Generates tree plots with precise branch lengths, gene annotations, and cellular prevalence. The package handles complex tree structures (angles, lengths, etc.) and can be further refined as needed by the user.

Calculate the predictive discrete Fourier transform, complete discrete Fourier transform, complete periodogram, and tapered complete periodogram. This algorithm is based on the preprint "Spectral methods for small sample time series: A complete periodogram approach" (2020) by Sourav Das, Suhasini Subba Rao, and Junho Yang.

In searching for research articles, we often want to obtain lists of references from across studies, and also obtain lists of articles that cite a particular study. In systematic reviews, this supplementary search technique is known as citation chasing': forward citation chasing looks for all records citing one or more articles of known relevance; backward citation chasing looks for all records referenced in one or more articles. Traditionally, this process would be done manually, and the resulting records would need to be checked one-by-one against included studies in a review to identify potentially relevant records that should be included in a review. This package contains functions to automate this process by making use of the Lens.org API. An input article list can be used to return a list of all referenced records, and/or all citing records in the Lens.org database (consisting of PubMed, PubMed Central, CrossRef, Microsoft Academic Graph and CORE; <https://www.lens.org>).

Light-weight functions for computing descriptive statistics in different circular spaces (e.g., 2pi, 180, or 360 degrees), to handle angle-dependent biases, pad circular data, and more. Specifically aimed for psychologists and neuroscientists analyzing circular data. Basic methods are based on Jammalamadaka and SenGupta (2001) <doi:10.1142/4031>, removal of cardinal biases is based on the approach introduced in van Bergen, Ma, Pratte, & Jehee (2015) <doi:10.1038/nn.4150> and Chetverikov and Jehee (2023) <doi:10.1038/s41467-023-43251-w>.

Patients Mental Health (MH) status, Substance Use (SU) status, and concurrent MH/SU status in the American/Canadian Healthcare Administrative Databases can be identified. The detection is based on given parameters of interest by clinicians including the list of plausible ICD MH/SU codes (3/4/5 characters), the required number of visits of hospital for MH/SU , the required number of visits of service physicians for MH/SU, and the maximum time span within MH visits, within SU visits, and, between MH and SU visits. Methods are described in: Khan S <https://pubmed.ncbi.nlm.nih.gov/29044442/>, Keen C, et al. (2021) <doi:10.1111/add.15580>, Lavergne MR, et al. (2022) <doi:10.1186/s12913-022-07759-z>, Casillas, S M, et al. (2022) <doi:10.1016/j.abrep.2022.100464>, CIHI (2022) <https://www.cihi.ca/en>, CDC (2024) <https://www.cdc.gov>, WHO (2019) <https://icd.who.int/en>.

This package provides a compilation of tests for hypotheses regarding covariance and correlation matrices for one or more groups. The hypothesis can be specified through a corresponding hypothesis matrix and a vector or by choosing one of the basic hypotheses, while for the structure test, only the latter works. Thereby Monte-Carlo and Bootstrap-techniques are used, and the respective method must be chosen, and the functions provide p-values and mostly also estimators of calculated covariance matrices of test statistics. For more details on the methodology, see Sattler et al. (2022) <doi:10.1016/j.jspi.2021.12.001>, Sattler and Pauly (2024) <doi:10.1007/s11749-023-00906-6>, and Sattler and Dobler (2025) <doi:10.48550/arXiv.2310.11799>.

Computes the cosine-correlation coefficient for measuring the degree of linear dependence among variables in a multidimensional context. The package implements the generalized cosine-correlation theorem for p-1 variables, providing a quantitative assessment of interrelationships within experimental frameworks. This methodology extends classical correlation measures to higher-dimensional spaces using a dimensional exploration approach based on time scale calculus.

Fetches the Cornell Lab of Ornithology Open Tree of Life (clootl) tree in a specified taxonomy. Optionally prune it to a given set of study taxa. Provide a recommended citation list for the studies that informed the extracted tree. Tree generated as described in McTavish et al. (2024) <doi:10.1101/2024.05.20.595017>.

This package provides a data package with 2 main package variables: signature and etiology'. The signature variable contains the latest mutational signature profiles released on COSMIC <https://cancer.sanger.ac.uk/signatures/> for 3 mutation types: * Single base substitutions in the context of preceding and following bases, * Doublet base substitutions, and * Small insertions and deletions. The etiology variable provides the known or hypothesized causes of signatures. cosmicsig stands for COSMIC signatures. Please run ?'cosmicsig for more information.

Sample size estimation in cluster (group) randomized trials. Contains traditional power-based methods, empirical smoothing (Rotondi and Donner, 2009), and updated meta-analysis techniques (Rotondi and Donner, 2012).

This package performs forward model selection, using the C-index/concordance in survival analysis models.

