S3 classes for multivariate optimization using the desirability function by Derringer and Suich (1980).

Several tools for handling block-matrix diagonals and similar constructs are implemented. Block-diagonal matrices can be extracted or removed using two small functions implemented here. In addition, non-square matrices are supported. Block diagonal matrices occur when two dimensions of a data set are combined along one edge of a matrix. For example, trade-flow data in the decompr and gvc packages have each country-industry combination occur along both edges of the matrix.

Identification of hub genes in a gene co-expression network from gene expression data. The differential network analysis for two contrasting conditions leads to the identification of various types of hubs like Housekeeping, Unique to stress (Disease) and Unique to control (Normal) hub genes.

This package provides a set of tools for empirical analysis of diversity (a number and frequency of different types in a population) and similarity (a number and frequency of shared types in two populations) in biological or ecological systems.

Build graph/network structures using functions for stepwise addition and deletion of nodes and edges. Work with data available in tables for bulk addition of nodes, edges, and associated metadata. Use graph selections and traversals to apply changes to specific nodes or edges. A wide selection of graph algorithms allow for the analysis of graphs. Visualize the graphs and take advantage of any aesthetic properties assigned to nodes and edges.

This package contains data sets, examples and software from the book Design of Observational Studies by Paul R. Rosenbaum, New York: Springer, <doi:10.1007/978-1-4419-1213-8>, ISBN 978-1-4419-1212-1.

Dependent censoring regression models for survival multivariate data. These models are based on extensions of the frailty models, capable to accommodating the dependence between failure and censoring times, with Weibull and piecewise exponential marginal distributions. Theoretical details regarding the models implemented in the package can be found in Schneider et al. (2019) <doi:10.1002/bimj.201800391>.

Item focussed recursive partitioning for simultaneous selection of items and variables that induce Differential Item Functioning (DIF) in dichotomous or polytomous items.

This is an R implementation of Fast and Scalable Learning of Sparse Changes in High-Dimensional Gaussian Graphical Model Structure (DIFFEE). The DIFFEE algorithm can be used to fast estimate the differential network between two related datasets. For instance, it can identify differential gene network from datasets of case and control. By performing data-driven network inference from two high-dimensional data sets, this tool can help users effectively translate two aggregated data blocks into knowledge of the changes among entities between two Gaussian Graphical Model. Please run demo(diffeeDemo) to learn the basic functions provided by this package. For further details, please read the original paper: Beilun Wang, Arshdeep Sekhon, Yanjun Qi (2018) <arXiv:1710.11223>.

This R function implements the nonstationary Kriging model proposed by Tuo, Wu and Yu (2014) <DOI:10.1080/00401706.2013.842935> for analyzing multi-fidelity computer outputs. This function computes the maximum likelihood estimates for the model parameters as well as the predictive means and variances of the exact solution.

This package provides a graphical user interface (GUI) to the functions implemented in the R package DQAstats'. Publication: Mang et al. (2021) <doi:10.1186/s12911-022-01961-z>.

This package contains the normalizing and variance stabilizing Data-Driven Haar-Fisz algorithm. Also contains related algorithms for simulating from certain microarray gene intensity models and evaluation of certain transformations. Contains cDNA and shipping credit flow data.

This package provides a specific and comprehensive framework for the analyses of time-to-event data in agriculture. Fit non-parametric and parametric time-to-event models. Compare time-to-event curves for different experimental groups. Plots and other displays. It is particularly tailored to the analyses of data from germination and emergence assays. The methods are described in Onofri et al. (2022) "A unified framework for the analysis of germination, emergence, and other time-to-event data in weed science", Weed Science, 70, 259-271 <doi:10.1017/wsc.2022.8>.

Piecewise linear segmentation of ordered data by a dynamic programming algorithm. The algorithm was developed for time series data, e.g. growth curves, and for genome-wide read-count data from next generation sequencing, but is broadly applicable. Generic implementations of dynamic programming routines allow to scan for optimal segmentation parameters and test custom segmentation criteria ("scoring functions").

Output graphics to EMF+/EMF.

This package provides a collection of supervised discretization algorithms. It can also be grouped in terms of top-down or bottom-up, implementing the discretization algorithms.

This package provides functions for the calculation and plotting of synchrony in tree growth from tree-ring width chronologies (TRW index). It combines variance-covariance (VCOV) mixed modelling with functions that quantify the degree to which the TRW chronologies contain a common temporal signal. It also implements temporal trends in spatial synchrony using a moving window. These methods can also be used with other kind of ecological variables that have temporal autocorrelation corrected.

This package performs the identification of differential risk hotspots (Briz-Redon et al. 2019) <doi:10.1016/j.aap.2019.105278> along a linear network. Given a marked point pattern lying on the linear network, the method implemented uses a network-constrained version of kernel density estimation (McSwiggan et al. 2017) <doi:10.1111/sjos.12255> to approximate the probability of occurrence across space for the type of event specified by the user through the marks of the pattern (Kelsall and Diggle 1995) <doi:10.2307/3318678>. The goal is to detect microzones of the linear network where the type of event indicated by the user is overrepresented.

Preferred methods for common analytical tasks that are undertaken across the Department, including number formatting, project templates and curated reference data.

This package performs analysis of popular experimental designs used in the field of biological research. The designs covered are completely randomized design, randomized complete block design, factorial completely randomized design, factorial randomized complete block design, split plot design, strip plot design and latin square design. The analysis include analysis of variance, coefficient of determination, normality test of residuals, standard error of mean, standard error of difference and multiple comparison test of means. The package has functions for transformation of data and yield data conversion. Some datasets are also added in order to facilitate examples.

Re-arranges a dendrogram to optimize visualisation-based cost functions.

Computes dynamical correlation estimates and percentile bootstrap confidence intervals for pairs of longitudinal responses, including consideration of lags and derivatives.

Offers statistical methods to compare diagnostic performance between two binary diagnostic tests on the same subject in clinical studies. Includes functions for generating formatted tables to display diagnostic outcomes, facilitating a clear and comprehensive comparison directly through the R console. Inspired by and extending the functionalities of the DTComPair', tableone', and gtsummary packages.

Estimation of Difference-in-Differences (DiD) estimators from de Chaisemartin et al. (2025) <doi:10.48550/arXiv.2405.04465> in Heterogeneous Adoption Designs with Quasi Untreated Groups.