the respective periods of higher mortality can be identified as "mortality seasons".

This package provides a set of functions to fit a boosting conditional logit model.

This package provides a shortcut procedure is proposed to implement closed testing for large-scale multiple testings, especially with the global test. This shortcut is asymptotically equivalent to closed testing and post hoc. Users could detect any possible sets of features or pathways with family-wise error rate controlled. The global test is powerful to detect associations between a group of features and an outcome of interest.

Assesses the quality of estimates made by complex sample designs, following the methodology developed by the National Institute of Statistics Chile (Household Survey Standard 2020, <https://www.ine.cl/docs/default-source/institucionalidad/buenas-pr%C3%A1cticas/clasificaciones-y-estandares/est%C3%A1ndar-evaluaci%C3%B3n-de-calidad-de-estimaciones-publicaci%C3%B3n-27022020.pdf>), (Economics Survey Standard 2024, <https://www.ine.gob.cl/docs/default-source/buenas-practicas/directrices-metodologicas/estandares/documentos/est%C3%A1ndar-evaluaci%C3%B3n-de-calidad-de-estimaciones-econ%C3%B3micas.pdf?sfvrsn=201fbeb9_2>) and by Economic Commission for Latin America and Caribbean (2020, <https://repositorio.cepal.org/bitstream/handle/11362/45681/1/S2000293_es.pdf>), (2024, <https://repositorio.cepal.org/server/api/core/bitstreams/f04569e6-4f38-42e7-a32b-e0b298e0ab9c/content>).

Access chemical, hazard, bioactivity, and exposure data from the Computational Toxicology and Exposure ('CTX') APIs <https://www.epa.gov/comptox-tools/computational-toxicology-and-exposure-apis>. ctxR was developed to streamline the process of accessing the information available through the CTX APIs without requiring prior knowledge of how to use APIs. Most data is also available on the CompTox Chemical Dashboard ('CCD') <https://comptox.epa.gov/dashboard/> and other resources found at the EPA Computational Toxicology and Exposure Online Resources <https://www.epa.gov/comptox-tools>.

This package provides peruvian agricultural production data from the Agriculture Minestry of Peru (MINAGRI). The first version includes 6 crops: rice, quinoa, potato, sweet potato, tomato and wheat; all of them across 24 departments. Initially, in excel files which has been transformed and assembled using tidy data principles, i.e. each variable is in a column, each observation is a row and each value is in a cell. The variables variables are sowing and harvest area per crop, yield, production and price per plot, every one year, from 2004 to 2014.

This package implements the Centroid Decision Forest (CDF) as a single user-facing function CDF(). The method selects discriminative features via a multi-class class separability score (CSS), splits by nearest class centroid, and aggregates tree votes to produce predictions and class probabilities. Returns CSS-based feature importance as well. Amjad Ali, Saeed Aldahmani, Zardad Khan (2025) <doi:10.48550/arXiv.2503.19306>.

Estimation and goodness-of-fit functions for copula-based models of bivariate data with arbitrary distributions (discrete, continuous, mixture of both types). The copula families considered here are the Gaussian, Student, Clayton, Frank, Gumbel, Joe, Plackett, BB1, BB6, BB7,BB8, together with the following non-central squared copula families in Nasri (2020) <doi:10.1016/j.spl.2020.108704>: ncs-gaussian, ncs-clayton, ncs-gumbel, ncs-frank, ncs-joe, and ncs-plackett. For theoretical details, see, e.g., Nasri and Remillard (2023) <arXiv:2301.13408>.

Calculating the fractal dimension of a coastline using the boxes and dividers methods.

Allows users to input their data, segmentation and function used for the segmentation (and additional arguments) and the package calculates the influence of the data on the changepoint locations, see Wilms et al. (2022) <doi:10.1080/10618600.2021.2000873>. Currently this can only be used with the changepoint package functions to identify changes, but we plan to extend this. There are options for different types of graphics to assess the influence.

Utilize the shiny interface for visualizing results from a pyDarwin (<https://certara.github.io/pyDarwin/>) machine learning pharmacometric model search. It generates Goodness-of-Fit plots and summary tables for selected models, allowing users to customize diagnostic outputs within the interface. The underlying R code for generating plots and tables can be extracted for use outside the interactive session. Model diagnostics can also be incorporated into an R Markdown document and rendered in various output formats.

