We unify various nonparametric hypothesis testing problems in a framework of permutation testing, enabling hypothesis testing on multi-sample, multidimensional data and contingency tables. Most of the functions available in the R environment to implement permutation tests are single functions constructed for specific test problems; to facilitate the use of the package, the package encapsulates similar tests in a categorized manner, greatly improving ease of use. We will all provide functions for self-selected permutation scoring methods and self-selected p-value calculation methods (asymptotic, exact, and sampling). For two-sample tests, we will provide mean tests and estimate drift sizes; we will provide tests on variance; we will provide paired-sample tests; we will provide correlation coefficient tests under three measures. For multi-sample problems, we will provide both ordinary and ordered alternative test problems. For multidimensional data, we will implement multivariate means (including ordered alternatives) and multivariate pairwise tests based on four statistics; the components with significant differences are also calculated. For contingency tables, we will perform permutation chi-square test or ordered alternative.

This package creates an HTML vertical timeline from a data frame as an input for rmarkdown documents and shiny applications.

This package provides methods and functions to implement a Recommendation System based on Collaborative Filtering Methodology. See Aggarwal (2016) <doi:10.1007/978-3-319-29659-3> for an overview.

Generates tree plots with precise branch lengths, gene annotations, and cellular prevalence. The package handles complex tree structures (angles, lengths, etc.) and can be further refined as needed by the user.

Clique percolation community detection for weighted and unweighted networks as well as threshold and plotting functions. For more information see Farkas et al. (2007) <doi:10.1088/1367-2630/9/6/180> and Palla et al. (2005) <doi:10.1038/nature03607>.

This package provides a minimum set of functions to perform compositional data analysis using the log-ratio approach introduced by John Aitchison (1982). Main functions have been implemented in c++ for better performance.

Comparison of two ROC curves through the methodology proposed by Ana C. Braga.

Statistical tests for the comparison between two correlations based on either independent or dependent groups. Dependent correlations can either be overlapping or nonoverlapping. A web interface is available on the website <http://comparingcorrelations.org>. A plugin for the R GUI and IDE RKWard is included. Please install RKWard from <https://rkward.kde.org> to use this feature. The respective R package rkward cannot be installed directly from a repository, as it is a part of RKWard.

Biotechnology in spatial omics has advanced rapidly over the past few years, enhancing both throughput and resolution. However, existing annotation pipelines in spatial omics predominantly rely on clustering methods, lacking the flexibility to integrate extensive annotated information from single-cell RNA sequencing (scRNA-seq) due to discrepancies in spatial resolutions, species, or modalities. Here we introduce the CAESAR suite, an open-source software package that provides image-based spatial co-embedding of locations and genomic features. It uniquely transfers labels from scRNA-seq reference, enabling the annotation of spatial omics datasets across different technologies, resolutions, species, and modalities, based on the conserved relationship between signature genes and cells/locations at an appropriate level of granularity. Notably, CAESAR enriches location-level pathways, allowing for the detection of gradual biological pathway activation within spatially defined domain types. More details on the methods related to our paper currently under submission. A full reference to the paper will be provided in future versions once the paper is published.

Checks that students have the correct version of R', R packages, RStudio and other dependencies installed, and that the recommended RStudio configuration has been applied.

The CloudOS client library for R makes it easy to interact with CloudOS in the R environment for analysis.

ClickHouse (<https://clickhouse.com/>) is an open-source, high performance columnar OLAP (online analytical processing of queries) database management system for real-time analytics using SQL. This DBI backend relies on the ClickHouse HTTP interface and support HTTPS protocol.

This package performs forward model selection, using the C-index/concordance in survival analysis models.

Augment clinical data with metadata to create output used in conventional publications and reports.

Fast application of Continuous Wavelet Transformation ('CWT') on time series with special attention to spectroscopy. It is written using data.table and C++ language and in some functions it is possible to use parallel processing to speed-up the computation over samples. Currently, only the second derivative of a Gaussian wavelet function is implemented.

