Individual gene expression patterns are encoded into a series of eigenvector patterns ('WGCNA package). Using the framework of linear model-based differential expression comparisons ('limma package), time-course expression patterns for genes in different conditions are compared and analyzed for significant pattern changes. For reference, see: Greenham K, Sartor RC, Zorich S, Lou P, Mockler TC and McClung CR. eLife. 2020 Sep 30;9(4). <doi:10.7554/eLife.58993>.

An implementation of common higher order functions with syntactic sugar for anonymous function. Provides also a link to dplyr and data.table for common transformations on data frames to work around non standard evaluation by default.

This package provides a set of control charts for batch processes based on the VAR model. The package contains the implementation of T2.var and W.var control charts based on VAR model coefficients using the couple vectors theory. In each time-instant the VAR coefficients are estimated from a historical in-control dataset and a decision rule is made for online classifying of a new batch data. Those charts allow efficient online monitoring since the very first time-instant. The offline version is available too. In order to evaluate the chart's performance, this package contains functions to generate batch data for offline and online monitoring.See in Danilo Marcondes Filho and Marcio Valk (2020) <doi:10.1016/j.ejor.2019.12.038>.

Visualize one-factor data frame. Beads plot consists of diamonds of each factor of each data series. A diamond indicates average and range. Look over a data frame with many numeric columns and a factor column.

This package provides a toolbox to create and manage metadata files and configuration profiles: files used to configure the parameters and initial settings for some computer programs.

Utilities for mixed frequency data. In particular, use to aggregate and normalize tabular mixed frequency data, index dates to end of period, and seasonally adjust tabular data.

Solves quadratic programming problems using Richard L. Dykstra's cyclic projection algorithm. Routine allows for a combination of equality and inequality constraints. See Dykstra (1983) <doi:10.1080/01621459.1983.10477029> for details.

Calculates Distinctiveness Centrality in social networks. For formulas and descriptions, see Fronzetti Colladon and Naldi (2020) <doi:10.1371/journal.pone.0233276>.

Build a Dockerfile straight from your R session. dockerfiler allows you to create step by step a Dockerfile, and provide convenient tools to wrap R code inside this Dockerfile.

Client for programmatic access to the South Florida Water Management District's DBHYDRO database at <https://www.sfwmd.gov/science-data/dbhydro>, with functions for accessing hydrologic and water quality data.

Read Word documents containing bibliographic references, search for corresponding DOIs using the Crossref API, and append the retrieved DOIs directly to the references. Supports parallel processing for faster retrieval and produces a new Word document with numbered references including DOIs.

Allows clinicians and researchers to compute daily dose (and subsequently days supply) for prescription refills using the following methods: Fixed window, fixed tablet, defined daily dose (DDD), and Random Effects Warfarin Days Supply (REWarDS). Daily dose is the computed dose that the patient takes every day. For medications with fixed dosing (e.g. direct oral anticoagulants) this is known and does not need to be estimated. For medications with varying dose such as warfarin, however, the daily dose should be assumed or estimated to allow measurement of drug exposure. Daysâ supply is the number of days that patientsâ supply of medication will last after each prescription fill. Estimating daysâ supply is necessary to calculate drug exposure. The package computes daysâ supply and daily dose at both the prescription and patient levels. Results at the prescription level are denoted with â -Rx-â and those at patient level are denoted with â -Pt-â .

Summarizes data frames by calculating various statistics including central tendency, dispersion, shape, and normality diagnostics. Handles numeric, character, and factor columns with NA-aware computations.

This package contains functions that check for formatting of the Subject Phenotype data set and data dictionary as specified by the National Center for Biotechnology Information (NCBI) Database of Genotypes and Phenotypes (dbGaP) <https://www.ncbi.nlm.nih.gov/gap/docs/submissionguide/>.

This package contains functions to help with generating tables with descriptive statistics. In addition, the package can display results of statistical tests for group comparisons. A wide range of test procedures is supported, and user-defined test functions can be incorporated.

This package contains data sets, examples and software from the Second Edition of "Design of Observational Studies"; see Rosenbaum, P.R. (2010) <doi:10.1007/978-1-4419-1213-8>.

This package provides the ability to display something analogous to Python's docstrings within R. By allowing the user to document their functions as comments at the beginning of their function without requiring putting the function into a package we allow more users to easily provide documentation for their functions. The documentation can be viewed just like any other help files for functions provided by packages as well.

This package provides a wrapper for the DeepL API <https://developers.deepl.com/docs>, a web service for translating texts between different languages. A DeepL API developer account is required to use the service (see <https://www.deepl.com/pro#developer>).

This package provides new types of omnibus tests which are generally much more powerful than traditional tests (including the Kolmogorov-Smirnov, Cramer-von Mises and Anderson-Darling tests),see Zhang (2002) <doi:10.1111/1467-9868.00337>.

Simulation tool to estimate the rate of success that surveys possessing user-specific characteristics have in identifying archaeological sites (or any groups of clouds of objects), given specific parameters of survey area, survey methods, and site properties. The survey approach used is largely based on the work of Kintigh (1988) <doi:10.2307/281113>.

Computational tools for meta-analysis of diagnostic accuracy test. Bootstrap-based computational methods of the confidence interval for AUC of summary ROC curve and some related AUC-based inference methods are available (Noma et al. (2021) <doi:10.1080/23737484.2021.1894408>).

Simultaneously detect the number and locations of change points in piecewise linear models under stationary Gaussian noise allowing autocorrelated random noise. The core idea is to transform the problem of detecting change points into the detection of local extrema (local maxima and local minima)through kernel smoothing and differentiation of the data sequence, see Cheng et al. (2020) <doi:10.1214/20-EJS1751>. A low-computational and fast algorithm call dSTEM is introduced to detect change points based on the STEM algorithm in D. Cheng and A. Schwartzman (2017) <doi:10.1214/16-AOS1458>.

This package provides tools for temporal disaggregation, including: (1) High-dimensional and low-dimensional series generation for simulation studies; (2) A toolkit for temporal disaggregation and benchmarking using low-dimensional indicator series as proposed by Dagum and Cholette (2006, ISBN:978-0-387-35439-2); (3) Novel techniques by Mosley, Gibberd, and Eckley (2022, <doi:10.1111/rssa.12952>) for disaggregating low-frequency series in the presence of high-dimensional indicator matrices.

This package provides R-implementation of Decision forest algorithm, which combines the predictions of multiple independent decision tree models for a consensus decision. In particular, Decision Forest is a novel pattern-recognition method which can be used to analyze: (1) DNA microarray data; (2) Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SELDI-TOF-MS) data; and (3) Structure-Activity Relation (SAR) data. In this package, three fundamental functions are provided, as (1)DF_train, (2)DF_pred, and (3)DF_CV. run Dforest() to see more instructions. Weida Tong (2003) <doi:10.1021/ci020058s>.