An implementation of double generalized linear model (DGLM) building with variable selection procedures and handling of interaction terms and other complex situations. We also provide a method of handling convergence issues within the dglm() function. The package offers a simulation function for generating simulated data for testing purposes and utilizes the forward stepwise variable selection procedure in model-building. It also provides a new custom bootstrap function for mean and standard deviation estimation and functions for building crossplots and squareplots from a data set.

This package contains the function calendR() for creating fully customizable monthly and yearly calendars (colors, fonts, formats, ...) and even heatmap calendars. In addition, it allows saving the calendars in ready to print A4 format PDF files.

This package provides tools for causal structure learning from observational data, with emphasis on temporally ordered variables. The package implements the Temporal Peterâ Clark (TPC) algorithm (Petersen, Osler & Ekstrøm, 2021; <doi:10.1093/aje/kwab087>), the Temporal Greedy Equivalence Search (TGES) algorithm (Larsen, Ekstrøm & Petersen, 2025; <doi:10.48550/arXiv.2502.06232>) and Temporal Fast Causal Inference (TFCI). It provides a unified framework for specifying background knowledge, which can be incorporated into the implemented algorithms from the R packages bnlearn (Scutari, 2010; <doi:10.18637/jss.v035.i03>) and pcalg (Kalish et al., 2012; <doi:10.18637/jss.v047.i11>), as well as the Java library Tetrad (Scheines et al., 1998; <doi:10.1207/s15327906mbr3301_3>). The package further includes utilities for visualization, comparison, and evaluation of graph structures, facilitating performance evaluation and methodological studies.

Detection of outliers in circular-circular regression models, modifying its and estimating of models parameters.

Calculates the chilling and heat accumulation for studies of the temperate fruit trees. The models in this package are: Utah (Richardson et al., 1974, ISSN:0018-5345), Positive Chill Units - PCU (Linsley-Noaks et al., 1995, ISSN:1017-0316), GDH-A - Growing Degree Hours by Anderson et al.(1986, ISSN:0567-7572), GDH-R - Growing Degree Hours by Richardson et al.(1975, ISSN:0018-5345), North Carolina (Shaltout e Unrath, 1983, ISSN:0003-1062), Landsberg Model (Landsberg, 1974, ISSN:0305-7364), Q10 Model (Bidabe, 1967, ISSN:0031-9368), Jones Model (Jones et al., 2013 <DOI:10.1111/j.1438-8677.2012.00590.x>), Low-Chill Model (Gilreath and Buchanan, 1981, ISSN:0003-1062), Model for Cherry "Sweetheart" (Guak and Nielsen, 2013 <DOI:10.1007/s13580-013-0140-9>), Model for apple "Gala" (Guak and Nielsen, 2013 <DOI:10.1007/s13580-013-0140-9>), Taiwan Model (Lu et al., 2012 <DOI:10.17660/ActaHortic.2012.962.35>), Dynamic Model (Fishman et al., 1987, ISSN:0022-5193) adapted from the function Dynamic_Model() of the chillR package (Luedeling, 2018), Unified Model (Chuine et al., 2016 <DOI:10.1111/gcb.13383>) and Heat Restriction model.

Contrast trees represent a new approach for assessing the accuracy of many types of machine learning estimates that are not amenable to standard (cross) validation methods; see "Contrast trees and distribution boosting", Jerome H. Friedman (2020) <doi:10.1073/pnas.1921562117>. In situations where inaccuracies are detected, boosted contrast trees can often improve performance. Functions are provided to to build such trees in addition to a special case, distribution boosting, an assumption free method for estimating the full probability distribution of an outcome variable given any set of joint input predictor variable values.

This package provides functions for evaluating and visualizing predictive model performance (specifically: binary classifiers) in the field of customer scoring. These metrics include lift, lift index, gain percentage, top-decile lift, F1-score, expected misclassification cost and absolute misclassification cost. See Berry & Linoff (2004, ISBN:0-471-47064-3), Witten and Frank (2005, 0-12-088407-0) and Blattberg, Kim & Neslin (2008, ISBN:978â 0â 387â 72578â 9) for details. Visualization functions are included for lift charts and gain percentage charts. All metrics that require class predictions offer the possibility to dynamically determine cutoff values for transforming real-valued probability predictions into class predictions.

