Useful functions for various DDI (Data Documentation Initiative) related inputs and outputs. Converts data files to and from DDI, SPSS, Stata, SAS, R and Excel, including user declared missing values.

By systematically aggregating and processing textual reports from earthquakes, floods, storms, wildfires, and other natural disasters, the framework enables a holistic assessment of crisis narratives. Intelligent cleaning and normalization techniques transform raw commentary into structured data, ensuring precise extraction of disaster-specific insights. Collective sentiments of affected communities are quantitatively scored and qualitatively categorized, providing a multifaceted view of societal responses under duress. Interactive geographic maps and temporal charts illustrate the evolution and spatial dispersion of emotional reactions and impact indicators.

This package creates testthat tests from roxygen examples using simple tags.

Multi-binary response models are a class of models that allow for the estimation of multiple binary outcomes simultaneously. This package provides functions to estimate and simulate these models using the Discrete Exponential-Family Models [DEFM] framework. In it, we implement the models described in Vega Yon, Valente, and Pugh (2023) <doi:10.48550/arXiv.2211.00627>. DEFMs include Exponential-Family Random Graph Models [ERGMs], which characterize graphs using sufficient statistics, which is also the core of DEFMs. Using sufficient statistics, we can describe the data through meaningful motifs, for example, transitions between different states, joint distribution of the outcomes, etc.

This package produces SPSS- and SAS-like output for linear discriminant function analysis and canonical correlation analysis. The methods are described in Manly & Alberto (2017, ISBN:9781498728966), Rencher (2002, ISBN:0-471-41889-7), and Tabachnik & Fidell (2019, ISBN:9780134790541).

Detection of runs of homozygosity and of heterozygosity in diploid genomes using two methods: sliding windows (Purcell et al (2007) <doi:10.1086/519795>) and consecutive runs (Marras et al (2015) <doi:10.1111/age.12259>).

Pulls together a collection of datasets from Miguel de Carvalho research articles and books. Including, for example: - de Carvalho (2012) <doi:10.1016/j.jspi.2011.08.016>; - de Carvalho et al (2012) <doi:10.1080/03610926.2012.709905>; - de Carvalho et al (2012) <doi:10.1016/j.econlet.2011.09.007>); - de Carvalho and Davison (2014) <doi:10.1080/01621459.2013.872651>; - de Carvalho and Rua (2017) <doi:10.1016/j.ijforecast.2015.09.004>; - de Carvalho et al (2023) <doi:10.1002/sta4.560>; - de Carvalho et al (2022) <doi:10.1007/s13253-021-00469-9>; - Palacios et al (2025) <doi:10.1214/24-BA1420>.

Statistical methods and related graphical representations for the Desirability of Outcome Ranking (DOOR) methodology. The DOOR is a paradigm for the design, analysis, interpretation of clinical trials and other research studies based on the patient centric benefit risk evaluation. The package provides functions for generating summary statistics from individual level/summary level datasets, conduct DOOR probability-based inference, and visualization of the results. For more details of DOOR methodology, see Hamasaki and Evans (2025) <doi:10.1201/9781003390855>. For more explanation of the statistical methods and the graphics, see the technical document and user manual of the DOOR Shiny apps at <https://methods.bsc.gwu.edu>.

This package provides a comprehensive approach for identifying and estimating change points in multivariate time series through various statistical methods. Implements the multiple change point detection methodology from Ryan & Killick (2023) <doi:10.1080/00401706.2023.2183261> and a novel estimation methodology from Fotopoulos et al. (2023) <doi:10.1007/s00362-023-01495-0> generalized to fit the detection methodologies. Performs both detection and estimation of change points, providing visualization and summary information of the estimation process for each detected change point.

Detects and filters damaged cells in single-cell RNA sequencing (scRNA-seq) data using a novel approach inspired by DoubletFinder'. Damage is detected by measuring the extent to which cells deviate from artificially damaged profiles of themselves, simulated through the probabilistic escape of cytoplasmic RNA. As output, a damage score ranging from 0 to 1 is given for each cell providing an intuitive scale for filtering that is standardised across cell types, samples, and experiments.

Designed for genomic and proteomic data analysis, enabling unbiased PubMed searching, protein interaction network visualization, and comprehensive data summarization. This package aims to help users identify novel targets within their data sets based on protein network interactions and publication precedence of target's association with research context based on literature precedence. Methods in this package are described in detail in: Douglas et al. (2025) <doi:10.1039/D5MO00160A>. Key functionalities of this package also leverage methodologies from previous works, such as: - Szklarczyk et al. (2023) <doi:10.1093/nar/gkac1000> - Winter (2017) <doi:10.32614/RJ-2017-066>.

Creating dendrochronological networks based on the similarity between tree-ring series or chronologies. The package includes various functions to compare tree-ring curves building upon the dplR package. The networks can be used to visualise and understand the relations between tree-ring curves. These networks are also very useful to estimate the provenance of wood as described in Visser (2021) <DOI:10.5334/jcaa.79> or wood-use within a structure/context/site as described in Visser and Vorst (2022) <DOI:10.1163/27723194-bja10014>.

