Automated assessment and selection of weighting factors for accurate quantification using linear calibration curve. In addition, a shiny App is provided, allowing users to analyze their data using an interactive graphical user interface, without any programming requirements.

Identification and visualization of groups of closely spaced mutations in the DNA sequence of cancer genome. The extremely mutated zones are searched in the symmetric dissimilarity matrix using the anti-Robinson matrix properties. Different data sets are obtained to describe and plot the clustered mutations information.

This package implements higher order likelihood-based inference for logistic and loglinear models.

This package provides a consistent interface for connecting R to various data sources including file systems and databases. Designed for clinical research, connector streamlines access to ADAM', SDTM for example. It helps to deal with multiple data formats through a standardized API and centralized configuration.

Enable seamless interaction with Consibio Cloud <https://consibio.cloud> API <https://api.v2.consibio.com/api-docs/>. This package provides tools to query data from resources like projects, elements, devices, and datalogs.

Conditional mixture model fitted via EM (Expectation Maximization) algorithm for model-based clustering, including parsimonious procedure, optimal conditional order exploration, and visualization.

Utility functions to facilitate the import, the reporting and analysis of clinical data. Example datasets in SDTM and ADaM format, containing a subset of patients/domains from the CDISC Pilot 01 study are also available as R datasets to demonstrate the package functionalities.

Design functions for DCMs and other types of choice studies (including MaxDiff and other tradeoffs).

Implementation of a procedure---Domingue (2012) <https://eric.ed.gov/?id=ED548657>, Domingue (2014) <doi:10.1007/s11336-013-9342-4>; see also Karabatsos (2001) <https://psycnet.apa.org/record/2002-01665-005> and Kyngdon (2011) <doi:10.1348/2044-8317.002004>---to test the single and double cancellation axioms of conjoint measure in data that is dichotomously coded and measured with error.

Allows you to conduct robust correlations on your non-normal data set. The robust correlations included in the package are median-absolute-deviation and median-based correlations. Li, J.C.H. (2022) <doi:10.5964/meth.8467>.

Cronbach's alpha and McDonald's omega are widely used reliability or internal consistency measures in social, behavioral and education sciences. Alpha is reported in nearly every study that involves measuring a construct through multiple test items. The package coefficientalpha calculates coefficient alpha and coefficient omega with missing data and non-normal data. Robust standard errors and confidence intervals are also provided. A test is also available to test the tau-equivalent and homogeneous assumptions. Since Version 0.5, the bootstrap confidence intervals were added.

Implementation of the ageâ periodâ cohort models for claim development presented in Pittarello G, Hiabu M, Villegas A (2025) â Replicating and Extending Chainâ Ladder via an Ageâ Periodâ Cohort Structure on the Claim Development in a Runâ Off Triangleâ <doi:10.1080/10920277.2025.2496725>.

This package implements the algorithm described in Trapnell,C. et al. (2010) <doi: 10.1038/nbt.1621>. This function takes read counts matrix of RNA-Seq data, feature lengths which can be retrieved using biomaRt package, and the mean fragment lengths which can be calculated using the CollectInsertSizeMetrics(Picard) tool. It then returns a matrix of FPKM normalised data by library size and feature effective length. It also provides the user with a quick and reliable function to generate FPKM heatmap plot of the highly variable features in RNA-Seq dataset.

Compute Chinese capital stocks in provinces level, based on Zhang (2008) <DOI:10.1080/14765280802028302>.

This package provides comprehensive tools for extracting and analyzing scientific content from PDF documents, including citation extraction, reference matching, text analysis, and bibliometric indicators. Supports multi-column PDF layouts, CrossRef API <https://www.crossref.org/documentation/retrieve-metadata/rest-api/> integration, and advanced citation parsing.

Resampling is a standard step in particle filtering and in sequential Monte Carlo. This package implements the chopthin resampler, which keeps a bound on the ratio between the largest and the smallest weights after resampling.

General functions for convolutions of data. Moving average, running median, and other filters are available. Bibliography regarding the functions can be found in the following text. Richard G. Brereton (2003) <ISBN:9780471489771>.

Compute ranking and rating based on competition results. Methods of different nature are implemented: with fixed Head-to-Head structure, with variable Head-to-Head structure and with iterative nature. All algorithms are taken from the book Whoâ s #1?: The science of rating and ranking by Amy N. Langville and Carl D. Meyer (2012, ISBN:978-0-691-15422-0).

Offers several functions for Configural Frequencies Analysis (CFA), which is a useful statistical tool for the analysis of multiway contingency tables. CFA was introduced by G. A. Lienert as Konfigurations Frequenz Analyse - KFA'. Lienert, G. A. (1971). Die Konfigurationsfrequenzanalyse: I. Ein neuer Weg zu Typen und Syndromen. Zeitschrift für Klinische Psychologie und Psychotherapie, 19(2), 99â 115.

This package provides functions to create contour-enhanced forest plots for meta-analysis, supporting binary outcomes (e.g., odds ratios, risk ratios), continuous outcomes (e.g., correlations), and prevalence estimates. Includes options for prediction intervals, customized colors, study labeling, and contour shading to highlight regions of statistical significance. Based on metafor and ggplot2'.

Given a non-linear model, calculate the local explanation. We purpose view the data space, explanation space, and model residuals as ensemble graphic interactive on a shiny application. After an observation of interest is identified, the normalized variable importance of the local explanation is used as a 1D projection basis. The support of the local explanation is then explored by changing the basis with the use of the radial tour <doi:10.32614/RJ-2020-027>; <doi:10.1080/10618600.1997.10474754>.

Matrix-variate covariance estimation via the Kronecker-core decomposition. Computes the Kronecker and core covariance matrices corresponding to an arbitrary covariance matrix, and provides an empirical Bayes covariance estimator that adaptively shrinks towards the space of separable covariance matrices. For details, see Hoff, McCormack and Zhang (2022) <arXiv:2207.12484> "Core Shrinkage Covariance Estimation for Matrix-variate data".

This package provides tools for measuring the compositionality of signalling systems (in particular the information-theoretic measure due to Spike (2016) <http://hdl.handle.net/1842/25930> and the Mantel test for distance matrix correlation (after Dietz 1983) <doi:10.1093/sysbio/32.1.21>), functions for computing string and meaning distance matrices as well as an implementation of the Page test for monotonicity of ranks (Page 1963) <doi:10.1080/01621459.1963.10500843> with exact p-values up to k = 22.

Automatize downloading of meteorological and hydrological data from publicly available repositories: OGIMET (<http://ogimet.com/index.phtml.en>), University of Wyoming - atmospheric vertical profiling data (<http://weather.uwyo.edu/upperair/>), Polish Institute of Meteorology and Water Management - National Research Institute (<https://danepubliczne.imgw.pl>), and National Oceanic & Atmospheric Administration (NOAA). This package also allows for searching geographical coordinates for each observation and calculate distances to the nearest stations.