The Core Microbiome refers to the group of microorganisms that are consistently present in a particular environment, habitat, or host species. These microorganisms play a crucial role in the functioning and stability of that ecosystem. Identifying these microorganisms can contribute to the emerging field of personalized medicine. The CoreMicrobiomeR is designed to facilitate the identification, statistical testing, and visualization of this group of microorganisms.This package offers three key functions to analyze and visualize microbial community data. This package has been developed based on the research papers published by Pereira et al.(2018) <doi:10.1186/s12864-018-4637-6> and Beule L, Karlovsky P. (2020) <doi:10.7717/peerj.9593>.

This package implements the Bayesian calibration model described in Pratola and Chkrebtii (2018) <DOI:10.5705/ss.202016.0403> for stochastic and deterministic simulators. Additive and multiplicative discrepancy models are currently supported. See <http://www.matthewpratola.com/software> for more information and examples.

Defines classes and methods to cross-validate various binary classification algorithms used for "class prediction" problems.

The developed function is a comprehensive tool for the analysis of India Meteorological Department (IMD) NetCDF rainfall data. Specifically designed to process high-resolution daily gridded rainfall datasets. It provides four key functions to process IMD NetCDF rainfall data and create rasters for various temporal scales, including annual, seasonal, monthly, and weekly rainfall. For method details see, Malik, A. (2019).<DOI:10.1007/s12517-019-4454-5>. It supports different aggregation methods, such as sum, min, max, mean, and standard deviation. These functions are designed for spatio-temporal analysis of rainfall patterns, trend analysis,geostatistical modeling of rainfall variability, identifying rainfall anomalies and extreme events and can be an input for hydrological and agricultural models.

This package provides function declarations and inline function definitions that facilitate communication between R and the Eigen C++ library for linear algebra and scientific computing.

This package performs survival analysis using general non-linear models. Risk models can be the sum or product of terms. Each term is the product of exponential/linear functions of covariates. Additionally sub-terms can be defined as a sum of exponential, linear threshold, and step functions. Cox Proportional hazards <https://en.wikipedia.org/wiki/Proportional_hazards_model>, Poisson <https://en.wikipedia.org/wiki/Poisson_regression>, and Fine-Gray competing risks <https://www.publichealth.columbia.edu/research/population-health-methods/competing-risk-analysis> regression are supported. This work was sponsored by NASA Grants 80NSSC19M0161 and 80NSSC23M0129 through a subcontract from the National Council on Radiation Protection and Measurements (NCRP). The computing for this project was performed on the Beocat Research Cluster at Kansas State University, which is funded in part by NSF grants CNS-1006860, EPS-1006860, EPS-0919443, ACI-1440548, CHE-1726332, and NIH P20GM113109.

Compare two classifications or clustering solutions that may or may not have the same number of classes, and that might have hard or soft (fuzzy, probabilistic) membership. Calculate various metrics to assess how the clusters compare to each other. The calculations are simple, but provide a handy tool for users unfamiliar with matrix multiplication. This package is not geared towards traditional accuracy assessment for classification/ mapping applications - the motivating use case is for comparing a probabilistic clustering solution to a set of reference or existing class labels that could have any number of classes (that is, without having to degrade the probabilistic clustering to hard classes).

This package implements the framework introduced in Di Francesco and Mellace (2025) <doi:10.48550/arXiv.2502.11691>, shifting the focus to well-defined and interpretable estimands that quantify how treatment affects the probability distribution over outcome categories. It supports selection-on-observables, instrumental variables, regression discontinuity, and difference-in-differences designs.

Helpful functions for the cleaning and manipulation of surveillance data, especially with regards to the creation and validation of panel data from individual level surveillance data.

Geometric circle fitting with Levenberg-Marquardt (a, b, R), Levenberg-Marquardt reduced (a, b), Landau, Spath and Chernov-Lesort. Algebraic circle fitting with Taubin, Kasa, Pratt and Fitzgibbon-Pilu-Fisher. Geometric ellipse fitting with ellipse LMG (geometric parameters) and conic LMA (algebraic parameters). Algebraic ellipse fitting with Fitzgibbon-Pilu-Fisher and Taubin.