Offers a flexible and user-friendly interface for visualizing conditional effects from a broad range of regression models, including mixed-effects and generalized additive (mixed) models. Compatible model types include lm(), rlm(), glm(), glm.nb(), betareg(), and gam() (from mgcv'); nonlinear models via nls(); generalized least squares via gls(); and survival models via coxph() (from survival'). Mixed-effects models with random intercepts and/or slopes can be fitted using lmer(), glmer(), glmer.nb(), glmmTMB(), or gam() (from mgcv', via smooth terms). Plots are rendered using base R graphics with extensive customization options. Approximate confidence intervals for nls() and betareg() models are computed using the delta method. Robust standard errors for rlm() are computed using the sandwich estimator (Zeileis 2004) <doi:10.18637/jss.v011.i10>. For beta regression using betareg', see Cribari-Neto and Zeileis (2010) <doi:10.18637/jss.v034.i02>. For mixed-effects models with lme4', see Bates et al. (2015) <doi:10.18637/jss.v067.i01>. For models using glmmTMB', see Brooks et al. (2017) <doi:10.32614/RJ-2017-066>. Methods for generalized additive models using mgcv follow Wood (2017) <doi:10.1201/9781315370279>.

This package provides tools for fitting the Extended Empirical Saddlepoint (EES) density of Fasiolo et al. (2018) <doi:10.1214/18-EJS1433>.

Equating of multiple forms using Item Response Theory (IRT) methods. See Battauz (2025) <doi:10.18637/jss.v115.i11> for a detailed description of the package. See Battauz M. (2017) <doi:10.1007/s11336-016-9517-x>, Battauz and Leoncio (2023) <doi:10.1177/01466216231151702> and Haberman S. J. (2009) <doi:10.1002/j.2333-8504.2009.tb02197.x>) for the methods to link multiple test forms.

Software of esDesign is developed to implement the adaptive enrichment designs with sample size re-estimation presented in Lin et al. (2021) <doi: 10.1016/j.cct.2020.106216>. In details, three-proposed trial designs are provided, including the AED1-SSR (or ES1-SSR), AED2-SSR (or ES2-SSR) and AED3-SSR (or ES3-SSR). In addition, this package also contains several widely used adaptive designs, such as the Marker Sequential Test (MaST) design proposed Freidlin et al. (2014) <doi:10.1177/1740774513503739>, the adaptive enrichment designs without early stopping (AED or ES), the sample size re-estimation procedure (SSR) based on the conditional power proposed by Proschan and Hunsberger (1995), and some useful functions. In details, we can calculate the futility and/or efficacy stopping boundaries, the sample size required, calibrate the value of the threshold of the difference between subgroup-specific test statistics, conduct the simulation studies in AED, SSR, AED1-SSR, AED2-SSR and AED3-SSR.

This package provides a consistent representation of year-based time scales as a numeric vector with an associated era'. There are built-in era definitions for many year numbering systems used in contemporary and historic calendars (e.g. Common Era, Islamic Hijri years); year-based time scales used in archaeology, astronomy, geology, and other palaeosciences (e.g. Before Present, SI-prefixed annus'); and support for arbitrary user-defined eras. Years can converted from any one era to another using a generalised transformation function. Methods are also provided for robust casting and coercion between years and other numeric types, type-stable arithmetic with years, and pretty-printing in tables.

Fitting and testing multi-attribute probabilistic choice models, especially the Bradley-Terry-Luce (BTL) model (Bradley & Terry, 1952 <doi:10.1093/biomet/39.3-4.324>; Luce, 1959), elimination-by-aspects (EBA) models (Tversky, 1972 <doi:10.1037/h0032955>), and preference tree (Pretree) models (Tversky & Sattath, 1979 <doi:10.1037/0033-295X.86.6.542>).

This package provides a set of methods to access and parse live filing information from the U.S. Securities and Exchange Commission (SEC - <https://www.sec.gov/>) including company and fund filings along with all associated metadata.

Uses data and constants to calculate potential evapotranspiration (PET) and actual evapotranspiration (AET) from 21 different formulations including Penman, Penman-Monteith FAO 56, Priestley-Taylor and Morton formulations.

