Multi-binary response models are a class of models that allow for the estimation of multiple binary outcomes simultaneously. This package provides functions to estimate and simulate these models using the Discrete Exponential-Family Models [DEFM] framework. In it, we implement the models described in Vega Yon, Valente, and Pugh (2023) <doi:10.48550/arXiv.2211.00627>. DEFMs include Exponential-Family Random Graph Models [ERGMs], which characterize graphs using sufficient statistics, which is also the core of DEFMs. Using sufficient statistics, we can describe the data through meaningful motifs, for example, transitions between different states, joint distribution of the outcomes, etc.

Tutarials of R learning easily and happily.

This package provides a specific and comprehensive framework for the analyses of time-to-event data in agriculture. Fit non-parametric and parametric time-to-event models. Compare time-to-event curves for different experimental groups. Plots and other displays. It is particularly tailored to the analyses of data from germination and emergence assays. The methods are described in Onofri et al. (2022) "A unified framework for the analysis of germination, emergence, and other time-to-event data in weed science", Weed Science, 70, 259-271 <doi:10.1017/wsc.2022.8>.

Move elements between containers in Shiny without explicitly using JavaScript'. It can be used to build custom inputs or to change the positions of user interface elements like plots or tables.

This package provides a high level API to interface over sources storing distance, dissimilarity, similarity matrices with matrix style extraction, replacement and other utilities. Currently, in-memory dist object backend is supported.

This package implements the doubly robust distribution balancing weighting proposed by Katsumata (2024) <doi:10.1017/psrm.2024.23>, which improves the augmented inverse probability weighting (AIPW) by estimating propensity scores with estimating equations suitable for the pre-specified parameter of interest (e.g., the average treatment effects or the average treatment effects on the treated) and estimating outcome models with the estimated inverse probability weights. It also implements the covariate balancing propensity score proposed by Imai and Ratkovic (2014) <doi:10.1111/rssb.12027> and the entropy balancing weighting proposed by Hainmueller (2012) <doi:10.1093/pan/mpr025>, both of which use covariate balancing conditions in propensity score estimation. The point estimate of the parameter of interest and its uncertainty as well as coefficients for propensity score estimation and outcome regression are produced using the M-estimation. The same functions can be used to estimate average outcomes in missing outcome cases.

Extends the functionality of other plotting packages (notably ggplot2') to help facilitate the plotting of data over long time intervals, including, but not limited to, geological, evolutionary, and ecological data. The primary goal of deeptime is to enable users to add highly customizable timescales to their visualizations. Other functions are also included to assist with other areas of deep time visualization.

Duplicated data can exist in different rows and columns and user may need to treat observations (rows) connected by duplicated data as one observation, e.g. companies can belong to one family (and thus: be one company) by sharing some telephone numbers. This package allows to find connected rows based on data on chosen columns and collapse it into one row.

Makes deck.gl <https://deck.gl/>, a WebGL-powered open-source JavaScript framework for visual exploratory data analysis of large datasets, available within R via the htmlwidgets package. Furthermore, it supports basemaps from mapbox <https://www.mapbox.com/> via mapbox-gl-js <https://github.com/mapbox/mapbox-gl-js>.

This package provides functions are provided that facilitate the import and analysis of SNP (single nucleotide polymorphism) and silicodart (presence/absence) data. The main focus is on data generated by DarT (Diversity Arrays Technology), however, data from other sequencing platforms can be used once SNP or related fragment presence/absence data from any source is imported. Genetic datasets are stored in a derived genlight format (package adegenet'), that allows for a very compact storage of data and metadata. Functions are available for importing and exporting of SNP and silicodart data, for reporting on and filtering on various criteria (e.g. CallRate', heterozygosity, reproducibility, maximum allele frequency). Additional functions are available for visualization (e.g. Principle Coordinate Analysis) and creating a spatial representation using maps. dartR supports also the analysis of 3rd party software package such as newhybrid', structure', NeEstimator and blast'. Since version 2.0.3 we also implemented simulation functions, that allow to forward simulate SNP dynamics under different population and evolutionary dynamics. Comprehensive tutorials and support can be found at our github repository: github.com/green-striped-gecko/dartR/. If you want to cite dartR', you find the information by typing citation('dartR') in the console.

This package provides a systematic biology tool was developed to repurpose drugs via a subpathway crosstalk network. The operation modes include 1) calculating centrality scores of SPs in the context of gene expression data to reflect the influence of SP crosstalk, 2) evaluating drug-disease reverse association based on disease- and drug-induced SPs weighted by the SP crosstalk, 3) identifying cancer candidate drugs through perturbation analysis. There are also several functions used to visualize the results.

This package provides tools to create and manipulate probability distributions using S3. Generics pdf(), cdf(), quantile(), and random() provide replacements for base R's d/p/q/r style functions. Functions and arguments have been named carefully to minimize confusion for students in intro stats courses. The documentation for each distribution contains detailed mathematical notes.

