Dynamic treatment regime estimation and inference via G-estimation, dynamic weighted ordinary least squares (dWOLS) and Q-learning. Inference via bootstrap and recursive sandwich estimation. Estimation and inference for survival outcomes via Dynamic Weighted Survival Modeling (DWSurv). Extension to continuous treatment variables. Wallace et al. (2017) <DOI:10.18637/jss.v080.i02>; Simoneau et al. (2020) <DOI:10.1080/00949655.2020.1793341>.

Metabarcoding analysis using the DBTC package is implemented here using shiny in an interactive graphical user interface to conduct Metabarcode analyses and visualize and filter results.

This package provides a versatile toolkit for analyzing and visualizing DEXi (Decision EXpert for education) decision trees, facilitating multi-criteria decision analysis directly within R. Users can read .dxi files, manipulate decision trees, and evaluate various scenarios. It supports sensitivity analysis through Monte Carlo simulations, one-at-a-time approaches, and variance-based methods, helping to discern the impact of input variations. Additionally, it includes functionalities for generating sampling plans and an array of visualization options for decision trees and analysis results. A distinctive feature is the synoptic table plot, aiding in the efficient comparison of scenarios. Whether for in-depth decision modeling or sensitivity analysis, this package stands as a comprehensive solution. Definition of sensitivity analyses available in Carpani, Bergez and Monod (2012) <doi:10.1016/j.envsoft.2011.10.002> and detailed description of the package soon available in Alaphilippe et al. (2025) <doi:10.1016/j.simpa.2024.100729>.

This package provides the dose transition pathways (DTP) to project in advance the doses recommended by a model-based design for subsequent patients (stay, escalate, deescalate or stop early) using all the accumulated toxicity information; See Yap et al (2017) <doi: 10.1158/1078-0432.CCR-17-0582>. DTP can be used as a design and an operational tool and can be displayed as a table or flow diagram. The dtpcrm package also provides the modified continual reassessment method (CRM) and time-to-event CRM (TITE-CRM) with added practical considerations to allow stopping early when there is sufficient evidence that the lowest dose is too toxic and/or there is a sufficient number of patients dosed at the maximum tolerated dose.

Base DataSHIELD functions for the client side. DataSHIELD is a software package which allows you to do non-disclosive federated analysis on sensitive data. DataSHIELD analytic functions have been designed to only share non disclosive summary statistics, with built in automated output checking based on statistical disclosure control. With data sites setting the threshold values for the automated output checks. For more details, see citation('dsBaseClient').

Find, visualize and explore patterns of differential taxa in vegetation data (namely in a phytosociological table), using the Differential Value (DiffVal). Patterns are searched through mathematical optimization algorithms. Ultimately, Total Differential Value (TDV) optimization aims at obtaining classifications of vegetation data based on differential taxa, as in the traditional geobotanical approach (Monteiro-Henriques 2025, <doi:10.3897/VCS.140466>). The Gurobi optimizer, as well as the R package gurobi', can be installed from <https://www.gurobi.com/products/gurobi-optimizer/>. The useful vignette Gurobi Installation Guide, from package prioritizr', can be found here: <https://prioritizr.net/articles/gurobi_installation_guide.html>.

We consider a set of sample counts obtained by sampling arbitrary fractions of a finite volume containing an homogeneously dispersed population of identical objects. This package implements a Bayesian derivation of the posterior probability distribution of the population size using a binomial likelihood and non-conjugate, discrete uniform priors under sampling with or without replacement. This can be used for a variety of statistical problems involving absolute quantification under uncertainty. See Comoglio et al. (2013) <doi:10.1371/journal.pone.0074388>.

An intuitive, cross-platform graphical data analysis system. It uses menus and dialogs to guide the user efficiently through the data manipulation and analysis process, and has an excel like spreadsheet for easy data frame visualization and editing. Deducer works best when used with the Java based R GUI JGR, but the dialogs can be called from the command line. Dialogs have also been integrated into the Windows Rgui.

Diffusion Weighted Imaging (DWI) is a Magnetic Resonance Imaging modality, that measures diffusion of water in tissues like the human brain. The package contains R-functions to process diffusion-weighted data. The functionality includes diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), modeling for high angular resolution diffusion weighted imaging (HARDI) using Q-ball-reconstruction and tensor mixture models, several methods for structural adaptive smoothing including POAS and msPOAS, and a streamline fiber tracking for tensor and tensor mixture models. The package provides functionality to manipulate and visualize results in 2D and 3D.

Programmatic access to the DuckDuckGo Instant Answer API <https://api.duckduckgo.com/api>.

This package creates full factorial experimental designs and designs based on orthogonal arrays for (industrial) experiments. Provides diverse quality criteria. Provides utility functions for the class design, which is also used by other packages for designed experiments.

Dual Scaling, developed by Professor Shizuhiko Nishisato (1994, ISBN: 0-9691785-3-6), is a fundamental technique in multivariate analysis used for data scaling and correspondence analysis. Its utility lies in its ability to represent multidimensional data in a lower-dimensional space, making it easier to visualize and understand underlying patterns in complex data. This technique has been implemented to handle various types of data, including Contingency and Frequency data (CF), Multiple-Choice data (MC), Sorting data (SO), Paired-Comparison data (PC), and Rank-Order data (RO), providing users with a powerful tool to explore relationships between variables and observations in various fields, from sociology to ecology, enabling deeper and more efficient analysis of multivariate datasets.

