Cure dependent censoring regression models for long-term survival multivariate data. These models are based on extensions of the frailty models, capable to accommodating the cure fraction and the dependence between failure and censoring times, with Weibull and piecewise exponential marginal distributions. Theoretical details regarding the models implemented in the package can be found in Schneider et al. (2022) <doi:10.1007/s10651-022-00549-0>.

Convolute probabilistic distributions using the random generator function of each distribution. A new random number generator function is created that perform the mathematical operation on the individual random samples from the random generator function of each distribution. See the documentation for examples.

Model building, surrogate model based optimization and Efficient Global Optimization in combinatorial or mixed search spaces.

This package provides a tool for matching ICD-10 codes to corresponding Clinical Classification Software Refined (CCSR) codes. The main function, CCSRfind(), identifies each CCSR code that applies to an individual given their diagnosis codes. It also provides a summary of CCSR codes that are matched to a dataset. The package contains 3 datasets: DXCCSR (mapping of ICD-10 codes to CCSR codes), Legend (conversion of DXCCSR to CCSRfind-usable format for CCSR codes with less than or equal to 1000 ICD-10 diagnosis codes), and LegendExtend (conversion of DXCCSR to CCSRfind-usable format for CCSR codes with more than 1000 ICD-10 dx codes). The disc() function applies grepl() ('base') to multiple columns and is used in CCSRfind().

R interface for RAPIDS cuML (<https://github.com/rapidsai/cuml>), a suite of GPU-accelerated machine learning libraries powered by CUDA (<https://en.wikipedia.org/wiki/CUDA>).

Composite likelihood approach is implemented to estimating statistical models for spatial ordinal and proportional data based on Feng et al. (2014) <doi:10.1002/env.2306>. Parameter estimates are identified by maximizing composite log-likelihood functions using the limited memory BFGS optimization algorithm with bounding constraints, while standard errors are obtained by estimating the Godambe information matrix.

Population ratio estimator (calibrated) under two-phase random sampling design has gained enormous popularity in the recent time. This package provides functions for estimation population ratio (calibrated) under two phase sampling design, including the approximate variance of the ratio estimator. The improved ratio estimator can be applicable for both the case, when auxiliary data is available at unit level or aggregate level (eg., mean or total) for first phase sampled. Calibration weight of each unit of the second phase sample was calculated. Single and combined inclusion probabilities were also estimated for both phases under two phase random [simple random sampling without replacement (SRSWOR)] sampling. The improved ratio estimator's percentage coefficient of variation was also determined as a measure of accuracy. This package has been developed based on the theoretical development of Islam et al. (2021) and Ozgul (2020) <doi:10.1080/00949655.2020.1844702>.

This package provides comprehensive cytokine profiling analysis through quality control using biologically meaningful cutoffs on raw cytokine measurements and by testing for distributional symmetry to recommend appropriate transformations. Offers exploratory data analysis with summary statistics, enhanced boxplots, and barplots, along with univariate and multivariate analytical capabilities for in-depth cytokine profiling such as Principal Component Analysis based on Andrzej MaÄ kiewicz and Waldemar Ratajczak (1993) <doi:10.1016/0098-3004(93)90090-R>, Sparse Partial Least Squares Discriminant Analysis based on Lê Cao K-A, Boitard S, and Besse P (2011) <doi:10.1186/1471-2105-12-253>, Random Forest based on Breiman, L. (2001) <doi:10.1023/A:1010933404324>, and Extreme Gradient Boosting based on Tianqi Chen and Carlos Guestrin (2016) <doi:10.1145/2939672.2939785>.

Predict Scope 1, 2 and 3 carbon emissions for UK Small and Medium-sized Enterprises (SMEs), using Standard Industrial Classification (SIC) codes and annual turnover data, as well as Scope 1 carbon emissions for UK farms. The carbonpredict package provides single and batch prediction, plotting, and workflow tools for carbon accounting and reporting. The package utilises pre-trained models, leveraging rich classified transaction data to accurately predict Scope 1, 2 and 3 carbon emissions for UK SMEs as well as identifying emissions hotspots. It also provides Scope 1 carbon emissions predictions for UK farms of types: Cereals ex. rice, Dairy, Mixed farming, Sheep and goats, Cattle & buffaloes, Poultry, Animal production and Support for crop production. The methodology used to produce the estimates in this package is fully detailed in the following peer-reviewed publications: Phillpotts, A., Owen. A., Norman, J., Trendl, A., Gathergood, J., Jobst, Norbert., Leake, D. (2025) <doi:10.1111/jiec.70106> "Bridging the SME Reporting Gap: A New Model for Predicting Scope 1 and 2 Emissions" and Wells, J., Trendl, A., Owen, A., Barrett, J., Gridley, J., Jobst, N., Leake, D. (2025) <doi:10.1088/1748-9326/ae20ab> "A Scalable Tool for Farm-Level Carbon Accounting: Evidence from UK Agriculture".