An add-on package to DImodels for the fitting of biodiversity and ecosystem function relationship study data with multiple ecosystem function responses and/or time points. This package uses the multivariate and repeated measures Diversity-Interactions (DI) methods developed by Kirwan et al. (2009) <doi:10.1890/08-1684.1>, Finn et al. (2013) <doi:10.1111/1365-2664.12041>, and Dooley et al. (2015) <doi:10.1111/ele.12504>.

This package provides data transformations, estimation utilities, predictive evaluation measures and simulation functions for discrete time survival analysis.

This package provides sample size and power calculations when the treatment time-lag effect is present and the lag duration is either homogeneous across the individual subject, or varies heterogeneously from individual to individual within a certain domain and following a specific pattern. The methods used are described in Xu, Z., Zhen, B., Park, Y., & Zhu, B. (2017) <doi:10.1002/sim.7157>.

This package contains one main function deduped() which speeds up slow, vectorized functions by only performing computations on the unique values of the input and expanding the results at the end.

This package provides a framework to help construct R data packages in a reproducible manner. Potentially time consuming processing of raw data sets into analysis ready data sets is done in a reproducible manner and decoupled from the usual R CMD build process so that data sets can be processed into R objects in the data package and the data package can then be shared, built, and installed by others without the need to repeat computationally costly data processing. The package maintains data provenance by turning the data processing scripts into package vignettes, as well as enforcing documentation and version checking of included data objects. Data packages can be version controlled on GitHub', and used to share data for manuscripts, collaboration and reproducible research.

Implementations of the multiple testing procedures for discrete tests described in the paper Döhler, Durand and Roquain (2018) "New FDR bounds for discrete and heterogeneous tests" <doi:10.1214/18-EJS1441>. The main procedures of the paper (HSU and HSD), their adaptive counterparts (AHSU and AHSD), and the HBR variant are available and are coded to take as input the results of a test procedure from package DiscreteTests', or a set of observed p-values and their discrete support under their nulls. A shortcut function to obtain such p-values and supports is also provided, along with a wrapper allowing to apply discrete procedures directly to data.

Data Analysis using Bootstrap-Coupled ESTimation. Estimation statistics is a simple framework that avoids the pitfalls of significance testing. It uses familiar statistical concepts: means, mean differences, and error bars. More importantly, it focuses on the effect size of one's experiment/intervention, as opposed to a false dichotomy engendered by P values. An estimation plot has two key features: 1. It presents all datapoints as a swarmplot, which orders each point to display the underlying distribution. 2. It presents the effect size as a bootstrap 95% confidence interval on a separate but aligned axes. Estimation plots are introduced in Ho et al., Nature Methods 2019, 1548-7105. <doi:10.1038/s41592-019-0470-3>. The free-to-view PDF is located at <https://www.nature.com/articles/s41592-019-0470-3.epdf?author_access_token=Euy6APITxsYA3huBKOFBvNRgN0jAjWel9jnR3ZoTv0Pr6zJiJ3AA5aH4989gOJS_dajtNr1Wt17D0fh-t4GFcvqwMYN03qb8C33na_UrCUcGrt-Z0J9aPL6TPSbOxIC-pbHWKUDo2XsUOr3hQmlRew%3D%3D>.

With bivariate data, it is possible to calculate 2-dimensional kernel density estimates that return polygons at given levels of probability. densityarea returns these polygons for analysis, including for calculating their area.

Traditional phasing programs are limited to diploid organisms. Our method modifies Li and Stephens algorithm with Markov chain Monte Carlo (MCMC) approaches, and builds a generic framework that allows haplotype searches in a multiple infection setting. This package is primarily developed as part of the Pf3k project, which is a global collaboration using the latest sequencing technologies to provide a high-resolution view of natural variation in the malaria parasite Plasmodium falciparum. Parasite DNA are extracted from patient blood sample, which often contains more than one parasite strain, with unknown proportions. This package is used for deconvoluting mixed haplotypes, and reporting the mixture proportions from each sample.

This package provides functions to impute large gaps within multivariate time series based on Dynamic Time Warping methods. Gaps of size 1 or inferior to a defined threshold are filled using simple average and weighted moving average respectively. Larger gaps are filled using the methodology provided by Phan et al. (2017) <DOI:10.1109/MLSP.2017.8168165>: a query is built immediately before/after a gap and a moving window is used to find the most similar sequence to this query using Dynamic Time Warping. To lower the calculation time, similar sequences are pre-selected using global features. Contrary to the univariate method (package DTWBI'), these global features are not estimated over the sequence containing the gap(s), but a feature matrix is built to summarize general features of the whole multivariate signal. Once the most similar sequence to the query has been identified, the adjacent sequence to this window is used to fill the gap considered. This function can deal with multiple gaps over all the sequences componing the input multivariate signal. However, for better consistency, large gaps at the same location over all sequences should be avoided.

Imputation of mixed-type and compositional data with neural networks. The architecture (number and size of hidden layers, dropout, activation, optimiser) is user-configurable. See Templ (2021) <doi:10.1007/978-3-030-71175-7>.

Non-iterative estimator for the cumulative distribution of a doubly truncated variable. de Uña-à lvarez J. (2018) <doi:10.1007/978-3-319-73848-2_37>.