Designed to create a basic data dictionary and append to the original dataset's attributes list. The package makes use of a tidy dataset and creates a data frame that will serve as a linker that will aid in building the dictionary. The dictionary is then appended to the list of the original dataset's attributes. The user will have the option of entering variable and item descriptions by writing code or use alternate functions that will prompt the user to add these.

This package provides a variety of methods to identify data quality issues in process-oriented data, which are useful to verify data quality in a process mining context. Builds on the class for activity logs implemented in the package bupaR'. Methods to identify data quality issues either consider each activity log entry independently (e.g. missing values, activity duration outliers,...), or focus on the relation amongst several activity log entries (e.g. batch registrations, violations of the expected activity order,...).

Fast functions for effective sample size, weighted multivariate mean, variance, and quantile computation, and weight diagnostic plot for generic importance sampling type or other probability weighted samples.

Infer progression of circadian rhythms in transcriptome data in which samples are not labeled with time of day and coverage of the circadian cycle may be incomplete. See Shilts et al. (2018) <doi:10.7717/peerj.4327>.

Bindings for additional classification models for use with the parsnip package. Models include flavors of discriminant analysis, such as linear (Fisher (1936) <doi:10.1111/j.1469-1809.1936.tb02137.x>), regularized (Friedman (1989) <doi:10.1080/01621459.1989.10478752>), and flexible (Hastie, Tibshirani, and Buja (1994) <doi:10.1080/01621459.1994.10476866>), as well as naive Bayes classifiers (Hand and Yu (2007) <doi:10.1111/j.1751-5823.2001.tb00465.x>).

Chaos theory has been hailed as a revolution of thoughts and attracting ever increasing attention of many scientists from diverse disciplines. Chaotic systems are nonlinear deterministic dynamic systems which can behave like an erratic and apparently random motion. A relevant field inside chaos theory and nonlinear time series analysis is the detection of a chaotic behaviour from empirical time series data. One of the main features of chaos is the well known initial value sensitivity property. Methods and techniques related to test the hypothesis of chaos try to quantify the initial value sensitive property estimating the Lyapunov exponents. The DChaos package provides different useful tools and efficient algorithms which test robustly the hypothesis of chaos based on the Lyapunov exponent in order to know if the data generating process behind time series behave chaotically or not.

Geodesic distance between phylogenetic trees and associated functions. The theoretical background of distory is published in Billera et al. (2001) "Geometry of the space of phylogenetic trees." <doi:10.1006/aama.2001.0759>.

This package provides methods to apply decomposition-based relative importance analysis for R functions. This package supports the application of decomposition methods by providing lapply'- or Map'-like meta-functions that compute dominance analysis (Azen, R., & Budescu, D. V. (2003) <doi:10.1037/1082-989X.8.2.129>; Grömping, U. (2007) <doi:10.1198/000313007X188252>) an extension of Shapley value regression (Lipovetsky, S., & Conklin, M. (2001) <doi:10.1002/asmb.446>) based on the values returned from other functions.

Several functions are provided for dose-response (or concentration-response) characterization from omics data. DRomics is especially dedicated to omics data obtained using a typical dose-response design, favoring a great number of tested doses (or concentrations) rather than a great number of replicates (no need of replicates). DRomics provides functions 1) to check, normalize and or transform data, 2) to select monotonic or biphasic significantly responding items (e.g. probes, metabolites), 3) to choose the best-fit model among a predefined family of monotonic and biphasic models to describe each selected item, 4) to derive a benchmark dose or concentration and a typology of response from each fitted curve. In the available version data are supposed to be single-channel microarray data in log2, RNAseq data in raw counts, or already pretreated continuous omics data (such as metabolomic data) in log scale. In order to link responses across biological levels based on a common method, DRomics also handles apical data as long as they are continuous and follow a normal distribution for each dose or concentration, with a common standard error. For further details see Delignette-Muller et al (2023) <DOI:10.24072/pcjournal.325> and Larras et al (2018) <DOI:10.1021/acs.est.8b04752>.

Compute degree days from daily min and max temperatures for modeling plant and insect development.

This package contains functions to perform copula estimation by the non-parametric Bayesian method, Dirichlet-based Polya Tree. See Ning (2018) <doi:10.1080/00949655.2017.1421194>.

Data science methods used in wind energy applications. Current functionalities include creating a multi-dimensional power curve model, performing power curve function comparison, covariate matching, and energy decomposition. Relevant works for the developed functions are: funGP() - Prakash et al. (2022) <doi:10.1080/00401706.2021.1905073>, AMK() - Lee et al. (2015) <doi:10.1080/01621459.2014.977385>, tempGP() - Prakash et al. (2022) <doi:10.1080/00401706.2022.2069158>, ComparePCurve() - Ding et al. (2021) <doi:10.1016/j.renene.2021.02.136>, deltaEnergy() - Latiffianti et al. (2022) <doi:10.1002/we.2722>, syncSize() - Latiffianti et al. (2022) <doi:10.1002/we.2722>, imptPower() - Latiffianti et al. (2022) <doi:10.1002/we.2722>, All other functions - Ding (2019, ISBN:9780429956508).