For those wishing to interact with the Charles Schwab Individual Trader API (<https://developer.schwab.com/products/trader-api--individual>) with R in a simplified manner, this package offers wrapper functions around authentication and the available API calls to streamline the process.

Provide a series of functions to conduct a meta analysis of factor analysis based on co-occurrence matrices. The tool can be used to solve the factor structure (i.e. inner structure of a construct, or scale) debate in several disciplines, such as psychology, psychiatry, management, education so on. References: Shafer (2005) <doi:10.1037/1040-3590.17.3.324>; Shafer (2006) <doi:10.1002/jclp.20213>; Loeber and Schmaling (1985) <doi:10.1007/BF00910652>.

This package provides means of plots for comparing utilization data of compute systems.

This package provides a tool to easily run and visualise supervised and unsupervised state of the art customer segmentation. It is built like a pipeline covering the 3 main steps in a segmentation project: pre-processing, modelling, and plotting. Users can either run the pipeline as a whole, or choose to run any one of the three individual steps. It is equipped with a supervised option (tree optimisation) and an unsupervised option (k-clustering) as default models.

Implement various chromosomal instability metrics. CINmetrics (Chromosomal INstability metrics) provides functions to calculate various chromosomal instability metrics on masked Copy Number Variation(CNV) data at individual sample level. The chromosomal instability metrics have been implemented as described in the following studies: Baumbusch LO et al. 2013 <doi:10.1371/journal.pone.0054356>, Davidson JM et al. 2014 <doi:10.1371/journal.pone.0079079>, Chin SF et al. 2007 <doi:10.1186/gb-2007-8-10-r215>.

This package provides a multiple testing procedure for clustered alternative hypotheses. It is assumed that the p-values under the null hypotheses follow U(0,1) and that the distributions of p-values from the alternative hypotheses are stochastically smaller than U(0,1). By aggregating information, this method is more sensitive to detecting signals of low magnitude than standard methods. Additionally, sporadic small p-values appearing within a null hypotheses sequence are avoided by averaging on the neighboring p-values.

This package implements cross-validation methods for linear and ridge regression models. The package provides grid-based selection of the ridge penalty parameter using Singular Value Decomposition (SVD) and supports K-fold cross-validation, Leave-One-Out Cross-Validation (LOOCV), and Generalized Cross-Validation (GCV). Computations are implemented in C++ via RcppArmadillo with optional parallelization using RcppParallel'. The methods are suitable for high-dimensional settings where the number of predictors exceeds the number of observations.

This package provides functions for fitting univariate linear regression models under Scale Mixtures of Skew-Normal (SMSN) distributions, considering left, right or interval censoring and missing responses. Estimation is performed via an EM-type algorithm. Includes selection criteria, sample generation and envelope. For details, see Gil, Y.A., Garay, A.M., and Lachos, V.H. (2025) <doi:10.1007/s10260-025-00797-x>.

This package implements Cragg-Donald (1993) <doi:10.1017/S0266466600007519> and Stock and Yogo (2005) <doi:10.1017/CBO9780511614491.006> tests for weak instruments in R.

This package provides data on countries and their main city or agglomeration and the different distance measures and dummy variables indicating whether two countries are contiguous, share a common language or a colonial relationship. The reference article for these datasets is Mayer and Zignago (2011) <http://www.cepii.fr/CEPII/en/publications/wp/abstract.asp?NoDoc=3877>.

Indicators and measures by country and time describe what happens at economic and social levels. This package provides functions to calculate several measures of convergence after imputing missing values. The automated downloading of Eurostat data, followed by the production of country fiches and indicator fiches, makes possible to produce automated reports. The Eurofound report (<doi:10.2806/68012>) "Upward convergence in the EU: Concepts, measurements and indicators", 2018, is a detailed presentation of convergence.

Data manipulation for Coupled Model Intercomparison Project, Phase-6 (CMIP6) hydroclimatic data. The files are archived in the Federated Research Data Repository (FRDR) (Rajulapati et al, 2024, <doi:10.20383/103.0829>). The data set is described in Abdelmoaty et al. (2025, <doi:10.1038/s41597-025-04396-z>).

Generates the scripts required to create an Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) database and associated documentation for supported database platforms. Leverages the SqlRender package to convert the Data Definition Language (DDL) script written in parameterized Structured Query Language (SQL) to the other supported dialects.

This package provides tools that allow developers to write functions for cross-validation with minimal programming effort and assist users with model selection.

Implementation of Librino, Levorato, and Zorzi (2014) <doi:10.1002/wcm.2305> algorithm for computation of the intersection areas of an arbitrary number of circles.