This cointegration based Time Delay Neural Network Model hybrid model allows the researcher to make use of the information extracted by the cointegrating vector as an input in the neural network model.

This package provides a client for the Environmental Data Initiative repository REST API. The EDI data repository <https://portal.edirepository.org/nis/home.jsp> is for publication and reuse of ecological data with emphasis on metadata accuracy and completeness. It is built upon the PASTA+ software stack <https://pastaplus-core.readthedocs.io/en/latest/index.html#> and was developed in collaboration with the US LTER Network <https://lternet.edu/>. EDIutils includes functions to search and access existing data, evaluate and upload new data, and assist other data management tasks common to repository users.

This package provides basic distribution functions for a mixture model of a Gaussian and exponential distribution.

This package provides a function that quickly computes the fine structure isotope patterns of a set of chemical formulas to a given degree of accuracy (up to the limit set by errors in floating point arithmetic). A data-set comprising the masses and isotopic abundances of individual elements is also provided and calculation of isotopic gross structures is also supported.

It provides a method based on EM algorithm to estimate the parameter of a mixture model, Sigmoid-Normal Model, where the samples come from several normal distributions (also call them subgroups) whose mean is determined by co-variable Z and coefficient alpha while the variance are homogeneous. Meanwhile, the subgroup each item belongs to is determined by co-variables X and coefficient eta through Sigmoid link function which is the extension of Logistic Link function. It uses bootstrap to estimate the standard error of parameters. When sample is indeed separable, removing estimation with abnormal sigma, the estimation of alpha is quite well. I used this method to explore the subgroup structure of HIV patients and it can be used in other domains where exists subgroup structure.

Drafting an epidemiological report in Microsoft Word format for a given disease, similar to the Annual Epidemiological Reports published by the European Centre for Disease Prevention and Control. Through standalone functions, it is specifically designed to generate each disease specific output presented in these reports and includes: - Table with the distribution of cases by Member State over the last five years; - Seasonality plot with the distribution of cases at the European Union / European Economic Area level, by month, over the past five years; - Trend plot with the trend and number of cases at the European Union / European Economic Area level, by month, over the past five years; - Age and gender bar graph with the distribution of cases at the European Union / European Economic Area level. Two types of datasets can be used: - The default dataset of dengue 2015-2019 data; - Any dataset specified as described in the vignette.

Estimation of epidemiological parameters with Laplacian-P-splines following the methodology of Gressani et al. (2022) <doi:10.1371/journal.pcbi.1010618>.

This package provides a complete rewrite and reimagining of bakR (see Vock et al. (2025) <doi:10.1371/journal.pcbi.1013179>). Designed to support a wide array of analyses of nucleotide recoding RNA-seq (NR-seq) datasets of any type, including TimeLapse-seq/SLAM-seq/TUC-seq, Start-TimeLapse-seq (STL-seq), TT-TimeLapse-seq (TT-TL-seq), and subcellular NR-seq. EZbakR extends standard NR-seq standard NR-seq mutational modeling to support multi-label analyses (e.g., 4sU and 6sG dual labeling), and implements an improved hierarchical model to better account for transcript-to-transcript variance in metabolic label incorporation. EZbakR also generalized dynamical systems modeling of NR-seq data to support analyses of premature mRNA processing and flow between subcellular compartments. Finally, EZbakR implements flexible and well-powered comparative analyses of all estimated parameters via design matrix-specified generalized linear modeling.

The purpose of Early Warning Systems (EWS) is to detect accurately the occurrence of a crisis, which is represented by a binary variable which takes the value of one when the event occurs, and the value of zero otherwise. EWS are a toolbox for policymakers to prevent or attenuate the impact of economic downturns. Modern EWS are based on the econometric framework of Kauppi and Saikkonen (2008) <doi:10.1162/rest.90.4.777>. Specifically, this framework includes four dichotomous models, relying on a logit approach to model the relationship between yield spreads and future recessions, controlling for recession risk factors. These models can be estimated in a univariate or a balanced panel framework as in Candelon, Dumitrescu and Hurlin (2014) <doi:10.1016/j.ijforecast.2014.03.015>. This package provides both methods for estimating these models and a dataset covering 13 OECD countries over a period of 45 years. In addition, this package also provides methods for the analysis of the propagation mechanisms of an exogenous shock, as well as robust confidence intervals for these response functions using a block-bootstrap method as in Lajaunie (2021). This package constitutes a useful toolbox (data and functions) for scholars as well as policymakers.