Climate stability measures are not formalized in the literature and tools for generating stability metrics from existing data are nascent. This package provides tools for calculating climate stability from raster data encapsulating climate change as a series of time slices. The methods follow Owens and Guralnick <doi:10.17161/bi.v14i0.9786> Biodiversity Informatics.

This package provides functions designed to simulate data that conform to basic unidimensional IRT models (for now 3-parameter binary response models and graded response models) along with Post-Hoc CAT simulations of those models given various item selection methods, ability estimation methods, and termination criteria. See Wainer (2000) <doi:10.4324/9781410605931>, van der Linden & Pashley (2010) <doi:10.1007/978-0-387-85461-8_1>, and Eggen (1999) <doi:10.1177/01466219922031365> for more details.

Computes the cosine-correlation coefficient for measuring the degree of linear dependence among variables in a multidimensional context. The package implements the generalized cosine-correlation theorem for p-1 variables, providing a quantitative assessment of interrelationships within experimental frameworks. This methodology extends classical correlation measures to higher-dimensional spaces using a dimensional exploration approach based on time scale calculus.

Doubly robust estimation and inference of log hazard ratio under the Cox marginal structural model with informative censoring. An augmented inverse probability weighted estimator that involves 3 working models, one for conditional failure time T, one for conditional censoring time C and one for propensity score. Both models for T and C can depend on both a binary treatment A and additional baseline covariates Z, while the propensity score model only depends on Z. With the help of cross-fitting techniques, achieves the rate-doubly robust property that allows the use of most machine learning or non-parametric methods for all 3 working models, which are not permitted in classic inverse probability weighting or doubly robust estimators. When the proportional hazard assumption is violated, CoxAIPW estimates a causal estimated that is a weighted average of the time-varying log hazard ratio. Reference: Luo, J. (2023). Statistical Robustness - Distributed Linear Regression, Informative Censoring, Causal Inference, and Non-Proportional Hazards [Unpublished doctoral dissertation]. University of California San Diego.; Luo & Xu (2022) <doi:10.48550/arXiv.2206.02296>; Rava (2021) <https://escholarship.org/uc/item/8h1846gs>.

This package provides a system for creating R Markdown reports with a sequential syntax.

This package implements the Bayesian calibration model described in Pratola and Chkrebtii (2018) <DOI:10.5705/ss.202016.0403> for stochastic and deterministic simulators. Additive and multiplicative discrepancy models are currently supported. See <http://www.matthewpratola.com/software> for more information and examples.

This package provides tools for sampling from a conditional copula density decomposed via Pair-Copula Constructions as C- or D- vine. Here, the vines which can be used for such a sampling are those which sample as first the conditioning variables (when following the sampling algorithms shown in Aas et al. (2009) <DOI:10.1016/j.insmatheco.2007.02.001>). The used sampling algorithm is presented and discussed in Bevacqua et al. (2017) <DOI:10.5194/hess-2016-652>, and it is a modified version of that from Aas et al. (2009) <DOI:10.1016/j.insmatheco.2007.02.001>. A function is available to select the best vine (based on information criteria) among those which allow for such a conditional sampling. The package includes a function to compare scatterplot matrices and pair-dependencies of two multivariate datasets.

An interface to the cycle routing/data services provided by CycleStreets', a not-for-profit social enterprise and advocacy organisation. The application programming interfaces (APIs) provided by CycleStreets are documented at (<https://www.cyclestreets.net/api/>). The focus of this package is the journey planning API, which aims to emulate the routes taken by a knowledgeable cyclist. An innovative feature of the routing service of its provision of fastest, quietest and balanced profiles. These represent routes taken to minimise time, avoid traffic and compromise between the two, respectively.

Data sets used for copula modeling in addition to those in the R package copula'. These include a random subsample from the US National Education Longitudinal Study (NELS) of 1988 and nursing home data from Wisconsin.