There are diverse purposes such as biomarker confirmation, novel biomarker discovery, constructing predictive models, model-based prediction, and validation. It handles binary, continuous, and time-to-event outcomes at the sample or patient level. - Biomarker confirmation utilizes established functions like glm() from stats', coxph() from survival', surv_fit(), and ggsurvplot() from survminer'. - Biomarker discovery and variable selection are facilitated by three LASSO-related functions LASSO2(), LASSO_plus(), and LASSO2plus(), leveraging the glmnet R package with additional steps. - Eight versatile modeling functions are offered, each designed for predictive models across various outcomes and data types. 1) LASSO2(), LASSO_plus(), LASSO2plus(), and LASSO2_reg() perform variable selection using LASSO methods and construct predictive models based on selected variables. 2) XGBtraining() employs XGBoost for model building and is the only function not involving variable selection. 3) Functions like LASSO2_XGBtraining(), LASSOplus_XGBtraining(), and LASSO2plus_XGBtraining() combine LASSO-related variable selection with XGBoost for model construction. - All models support prediction and validation, requiring a testing dataset comparable to the training dataset. Additionally, the package introduces XGpred() for risk prediction based on survival data, with the XGpred_predict() function available for predicting risk groups in new datasets. The methodology is based on our new algorithms and various references: - Hastie et al. (1992, ISBN 0 534 16765-9), - Therneau et al. (2000, ISBN 0-387-98784-3), - Kassambara et al. (2021) <https://CRAN.R-project.org/package=survminer>, - Friedman et al. (2010) <doi:10.18637/jss.v033.i01>, - Simon et al. (2011) <doi:10.18637/jss.v039.i05>, - Harrell (2023) <https://CRAN.R-project.org/package=rms>, - Harrell (2023) <https://CRAN.R-project.org/package=Hmisc>, - Chen and Guestrin (2016) <doi:10.48550/arXiv.1603.02754>, - Aoki et al. (2023) <doi:10.1200/JCO.23.01115>.

Implement tableGrob object as a clickable image map. The clickableImageMap package is designed to be more convenient and more configurable than the edit() function. Limitations that I have encountered with edit() are cannot control (1) positioning (2) size (3) appearance and formatting of fonts In contrast, when the table is implemented as a tableGrob', all of these features are controllable. In particular, the ggplot2 grid system allows exact positioning of the table relative to other graphics etc.

The cito package provides a user-friendly interface for training and interpreting deep neural networks (DNN). cito simplifies the fitting of DNNs by supporting the familiar formula syntax, hyperparameter tuning under cross-validation, and helps to detect and handle convergence problems. DNNs can be trained on CPU, GPU and MacOS GPUs. In addition, cito has many downstream functionalities such as various explainable AI (xAI) metrics (e.g. variable importance, partial dependence plots, accumulated local effect plots, and effect estimates) to interpret trained DNNs. cito optionally provides confidence intervals (and p-values) for all xAI metrics and predictions. At the same time, cito is computationally efficient because it is based on the deep learning framework torch'. The torch package is native to R, so no Python installation or other API is required for this package.

Set of functions for the easy analyses of conditioning data.

Computes a novel metric of affinity between two entities based on their co-occurrence (using binary presence/absence data). The metric and its maximum likelihood estimator (alpha hat) were advanced in Mainali, Slud, et al, 2021 <doi:10.1126/sciadv.abj9204>. Four types of confidence intervals and median interval were developed in Mainali and Slud, 2022 <doi:10.1101/2022.11.01.514801>. The `finches` dataset is bundled with the package.

This package provides functions to compute and plot Coverage Probability Excursion (CoPE) sets for real valued functions on a 2-dimensional domain. CoPE sets are obtained from repeated noisy observations of the function on the entire domain. They are designed to bound the excursion set of the target function at a given level from above and below with a predefined probability. The target function can be a parameter in spatially-indexed linear regression. Support by NIH grant R01 CA157528 is gratefully acknowledged.