Distributed Online Goodness-of-Fit Test can process the distributed datasets. The philosophy of the package is described in Guo G.(2024) <doi:10.1016/j.apm.2024.115709>.

Tissue-specific enrichment analysis to assess lists of candidate genes or RNA-Seq expression profiles. Pei G., Dai Y., Zhao Z. Jia P. (2019) deTS: Tissue-Specific Enrichment Analysis to decode tissue specificity. Bioinformatics, In submission.

This package provides extra functions to manipulate dendrograms that build on the base functions provided by the stats package. The main functionality it is designed to add is the ability to colour all the edges in an object of class dendrogram according to cluster membership i.e. each subtree is coloured, not just the terminal leaves. In addition it provides some utility functions to cut dendrogram and hclust objects and to set/get labels.

Statistical hypothesis testing using the Delta method as proposed by Deng et al. (2018) <doi:10.1145/3219819.3219919>. This method replaces the standard variance estimation formula in the Z-test with an approximate formula derived via the Delta method, which can account for within-user correlation.

This package performs parametric and non-parametric estimation and simulation of drifting semi-Markov processes. The definition of parametric and non-parametric model specifications is also possible. Furthermore, three different types of drifting semi-Markov models are considered. These models differ in the number of transition matrices and sojourn time distributions used for the computation of a number of semi-Markov kernels, which in turn characterize the drifting semi-Markov kernel. For the parametric model estimation and specification, several discrete distributions are considered for the sojourn times: Uniform, Poisson, Geometric, Discrete Weibull and Negative Binomial. The non-parametric model specification makes no assumptions about the shape of the sojourn time distributions. Semi-Markov models are described in: Barbu, V.S., Limnios, N. (2008) <doi:10.1007/978-0-387-73173-5>. Drifting Markov models are described in: Vergne, N. (2008) <doi:10.2202/1544-6115.1326>. Reliability indicators of Drifting Markov models are described in: Barbu, V. S., Vergne, N. (2019) <doi:10.1007/s11009-018-9682-8>. We acknowledge the DATALAB Project <https://lmrs-num.math.cnrs.fr/projet-datalab.html> (financed by the European Union with the European Regional Development fund (ERDF) and by the Normandy Region) and the HSMM-INCA Project (financed by the French Agence Nationale de la Recherche (ANR) under grant ANR-21-CE40-0005).

Fits dose-response models utilizing a Bayesian model averaging approach as outlined in Gould (2019) <doi:10.1002/bimj.201700211> for both continuous and binary responses. Longitudinal dose-response modeling is also supported in a Bayesian model averaging framework as outlined in Payne, Ray, and Thomann (2024) <doi:10.1080/10543406.2023.2292214>. Functions for plotting and calculating various posterior quantities (e.g. posterior mean, quantiles, probability of minimum efficacious dose, etc.) are also implemented. Copyright Eli Lilly and Company (2019).

Probability mass function, distribution function, quantile function, random generation and parameter estimation for the discrete inverse Weibull distribution.

Model cell type heterogeneity of bulk renal cell carcinoma. The observed gene expression in bulk tumor sample is modeled by a log-normal distribution with the location parameter structured as a linear combination of the component-specific gene expressions.

Various functions to import, verify, process and plot high-resolution dendrometer data using daily and stem-cycle approaches as described in Deslauriers et al, 2007 <doi:10.1016/j.dendro.2007.05.003>. For more details about the package please see: Van der Maaten et al. 2016 <doi:10.1016/j.dendro.2016.06.001>.

Automatic generation of finite state machine models of dynamic decision-making that both have strong predictive power and are interpretable in human terms. We use an efficient model representation and a genetic algorithm-based estimation process to generate simple deterministic approximations that explain most of the structure of complex stochastic processes. We have applied the software to empirical data, and demonstrated it's ability to recover known data-generating processes by simulating data with agent-based models and correctly deriving the underlying decision models for multiple agent models and degrees of stochasticity.

This package implements fast Monte Carlo simulations for goodness-of-fit (GOF) tests for discrete distributions. This includes tests based on the Chi-squared statistic, the log-likelihood-ratio (G^2) statistic, the Freeman-Tukey (Hellinger-distance) statistic, the Kolmogorov-Smirnov statistic, the Cramer-von Mises statistic as described in Choulakian, Lockhart and Stephens (1994) <doi:10.2307/3315828>, and the root-mean-square statistic, see Perkins, Tygert, and Ward (2011) <doi:10.1016/j.amc.2011.03.124>.

Fit and explore Drift Diffusion Models (DDMs), a common tool in psychology for describing decision processes in simple tasks. It can handle both time-independent and time-dependent DDMs. You either choose prebuilt models or create your own, and the package takes care of model predictions and parameter estimation. Model predictions are derived via the numerical solutions provided by Richter, Ulrich, and Janczyk (2023, <doi:10.1016/j.jmp.2023.102756>).