Using polygenic scores (PGS, or PRS/GRS for binary outcomes), this package allows to investigate shared predisposition between different conditions, and do fast association analysis, export plots and views of the PGS distribution using ggplot2 object.

This package provides R utilities to build unlevered and levered discounted cash flow (DCF) tables for commercial real estate (CRE) assets. Functions generate bullet and amortising debt schedules, compute credit metrics such as debt coverage ratios (DCR), debt service coverage ratios (DSCR), interest coverage ratios, debt yield ratios, and forward loan-to-value ratios (LTV) based on net operating income (NOI). The toolkit evaluates refinancing feasibility under alternative market scenarios and supports end-to-end scenario execution from a YAML (YAML Ain't Markup Language) configuration file parsed with yaml'. Includes helpers for sensitivity analysis, covenant diagnostics, and reproducible vignettes.

Probability mass function, distribution function, quantile function and random generation for the Complex Triparametric Pearson (CTP) and Complex Biparametric Pearson (CBP) distributions developed by Rodriguez-Avi et al (2003) <doi:10.1007/s00362-002-0134-7>, Rodriguez-Avi et al (2004) <doi:10.1007/BF02778271> and Olmo-Jimenez et al (2018) <doi:10.1080/00949655.2018.1482897>. The package also contains maximum-likelihood fitting functions for these models.

This package provides a convenient set of wrapper functions to install pharmacometric packages and Shiny applications developed by Certara PMX and Integrated Drug Development (iDD). The functions ensure the successful installation of packages from non-standard repositories.

Functionality for segmenting individual trees from a forest stand scanned with a close-range (e.g., terrestrial or mobile) laser scanner. The complete workflow from a raw point cloud to a complete tabular forest inventory is provided. The package contains several algorithms for detecting tree bases and a graph-based algorithm to attach all remaining points to these tree bases. It builds heavily on the lidR package. A description of the segmentation algorithm can be found in Larysch et al. (2025) <doi:10.1007/s10342-025-01796-z>.

Includes commands for bootstrapping and permutation tests, a command for created grouped bar plots, and a demo of the quantile-normal plot for data drawn from different distributions.

This package provides functions for cost-sensitive multi-criteria ensemble selection (CSMES) (as described in De bock et al. (2020) <doi:10.1016/j.ejor.2020.01.052>) for cost-sensitive learning under unknown cost conditions.

Eases the use of ecotoxicological effect models. Can simulate common toxicokinetic-toxicodynamic (TK/TD) models such as General Unified Threshold models of Survival (GUTS) and Lemna. It can derive effects and effect profiles (EPx) from scenarios. It supports the use of tidyr workflows employing the pipe symbol. Time-consuming tasks can be parallelized.

Implementation of the empirical method to derive log2 counts per million (CPM) cutoff to filter out lowly expressed genes using ERCC spike-ins as described in Goll and Bosinger et.al (2022)<doi:10.1101/2022.06.23.497396>. This package utilizes the synthetic mRNA control pairs developed by the External RNA Controls Consortium (ERCC) (ERCC 1 / ERCC 2) that are spiked into sample pairs at known ratios at various absolute abundances. The relationship between the observed and expected fold changes is then used to empirically determine an optimal log2 CPM cutoff for filtering out lowly expressed genes.

Categorize links and nodes from multiple networks in 3 categories: Common links (alpha) specific links (gamma), and different links (beta). Also categorizes the links into sub-categories and groups. The package includes a visualization tool for the networks. More information about the methodology can be found at: Gysi et. al., 2018 <arXiv:1802.00828>.

Copernicus Atmosphere Monitoring Service (CAMS) radiations service provides time series of global, direct, and diffuse irradiations on horizontal surface, and direct irradiation on normal plane for the actual weather conditions as well as for clear-sky conditions. The geographical coverage is the field-of-view of the Meteosat satellite, roughly speaking Europe, Africa, Atlantic Ocean, Middle East. The time coverage of data is from 2004-02-01 up to 2 days ago. Data are available with a time step ranging from 15 min to 1 month. For license terms and to create an account, please see <http://www.soda-pro.com/web-services/radiation/cams-radiation-service>.

We design algorithms with linear time complexity with respect to the dimension for three commonly studied correlation structures, including exchangeable, decaying-product and K-dependent correlation structures, and extend the algorithms to generate binary data of general non-negative correlation matrices with quadratic time complexity. Jiang, W., Song, S., Hou, L. and Zhao, H. "A set of efficient methods to generate high-dimensional binary data with specified correlation structures." The American Statistician. See <doi:10.1080/00031305.2020.1816213> for a detailed presentation of the method.

This is a simple R package that allows to measure the stated preferences using traditional conjoint analysis method.