Filter CpGs based on Intra-class Correlation Coefficients (ICCs) when replicates are available. ICCs are calculated by fitting linear mixed effects models to all samples including the un-replicated samples. Including the large number of un-replicated samples improves ICC estimates dramatically. The method accommodates any replicate design.

This package provides interface to the Copernicus Data Space Ecosystem API <https://dataspace.copernicus.eu/analyse/apis>, mainly for searching the catalog of available data from Copernicus Sentinel missions and obtaining the images for just the area of interest based on selected spectral bands. The package uses the Sentinel Hub REST API interface <https://dataspace.copernicus.eu/analyse/apis/sentinel-hub> that provides access to various satellite imagery archives. It allows you to access raw satellite data, rendered images, statistical analysis, and other features. This package is in no way officially related to or endorsed by Copernicus.

Plots calibration curves and computes statistics for assessing calibration performance. See Lasai et al. (2025) <doi:10.48550/arXiv.2503.08389>, De Cock Campo (2023) <doi:10.48550/arXiv.2309.08559> and Van Calster et al. (2016) <doi:10.1016/j.jclinepi.2015.12.005>.

Provide the CrossClustering algorithm (Tellaroli et al. (2016) <doi:10.1371/journal.pone.0152333>), which is a partial clustering algorithm that combines the Ward's minimum variance and Complete Linkage algorithms, providing automatic estimation of a suitable number of clusters and identification of outlier elements.

Routines doing cone projection and quadratic programming, as well as doing estimation and inference for constrained parametric regression and shape-restricted regression problems. See Mary C. Meyer (2013)<doi:10.1080/03610918.2012.659820> for more details.

Regression splines that handle a mix of continuous and categorical (discrete) data often encountered in applied settings. I would like to gratefully acknowledge support from the Natural Sciences and Engineering Research Council of Canada (NSERC, <https://www.nserc-crsng.gc.ca>), the Social Sciences and Humanities Research Council of Canada (SSHRC, <https://www.sshrc-crsh.gc.ca>), and the Shared Hierarchical Academic Research Computing Network (SHARCNET, <https://www.sharcnet.ca>). We would also like to acknowledge the contributions of the GNU GSL authors. In particular, we adapt the GNU GSL B-spline routine gsl_bspline.c adding automated support for quantile knots (in addition to uniform knots), providing missing functionality for derivatives, and for extending the splines beyond their endpoints.

This package provides a framework for specifying and running flexible linear-time reachability-based algorithms for graphical causal inference. Rule tables are used to encode and customize the reachability algorithm to typical causal and probabilistic reasoning tasks such as finding d-connected nodes or more advanced applications. For more information, see Wienöbst, Weichwald and Henckel (2025) <doi:10.48550/arXiv.2506.15758>.

Robust regression methods for compositional data. The distribution of the estimates can be approximated with various bootstrap methods. These bootstrap methods are available for the compositional as well as for standard robust regression estimates. This allows for direct comparison between them.

Create and manipulate study cohorts in data mapped to the Observational Medical Outcomes Partnership Common Data Model.

Utility functions that allow checking the basic validity of a function argument or any other value, including generating an error and assigning a default in a single line of code. The main purpose of the package is to provide simple and easily readable argument checking to improve code robustness.

The theory of cooperative games with transferable utility offers useful insights into the way parties can share gains from cooperation and secure sustainable agreements, see e.g. one of the books by Chakravarty, Mitra and Sarkar (2015, ISBN:978-1107058798) or by Driessen (1988, ISBN:978-9027727299) for more details. A comprehensive set of tools for cooperative game theory with transferable utility is provided. Users can create special families of cooperative games, like e.g. bankruptcy games, cost sharing games and weighted voting games. There are functions to check various game properties and to compute five different set-valued solution concepts for cooperative games. A large number of point-valued solution concepts is available reflecting the diverse application areas of cooperative game theory. Some of these point-valued solution concepts can be used to analyze weighted voting games and measure the influence of individual voters within a voting body. There are routines for visualizing both set-valued and point-valued solutions in the case of three or four players.