This package provides tools for training and practicing epidemiologists including methods for two-way and multi-way contingency tables.

This package provides a tool which allows users to create and evaluate ensembles of species distribution model (SDM) predictions. Functionality is offered through R functions or a GUI (R Shiny app). This tool can assist users in identifying spatial uncertainties and making informed conservation and management decisions. The package is further described in Woodman et al (2019) <doi:10.1111/2041-210X.13283>.

This package provides functions to align curves and to compute mean curves based on the elastic distance defined in the square-root-velocity framework. For more details on this framework see Srivastava and Klassen (2016, <doi:10.1007/978-1-4939-4020-2>). For more theoretical details on our methods and algorithms see Steyer et al. (2023, <doi:10.1111/biom.13706>) and Steyer et al. (2023, <arXiv:2305.02075>).

Predictors can be converted to one or more numeric representations using a variety of methods. Effect encodings using simple generalized linear models <doi:10.48550/arXiv.1611.09477> or nonlinear models <doi:10.48550/arXiv.1604.06737> can be used. There are also functions for dimension reduction and other approaches.

An eikosogram (ancient Greek for probability picture) divides the unit square into rectangular regions whose areas, sides, and widths represent various probabilities associated with the values of one or more categorical variates. Rectangle areas are joint probabilities, widths are always marginal (though possibly joint margins, i.e. marginal joint distributions of two or more variates), and heights of rectangles are always conditional probabilities. Eikosograms embed the rules of probability and are useful for introducing elementary probability theory, including axioms, marginal, conditional, and joint probabilities, and their relationships (including Bayes theorem as a completely trivial consequence). They provide advantages over Venn diagrams for this purpose, particularly in distinguishing probabilistic independence, mutually exclusive events, coincident events, and associations. They also are useful for identifying and understanding conditional independence structure. Eikosograms can be thought of as mosaic plots when only two categorical variates are involved; the layout is quite different when there are more than two variates. Only one categorical variate, designated the "response", presents on the vertical axis and all others, designated the "conditioning" variates, appear on the horizontal. In this way, conditional probability appears only as height and marginal probabilities as widths. The eikosogram is ideal for response models (e.g. logistic models) but equally useful when no variate is distinguished as the response. In such cases, each variate can appear in turn as the response, which is handy for assessing conditional independence in discrete graphical models (i.e. "Bayesian networks" or "BayesNets"). The eikosogram and its value over Venn diagrams in teaching probability is described in W.H. Cherry and R.W. Oldford (2003) <https://math.uwaterloo.ca/~rwoldfor/papers/eikosograms/paper.pdf>, its value in exploring conditional independence structure and relation to graphical and log-linear models is described in R.W. Oldford (2003) <https://math.uwaterloo.ca/~rwoldfor/papers/eikosograms/independence/paper.pdf>, and a number of problems, puzzles, and paradoxes that are easily explained with eikosograms are given in R.W. Oldford (2003) <https://math.uwaterloo.ca/~rwoldfor/papers/eikosograms/examples/paper.pdf>.

This package provides functions to quantify animal dominance hierarchies. The major focus is on Elo rating and its ability to deal with temporal dynamics in dominance interaction sequences. For static data, David's score and de Vries I&SI are also implemented. In addition, the package provides functions to assess transitivity, linearity and stability of dominance networks. See Neumann et al (2011) <doi:10.1016/j.anbehav.2011.07.016> for an introduction.

This package provides a Shiny'-based toolkit for item/test analysis. It is designed for multiple-choice, true-false, and open-ended questions. The toolkit is usable with datasets in 1-0 or other formats. Key analyses include difficulty, discrimination, response-option analysis, reports. The classical test theory methods used are described in Ebel & Frisbie (1991, ISBN:978-0132892314).